An anonymous reader quotes a report from the BBC: Four astronauts evacuated from the International Space Station (ISS) have landed back on Earth after their stay in space was cut short by a month due to a "serious" medical issue. The crew's captain, Nasa astronaut Mike Fincke, exited the spacecraft first, smiling and wobbling slightly on his feet before lying down on a gurney, following normal procedures. Nasa's Zena Cardman, Japan's Kimiya Yui and cosmonaut Oleg Platonov followed, waving and beaming at cameras. "It's so good to be home!", said Cardman.

It is the first time astronauts have been evacuated due to a health issue since the station was put into Earth's orbit in 1998. The team, known as Crew-11, will now receive medical checks before being flown back to land after the splash down off the coast of California. In a news conference after splash-down, Nasa administrator Jared Isaacman said the sick astronaut is "fine right now" and in "good spirits." Judging by past Nasa communications about astronauts' health, it is unlikely that the identity of the crew member or details of the health issue will be released to the public.

Control of the ISS has been handed over to Russian cosmonaut Sergey Kud-Sverchkov and two other crew members. The astronauts arrived on the ISS on August 1 expecting to complete a standard six and a half month stay. They were due to come home in mid-February. But last week, a scheduled spacewalk by Fincke and Cardman was called off at the last minute. Hours later, Nasa revealed a crew member had become ill.

Many people who stop using weight loss drugs will return to their previous weight within two years, a new review of existing research has found. CNN adds: This rate of weight regain is significantly faster than that seen in those who have lost weight by changing other lifestyle factors, such as diet and exercise, rather than relying on GLP-1 medications, researchers from the University of Oxford report in a paper published Wednesday in The BMJ journal.

GLP-1, which stands for glucagon-like peptide-1, is a hormone naturally made by the body that helps signal to the brain and the gut that it's full and doesn't need to eat any more. Weight loss drugs mimic the action of this hormone by increasing the secretion of insulin to lower blood sugar. They also slow the movement of food through the digestive tract, which helps people feel full more quickly and for longer, and they work in the brain to reduce appetite.

An anonymous reader quotes a report from TechCrunch: Over the weekend, Neel Somani, who is a software engineer, former quant researcher, and a startup founder, was testing the math skills of OpenAI's new model when he made an unexpected discovery. After pasting the problem into ChatGPT and letting it think for 15 minutes, he came back to a full solution. He evaluated the proof and formalized it with a tool called Harmonic -- but it all checked out. "I was curious to establish a baseline for when LLMs are effectively able to solve open math problems compared to where they struggle," Somani said. The surprise was that, using the latest model, the frontier started to push forward a bit.

ChatGPT's chain of thought is even more impressive, rattling off mathematical axioms like Legendre's formula, Bertrand's postulate, and the Star of David theorum. Eventually, the model found a Math Overflow post from 2013, where Harvard mathematician Noam Elkies had given an elegant solution to a similar problem. But ChatGPT's final proof differed from Elkies' work in important ways, and gave a more complete solution to a version of the problem posed by legendary mathematician Paul Erdos, whose vast collection of unsolved problems has become a proving ground for AI.

For anyone skeptical of machine intelligence, it's a surprising result -- and it's not the only one. AI tools have become ubiquitous in mathematics, from formalization-oriented LLMs like Harmonic's Aristotle to literature review tools like OpenAI's deep research. But since the release of GPT 5.2 -- which Somani describes as "anecdotally more skilled at mathematical reasoning than previous iterations" -- the sheer volume of solved problems has become difficult to ignore, raising new questions about large language models' ability to push the frontiers of human knowledge. Somani examined the online archive of more than 1,000 Erdos conjectures. Since Christmas, 15 Erdos problems have shifted from "open" to "solved," with 11 solutions explicitly crediting AI involvement.

On GitHub, mathematician Terence Tao identifies eight Erdos problems where AI made meaningful autonomous progress and six more where it advanced work by finding and extending prior research, noting on Mastodon that AI's scalability makes it well suited to tackling the long tail of obscure, often straightforward Erdos problems.

