Researchers have discovered that in the exotic conditions of the early universe, waves of gravity may have shaken space-time so hard that they spontaneously created radiation. Universe Today reports: a team of researchers have discovered that an exotic form of parametric resonance may have even occurred in the extremely early universe. Perhaps the most dramatic event to occur in the entire history of the universe was inflation. This is a hypothetical event that took place when our universe was less than a second old. During inflation our cosmos swelled to dramatic proportions, becoming many orders of magnitude larger than it was before. The end of inflation was a very messy business, as gravitational waves sloshed back and forth throughout the cosmos.

Normally gravitational waves are exceedingly weak. We have to build detectors that are capable of measuring distances less than the width of an atomic nucleus to find gravitational waves passing through the Earth. But researchers have pointed out that in the extremely early universe these gravitational waves may have become very strong. And they may have even created standing wave patterns where the gravitational waves weren't traveling but the waves stood still, almost frozen in place throughout the cosmos. Since gravitational waves are literally waves of gravity, the places where the waves are the strongest represent an exceptional amount of gravitational energy.

The researchers found that this could have major consequences for the electromagnetic field existing in the early universe at that time. The regions of intense gravity may have excited the electromagnetic field enough to release some of its energy in the form of radiation, creating light. This result gives rise to an entirely new phenomenon: the production of light from gravity alone. There's no situation in the present-day universe that could allow this process to happen, but the researchers have shown that the early universe was a far stranger place than we could possibly imagine.

An anonymous reader quotes a report from The Guardian: Red sand shifts under the boots of the crew members. In the distance, it appears that a rocky mountain range is rising out of the Martian horizon. A thin layer of red dust coats the solar panels and equipment necessary for the year-long mission. This landscape isn't actually 145m miles away. We are in a corner of the Nasa Johnson Space Center in Houston, in a large white warehouse right next to the disc golf course and on the tram route for tourists and school groups. But starting this June, four volunteer test subjects will spend a year locked inside, pretending to live on Mars. Nasa researchers say they're doing everything they can to make it as realistic as possible so they can learn the impact that a year in isolation with limited resources has on human health. "As we move from low Earth orbit, from moon to Mars, we're going to have a lot more resource restrictions than we have on the International Space Station and we're going to be a lot further from Earth or any help from Earth," said Dr Grace Douglas, the principal investigator for the Crew Health Performance Exploration Analog, or Chapea for short.

The four crew members will live in a small housing unit that was constructed using a huge 3D printer to simulate how Nasa may create structures on the Martian surface with Martian soil. They'll conduct experiments, grow food and exercise -- and be tested regularly so scientists can learn what a year on Mars could do to the body and mind. "This is really an extreme circumstance," said Dr Suzanne Bell, who leads the Behavioral Health and Performance Laboratory at the Nasa Johnson Space Center. "You're asking for individuals to live and work together for over a one-year period. Not only will they have to get along well, but they'll also have to perform well together."

Watching four people spend a year in a 3D-printed box is Nasa's next small step toward landing humans on the surface of Mars. Nasa says it hopes to send humans to the red planet as early as the 2030s. The first mission could be a nine-month trip one-way, and could leave the astronauts on the surface for two and a half years before starting the long trip back home. Preparations for that trek are already well under way with the agency's Artemis program. Artemis is sending astronauts back to the Moon for the first time since 1972, including the first person of color and woman to walk on another celestial body. As part of the Artemis missions, Nasa is also launching Gateway, a space station that will orbit the Moon and serve as a pit stop for Mars-bound missions. Getting to the Moon means getting to Mars, and getting to Mars means testing the physical and behavioral health of a crew in isolation. That's where Chapea comes in.

According to the BBC, the Atacama Cosmology Telescope (ACT) in Chile has traced the distribution of dark matter "on a quarter of the sky and across almost 14 billion years of time." From the report: In the image [here], the colored areas are the portions of the sky studied by the telescope. Orange regions show where there is more mass, or matter, along the line of sight; purple where there is less. Typical features are hundreds of millions of light-years across. The grey/white areas show where contaminating light from dust in our Milky Way galaxy has obscured a deeper view. The distribution of matter agrees very well with scientific predictions.

