An anonymous reader shares a report: Shadows can do some adventurous, sometimes malignant, poetic things: They move, rebel, hide, refuse to be identified, vanish. All these visual aspects provide fertile ground for complex metaphors and narrations. Shadows are so visually telling that it takes little to move into emotionally tinged narratives. But it is the visual aspects that we primarily deal with here, with a special focus on several types of misrepresentations of shadows -- shadows doing impossible things -- that nevertheless reap a payoff for scene layout and do not look particularly shocking.

Painters have long struggled with the difficulties of depicting shadows, so much so that shadows -- after a brief, spectacular showcase in ancient Roman paintings and mosaics -- are almost absent from pictorial art up to the Renaissance and then are hardly present outside traditional Western art. Here, we embark on a journey that takes us through a number of extraordinary pictorial experiments -- some successful, some less so, but all interesting. We have singled out some broad categories of solutions to pictorial problems: depicted shadows having trouble negotiating obstacles in their path; shadow shapes and colors that stretch credibility; inconsistent illumination in the scene; and shadow character getting lost. We also find some taboos, that is, self-inflicted limitations on where or what to depict of a shadow. [...]

An anonymous reader shares a report: Heat pumps, in contrast, (to gas or oil furnaces) don't generate heat. They transfer it. That allows them to achieve more than 300 percent efficiency in some cases. Because they are more efficient, using heat pumps to cool and heat homes can help homeowners save money on their utility bills, said Sam Calisch, head of special projects at Rewiring America, a nonprofit advocacy group. In Maine, where heat pump adoption is growing, but where a majority of homes still burn oil, homeowners can save thousands of dollars in annual energy costs by making the switch, according to an analysis from Efficiency Maine, an independent administrator that runs the state's energy-saving programs.

Many heat pumps that are built for cold climates do have hefty upfront price tags. To soften the blow, a federal tax credit from last year's climate and tax law can cover 30 percent of the costs of purchase and installation, up to $2,000. As they've grown in popularity, heat pumps have increasingly been the subject of misconception and, at times, misinformation. Fossil-fuel industry groups have been the origin of many exaggerated and misleading claims, including the assertion that they don't work in regions with cold climates and are likely to fail in freezing weather.

While heat pumps do become less efficient in subzero temperatures, many models still operate close to normally in temperatures down to minus 13 degrees Fahrenheit, or minus 24 Celsius. Some of the latest models are even more efficient, and many "cold" countries, like Norway, Sweden and Finland, are increasingly embracing heat pumps. "We're starting to see evidence that the myth has been kept alive by people with an entrenched interest in avoiding the adoption of heat pumps," Dr. Calisch said. There are additional steps homeowners can take to make the most of their heat pumps, like sealing air leaks and drafts and improving insulation, said Troy Moon, the sustainability director for the city of Portland, Maine. Homeowners can also keep their existing furnaces as backup for the coldest days of the year, he said.

SpaceX is livestreaming coverage of its latest launch tonight. SpaceX and NASA were "preparing to launch a fresh crew to the International Space Station," reports CNN, "continuing the public-private effort to keep the orbiting laboratory fully staffed and return astronaut launches to U.S. soil

For this mission a reusable Falcon 9 rocket will eventually propel a Crew Dragon capsule into space — carrying six astronauts "from all over the world — two NASA astronauts, a Russian cosmonaut and an astronaut from the United Arab Emirates... to take over operations from the SpaceX Crew-5 astronauts who arrived at the space station in October 2022." They're expected to spend up to six months on board the orbiting laboratory, carrying out science experiments and maintaining the two-decade-old station.... During their stint in space, the Crew-6 astronauts will oversee more than 200 science-oriented projects, including researching how some substances burn in the microgravity environment and investigating microbial samples that will be collected from the exterior of the ISS.

They will play host to two other key missions that will stop by the ISS during their stay. The first is the Boeing Crew Flight Test, which will mark the first astronaut mission under a Boeing-NASA partnership. Slated for April, the flight will carry NASA astronauts Barry Wilmore and Sunita Williams to the space station, marking the last phase of a testing and demonstration program Boeing needs to carry out to certify its Starliner spacecraft for routine astronaut missions.