Progress is also being accelerated by a push toward formalization, supported by tools like the open-source "proof assistant" Lean and newer AI systems such as Harmonic's Aristotle.

An anonymous reader quotes a report from DealBook: Fifteen years ago, Daniel Ek broke into America's digital-content wars with his streaming music start-up, Spotify, which has turned into a publicly traded company with a $110 billion market value. Now he and his business partner, the Swedish entrepreneur Hjalmar Nilsonne, aim to crack a higher-stakes consumer market: American health care. The pair plan to bring Neko Health, the health tech start-up they founded in 2018, to New York this spring, DealBook is first to report.

Mr. Ek and Mr. Nilsonne hope to capitalize on the growing number of prevention-minded Americans who are hungry to track their biometric data. Whether through wearables like Oura rings or more intensive screenings, consumers are turning to technology to improve their health and help spot the early onset of some big killers, including cardiovascular and metabolic diseases. The United States will be the third market, after Sweden and Britain, for Neko Health, which offers full-body diagnostic scans and is valued at roughly $1.7 billion.

[...] Mr. Nilsonne and Mr. Ek said Neko Health's big aim was to change the health care model, in which spending across much of the developed world skyrockets but longevity gains have stalled. They want to make their noninvasive scans as routine as an annual checkup. The company, which advertises its service as "a health check for your future self," did not say what the U.S. scans would cost. But in Stockholm, an hourlong visit at one of its clinics costs 2,750 Swedish krona (about $300). Prenuvo's and Ezra's most comprehensive scans can cost $3,999.

[...] Neko Health's technology differs from that of many of its U.S. rivals. It does not use M.R.I. or X-rays, instead relying on scores of sensors and cameras and a mix of proprietary and off-the-shelf technologies to measure heart function and circulation, and to photograph and map every inch of a patient's body looking for cancerous lesions. At the moment, the company's biggest challenge is scaling.

[...] Mr. Nilsonne said Neko Health scans have detected the early onset of diseases or serious medical conditions for thousands of its patients. But the medical community is divided on the need for proactive screening technologies. The fear is that mass adoption could spur a wave of false positives and send healthy people to seek follow-up medical advice, overwhelming an already swamped health care system. Mr. Ek and Mr. Nilsonne believe they have built a better solution. And now they're ready to test it in the U.S. market.

An anonymous reader shares a report: Global temperatures soared in 2025, but a NASA statement published Wednesday alongside its latest benchmark annual report makes no reference to climate change, in line with President Donald Trump's push to deny the reality of planetary heating as a result of human activities.

That marks a sharp break from last year's communications, issued under the administration of Democrat Joe Biden, which stated plainly: "This global warming has been caused by human activities" and has led to intensifying "heat waves, wildfires, intense rainfall and coastal flooding."

Last year's materials also featured lengthy quotes from the then-NASA chief and a senior scientist and included graphics and a video. By contrast, this year's release only runs through a few key figures, and amounts to a handful of paragraphs. According to the US space agency, Earth's global surface temperature in 2025 was slightly warmer than in 2023 -- albeit within a margin of error -- making it effectively tied as the second-hottest year on record after 2024.

NASA and the U.S. Department of Energy plan to deploy a nuclear fission reactor on the Moon by 2030 to provide continuous, long-duration power for lunar bases, science missions, and future Mars exploration. space & defense reports: NASA said fission surface power will provide a critical capability for long-duration missions by delivering continuous, reliable electrical power independent of sunlight, lunar night cycles or extreme temperature conditions. Unlike solar-based systems, a nuclear reactor could operate for years without refuelling, supporting habitats, science payloads, resource utilisation systems and surface mobility.

