It can regenerate bits of its body. Ancient Mexicans revered it as a mischievous, shape-shifting god.

They named it axolotl — translation: "water monster" — and it's a "salamander with a Mona Lisa smile," reports the Washington Post, "an alien-looking creature with a permanent grin and a crown of feathery gills". But while there's over a million in the world's scientific laboratories, back in its only natural habitat — the canals of Lake Xochimilco in Mexico City — it's on the brink of extinction. In hopes of preventing the annihilation of a species with mystifying traits, ecologists at Mexico's National Autonomous University are giving the public the chance to virtually adopt an axolotl. For $30, $180 or $360, donors can choose the sex, age and name of the little buddy they get to call theirs for a month, six months or a year, respectively. The axolotls stay in Mexico, but donors receive an adoption kit with an infographic, the axolotl's identification card, a certificate of adoption and a personalized thank-you letter.

The campaign also includes options to buy an axolotl a meal for $10 or to fix up one of their homes for $50. And for those wanting to splurge a bit more, participants can adopt the axolotl's refuge of chinampas — the artificial islands that dot Lake Xochimilco — for one, six or 12 months starting at $450. The funds will go toward building refuges for the axolotl and restoring its habitat, which has been devastated by the effects of Mexico City's urbanization over the last decades, said Luis Zambrano, an ecologist at Mexico's National Autonomous University.

"A species can't be a species without its habitat," Zambrano said.
Axolotls have "helped scientists understand how organs develop in vertebrates, uncover the causes of the birth defect spina bifida and discover thyroid hormones..."

"The salamanders have also become beloved exotic pets — to the point that 'there's claw machines in Japan that let you pick up an axolotl to take home,' Zambrano added."

An anonymous reader writes: Amazon just inked a deal with chief competitor and Elon Musk-helmed SpaceX to launch internet-beaming satellites -- a move that comes even as Amazon founder Jeff Bezos pursues his own space dreams with his own rocket company, Blue Origin, and as SpaceX builds its own internet constellation.

While Musk and Bezos have notoriously been publicly competitive and have a history of openly sparring on social media, with Musk regularly making crude jokes about Bezos and Blue Origin, it is not uncommon for business rivals to team up in the world of rocket launches. Some Amazon satellites will still ride on a large rocket made by Blue Origin, dubbed the New Glenn. But it's been delayed for years and will make its launch debut next year at the earliest.

An anonymous reader quotes a report from Motherboard: On Wednesday, a group of military and military-adjacent scientists gathered at a conference to discuss the possibility of creating a super soldier. They discussed breeding programs, Marvel movies, The Matrix, and the various technologies the Pentagon is researching with the goal of creating a real life super soldier complete with cybernetic implants and thorny ethical issues surrounding bodily autonomy. The talk happened at the The Interservice/Industry Training, Simulation and Education Conference, or I/ITSEC, an annual conference where military leaders come to talk shop and simulation corporations gather to demo new products. It's the kind of place where execs and generals don virtual reality helmets and talk about the virtues of VR sims. You could even catch members of congress talking about the importance of simulations and war. "Winning the war of cognition by pushing readiness and lethality boundaries," reads the official poster for the 2019 I/ITSEC.

It was here, in Orlando, Florida, where five illustrious members of the military-industrial complex gathered to discuss super soldiers at the "Black Swan -- Dawn of the Super Soldier" panel. Lauren Reinerman-Jones, an analyst from Defense Acquisition University, moderated a panel that included U.S. Army Developmental Command representatives George Matook and Irwin Hudson, research scientist J.J. Walcutt, and Richard McKinley, who works on "non-invasive brain stimulation" for the Air Force. I/TSEC advertised the panel in its program with a picture of the experts next to a posing Master Chief, the genetically enhanced super soldier from the Halo video game franchise. Throughout the conversation, which covered the nuts and bolts of what's possible now and what's about to be possible along with various ethical concerns, references to science fiction and fantasy stories were common. Some of the ideas discussed include synthetic blood, pain-numbing stimulants, limb regeneration, and non-invasive brain stimulation. The discussion references the John Scalzi book about a near future where Earth wages war by offering the elderly new youthful bodies in exchange for military service.