Then, in May, a group of four astronauts will arrive on a mission called AX-2 — a privately funded tourism mission to the space station. That mission, which will be carried out by a separate SpaceX Crew Dragon capsule, will include former NASA astronaut Peggy Whitson, now a private astronaut with the Texas-based space tourism company Axiom, which brokered and organized the mission. It will also include three paying customers, similar to the AX-1 mission that visited the ISS last year.
"It's another paradigm shift," mission commander Stephen Bowen said in January. "Those two events — huge events — in spaceflight happening during our increment, on top of all the other work we get to do, I don't think we're going to fully be able to absorb it until after the fact."

Roughly 25 hours after the launch the crew capsule willdock with the space station. This will be SpaceX's seventh astronaut-carrying flight for NASA since 2020.

Pennsylvania State University has an announcement. "Six massive galaxies discovered in the early universe are upending what scientists previously understood about the origins of galaxies in the universe." "These objects are way more massiveâ than anyone expected," said Joel Leja, assistant professor of astronomy and astrophysics at Penn State, who modeled light from these galaxies. "We expected only to find tiny, young, baby galaxies at this point in time, but we've discovered galaxies as mature as our own in what was previously understood to be the dawn of the universe."

Using the first dataset released from NASA's James Webb Space Telescope, the international team of scientists discovered objects as mature as the Milky Way when the universe was only 3% of its current age, about 500-700 million years after the Big Bang.... In a paper published February 22 in Nature, the researchers show evidence that the six galaxies are far more massive than anyone expected and call into question what scientists previously understood about galaxy formation at the very beginning of the universe. "The revelation that massive galaxy formation began extremely early in the history of the universe upends what many of us had thought was settled science," said Leja. "We've been informally calling these objects 'universe breakers' — and they have been living up to their name so far."

Leja explained that the galaxies the team discovered are so massive that they are in tension with 99% of models for cosmology. Accounting for such a high amount of mass would require either altering the models for cosmology or revising the scientific understanding of galaxy formation in the early universe — that galaxies started as small clouds of stars and dust that gradually grew larger over time. Either scenario requires a fundamental shift in our understanding of how the universe came to be, he added. "We looked into the very early universe for the first time and had no idea what we were going to find," Leja said. "It turns out we found something so unexpected it actually creates problems for science. It calls the whole picture of early galaxy formation into question."
"My first thought was we had made a mistake and we would just find it and move on with our lives," Leja says in the statement. "But we have yet to find that mistake, despite a lot of trying."

"While the data indicates they are likely galaxies, I think there is a real possibility that a few of these objects turn out to be obscured supermassive black holes. Regardless, the amount of mass we discovered means that the known mass in stars at this period of our universe is up to 100 times greater than we had previously thought. Even if we cut the sample in half, this is still an astounding change."

Phys.org got a more detailed explantion from one of the paper's co-authors: It took our home galaxy the entire life of the universe for all its stars to assemble. For this young galaxy to achieve the same growth in just 700 million years, it would have had to grow around 20 times faster than the Milky Way, said Labbe, a researcher at Australia's Swinburne University of Technology. For there to be such massive galaxies so soon after the Big Bang goes against the current cosmological model which represents science's best understanding of how the universe works. According to theory, galaxies grow slowly from very small beginnings at early times," Labbe said, adding that such galaxies were expected to be between 10 to 100 times smaller. But the size of these galaxies "really go off a cliff," he said....

The newly discovered galaxies could indicate that things sped up far faster in the early universe than previously thought, allowing stars to form "much more efficiently," said David Elbaz, an astrophysicist at the French Atomic Energy Commission not involved in the research. is could be linked to recent signs that the universe itself is expanding faster than we once believed, he added.

This subject sparks fierce debate among cosmologists, making this latest discovery "all the more exciting, because it is one more indication that the model is cracking," Elbaz said.

Three long-time Slashdot readers all submitted this story — schwit1, sinij, and DevNull127.

DevNull127 writes: Four U.S. agencies have concluded that the Covid-19 virus originated at the Wuhan market, the Wall Street Journal reports. The U.S. National Intelligence Council reached the same conclusion. Then there's two more agencies (including America's CIA) that are "undecided."

But there is one agency that decided — with "low confidence" — that the virus had somehow leaked from a lab. (And the FBI also decided with "moderate confidence" on that same theory.) "The new report highlights how different parts of the intelligence community have arrived at disparate judgments about the pandemic's origin," writes the Wall Street Journal — adding that unfortunately U.S. officials "declined" to give any details on what led to the Energy Department's position.
The Wall Street Journal also notes: Despite the agencies' differing analyses, the update reaffirmed an existing consensus between them that Covid-19 wasn't the result of a Chinese biological-weapons program, the people who have read the classified report said....