ACT observations indicate that the "lumpiness" of the Universe and the rate at which it has been expanding after 14 billion years of evolution are just what you'd expect from the standard model of cosmology, which has Einstein's theory of gravity (general relativity) at its foundation. Recent measurements that used an alternative background light, one emitted from stars in galaxies rather than the CMB, had suggested the Universe lacked sufficient lumpiness.

Another tension concerns the rate at which the Universe is expanding - a number called the Hubble constant. When [the European Space Agency's Planck observatory] looked at temperature fluctuations across the CMB, it determined the rate to be about 67 kilometres per second per megaparsec (A megaparsec is 3.26 million light-years). Or put another way - the expansion increases by 67km per second for every 3.26 million light-years we look further out into space. A tension arises because measurements of the expansion in the nearby Universe, made using the recession from us of variable stars, clocks in at about 73km/s per megaparsec. It's a difference that can't easily be explained. ACT, employing its lensing technique to nail down the expansion rate, outputs a number similar to Planck's. "It's very close - about 68km/s per megaparsec," said Dr Mathew Madhavacheril from the the University of Pennsylvania. ACT team-member Prof Blake Sherwin from Cambridge University, UK, added: "We and Planck and several other probes are coming in on the lower side. Obviously, you could have a scenario where both the measurements are right and there's some new physics that explains the discrepancy. But we're using independent techniques, and I think we're now starting to close the loophole where we could all be riding this new physics and one of the measurements has to be wrong."

Papers describing the new results have been submitted to The Astrophysical Journal and posted on the ACT website.

The New York Times added a new daily puzzle game to its library in the form of Digits. GameSpot reports: This collection of math conundrums tasks you with reaching a designated number by using six numbers that you're free to multiply, divide, subtract, or add up to reach the final result, so long as your process doesn't create any fractions or negative numbers.

Currently in beta and only available for this week, there'll be five of these math puzzles to solve every day. These aren't one-and-done puzzles like Wordle, and depending on the path you choose to solve one of these math mysteries, you'll be awarded 1-3 star ratings. If Digits proves to be popular with its readers, the New York Times will then start work on the further development of the game.

When Dr. Makenzie Lystrup was sworn in as the new director of NASA's Goddard Space Flight Center last week, she didn't take her oath of office on the Bible or the U.S. Constitution, but rather on a tome revered by space enthusiasts everywhere: Carl Sagan's Pale Blue Dot. From a report: The book, published in 1994, is named after an iconic image of Earth, snapped by the Voyager I probe, that depicts the planet as a small speck smothered by the emptiness of space. That photo inspired astronomer Carl Sagan to write: "Look again at that dot. That's here. That's home. That's us." For many, the book serves as a reminder of humanity's place in the universe and the need to preserve our home planet, which makes it similar to holy scripture for a newly appointed NASA director. On Thursday, when Lystrup chose to place her left hand on a copy of Sagan's book while being sworn in by NASA Administrator Bill Nelson, a photographer captured the moment, and NASA Goddard's social media shared the image. The constitution does not require that government officials be sworn in using a particular text, just that they "shall be bound by Oath or Affirmation, to support this Constitution." Most U.S. politicians and officials end up using the Bible.

schwit1 shares a report from Inverse: On March 23, sky observers marveled at a gorgeous display of northern and southern lights. It was a reminder that when our Sun gets active, it can spark a phenomenon called "space weather." Aurorae are among the most benign effects of this phenomenon. At the other end of the space weather spectrum are solar storms that can knock out satellites. The folks at Starlink found that out the hard way in February 2022. On January 29 that year, the Sun belched out a class M 1.1 flare and related coronal mass ejection. Material from the Sun traveled out on the solar wind and arrived at Earth a few days later. On February 3, Starlink launched a group of 49 satellites to an altitude only 130 miles above Earth's surface. They didn't last long, and now solar physicists know why.

A group of researchers from NASA Goddard Space Flight Center and the Catholic University of America took a closer look at the specifics of that storm. Their analysis identified a mass of plasma that impacted our planet's magnetosphere. The actual event was a halo coronal mass ejection from an active region in the northeast quadrant of the Sun. The material traveled out at around 690 kilometers per second as a shock-driving magnetic cloud. Think of it as a long ropy mass of material writhing its way through space. As it traveled, it expanded and at solar-facing satellites -- including STEREO-A, which took a direct hit from it -- made observations. Eventually, the cloud smacked into Earth's magnetosphere creating a geomagnetic storm.