They also discuss the ethical and legal concerns surrounding the creation of super soldiers, as well as the societal norms and potential risks. "What risks are we willing to take? There's all these wonderful things we can do," Matook said. "We don't want a fair fight. We really don't, this is not an honorable thing. We want our guys to be over-matching any possible enemies, right? So why aren't we giving them pharmaceutical enhancements? Why are we making them run all week when we could just be giving them steroids? There's all these other things you could do if you change societal norms and ethics. And laws, in some cases."

The discussion concludes with considerations about the long-term effects, reversibility of enhancements, and the potential ownership of enhanced individuals by the government. "So if you do these kinds of changes to an individual, what do you do when their service is up? What happens? Or are they just literally owned by the government for life," asks Reinerman-Jones. Hudson replied with a grim joke: "Termination."

The Space Weather Prediction Center is closely watching the arrival of a super-hot plasma eruption, known as a coronal mass ejection (CME), that will slam into Earth tonight, writes longtime Slashdot reader StyleChief. Images of the huge sunspot "rotating to face the earth" can be viewed here. The Space Weather Prediction Center reports: With 3 CMEs already inbound, the addition of a 4th, full halo CME has prompted SWPC forecasters to upgrade the G2 Watch on 01 Dec to a G3 Watch. This faster-moving halo CME is progged to merge with 2 of the 3 upstream CMEs, all arriving at Earth on 01 Dec. G3 (Strong) conditions are now likely on 01 Dec. Continue to monitor spaceweather.gov for the latest updates. "The rapid Earth-bound CME left the sun on Nov. 29 during a powerful M9.8-class solar flare eruption," reports Space.com. "But it isn't alone."

"The speedy plasma outburst will merge with several slower upstream CMEs that left the sun a day earlier (Nov. 28), creating a 'Cannibal CME' that will likely trigger a strong geomagnetic storm akin to a Nov. 5 event that supercharged auroras and STEVE around the world."

Traumatic memories had their own neural mechanism, brain scans showed, which may help explain their vivid and intrusive nature. From a report: At the root of post-traumatic stress disorder, or PTSD, is a memory that cannot be controlled. It may intrude on everyday activity, thrusting a person into the middle of a horrifying event, or surface as night terrors or flashbacks. Decades of treatment of military veterans and sexual assault survivors have left little doubt that traumatic memories function differently from other memories. A group of researchers at Yale University and the Icahn School of Medicine at Mount Sinai set out to find empirical evidence of those differences.

The team conducted brain scans of 28 people with PTSD while they listened to recorded narrations of their own memories. Some of the recorded memories were neutral, some were simply "sad," and some were traumatic. The brain scans found clear differences, the researchers reported in a paper published on Thursday in the journal Nature Neuroscience. The people listening to the sad memories, which often involved the death of a family member, showed consistently high engagement of the hippocampus, part of the brain that organizes and contextualizes memories. When the same people listened to their traumatic memories -- of sexual assaults, fires, school shootings and terrorist attacks -- the hippocampus was not involved.

[...] Indeed, the authors conclude in the paper, "traumatic memories are not experienced as memories as such," but as "fragments of prior events, subjugating the present moment." The traumatic memories appeared to engage a different area of the brain -- the posterior cingulate cortex, or P.C.C., which is usually involved in internally directed thought, like introspection or daydreaming. The more severe the person's PTSD symptoms were, the more activity appeared in the P.C.C. What is striking about this finding is that the P.C.C. is not known as a memory region, but one that is engaged with "processing of internal experience," Dr. Schiller said.