Some scientists argue that the virus probably emerged naturally and leapt from an animal to a human, the same pathway for outbreaks of previously unknown pathogens. Intelligence analysts who have supported that view give weight to "the precedent of past novel infectious disease outbreaks having zoonotic origins," the flourishing trade in a diverse set of animals that are susceptible to such infections, and their conclusion that Chinese officials didn't have foreknowledge of the virus, the 2021 report said.
Also responding to the Department of Energy's outlying position was a virologist at the Vaccine and Infectious Disease Organization at Canada's University of Saskatchewan, who posted a series of observations on Twitter: The available evidence shows overwhelmingly that the pandemic started at Huanan market via zoonosis. I have no idea what this evidence that Department of Energy has is. All I know that it is "weak" and resulted in a conclusion of "low confidence".

It reportedly comes from the DOE's own network of national labs rather than through spying. But I do know that to be consistent with the available scientific evidence, the DOE has to explain how the virus emerged twice over 2 wks in humans at the same market the size of a tennis court, over 8 km & across a river from the only lab in Wuhan working on SARSr-CoVs....

Claims of a progenitor at WIV are pure speculation & unsupported by evidence.... Despite 3 years of a global search for this evidence, it has not materialized, while evidence supporting zoonosis associated with Huanan has continued to stack up. At some point, an absence of evidence might just be evidence of absence.

America's Centers for Disease Control and Prevention "has issued a health advisory to warn the public of an increase of a drug-resistant bacteria called Shigella," reports CNN: There are limited antimicrobial treatments available for these particular drug-resistant strains of Shigella and it's also easily transmissible, warned the CDC in the Friday advisory. It's also able to spread antimicrobial resistance genes to other bacteria that infect the intestines.... The CDC says patients will recover from shigellosis without any antimicrobial treatment and it can be managed with oral hydration, but for those who are infected with the drug-resistant strains there are no recommendations for treatment if symptoms become more severe. The percentage of infections from drug-resistant strains of the bacteria increased from zero in 2015 to 5% in 2022, according to the CDC.

Nationwide, there are nearly 3 million antimicrobial-resistant infections each year, and more than 35,000 people die as a result, according to the CDC. A recent report by the United Nations said roughly 5 million deaths worldwide were associated with antimicrobial resistance in 2019 and the annual toll is expected to increase to 10 million by 2050 if steps are not taken to stop the spread of antimicrobial resistance.

In a keynote at FOSDEM 2023, NASA's science data officer Steve Crawford explored NASA's use of open-source software.

But LWN.net notes that the talk went far beyond just the calibration software for the James Webb Space Telescope and the Mars Ingenuity copter's flight-control framework. In his talk, Crawford presented NASA's Open-Source Science Initiative. Its goal is to support scientists to help them integrate open-science principles into the entire research workflow. Just a few weeks before Crawford's talk, NASA's Science Mission Directorate published its new policy on scientific information.

Crawford summarized this policy with "as open as possible, as restricted as necessary, always secure", and he made this more concrete: "Publications should be made openly available with no embargo period, including research data and software. Data should be released with a Creative Commons Zero license, and software with a commonly used permissive license, such as Apache, BSD, or MIT. The new policy also encourages using and contributing to open-source software." Crawford added that NASA's policies will be updated to make it clear that employees can contribute to open-source projects in their official capacity....

As part of its Open-Source Science Initiative, NASA has started its five-year Transform to Open Science (TOPS) mission. This is a $40-million mission to speed up adoption of open-science practices; it starts with the White House and all major US federal agencies, including NASA, declaring 2023 as the "Year of Open Science". One of NASA's strategic goals with TOPS is to enable five major scientific discoveries through open-science principles, Crawford said.
Interesting tidbit from the article: "In 2003 NASA created a license to enable the release of software by civil servants, the NASA Open Source Agreement. This license has been approved by the Open Source Initiative (OSI), but the Free Software Foundation doesn't consider it a free-software license because it does not allow changes to the code that come from third-party free-software projects."

Thanks to Slashdot reader guest reader for sharing the article!