NASA Administrator Jared Isaacman said achieving long-term human presence on the Moon and future missions to Mars will require new approaches to power generation. He said closer collaboration with the Department of Energy is essential to delivering the capabilities needed to support sustained exploration and infrastructure development beyond Earth orbit. The fission surface power system is expected to produce safe, efficient and scalable electrical power, forming a foundational element of NASA's Moon-to-Mars architecture. Continuous power availability is seen as a key enabler for permanent lunar bases, in-situ resource utilisation and expanded scientific operations in permanently shadowed regions. Further reading: You Can Now Reserve a Hotel Room On the Moon For $250,000

An anonymous reader quotes a report from the Guardian: High-profile studies reporting the presence of microplastics throughout the human body have been thrown into doubt by scientists who say the discoveries are probably the result of contamination and false positives. One chemist called the concerns "a bombshell." Studies claiming to have revealed micro and nanoplastics in the brain, testes, placentas, arteries and elsewhere were reported by media across the world, including the Guardian.

There is no doubt that plastic pollution of the natural world is ubiquitous, and present in the food and drink we consume and the air we breathe. But the health damage potentially caused by microplastics and the chemicals they contain is unclear, and an explosion of research has taken off in this area in recent years. However, micro- and nanoplastic particles are tiny and at the limit of today's analytical techniques, especially in human tissue. There is no suggestion of malpractice, but researchers told the Guardian of their concern that the race to publish results, in some cases by groups with limited analytical expertise, has led to rushed results and routine scientific checks sometimes being overlooked.

The Guardian has identified seven studies that have been challenged by researchers publishing criticism in the respective journals, while a recent analysis listed 18 studies that it said had not considered that some human tissue can produce measurements easily confused with the signal given by common plastics. There is an increasing international focus on the need to control plastic pollution but faulty evidence on the level of microplastics in humans could lead to misguided regulations and policies, which is dangerous, researchers say. It could also help lobbyists for the plastics industry to dismiss real concerns by claiming they are unfounded. While researchers say analytical techniques are improving rapidly, the doubts over recent high-profile studies also raise the questions of what is really known today and how concerned people should be about microplastics in their bodies.

Researchers from the startup Overview Energy have successfully demonstrated beaming power from a moving airplane to the ground using near-infrared light. It marks the first step toward space-based solar power satellites that could someday transmit energy from orbit to existing solar farms on Earth. IEEE Spectrum reports: Overview's test transferred only a sprinkling of power, but it did it with the same components and techniques that the company plans to send to space. "Not only is it the first optical power beaming from a moving platform at any substantial range or power," says Overview CEO Marc Berte, "but also it's the first time anyone's really done a power beaming thing where it's all of the functional pieces all working together," he says. "It's the same methodology and function that we will take to space and scale up in the long term."

[...] Many researchers have settled on microwaves as their beam of choice for wireless power. But, in addition to the safety concerns about shooting such intense waves at the Earth, [Paul Jaffe, head of systems engineering] says there's another problem: microwaves are part of what he calls the "beachfront property" of the electromagnetic spectrum -- a range from 2 to 20 gigahertz that is set aside for many other applications, such as 5G cellular networks. "The fact is," Jaffe says, "if you somehow magically had a fully operational solar power satellite that used microwave power transmission in orbit today -- and a multi-kilometer-scale microwave power satellite receiver on the ground magically in place today -- you could not turn it on because the spectrum is not allocated to do this kind of transmission."

Instead, Overview plans to use less-dense, wide-field infrared waves. Existing utility-scale solar farms would be able to receive the beamed energy just like they receive the sun's energy during daylight hours. So "your receivers are already built," Berte says. The next major step is a prototype demonstrator for low Earth orbit, after which he hopes to have GEO satellites beaming megawatts of power by 2030 and gigawatts by later that decade. Plenty of doubts about the feasibility of space-based power abound. It is an exotic technology with much left to prove, including the ability to survive orbital debris and the exorbitant cost of launching the power stations. (Overview's satellite will be built on earth in a folded configuration and it will unfold after it's brought to orbit, according to the company). "Getting down the cost per unit mass for launch is a big deal," Jaffe says. "Then, it just becomes a question of increasing the specific power. A lot of the technologies we're working on at Overview are squarely focused on that."