Astronomers have discovered six planets orbiting a bright star in perfect resonance. The star system, 100 light-years from Earth, was described on Wednesday in a paper published in the journal Nature. From a report: The discovery of the system could give astronomers a unique opportunity to trace the evolution of these worlds to when they first formed, and potentially offer insights into how our solar system got to be the way it is today. "It's like looking at a fossil," said Rafael Luque, an astronomer at the University of Chicago who led the study. "The orbits of the planets today are the same as they were a billion years ago."

Researchers think that when planets first form, their orbits around a star are in sync. That is, the time it takes for one planet to waltz around its host star might be the same amount of time it takes for a second planet to circle exactly twice, or exactly three times. Systems that line up like this are known as orbital resonances. But, despite the theory, finding resonances in the Milky Way is rare. Only 1 percent of planetary systems still preserve this symmetry.

Most of the time, planetary orbits get knocked out of sync by an event that upsets the gravitational balance of the system. That could be a close encounter with another star, the formation of a massive planet like Jupiter, or a giant impact from space on one planet that causes a ripple effect in other orbits. When this happens, Dr. Luque said, planetary orbits become too chaotic to mathematically describe, and knowledge of their evolution is indecipherable. Astronomers are lucky to find even one pair of exoplanets in resonance. But in the newly discovered star system, there are a whopping five pairs, because all six planets have orbits that are in sync with one another. Dr. Luque described it as "the 1 percent of the 1 percent."

An anonymous reader quotes a report from The Guardian: A new era of medical discoveries, treatments and cures is on the horizon, researchers say, following the announcement that an unprecedented trove of genetic information is to be made available to scientists. Health researchers from around the world can now apply to study the whole genomes of half a million people enrolled in UK Biobank, a biomedical research project that has compiled detailed health and lifestyle records on individuals since it began 20 years ago. The move on Thursday amounts to the largest number of whole-genome sequences ever released for medical research. The sequences will be used with UK Biobank's records and other data to delve deeply into the genetics of everything -- from people's risk of obesity, diabetes, heart disease, cancer and other conditions, to individuals' sleep and exercise patterns.

Researchers believe the new data will allow them to calculate people's individual risk scores for a raft of cancers and other diseases, and so work out who could benefit most from early screening. They should also gain a deeper understanding of serious genetic conditions such as Huntington's and motor neurone disease, which have often been studied in small numbers of severely affected patients. Health experts from academia, the government, industry and charities can apply for access though they have to be approved and study the genomes through a protected database stripped of identifying details such as names, addresses, birth dates, and GP information. "Until 2021 scientists could study only about 1% of the DNA of UK Biobank volunteers -- the fraction that encodes proteins," notes the report. "Since then, whole genomes have been released for 200,000 participants, but work continued to sequence all of the 500,000 volunteers."

"With that number of whole genomes in hand, researchers will be able to find much rarer genes which drive diseases, including those that behave like switches and turn other genes on and off."

Jennifer Ouellette reports via Ars Technica: Back in 2012, a crowdfunding effort on Indigogo successfully raised the funds necessary to purchase the Wardenclyffe Tower site on Long Island, New York, where Serbian inventor Nikola Tesla once tried to build an ambitious wireless transmission station. The goal was to raise additional funds to build a $20 million Tesla Science Center there, with a museum, an educational center, and a technological innovation program. The nonprofit group behind the project finally broke ground this April after years of basic restoration work -- only to experience a devastating setback last week, two days before Thanksgiving, when a fire broke out.