The atmosphere thickened enough that it affected the newly launched Starlink stations. They started to experience atmospheric drag, which caused them to deorbit and burn up on the way down. It was an expensive lesson in space weather and provided people on Earth with a great view of what happens when satellites fall back to Earth. It was also that could have been avoided if they'd delayed their launch to account for the ongoing threat.

An anonymous reader quotes a report from ScienceAlert: Keeping enough qubits in their ideal state long enough for computations has so far proved a challenge. In a new experiment, scientists were able to keep a qubit in that state for twice as long as normal. Along the way, they demonstrated the practicality of quantum error correction (QEC), a process that keeps quantum information intact for longer by introducing room for redundancy and error removal. The idea of QEC has been around since the mid-90s, but it's now been shown to work in real time. Part of the reason for the experiment's success was the introduction of machine learning AI algorithms to tweak the error correction routine.

"For the first time, we have shown that making the system more redundant and actively detecting and correcting quantum errors provided a gain in the resilience of quantum information," says physicist Michel Devoret, from Yale University in Connecticut. [...] Like many quantum physics experiments, this one was run at ultra-cold temperatures -- a hundred times colder than outer space, in this case. The setup has to be carefully controlled in order to protect the qubit as much as possible. The error-corrected qubit lasted for 1.8 milliseconds -- only a blink as we might experience it, but an impressive span for a qubit operating on the quantum level. Now the research team will be able to refine the process further. "Our experiment shows that quantum error correction is a real practical tool," says Devoret. "It's more than just a proof-of-principle demonstration." In this case the breakthrough was down to several different factors, rather than one change. The QEC code was actually one from 2001, but improvements to it as well as upgrades to the quantum circuit fabrication process made a difference.

"Our experiment validates a cornerstone assumption of quantum computing, and this makes me very excited about the future of this field," says Volodymyr Sivak, a research scientist at Google and formerly at Yale University.

The research has been published in Nature.

"There's an invisible monster on the loose," NASA wrote on Thursday, "barreling through intergalactic space so fast that if it were in our solar system, it could travel from Earth to the Moon in 14 minutes. " This supermassive black hole, weighing as much as 20 million Suns, has left behind a never-before-seen 200,000-light-year-long "contrail" of newborn stars, twice the diameter of our Milky Way galaxy... Rather than gobbling up stars ahead of it, like a cosmic Pac-Man, the speedy black hole is plowing into gas in front of it to trigger new star formation along a narrow corridor. The black hole is streaking too fast to take time for a snack. Nothing like it has ever been seen before, but it was captured accidentally by NASA's Hubble Space Telescope. "We think we're seeing a wake behind the black hole where the gas cools and is able to form stars. So, we're looking at star formation trailing the black hole," said Pieter van Dokkum of Yale University in New Haven, Connecticut...

The trail must have lots of new stars, given that it is almost half as bright as the host galaxy it is linked to... Researchers believe gas is probably being shocked and heated from the motion of the black hole hitting the gas, or it could be radiation from an accretion disk around the black hole... Because it was so weird, van Dokkum and his team did follow-up spectroscopy with the W. M. Keck Observatories in Hawaii. He describes the star trail as "quite astonishing, very, very bright and very unusual." This led to the conclusion that he was looking at the aftermath of a black hole flying through a halo of gas surrounding the host galaxy.

This intergalactic skyrocket is likely the result of multiple collisions of supermassive black holes. Astronomers suspect the first two galaxies merged perhaps 50 million years ago. That brought together two supermassive black holes at their centers. They whirled around each other as a binary black hole. Then another galaxy came along with its own supermassive black hole. This follows the old idiom: "two's company and three's a crowd." The three black holes mixing it up led to a chaotic and unstable configuration. One of the black holes robbed momentum from the other two black holes and got thrown out of the host galaxy.