A newly founded startup called GRU Space is taking deposits of up to $1 million to eventually build inflatable hotels on the Moon. The bet is that space needs destinations, not just rockets, even if the first customers are essentially early adopters of sci-fi optimism. Ars Technica reports: It sounds crazy, doesn't it? After all, GRU Space had, as of late December when I spoke to founder Skyler Chan, a single full-time employee aside from himself. And Chan, in fact, only recently graduated from the University of California, Berkeley. [...] The GRU in the company's name, by the way, stands for Galactic Resource Utilization. The long-term vision is to derive resources from the Moon, Mars, asteroids, and beyond to fuel human expansion into space.

If all that sounds audacious and unrealistic, well, it kind of is. But it is not without foundation. GRU Space has already received seed funding from Y Combinator, and it will go through the organization's three-month program early this year. This will help Chan refine his company's product and give him more options to raise money. Regarding his vision, you can read GRU Space's white paper here.

Presently, the company plans to fly its initial "mission" in 2029 as a 10-kg payload on a commercial lunar lander, demonstrating an inflatable structure capability and converting lunar regolith into Moon bricks using geopolymers. With its second mission, the company plans to launch a larger inflatable structure into a "lunar pit" to test a scaled-up version of its resource development capabilities.

The first hotel, an inflatable structure, would be launched in 2032 and would be capable of supporting up to four guests at a time. The next iteration beyond this would be the fancier structure, built from Moon bricks, in the style of the Palace of the Fine Arts. "SpaceX is building the FedEx to get us there, right?" Chan said. "But there has to be a destination worthy to stay in. Obviously, there is all kinds of debate around this, and what the future is going to be like. But our conviction is that the fundamental problem we have to solve, to advance humans toward the Moon and Mars, is off-world habitation. We can't keep everyone living on that first ship that sailed to North America, right? We have to build the roads and structures and offices that we live in today."

Doctors say they have achieved the previously impossible -- restoring sight and preventing blindness in people with a rare but dangerous eye conditon called hypotony. From a report: Moorfields hospital in London is the world's first dedicated clinic for the disorder and seven out of eight patients given the pioneering treatment have responded to the therapy, a pilot study shows. One of them -- the first-ever -- is Nicki Guy, 47, who is sharing her story exclusively with the BBC.

She says the results are incredible: "It's life-changing. It's given me everything back. I can see my child grow up. "I've gone from counting fingers and everything being really blurry to being able to see." Currently, she can see and read most lines of letters on an eye test chart. She is one line away from what is legally required for driving - a massive change from being partially sighted, using a magnifying glass for anything close up and having to navigate around the house and outside largely using memory.

"If my vision stays like this for the rest of my life it would be absolutely brilliant. I may not ever be able to drive again but I'll take that!" she says. With hypotony, pressure within the eyeball becomes dangerously low, leading it to cave in on itself.

A major new review by the Cochrane collaboration -- an independent network of researchers -- evaluated 73 randomized controlled trials involving about 5,000 people with depression and found that exercise matched the effectiveness of both pharmacological treatments and psychological therapies.

The biological mechanisms overlap considerably with antidepressants. "Exercise can help improve neurotransmitter function, like serotonin as well as dopamine and endorphins," said Dr. Stephen Mateka, medical director of psychiatry at Inspira Health. Dr. Nicholas Fabiano of the University of Ottawa added that exercise triggers the release of brain-derived neurotrophic factor, or BDNF, which he calls "Miracle-Gro for the brain."

Exercise has been adopted as a first-line treatment in depression guidelines globally, though Fabiano noted it remains underutilized. The meta-analysis found that combining aerobic exercise and resistance training appeared more effective than aerobic exercise alone, and that 13 to 36 workouts led to improvements in depressive symptoms. Light to moderate exercise proved as beneficial as vigorous workouts, at least initially.