Over 100 firefighters from 17 local departments responded and battled the flames throughout the night, as residual embers led to two additional outbreaks. One firefighter sustained bruised ribs after falling off a ladder, but there were no other injuries or fatalities. Once the blaze was extinguished, the TSC group called in their engineers to assess the damage and make recommendations for repairs. While an investigation is ongoing as to the cause of the fire, Fire Chief Sean McCarrick said during a press conference on Tuesday, November 28, that they had ruled out arson. According to project architect Mark Thaler, there was nothing flammable in the lab that could have caused the fire, although the back buildings had wood-frame roofs. The original brick building, designed by Stanford White, is still standing, although there is considerable damage to the structure of the roof, steel girders, chimney, cupola, and a portion of a wall. Some elements have been irreparably destroyed, but fortunately all museum artifacts in TSC's collection were stored offsite. The most pressing concern is that water from the firehoses saturated the brick walls, according to Thaler, since the upcoming colder winter temperatures could freeze that moisture and cause the brick work to break apart and collapse. The engineers have also recommended adding strategic wall supports to both the interior and exterior to shore up the structure.

All of this comes with a hefty price tag: $3 million for immediate remediation to seal the roof and dry the building in order to stave off further damage. The building was insured, but that insurance won't come close to covering the cost. The TSC group has set up a 60-day Indiegogo campaign to raise those funds, which is separate from the $14 million it had already raised toward their targeted $20 million goal. "The best way to help right now is to donate if you can," said TSC Executive Director Marc Alessi. "We've never needed it more. We need to secure this lab, stop the water intrusion and future damage. And then we need to complete this project." [...] "Buildings burn down and can then be rebuilt," said John Gaiman, deputy county executive for Suffolk County. "The ideas behind them, the person, the history, the narrative that was created over 100 years ago still exists, and that will continue."

The United States and China are pursuing parallel scientific tracks. To solve crises on multiple fronts, the two roads need to become one, Nature's editorial board wrote Wednesday. From the post: It's no secret that research collaborations between China and the United States -- among other Western countries -- are on a downward trajectory. Early indicators of a possible downturn have been confirmed by more sources. A report from Japan's Ministry of Education, Culture, Sports, Science and Technology, published in August, for instance, stated that the number of research articles co-authored by scientists in the two countries had fallen in 2021, the first annual drop since 1993. Meanwhile, data from Nature Index show that China-based scientists' propensity to collaborate internationally has been waning, when looking at the authorship of papers in the Index's natural-science journals.

Nature reported last month that China's decoupling from the countries loosely described as the West mirrors its strengthening of science links with low- and middle-income countries (LMICs), as part of its Belt and Road Initiative. There are many good reasons for China to be boosting science in LMICs, which could sorely do with greater research funding and capacity building. But this is also creating parallel scientific systems -- one centred on North America and Europe, and the other on China. The biggest challenges faced by humanity, from combating climate change to ending poverty, are embodied in a globally agreed set of targets, the United Nations Sustainable Development Goals (SDGs).

Approaching them without shared knowledge can only slow down progress by creating competing systems for advancing and implementing solutions. It's a scenario that the research community must be more aware of and work to avoid. Nature Index offers some reasons as to why collaboration between China and the West is declining. Travel restrictions during the COVID-19 pandemic took their toll, limiting collaborations and barring new ones from being forged. Geopolitical tensions have led many Western governments to restrict their research partnerships with China, on national-security grounds, and vice versa.

A study of more than 2 million people's internet use found no "smoking gun" for widespread harm to mental health from online activities such as browsing social media and gaming, despite widely claimed concerns that mobile apps can cause depression and anxiety. From a report: Researchers at the Oxford Internet Institute, who said their study was the largest of its kind, said they found no evidence to support "popular ideas that certain groups are more at risk" from the technology. However, Andrew Przybylski, professor at the institute -- part of the University of Oxford -- said that the data necessary to establish a causal connection was "absent" without more co-operation from tech companies. If apps do harm mental health, only the companies that build them have the user data that could prove it, he said.