"The James Webb Space Telescope has captured a new stunning image of ice giant Uranus, with almost all its faint dusty rings on display," reports CNN: The image is representative of the telescope's significant sensitivity, NASA said, as the fainter rings have only been captured previously by the Voyager 2 spacecraft and the W.M. Keck Observatory on Maunakea in Hawaii. Uranus has 13 known rings, with 11 of them visible in the new Webb image. Nine rings are classified as the main rings, while the other two are harder to capture due to their dusty makeup and were not discovered until the Voyager 2 mission's flyby in 1986.

Two other, faint outer rings not shown in this latest image were discovered in 2007 from images taken by NASA's Hubble Space Telescope, and scientists hope Webb will capture them in the future.... "The JWST gives us the ability to look at both Uranus and Neptune in a completely new way because we have never had a telescope of this size that looks in the infrared," said Dr. Naomi Rowe-Gurney, a postdoctoral research scientist and solar system ambassador for the Webb space telescope at NASA Goddard Space Flight Center in Greenbelt, Maryland. "The infrared can show us new depths and features that are difficult to see from the ground with the atmosphere in the way and invisible to telescopes that look in visible light like Hubble."
"When Voyager 2 looked at Uranus, its camera showed an almost featureless blue-green ball in visible wavelengths," NASA explains. "With the infrared wavelengths and extra sensitivity of Webb we see more detail, showing how dynamic the atmosphere of Uranus really is." On the right side of the planet there's an area of brightening at the pole facing the Sun, known as a polar cap. This polar cap is unique to Uranus — it seems to appear when the pole enters direct sunlight in the summer and vanish in the fall; these Webb data will help scientists understand the currently mysterious mechanism. Webb revealed a surprising aspect of the polar cap: a subtle enhanced brightening at the center of the cap. The sensitivity and longer wavelengths of Webb's NIRCam may be why we can see this enhanced Uranus polar feature when it has not been seen as clearly with other powerful telescopes like the Hubble Space Telescope and Keck Observatory....

This was only a short, 12-minute exposure image of Uranus with just two filters. It is just the tip of the iceberg of what Webb can do when observing this mysterious planet.

The search for life beyond Earth "follows the water," reports the Economist (since water is vital for earth's lifeforms, and the laws of chemistry are universal). "For most of the space age that insight led scientists to Mars." But... More and more, though, planetary scientists are following the water to other places — and in particular to the so-called "icy moons" that orbit Jupiter, Saturn, Neptune and Uranus, the solar system's quartet of giant gas planets. Many of those moons are either known or suspected to have oceans beneath their icy shells, kept liquid by gravitational squeezing from the planets they orbit.

On April 13th, if all goes well, a new spacecraft will blast off from French Guiana en route to Jupiter with the aim of investigating some of those watery moons up close. The European Space Agency's Jupiter Icy Moons Explorer (given the slightly contrived acronym "JUICE ") will slingshot once around Venus and three times around Earth before arriving at Jupiter in 2031.... JUICE will investigate three of the so-called Galilean moons — Callisto, Europa and Ganymede, all of which are thought to have subsurface oceans. (The fourth, Io, is arid, and so not of interest.)

Ganymede is the probe's primary target. Despite being a moon, it is bigger than the planet Mercury. Its subsurface ocean may contain more water than all of Earth's oceans combined. The probe's cameras will add much more detail to the existing, low-resolution maps of Ganymede's surface. An ice-penetrating radar will scan several kilometres below the ground. A magnetometer will take advantage of the fact that Ganymede, apparently uniquely among the solar system's moons, has a weak magnetic field that interacts with the much bigger field generated by Jupiter itself. The subtleties of that magnetic field were an early clue for the existence of an ocean, hinting at the presence of a large chunk of conductive fluid — such as salty water — beneath the surface. Better readings of the magnetic field will help scientists estimate just how big the ocean is....

Nor is JUICE the only probe on its way to Jupiter. Next year NASA will launch Europa Clipper, focused, as its name suggests, on Europa. Despite its later launch, it will take a quicker route to Jupiter, arriving a few months before JUICE . And, because there are limits to what can be discerned from orbit, both NASA and the Europeans are sketching plans for future landers that would descend to the surface of such moons to sample the seawater directly.