"The clock is ticking" on the Hubble Space Telescope, writes the space news site Daily Galaxy, citing estimates from the unofficial "Hubble Reentry Tracker" site (which uses orbital data from the site space-track.org, created by tech integrator SAIC): While Hubble was initially launched into low Earth orbit at an altitude of around 360 miles, it has since descended to approximately 326 miles, and it continues to fall... "The solar flux levels are currently longer in duration and more elevated than previously anticipated, resulting in an earlier reentry forecast for the Hubble Space Telescope if no reboost mission is conducted," Hubble Reentry Trackersays the Hubble Reentry Tracker... ["Hubble has been reboosted three times in its history," the site points out, "all by servicing missions using the Space Shuttle."]

NASA partnered with SpaceX in 2022 to explore the feasibility of raising Hubble to its original altitude of 373 miles. Such an adjustment would have bought Hubble a few more years in orbit. However, the future of this plan remains uncertain, as NASA has not made any official announcements to move forward with it... Solar flux levels, which determine atmospheric drag, have increased in recent years, accelerating the telescope's decline. This change in solar behavior means that the possibility of Hubble reentering Earth's atmosphere in the next five to six years is quite high if no corrective action is taken. ["But it is difficult to estimate this value due to the variability of future solar flux," the site cautions. "In the best case, Hubble may not reenter for 15 more years, around 2040. In the worst case, it could reenter in 4 years..."] Once Hubble reaches an altitude of 248 miles, it is expected that it will have less than a year before reentry...

While Hubble's end may be near, there is a promising new project on the horizon: Lazuli, a privately-funded space telescope funded by former Google CEO Eric Schmidt. Lazuli aims to become the first privately-funded space telescope, and it could be the successor Hubble enthusiasts have been hoping for. Schmidt Sciences, the organization behind the telescope, plans to launch Lazuli by 2028, providing a more modern alternative to Hubble with a larger mirror and enhanced capabilities. The telescope's proposed design includes a 94-inch-wide mirror, which is a significant upgrade from Hubble's 94.5-inch mirror, and will feature updated instruments to capture more detailed data than ever before.

An R&D lab under America's Energy Department annnounced this week that "Neuromorphic computers, inspired by the architecture of the human brain, are proving surprisingly adept at solving complex mathematical problems that underpin scientific and engineering challenges."

Phys.org publishes the announcement from Sandia National Lab: In a paper published in Nature Machine Intelligence, Sandia National Laboratories computational neuroscientists Brad Theilman and Brad Aimone describe a novel algorithm that enables neuromorphic hardware to tackle partial differential equations, or PDEs — the mathematical foundation for modeling phenomena such as fluid dynamics, electromagnetic fields and structural mechanics. The findings show that neuromorphic computing can not only handle these equations, but do so with remarkable efficiency. The work could pave the way for the world's first neuromorphic supercomputer, potentially revolutionizing energy-efficient computing for national security applications and beyond...

"We're just starting to have computational systems that can exhibit intelligent-like behavior. But they look nothing like the brain, and the amount of resources that they require is ridiculous, frankly," Theilman said.For decades, experts have believed that neuromorphic computers were best suited for tasks like recognizing patterns or accelerating artificial neural networks. These systems weren't expected to excel at solving rigorous mathematical problems like PDEs, which are typically tackled by traditional supercomputers. But for Aimone and Theilman, the results weren't surprising. The researchers believe the brain itself performs complex computations constantly, even if we don't consciously realize it. "Pick any sort of motor control task — like hitting a tennis ball or swinging a bat at a baseball," Aimone said. "These are very sophisticated computations. They are exascale-level problems that our brains are capable of doing very cheaply..."