"The best data we have available suggests that there is not a global link between these factors," said Przybylski, who carried out the study with Matti Vuorre, a professor at Tilburg University. Because the "stakes are so high" if online activity really did lead to mental health problems, any regulation aimed at addressing it should be based on much more "conclusive" evidence, he added. "Global Well-Being and Mental Health in the Internet Age" was published in the journal Clinical Psychological Science on Tuesday. In their paper, Przybylski and Vuorre studied data on psychological wellbeing from 2.4 million people aged 15 to 89 in 168 countries between 2005 and 2022, which they contrasted with industry data about growth in internet subscriptions over that time, as well as tracking associations between mental health and internet adoption in 202 countries from 2000-19.

A team of researchers at the Medical Research Council's Laboratory of Molecular Biology has developed a prototype cryo-electron microscopy (cryo-EM) microscope that, despite being significantly cheaper than high-end machines, has successfully solved protein structures with near-atomic resolution. The findings have been published in the journal Proceedings of the National Academy of Sciences. Science Magazine reports: [MB physicist Chris Russo] wants a manufacturer to commercialize his team's design, which he believes could be built and sold for $500,000. That's within reach of a new hire's startup package, or one of the regular equipment grants offered by the National Institutes of Health (NIH) or National Science Foundation, says Bridget Carragher, founding technical director of the Chan Zuckerberg Imaging Institute. "It would be a marvelous machine," she says. "Everyone who wants to do structural biology could do it." [...] One of the team's key insights was that the electron beam does not need the energies typically used in high-end cryo-EM microscopes. Levels of 100 kiloelectronvolts (KeV) -- one-third as high -- suffice to reveal molecular structure, and they reduce costs by eliminating the need for a regulated gas, sulfur hexafluoride, to snuff out sparks. The team also saw room for improvement in the system of lenses that focuses the electrons and the detector that captures them after they probe the sample.

With the resulting prototype, the LMB group determined the structure of 11 diverse proteins. One was the iron-storing protein apoferritin, which has become a benchmark for cryo-EM resolution records. The LMB researchers mapped it at 2.6 angstroms -- 2.6 times the diameter of a hydrogen atom. That's not as high as the record cryo-EM resolution of 1.2 angstroms, but plenty good enough to make an atomic model, Russo says. And the process was fast. Because the microscope sat in the same lab as the freezing stage, the team could quickly check that its samples were good enough, rather than waiting weeks for results from a high-end machine. "Every single structure was done in less than a day," Russo says. Thermo Fisher Scientific, which makes a top-end machine, says it is already expanding the cryo-EM market. In 2020, it began to sell a lower cost option, called Tundra, that operates at 100 KeV. "I would say that there are universities that probably never believed they could own cryo-EM that now have the tools," says Trisha Rice, a vice president who heads the company's cryo-EM business. Indeed, Rajan's university just ordered one for $1.5 million.

Russo says Tundra is a step in the right direction, but his team's innovations could make cryo-EM even cheaper. For example, he says, Tundra dials back the energy on a simplified version of the costly electron source used in top-end microscopes, whereas the electron gun on the LMB prototype was designed for 100 KeV from scratch. But he understands that commercializing his team's design would require large investments by potential manufacturers. "We're talking to all of them," Russo says. "But at the end of the day, it's up to them."

Rooting out manipulation should not depend on dedicated amateurs who take personal legal risks for the greater good. From a story on Financial Times: As the Oxford university psychologist Dorothy Bishop has written, we only know about the ones who get caught. In her view, our "relaxed attitude" to the scientific fraud epidemic is a "disaster-in-waiting." The microbiologist Elisabeth Bik, a data sleuth who specialises in spotting suspect images, might argue the disaster is already here: her Patreon-funded work has resulted in over a thousand retractions and almost as many corrections. That work has been mostly done in Bik's spare time, amid hostility and threats of lawsuits. Instead of this ad hoc vigilantism, Bishop argues, there should be a proper police force, with an army of scientists specifically trained, perhaps through a masters degree, to protect research integrity.