Researchers at Linkoping, Lund and Gothenburg universities in Sweden have successfully grown electrodes in living tissue using the body's molecules as triggers. The result, published in the journal Science, paves the way for the formation of fully integrated electronic circuits in living organisms. Phys.Org reports: Linking electronics to biological tissue is important to understanding complex biological functions, combating diseases in the brain, and developing future interfaces between man and machine. However, conventional bioelectronics, developed in parallel with the semiconductor industry, have a fixed and static design that is difficult, if not impossible, to combine with living biological signal systems. To bridge this gap between biology and technology, researchers have developed a method for creating soft, substrate-free, electronically conductive materials in living tissue. By injecting a gel containing enzymes as the "assembly molecules," the researchers were able to grow electrodes in the tissue of zebrafish and medicinal leeches.

"Contact with the body's substances changes the structure of the gel and makes it electrically conductive, which it isn't before injection. Depending on the tissue, we can also adjust the composition of the gel to get the electrical process going," says Xenofon Strakosas, researcher at LOE and Lund University and one of the study's main authors. The body's endogenous molecules are enough to trigger the formation of electrodes. There is no need for genetic modification or external signals, such as light or electrical energy, which has been necessary in previous experiments. The Swedish researchers are the first in the world to succeed in this.

In their study, the researchers further show that the method can target the electronically conducting material to specific biological substructures and thereby create suitable interfaces for nerve stimulation. In the long term, the fabrication of fully integrated electronic circuits in living organisms may be possible. In experiments conducted at Lund University, the team successfully achieved electrode formation in the brain, heart, and tail fins of zebrafish and around the nervous tissue of medicinal leeches. The animals were not harmed by the injected gel and were otherwise not affected by the electrode formation. One of the many challenges in these trials was to take the animals' immune system into account.

An anonymous reader quotes a report from Ars Technica: Cheap, light, flexible, yet robust circuit boards are critical for wearable electronics, among other applications. In the future, those electronics might be printed on flexible circuits made out of bacterial cultures used to make the popular fermented black tea drink called kombucha, according to a recent paper posted to the arXiv preprint server. "Nowadays kombucha is emerging as a promising candidate to produce sustainable textiles to be used as eco-friendly bio wearables," co-author Andrew Adamatzky, of the University of the West of England in Bristol, old New Scientist. "We will see that dried -- and hopefully living -- kombucha mats will be incorporated in smart wearables that extend the functionality of clothes and gadgets. We propose to develop smart eco-wearables which are a convergence of dead and alive biological matter."

Adamatzky previously co-authored a 2021 paper demonstrating that living kombucha mats showed dynamic electrical activity and stimulating responses, as well as a paper last year describing the development of a bacterial reactive glove to serve as a living electronic sensing device. Inspired by the potential of kombucha mats for wearable electronics, he and his latest co-authors have now demonstrated that it's possible to print electronic circuits onto dried SCOBY mats. The team used commercially sourced kombucha bacteria to grow their mats, then air-dried the cultures on plastic or paper at room temperature. The mats don't tear easily and are not easily destroyed, even when immersed in water for several days. One of the test mats even survived oven temperatures up to 200 C (392 F), although the mats will burn when exposed to an open flame. Adamatzky et al. were able to print conductive polymer circuits onto the dried kombucha mats with an aerosol jet printer and also successfully tested an alternative method of 3D printing a circuit out of a conductive polyester/copper mix. They could even attach small LEDs to the circuits with an epoxy adhesive spiked with silver, which were still functioning after repeatedly being bent and stretched.

According to Adamatzky et al., unlike the living kombucha mats he worked with previously, the dried SCOBY mats are non-conductive, confining the electrical current to the printed circuit. The mats are also lighter, cheaper, and more flexible than the ceramic or plastic alternatives. Potential applications include wearable heart rate monitors, for instance, and other kombucha-based devices. "Future research will be concerned with printing advanced functional circuits, capable for detecting -- and maybe recognizing -- mechanical, optical, and chemical stimuli," the authors concluded.

Cars aren't the only conveyances being transformed by electricity. Along with electric motorcycles and snowmobiles, personal watercraft are floating better ways to coexist with nature and neighbors. This new breed of machines brings requisite thrills to the Great Outdoors, but without fouling the atmosphere or disturbing the peace with an internal-combustion racket. From a report: The latest comes from Florida-based Pelagion, whose founder and chief executive, engineer Jamie Schlinkmann, was inspired by childhood adventures on a watersports icon: A 1973 Kawasaki Jet Ski. Schlinkmann's machine, just the 213th ever built, is still one of his prized possessions. His company's Pelagion HydroBlade is an ingenious mash-up of classic stand-up Jet Skis and modern surfboard-style "eFoils." Those electric-powered boards had a real breakthrough in 2020 when Facebook founder Mark Zuckerberg was spotted sailing over Hawaiian waters on one model. The metaverse may spring to mind the first time you see an eFoil, with its rider seeming to fly above the waves on a magic carpet. Naturally, there's no magic, only hydrodynamics. Hydrofoils work like an airplane wing, only underwater: An aerodynamic wing creates high and low pressure areas as it slices through water, generating lift with precious little drag. Add an electric motor and propeller to create thrust and you've got a hydrofoil that doesn't require surf waves, a kite, or tow boat to generate power.