SpaceX plans to carry out a launch rehearsal next week of Starship, the most powerful rocket ever built, and its first test flight possibly the following week, the private space company said Thursday. Phys.Org reports: SpaceX published photos of the massive Starship, which is designed to eventually send astronauts to the Moon and beyond, on its launchpad at the company's base in Texas. "Starship fully stacked at Starbase," SpaceX said in a tweet. "Team is working towards a launch rehearsal next week followed by Starship's first integrated flight test ~ week later pending regulatory approval."

SpaceX will need a green light from the Federal Aviation Administration before being allowed to carry out the orbital test launch. SpaceX conducted a successful test-firing of the 33 Raptor engines on the first-stage booster of Starship in February. The 230-foot (69-meter) Super Heavy booster was anchored to the ground during the test-firing, called a static fire, to prevent it from lifting off.

An anonymous reader quotes a report from the Guardian: Millions of lives could be saved by a groundbreaking set of new vaccines for a range of conditions including cancer, experts have said. A leading pharmaceutical firm said it is confident that jabs for cancer, cardiovascular and autoimmune diseases, and other conditions will be ready by 2030. Studies into these vaccinations are also showing "tremendous promise", with some researchers saying 15 years' worth of progress has been "unspooled" in 12 to 18 months thanks to the success of the Covid jab.

Dr Paul Burton, the chief medical officer of pharmaceutical company Moderna, said he believes the firm will be able to offer such treatments for "all sorts of disease areas" in as little as five years. The firm, which created a leading coronavirus vaccine, is developing cancer vaccines that target different tumor types. Burton said: "We will have that vaccine and it will be highly effective, and it will save many hundreds of thousands, if not millions of lives. I think we will be able to offer personalized cancer vaccines against multiple different tumor types to people around the world."

He also said that multiple respiratory infections could be covered by a single injection -- allowing vulnerable people to be protected against Covid, flu and respiratory syncytial virus (RSV) -- while mRNA therapies could be available for rare diseases for which there are currently no drugs. Therapies based on mRNA work by teaching cells how to make a protein that triggers the body's immune response against disease. Burton said :"I think we will have mRNA-based therapies for rare diseases that were previously undruggable, and I think that 10 years from now, we will be approaching a world where you truly can identify the genetic cause of a disease and, with relative simplicity, go and edit that out and repair it using mRNA-based technology." But scientists warn that the accelerated progress, which has surged "by an order of magnitude" in the past three years, will be wasted if a high level of investment is not maintained.

A NASA instrument to provide unprecedented resolution of monitoring major air pollutants -- down to four square miles -- lifted off on its way to geostationary orbit at 12:30 a.m. EDT Friday. The Tropospheric Emissions: Monitoring of Pollution (TEMPO) instrument will improve life on Earth by revolutionizing the way scientists observe air quality from space. From a report: "The TEMPO mission is about more than just studying pollution -- it's about improving life on Earth for all. By monitoring the effects of everything from rush-hour traffic to pollution from forest fires and volcanoes, NASA data will help improve air quality across North America and protect our planet," said NASA Administrator Bill Nelson. [...] From a fixed geostationary orbit above the equator, TEMPO will be the first space-based instrument to measure air quality over North America hourly during the daytime and at spatial regions of several square miles -- far better than existing limits of about 100 square miles in the U.S. TEMPO data will play an important role in the scientific analysis of pollution, including studies of rush hour pollution, the potential for improved air quality alerts, the effects of lightning on ozone, the movement of pollution from forest fires and volcanoes, and even the effects of fertilizer application.

TEMPO's observations will dramatically improve the scientific data record on air pollution -- including ozone, nitrogen oxide, sulfur dioxide and formaldehyde -- not only over the continental United States, but also Canada, Mexico, Cuba, the Bahamas, and part of the island of Hispaniola. "Our TEMPO slogan is 'It's about time,' which hints at TEMPO's ability to provide hourly air pollution data," said Xiong Liu, deputy principal investigator for TEMPO at the Center for Astrophysics, Harvard & Smithsonian in Cambridge, Massachusetts. "After working on the TEMPO for more than 10 years, it is about time to launch TEMPO to produce real TEMPO data and start the new era of air quality monitoring over North America."