It is a fine idea, if publishers and institutions can be persuaded to employ them (Spandidos, a biomedical publisher, has an in-house anti-fraud team). It could help to scupper the rise of the "paper mill," an estimated $1bn industry in which unscrupulous researchers can buy authorship on fake papers destined for peer-reviewed journals. China plays an outsize role in this nefarious practice, set up to feed a globally competitive "publish or perish" culture that rates academics according to how often they are published and cited. Peer reviewers, mostly unpaid, don't always spot the scam. And as the sheer volume of science piles up -- an estimated 3.7mn papers from China alone in 2021 -- the chances of being rumbled dwindle. Some researchers have been caught on social media asking to opportunistically add their names to existing papers, presumably in return for cash.

The Hill published this warning from an Information Sciences assistant professor: Since 1980, more than 40,000 scientific publications have been retracted. They either contained errors, were based on outdated knowledge or were outright frauds... Yet these zombie publications continue to be cited and used, unwittingly, to support new arguments. Why? Almost always it's because nobody noticed they had been retracted...

Just by citing a zombie publication, new research becomes infected: A single unreliable citation can threaten the reliability of the research that cites it, and that infection can cascade, spreading across hundreds of papers. A 2019 paper on childhood cancer, for example, cites 51 different retracted papers, making its research likely impossible to salvage. For the scientific record to be a record of the best available knowledge, we need to take a knowledge maintenance perspective on the scholarly literature... And we need to build on that knowledge, not on the errors and fraud...

Slow science, living articles and reducing the pressure to publish are among the interventions that could help. We need a healthy, trustworthy ecosystem that rewards effort, not just results... Individuals and organizations that do the work of science must ensure that the work doesn't end at publication. Sometimes, it is just the beginning.

An anonymous reader shared this report from the Washington Post: In 2024, a new spacecraft will hurtle toward Jupiter in a bid to learn whether its moon Europa is capable of supporting life. The craft will carry more than high-tech sensors: It also will bear a poem and hundreds of thousands of human names.

Yours could be one of them.

NASA is asking people to submit their names ahead of the mission's October 2024 launch. Those submitted by the end of 2023 will go into space on the Europa Clipper spacecraft, which should enter Jupiter's orbit in 2030... They'll eventually be stenciled onto a dime-sized microchip in microscopic writing, then attached to a metal plate engraved with the poem that will accompany the craft.
700,000 names have been submitted so far — and they'll all be carried a distance of over 1.8 billion miles.

They'll travel through space with a poem that ends by describing what we humans on earth are made of — including "a need to call out through the dark."

The world's biggest iceberg is on the move after more than 30 years being stuck to the ocean floor. From a report: The iceberg, called A23a, split from the Antarctic coastline in 1986. But it swiftly grounded in the Weddell Sea, becoming, essentially, an ice island. At almost 4,000 sq km (1,500 sq miles) in area, it's more than twice the size of Greater London. The past year has seen it drifting at speed, and the berg is now about to spill beyond Antarctic waters. A23a is a true colossus, and it's not just its width that impresses.

This slab of ice is some 400m (1,312 ft) thick. For comparison, the London Shard, the tallest skyscraper in Europe, is a mere 310m tall. At the time, it was hosting a Soviet research station, which just illustrates how long ago its calving occurred. Moscow despatched an expedition to remove equipment from the Druzhnaya 1 base, fearing it would be lost. But the tabular berg didn't move far from the coast before its deep keel anchored it rigidly to the Weddell's bottom-muds.

So, why, after almost 40 years, is A23a on the move now? "I asked a couple of colleagues about this, wondering if there was any possible change in shelf water temperatures that might have provoked it, but the consensus is the time had just come," said Dr Andrew Fleming, a remote sensing expert from the British Antarctic Survey. "It was grounded since 1986 but eventually it was going to decrease (in size) sufficiently to lose grip and start moving. I spotted first movement back in 2020." A23a has put on a spurt in recent months, driven by winds and currents, and is now passing the northern tip of the Antarctic Peninsula.