There's only one problem: Powered or not, a hydrofoil takes some practice and patience to learn to ride in a standing position, especially for people with no surfing or wakeboarding experience, or so-so balance skills. To solve that, Schlinkmann's invention adds a boom-mounted canard and rudder ahead of the rider to keep the craft airborne and steady without a rider having to constantly expend energy and adjust body position. Add a trusty set of handlebars, says Schlinkmann, and the HydroBlade handles more like a vehicle with which most of us are familiar: a bicycle. Making the experience somewhat like riding a bike, he says, helps ease the intimidation factor and boost appeal for people of all ages and abilities. [...] The design began to take shape around 2020. Schlinkmann pulled the engine and other ICE guts from his old Jet Ski and studied how he could make it electric. He realized a conventional electric Jet Ski might only have a 15- or 20-minute runtime on a single charge, which wasn't good enough. But after riding a few eFoils, the idea came together. For the HydroBlade, a pair of permanent-magnet radial-flux motors drive dual propellers at a peak 16 kilowatts (21 horsepower). They're fed by two battery packs, with a combined 600 cylindrical 2170 NCM cells and a total 11 kilowatt-hours of energy -- about eight to 10 times the capacity onboard a typical eFoil. A separate 1.6-kW charger can refill batteries in about 4 hours.

It is no mystery that a good night's sleep and a lie-in can improve your day. But researchers are suggesting that, far from just being enjoyable, quality sleep may even add years to people's lives. From a report: Men who regularly sleep well could live almost five years longer than those who do not, while women could benefit by two years, research suggests. And they could also enjoy better health during their lives. Researchers found that young people who had better sleep habits were less likely to die early. But the researchers said their findings indicated quantity of sleep was not in itself enough to achieve the possible health benefits -- quality of sleep is also important. Good sleep was based on five different factors: ideal sleep duration of seven to eight hours a night; difficulty falling asleep no more than two times a week; trouble staying asleep no more than two times a week; not using any sleep medication; and feeling well rested after waking up at least five days a week. The findings suggested that about 8% of deaths from any cause could be attributed to poor sleep patterns. The researchers included data from 172,321 people with an average age of 50, 54% of whom were women, who participated in the National Health Interview Survey between 2013 and 2018. The survey looked at the health of the US population and included questions about sleep and sleep habits.

MIT engineers are hoping to help doctors tailor treatments to patients' specific heart form and function, with a custom robotic heart. MIT News reports: The team has developed a procedure to 3D print a soft and flexible replica of a patient's heart. They can then control the replica's action to mimic that patient's blood-pumping ability. The procedure involves first converting medical images of a patient's heart into a three-dimensional computer model, which the researchers can then 3D print using a polymer-based ink. The result is a soft, flexible shell in the exact shape of the patient's own heart. The team can also use this approach to print a patient's aorta -- the major artery that carries blood out of the heart to the rest of the body.

To mimic the heart's pumping action, the team has fabricated sleeves similar to blood pressure cuffs that wrap around a printed heart and aorta. The underside of each sleeve resembles precisely patterned bubble wrap. When the sleeve is connected to a pneumatic system, researchers can tune the outflowing air to rhythmically inflate the sleeve's bubbles and contract the heart, mimicking its pumping action. The researchers can also inflate a separate sleeve surrounding a printed aorta to constrict the vessel. This constriction, they say, can be tuned to mimic aortic stenosis -- a condition in which the aortic valve narrows, causing the heart to work harder to force blood through the body.

Doctors commonly treat aortic stenosis by surgically implanting a synthetic valve designed to widen the aorta's natural valve. In the future, the team says that doctors could potentially use their new procedure to first print a patient's heart and aorta, then implant a variety of valves into the printed model to see which design results in the best function and fit for that particular patient. The heart replicas could also be used by research labs and the medical device industry as realistic platforms for testing therapies for various types of heart disease. The report has been published in the journal Science Robotics.