China has invited Venezuela to join its lunar research station project as the country works to gain partners for the endeavor. SpaceNews reports: Venezuela would be the first country to join China and Russia in the International Lunar Research Station (ILRS), which is planned to be constructed in the early 2030s using super heavy-lift launch vehicles. The launches will follow smaller, precursor missions later this decade. Marglad Bencomo, executive director of the Bolivarian Agency for Space Activities (ABAE), visited China's new, national Deep Space Exploration Laboratory (DSEL) March 30 to discuss cooperation and exchanges. She was met by Wu Yanhua, former deputy director of the China National Space Administration (CNSA) and now executive vice chairman of DSEL. The two sides exchanged in-depth views on international cooperation in the field of deep space exploration, according to a DSEL statement.

Bencomo said that Venezuela was willing to sign a China-Venezuela Memorandum of Understanding as soon as possible to jointly promote the construction of international lunar research stations, according to the DSEL statement. ABAE has been invited to attend an international forum hosted by DSEL during China's national "space day," held annually on April 24 since 2016, potentially providing a platform for signing an MOU. China and Russia presented a roadmap for the joint ILRS in St. Petersburg, Russia, in 2021 and opened the project to interested parties.

An anonymous reader quotes a report from MIT Technology Review: Embryos made from stem cells -- instead of a sperm and egg -- have been created from monkey cells for the first time. When researchers put these "synthetic embryos" into the uteruses of adult monkeys, some showed the initial signs of pregnancy. It's the furthest scientists have ever been able to take lab-grown embryos in primates -- and the work hints that it may one day be possible to generate fetuses this way. The team behind the research, Zhen Liu at the Chinese Academy of Sciences in Shanghai and his colleagues, started with embryonic stem cells originally taken from macaque monkey embryos. These cells have been grown in labs for multiple generations and, given the right conditions, have the potential to develop into pretty much any type of body cell, including those that make up organs, blood, and nervous system.

The team used a set of lab conditions, which they tweaked and improved, to encourage embryonic stem cells to develop further. Over several days, the cells began developing in a very similar way to embryos. The resulting blobs of cells are called blastoids, because they look like early embryos, which are called blastocysts. After the blastoids had been growing in a dish for seven days, the researchers put them through a series of tests to figure out how similar they were to typical embryos. In one test, the team separated the individual cells in the blastoids and checked to see which genes were expressed in each one. The team analyzed over 6,000 individual cells this way.

These tests revealed close similarities between the stem-cell-derived embryos and conventional monkey embryos. Some of the blastoids were grown for longer -- up to 17 days. These structures looked very much like typical embryos, the researchers say, although other scientists not involved in the study say more evidence is needed to prove just how similar they are. The only way to find out how embryo-like these blastoids really are is to test whether they can develop in a monkey's uterus. So the team put between eight and 10 seven-day-old blastoids into the uteruses of each of eight adult monkeys. The researchers then monitored the transferred blastoids for three weeks. The researchers believe that in three of these monkeys, the blastoids successfully implanted in the uterus and appeared to generate a yolk sac -- one of the very first signs of pregnancy. These monkeys also had elevated levels of pregnancy hormones. In other words, they would have had a positive pregnancy test. But within 20 days of transfer, the monkey blastoids stopped developing and seemed to come apart, say Liu and colleagues, who published their results in the journal Cell Stem Cell. The results suggest that blastoids still aren't perfect replicas of normal embryos. "That might be because a typical embryo is generated from an egg, which is then fertilized by sperm," reports MIT Technology Review. "A blastoid made from stem cells might express genes in the same way as a normal embryo, but it may be missing something crucial that normally comes from an egg."

"There's also a chance that the team might have seen more progress if the experiment had been done in more monkeys. After all, of the 484 blastoids that were developing at day seven, only five survived to day 17."

In a new study, scientists found that it's possible for people to form false memories of an event within seconds of it occurring. This almost-immediate misremembering seems to be shaped by our expectations of what should happen, the team says. Gizmodo reports: "This study is unique in two ways, in our opinion. First, it explores memory for events that basically just happened, between 0.3 and 3 seconds ago. Intuitively, we would think that these memories are pretty reliable," lead author Marte Otten, a neuroscientist at the University of Amsterdam, told Gizmodo in an email. "As a second unique feature, we explicitly asked people whether they thought their memories are reliable -- so how confident are they about their response?" To do this, they recruited hundreds of volunteers over a series of four experiments to complete a task: They would look at certain letters and then be asked to recall one highlighted letter right after. However, the scientists used letters that were sometimes reversed in orientation, so the volunteers had to remember whether their selection was mirrored or not. They also focused on the volunteers who were highly confident about their choices during the task.