Their research also raises intriguing questions about the nature of intelligence and computation. The algorithm developed by Theilman and Aimone retains strong similarities to the structure and dynamics of cortical networks in the brain. "We based our circuit on a relatively well-known model in the computational neuroscience world," Theilman said. "We've shown the model has a natural but non-obvious link to PDEs, and that link hasn't been made until now — 12 years after the model was introduced." The researchers believe that neuromorphic computing could help bridge the gap between neuroscience and applied mathematics, offering new insights into how the brain processes information. "Diseases of the brain could be diseases of computation," Aimone said. "But we don't have a solid grasp on how the brain performs computations yet." If their hunch is correct, neuromorphic computing could offer clues to better understand and treat neurological conditions like Alzheimer's and Parkinson's.

It will be the first medical evacuation from the International space station in its 25-year history. The Guardian reports: An astronaut in the orbital laboratory reportedly fell ill with a "serious" but undisclosed issue. Nasa also had to cancel its first spacewalk of the year... The agency did not identify the astronaut or the medical problem, citing patient privacy. "Because the astronaut is absolutely stable, this is not an emergent evacuation," [chief health and medical officer Dr. James] Polk said. "We're not immediately disembarking and getting the astronaut down, but it leaves that lingering risk and lingering question as to what that diagnosis is, and that means there is some lingering risk for that astronaut onboard."
"SpaceX says it's Dragon spacecraft at the International Space Station is ready to return its four Crew-11 astronauts home in an unprecedented medical evacuation on Jan. 14 and 15," reports Space.com: The SpaceX statement came on the heels of NASA's announcement that the Crew-11 astronauts were scheduled to undock from the space station on Jan. 14 and splashdown off the coast of California early on Jan. 15. The Crew-11 Dragon spacecraft will return NASA astronauts Zena Cardman and Mike Fincke to Earth alongside Japanese astronaut Kimiya Yui and Russian cosmonaut Oleg Platanov... NASA officials opted for a "controlled medical evacuation" in order to provide the astronaut better treatment on the ground, NASA chief Jared Isaacman has said...

Dr. James Polk, NASA's chief medical officer, has said the medical issue is not an injury to the astronaut afflicted, but rather something related to the prolonged exposure to weighlessness by astronauts living and working on the International Space Station. "It's mostly having a medical issue in the difficult areas of microgravity and the suite of hardware that we operate in," Polk said.

Scientists are putting Einstein's claim that the speed of light is constant to the test. While researchers found no evidence that light's speed changes with energy, this null result dramatically tightens the constraints on quantum-gravity theories that predict even the tiniest violations. ScienceDaily reports: Special relativity rests on the principle that the laws of physics remain the same for all observers, regardless of how they are moving relative to one another. This idea is known as Lorentz invariance. Over time, Lorentz invariance became a foundational assumption in modern physics, especially within quantum theory. [...] One prediction shared by several Lorentz-invariance-violating quantum gravity models is that the speed of light may depend slightly on a photon's energy. Any such effect would have to be tiny to match existing experimental limits. However, it could become detectable at the highest photon energies, specifically in very-high-energy gamma rays.

A research team led by former UAB student Merce Guerrero and current IEEC PhD student at the UAB Anna Campoy-Ordaz set out to test this idea using astrophysical observations. The team also included Robertus Potting from the University of Algarve and Markus Gaug, a lecturer in the Department of Physics at the UAB who is also affiliated with the IEEC. Their approach relies on the vast distances light travels across the universe. If photons of different energies are emitted at the same time from a distant source, even minuscule differences in their speeds could build up into measurable delays by the time they reach Earth.

Using a new statistical technique, the researchers combined existing measurements of very-high-energy gamma rays to examine several Lorentz-invariance-violating parameters favored by theorists within the Standard Model Extension (SME). The goal was ambitious. They hoped to find evidence that Einstein's assumptions might break down under extreme conditions. Once again, Einstein's predictions held firm. The study did not detect any violation of Lorentz invariance. Even so, the results are significant. The new analysis improves previous limits by an order of magnitude, sharply narrowing where new physics could be hiding.