According to research published in the Journal of Experimental Biology, zebra fur is thinly striped and sharply outlined to thwart horsefly attacks. "These characteristics specifically eliminate the outline of large monochrome dark patches that are attractive to horseflies at close distances," adds Phys.Org. "The team theorizes that the thin back stripes serve to minimize the size of local features on a zebra that are appealing to the biting flies." From the report: The team found that tabanid horseflies are attracted to large dark objects in their environment but less to dark broken patterns. All-gray coats were associated with by far the most landings, followed by coats with large black triangles placed in different positions, then small checkerboard patterns in no particular order. In another experiment, they found contrasting stripes attracted few flies whereas more homogeneous stripes were more attractive. [...]

The team found little evidence for other issues that they tested, namely polarization or optical illusions confusing accurate landings such as the so-called "wagon-wheel effect" or "the barber-pole effect." Now the team want to determine why natural selection has driven striping in equids -- the horse family -- but not other hoofed animals.

An anonymous reader quotes a report from CNBC: Amazon on Wednesday said it had closed its $3.9 billion deal for primary care provider One Medical. Amazon agreed last July to acquire One Medical to deepen its presence in health care, and "dramatically improve" the experience of getting medical care. Amazon has long had ambitions to expand into health care, buying online pharmacy PillPack in 2018 for $750 million, then launching its own virtual clinic for chronic conditions, and prescription perks for Prime members. The deal gives Amazon access to One Medical's more than 200 brick-and-mortar medical offices in 26 markets, and roughly 815,000 members.

The purchase was the first major deal announced since CEO Andy Jassy took the helm from founder Jeff Bezos in July 2021, and Jassy has indicated he sees health care as a major area of expansion. In a statement, he said health care is ripe for disruption, citing long appointment times and the complexities of primary care. "Customers want and deserve better, and that's what One Medical has been working and innovating on for more than a decade," Jassy said in a statement. "Together, we believe we can make the health care experience easier, faster, more personal, and more convenient for everyone." Amazon said it would discount One Medical memberships for U.S. users to $144 from $199 for the first year, regardless of whether they're a Prime subscriber.

According to Bloomberg, Apple's quest to bring blood glucose monitoring to the Apple Watch is now at a "proof-of-concept stage." The last remaining hurdle is for it to be made smaller. Engadget reports: The technology, which uses lasers to gauge glucose concentration under the skin, was previously tabletop sized but has reportedly advanced to the point where an iPhone-sized wearable prototype is in the works. The system would not only help people with diabetes monitor their conditions, but would ideally alert people who are prediabetic, the insiders say. They could then make changes that prevent Type 2 (adult onset) diabetes.

The project has supposedly been in development for a long time. It began in 2010, when an ailing Steve Jobs had his company buy blood glucose monitoring startup RareLight. Apple is said to have kept the effort secret by operating it as a seemingly isolated firm, Avolonte Health, but folded it into a previously unknown Exploratory Design Group (XDG). CEO Tim Cook, Apple Watch hardware lead Eugene Kim and other top leaders have been involved.

Any real-world product is likely years away, according to Bloomberg. The industry also doesn't have a great track record of bringing no-prick monitors to market. In 2018, Alphabet's health subsidiary Verily scrapped plans for a smart contact lens that would have tracked glucose using tears. Even major brands with vast resources aren't guaranteed success, in other words, and it's not clear how accurate Apple's solution would be.

Images from NASA's Mars Reconnaissance Orbiter reveal that China's Zhurong rover remains stationary on the Red Planet as China remains silent on the status of its spacecraft. SpaceNews reports: The High Resolution Imaging Science Experiment (HiRISE) camera aboard the Mars Reconnaissance Orbiter (MRO) captured images of the rover on March 11, 2022, a second on Sept. 8, 2022 and finally Feb. 7, 2023. The images were published Feb. 21 by the HiRISE Operations Center The images show that the solar-powered Zhurong -- which landed in May 2021 -- has not moved since at least September 2022. It had entered a planned hibernation state in May 2022 to ride out the low solar radiation levels of winter in Mars's Utopia Planitia region.

Zhurong was expected to autonomously resume activities around December, around the time of Spring solstice in the northern hemisphere, when temperatures and light levels reached levels allowing the rover's battery and solar arrays to generate sufficient electrical power. However Chinese space authorities have not provided an update on the status of the rover. The South China Morning Post reported Jan. 7, citing sources that do not wish to be named, that the mission team was yet to receive a signal from Zhurong.