Overall, the participants regularly misremembered the letters, but in a specific way. People were generally good at remembering when a typical letter was shown, with their inaccuracy rates hovering around 10%. But they were substantially worse at remembering a mirrored letter, with inaccuracy rates up to 40% in some experiments. And, interestingly enough, their memory got worse the longer they had to wait before recalling it. When they were asked to recall what they saw a half second later, for instance, they were wrong less than 20% of the time, but when they were asked three seconds later, the rate rose as high as 30%.

According to Otten, the findings -- published Wednesday in PLOS One -- indicate that our memory starts being shaped almost immediately by our preconceptions. People expect to see a regular letter, and don't get easily fooled into misremembering a mirrored letter. But when the unexpected happens, we might often still default to our missed prediction. This bias doesn't seem to kick in instantaneously, though, since people's short-term memory was better when they had to be especially quick on their feet. "It is only when memory becomes less reliable through the passage of a tiny bit of time, or the addition of extra visual information, that internal expectations about the world start playing a role," Otten said.

Virgin Orbit, founded by Richard Branson, filed for Chapter 11 bankruptcy on Tuesday after the satellite launching business struggled to secure long-term funding following a failed launch in January. From a report: The filing comes less than two years after Virgin Orbit first went public at a valuation of roughly $3 billion. But the January mishap left the company scrambling for new funding and forced it to halt operations. "We believe that the Chapter 11 process represents the best path forward to identify and finalize an efficient and value-maximizing sale," Virgin Orbit Chief Executive Dan Hart said in a statement. The company, which was spun off from space tourism firm Virgin Galactic in 2017, sends satellites into orbit using rockets launched from a modified Boeing 747 plane. The Long Beach, California-based company lodged the filing seeking a sale of its assets in a Delaware court days after announcing the layoff of roughly 85% of its 750 employees. Virgin Orbit listed assets of about $243 million and total debt at $153.5 million as of Sept. 30. The company went public in December 2021 through a blank-check merger, raising $255 million less than expected.

One of mathematics' most intriguing visual mysteries has finally been solved -- thanks to a hobbyist in England. From a report: The conundrum: is there a shape that can be arranged in a tile formation, interlocking with itself ad infinitum, without the resulting pattern repeating over and over again? In nature and on our bathroom walls, we typically see tile patterns that repeat in "a very predictable, regular way," says Dr Craig Kaplan, an associate professor of computer science at the University of Waterloo in Ontario. What mathematicians were interested in were shapes that "guaranteed non-periodicity" -- in other words, there was no way to tile them so that the overall pattern created a repeating grid. Such a shape would be known as an aperiodic monotile, or "einstein" shape, meaning, in roughly translated German, "one shape" (and conveniently echoing the name of a certain theoretical physicist).

"There's been a thread of beautiful mathematics over the last 60 years or so searching for ever smaller sets of shapes that do this," Kaplan says. "The first example of an aperiodic set of shapes had over 20,000 shapes in it. And of course, mathematicians worked to get that number down over time. And the furthest we got was in the 1970s," when the Nobel-prize winning physicist Roger Penrose found pairs of shapes that fit the bill. Now, mathematicians appear to have found what they were looking for: a 13-sided shape they call "the hat." The discovery was largely the work of David Smith of the East Riding of Yorkshire, who had a longstanding interest in the question and investigated the problem using an online geometry platform. Once he'd found an intriguing shape, he told the New York Times, he would cut it out of cardstock and see how he could fit the first 32 pieces together. "I am quite persistent but I suppose I did have a bit of luck," Smith told the Guardian in an email.