The progression of the HiRISE images suggest that Zhurong may have accumulated a covering of Martian dust on its surface. This could impact the function of both its solar arrays and the pair of "windows" which allow a chemical called n-undecane to store heat energy during the day and release it during the night. Zhurong does not carry a radioisotope heater unit -- which are used by the country's Yutu lunar rovers -- instead using systems including n-undecane for heating and a coating of aerogel for insulation.

An anonymous reader quotes a report from Ars Technica: As part of the state's biennial budget process, Texas Governor Greg Abbott has called on the state legislature to provide $350 million to create and fund a Texas Space Commission for the next two years. "With companies seeking to expand space travel in coming years, continued development of the space industry in the state will ensure Texas remains at the forefront not only in the United States, but the entire world," Abbott stated in his budget document for the 88th Legislature. "Further investment will cement Texas as the preeminent location for innovation and development in this rapidly growing industry. Due to increased competition from other states and internationally, further planning and coordination is needed to keep Texas at the cutting edge." Texas has a historic budget surplus this year due to oil prices, inflation, and other factors driving economic growth. The state is projected to have $188.2 billion available in general revenue for funding the business of the state over the 2024-2025 period, a surplus of $32.7 billion over spending during the previous two years.

In their initial drafts, both the House and the Senate budget bills for this legislative session include the full $350 million in funding for a space commission. The initiative is being led by the chair of the House Appropriations Committee, Texas Rep. Greg Bonnen, whose district just south of Houston is adjacent to NASA's Johnson Space Center. A source said the bill "has all of the support it needs to pass" from leaders in both the House and Senate. Bonnen's office did not specify what the Texas Space Commission will address, including how the money would be spent. A second source in the Texas Legislature told Ars that details about the commission's funding priorities were expected to be worked out later in the legislative session, which ends on May 29.

However, the framework for the proposed space commission appears to have been prepared by a Houston-based workforce-development organization called TexSpace, which published an annual report in December calling for the creation of such a commission. According to this document, the commission would "focus on policy and arranging statewide strategy by monitoring local, state, and federal policies and opportunities and establishing an economic ecosystem for Texas' space enterprises." It would include 15 members, including those appointed by political officials, as well as an appointee each from SpaceX and Blue Origin. [...] The commission will likely seek to ensure that SpaceX and Blue Origin continue to grow their presence in the state and to nurture other, smaller startups. "Compared to the Texas proposal, Space Florida has a modest annual budget of $12.5 million," notes Ars.

"Florida leaders made the brilliant decision to invest in the commercial space industry years ago, and that investment has paid off," Anna Alexopoulos Farrar, a vice president of communications for Space Florida, told Ars. "Space Florida alone had a $5.9 billion economic impact on the state over the past 15 years, and we project a $1.1 billion impact every year starting this year. It's not surprising that other states want to emulate our proven model, and we welcome the challenge from our friends in Texas -- competition yields the best outcomes for both businesses and taxpayers."

An anonymous reader quotes a report from Ars Technica: Two Republican lawmakers in Idaho have introduced a bill that would make it a misdemeanor for anyone in the state to administer mRNA-based vaccines -- namely the lifesaving and remarkably safe COVID-19 vaccines made by Pfizer-BioNTech and Moderna. If passed as written, it would also preemptively ban the use of countless other mRNA vaccines that are now in development, such as shots for RSV, a variety of cancers, HIV, flu, Nipah virus, and cystic fibrosis, among others. The bill is sponsored by Sen. Tammy Nichols of Middleton and Rep. Judy Boyle of Midvale, both staunch conservatives who say they stand for freedom and the right to life. But their bill, HB 154, proposes that "a person may not provide or administer a vaccine developed using messenger ribonucleic acid [mRNA] technology for use in an individual or any other mammal in this state." If passed into law, anyone administering lifesaving mRNA-based vaccines would be guilty of a misdemeanor, which could result in jail time and/or a fine.

While presenting the bill to the House Health & Welfare Committee last week, Nichols said their anti-mRNA stance stems from the fact that the COVID-19 vaccines were initially allowed under emergency use authorizations (EUAs) from the Food and Drug Administration, not the agency's full regulatory approval. "We have issues that this was fast-tracked," she told fellow lawmakers, according to reporting from local news outlet KXLY.com. [...] "They ultimately were approved under the ordinary approval process and did ultimately, you know, survive the scrutiny of being subjected to all the normal tests," Rep. Ilana Rubel, a democrat from Boise, said. Nichols seemed unswayed by the point, however, with KTVB7 reporting that she responded that the FDA's approval "may not have been done like we thought it should've been done."