Patients diagnosed with conditions like anxiety and sleep disorders have become caught in the crosshairs of America's opioid crisis, as secret policies mandated by a national opioid settlement have turned filling legitimate prescriptions into a major headache. Bloomberg reports: In July, limits went into effect that flag and sometimes block pharmacies' orders of controlled substances such as Adderall and Xanax when they exceed a certain threshold. The requirement stems from a 2021 settlement with the US's three largest drug distributors -- AmerisourceBergen Corp., Cardinal Health Inc. and McKesson Corp. But pharmacists said it curtails their ability to fill prescriptions for many different types of controlled substances -- not just opioids. Independent pharmacists said the rules force them come up with creative workarounds. Sometimes, they must send patients on frustrating journeys to find pharmacies that haven't yet exceeded their caps in order to buy prescribed medicines. It's unclear how the thresholds are impacting major chain pharmacies.

The Drug Enforcement Administration regulates the manufacturing, distribution and sale of controlled substances, which can be dangerous when used improperly. Drugmakers and wholesalers were always supposed to keep an eye out for suspicious purchases and have long had systems to catch, report and halt these orders. The prescription opioid crisis, enabled by irresponsible drug company marketing and prescribing, led to a slew of lawsuits and tighter regulations on many parts of the health system, including monitoring of suspicious orders. One major settlement required the three largest distributors to set thresholds on orders of controlled substances starting last July.

The "suspicious order" terminology is a bit of a misnomer, pharmacists said. The orders themselves aren't suspicious, it's just that the pharmacy has exceeded its limit for a specific drug over a certain time period. Any order that puts the pharmacy over its limit can be stopped. As a result, patients with legitimate prescriptions get caught up in the dragnet. Adding to the confusion, the limits themselves are secret. Drug wholesalers are barred by the settlement agreement from telling pharmacists what the thresholds are, how they're determined or when the pharmacy is getting close to hitting them. The exact limit for each pharmacy is kept secret in order to prevent pharmacists from gaming the system, according to Krista Tongring, leader of the DEA compliance practice at Guidepost Solutions and a former agency attorney. The purpose, she said, is to keep pharmacies from manipulating "their ordering patterns so as to get around the thresholds." According to a Cardinal Health document, limits are "calculated on a daily, monthly, and quarterly basis," reports Bloomberg. "But without more detailed information, it's impossible for pharmacists to predict when they are going to have to turn patients away."

"Pharmacies can request increases to their thresholds, but those take time to adjudicate, leaving patients scrambling to find their daily medicines elsewhere in the meantime."

An anonymous reader quotes a report from Motherboard: Scientists have discovered "unexpected physics" by opening up "slits" in time, a new study reports, achieving a longstanding dream that can help to probe the behavior of light and pioneer advanced optical technologies. The mind-boggling approach is a time-based variation on the famous double-slit experiment, first performed by Thomas Young in 1801, which opened a window into the weird probabilistic world of quantum mechanics by revealing the dual nature of light as both a particle and a wave. The new temporal version of this test offered a glimpse of the mysterious physics that occur at ultrafast timescales, which may inform the development of quantum computing systems, among other next-generation applications.

In the original version of the double-slit experiment, light passes through two slits that are spatially separated on an opaque screen. A detector on the other side of the screen records the pattern of the light waves that emerges from the slits. These experiments show that the light waves change direction and interfere with each other after going through the slits, demonstrating that light behaves as both a wave and particle. This insight is one of the most important milestones in our ongoing journey into the quantum world, and it has since been repeated with other entities, such as electrons, exposing the trippy phenomena that occurs at the small scales of atoms.

Now, scientists led by Romain Tirole, a PhD student studying nanophotonics at Imperial College London, have created a "temporal analogue of Young's slit experiment" by firing a beam of light at a special metamaterial called Indium Tin Oxide, according to a study published on Monday in Nature Physics. Metamaterials are artificial creations endowed with superpowers that are not found in nature. For instance, the Indium Tin Oxide used in the new study can change its properties in mere femtoseconds, a unit equal to a millionth of a billionth of a second. This incredible variability allows light waves to interact with the metamaterial at key moments in ultrafast succession, called "time slits," which produces a time-based diffraction pattern that is analogous to the results returned in the spatial version of the experiment. [...] In other words, the super-speedy changeability of Indium Tin Oxide finally made a time slit experiment possible, after many years of eluding scientists. To bring this vision to reality, Tirole and his colleagues used lasers to switch the reflectance of the material on and off at high speeds.