To date, more than 269 million people in the US have received at least one COVID-19 vaccine, and over 700 million doses of mRNA-based vaccines have gone into American arms, according to data from the Centers for Disease Control and Prevention. The agency keeps close tabs on safety through various national surveillance systems. Although the shots do carry some risk (as is the case for any medical intervention), they have proven remarkably safe amid widespread use of hundreds of millions of doses in the US and worldwide. A study released late last year found that COVID-19 vaccination in the US alone averted more than 18 million additional hospitalizations and more than 3 million additional deaths from the pandemic coronavirus, SARS-CoV-2. The National Human Genome Research Institute notes that mRNA "is a type of single-stranded RNA involved in protein synthesis. mRNA is made from a DNA template during the process of transcription. The role of mRNA is to carry protein information from the DNA in a cell's nucleus to the cell's cytoplasm (watery interior), where the protein-making machinery reads the mRNA sequence and translates each three-base codon into its corresponding amino acid in a growing protein chain."

mRNA-based vaccines made their public debut amid the COVID-19 pandemic, but researchers have been "working toward these vaccines for decades beforehand," adds Ars.

Researchers are announcing that a 53-year-old man in Germany has been cured of HIV. From a report: Referred to as "the Dusseldorf patient" to protect his privacy, researchers said he is the fifth confirmed case of an HIV cure. Although the details of his successful treatment were first announced at a conference in 2019, researchers could not confirm he had been officially cured at that time. Today, researchers announced the Dusseldorf patient still has no detectable virus in his body, even after stopping his HIV medication four years ago. "It's really cure, and not just, you know, long term remission," said Dr. Bjorn-Erik Ole Jensen, who presented details of the case in a new publication in "Nature Medicine."

"This obviously positive symbol makes hope, but there's a lot of work to do," Jensen said. For most people, HIV is a lifelong infection, and the virus is never fully eradicated. Thanks to modern medication, people with HIV can live long and healthy lives. The Dusseldorf patient joins a small group of people who have been cured under extreme circumstances after a stem cell transplant, typically only performed in cancer patients who don't have any other options. A stem cell transplant is a high-risk procedure that effectively replaces a person's immune system. The primary goal is to cure someone's cancer, but the procedure has also led to an HIV cure in a handful of cases.

The Guardian reports: Scientists have pinpointed pieces of DNA which, they say, act like Bond villains in the way they help cancers spread. These microscopic agents have also been shown to be responsible for helping tumours gain resistance to anti-cancer drugs. The discovery of these bits of genetic material — known as extrachromosomal DNA or ecDNA — could revolutionise the treatments of some of the most aggressive tumours that affect people today, add the researchers....

Made up of tiny loops of DNA, these genetic villains survive outside the chromosomes which are our cells' main repositories of genetic material.... "We have found that ecDNA act as cancer-causing genes that have somehow separated themselves from a person's chromosomes and have started to behave in ways that circumvent the normal rules of genetics," said Stanford university geneticist Howard Chang. "They behave like villains in a Bond film. At first, in a film, you see different explosions, killings and disasters occurring and you don't know why they are happening or who is responsible. Then, at some point, you finally meet the villain who is revealed to be the agent of all this mayhem."
They also seem to resemble the Bond henchman who re-appears at the end of the movie. Professor Paul Mischel of California's Stanford University says that when treating the most aggressive cancers, "The vulnerable gene had quickly disappeared when threatened by cancer drugs and was hidden in ecDNA. Then it reappeared once it was safe for it to start causing damage again."

Mischel calls the discovery "a gamechanger," identifying the culprit "responsible for a large number of the more advanced, most serious cancers affecting people today. If we can block their activities, we can block the spread of these cancers."

And that hope was echoed by Dr Mariam Jamal-Hanjani of University College London Cancer Institute "The crucial point is that once we have found the cause of the problem then it becomes possible to develop and try out all sorts of drugs and therapies to tackle that." * "The discovery of how these bits of DNA behave inside our bodies is a gamechanger," said Professor Paul Mischel of California's Stanford university, one of the leaders of the programme. "We believe they are responsible for a large number of the more advanced, most serious cancers affecting people today. If we can block their activities, we can block the spread of these cancers."