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Medicine Science

Global Decline In Male Fertility Linked To Common Pesticides 144

An anonymous reader quotes a report from NBC News: A prolonged decline in male fertility in the form of sperm concentrations appears to be connected to the use of pesticides, according to a study published Wednesday. Researchers compiled, rated and reviewed the results of 25 studies of certain pesticides and male fertility and found that men who had been exposed to certain classes of pesticides had significantly lower sperm concentrations. The study, published Wednesday in Environmental Health Perspectives, included data from more than 1,700 men and spanned several decades. "No matter how we looked at the analysis and results, we saw a persistent association between increasing levels of insecticide and decreases in sperm concentration," said study author Melissa Perry, who is an environmental epidemiologist and the dean of the College of Public Health at George Mason University. "I would hope this study would get the attention of regulators seeking to make decisions to keep the public safe from inadvertent, unplanned impacts of insecticides." [...]

Scientists have long suspected changes to the environment could be contributing, and they've been probing the role of pesticides for decades in studies of animals and in human epidemiology research. The new analysis focuses on two groups of chemicals -- organophosphates and some carbamates -- that are commonly used in insecticides. The researchers looked at data collected from groups of people with exposures to pesticides and others who were not. Most, but not all, of the research centered on exposures in the workplace. The researchers controlled for outside factors that could contribute to lower sperm counts like smoking and age. Perry said researchers aren't sure how pesticides are affecting sperm concentrations and more research will be needed.

It's likely that pesticides are one of many environmental factors that could be contributing to a decline in sperm concentrations. The trend of sperm concentration declines has been widely observed in studies around the world, but it's a complicated topic and some scientists still have reservations. Sperm are notoriously difficult to count and the technology to do so has changed over the years. There are many confounding factors that can affect male fertility, including age, obesity and opioid use, to name a few. Sperm concentrations are one important data point to consider, but other factors -- like how sperm are shaped and how they swim -- are also critical to male fertility. Perry said she hopes agencies like the Environmental Protection Agency begin to factor the impact of chemicals and pesticides on reproductive health in their assessments. "Given the body of evidence and these consistent findings, it's time to proactively reduce these insecticide exposures for men wanting to have families," Perry said.
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Global Decline In Male Fertility Linked To Common Pesticides

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  • The male "Pill" in spray form.

  • by caseih ( 160668 ) on Wednesday November 15, 2023 @11:07PM (#64008801)

    Farmers and farm workers have a much higher exposure to pesticides than the general public. Is there a correlation there as well? One reason I ask is because in my area are a particular group of people who often work for farms in large numbers, and have an increased exposure as pesticides are handled and sprayed on farms. They also have relatively large families and have for years.

    • by Anonymous Coward on Thursday November 16, 2023 @12:17AM (#64008913)

      As far as I can see it's a non-problem. If you're still shooting millions of bullets it doesn't matter if half of them are duds. Furthermore as long as people are still reproducing after enough generations, the future generations could end up less sensitive to the pesticides (assuming it even applies enough selection pressure - if it doesn't, there's no problem).

      The population declines in many developed nations is mostly because people are choosing to not have children, not because they can't.

      I'd be more worried about cancer, congenital problems, Parkinson's and other neurological issues from pesticides.

      Anecdotal - I know someone whose kid used to have fits or something like that. Then they stopped having pest control come by regularly and their kid stopped getting fits. Maybe some pesticides are really OK for >90% of the population at the proper dose and usage, but peanuts are OK for >90% of the population too. Doesn't stop a minority from having big problems with the stuff.

      The other issue is some pesticides aren't as safe as the studies indicate because the studies only study the "active ingredient" not the "full recipe" or "inerts" which turn out to be not so inert and maybe even more toxic: https://www.scientificamerican... [scientificamerican.com]

      Until now, most health studies have focused on the safety of glyphosate, rather than the mixture of ingredients found in Roundup. But in the new study, scientists found that Roundup's inert ingredients amplified the toxic effect on human cells - even at concentrations much more diluted than those used on farms and lawns.

      One specific inert ingredient, polyethoxylated tallowamine, or POEA, was more deadly to human embryonic, placental and umbilical cord cells than the herbicide itself - a finding the researchers call "astonishing."

      "This clearly confirms that the [inert ingredients] in Roundup formulations are not inert,"

      • You should still be worried about people being infertile on a large scale regardless of the cause.

        • Why? What does the continuation of the human race have to do with the remainder of my life. This is like global warming. I won't be alive to see the results and now because of pesticides I can't have children. Seems like a win/win to me.

      • by serafean ( 4896143 ) on Thursday November 16, 2023 @04:48AM (#64009221)

        > As far as I can see it's a non-problem. If you're still shooting millions of bullets it doesn't matter if half of them are duds.

        a) It matters when you don't know what the cut-off number is.
        b) That's not what's happening. It's not just duds, it's the number of bullets (sperm count) has halved in the last 50 years, as well as the remaining sperm having reduced motility.

        Even if it doesn't yet affect babymaking too much, it should be treated as a symptom of something, and that something is worth finding. The other symptoms you mentioned might, or might not be linked.

      • by transporter_ii ( 986545 ) on Thursday November 16, 2023 @08:07AM (#64009423) Homepage

        I recommend you take the time to read this book: Count Down: How Our Modern World Is Threatening Sperm Counts, Altering Male and Female Reproductive Development, and Imperiling the Future of the Human Race, By: Shanna H. Swan,

        There are a lot of issues with falling sperm counts, even if there are still plenty of babies being born at the moment. For one, the children being born have health issues.

    • by AmiMoJo ( 196126 )

      The decline in fertility just reduces the odds of getting pregnant. If you have lots of unprotected sex, eventually you will have children in most cases.

    • While interesting not every system works on a linear response. It is entirely possible for it to somewhat linearly affect a system until some threshold is met, which could be quite a low dose, only for it to plateau and have little further effect. So someone eating only a bit of the affected products could have the same symptoms as someone chronically exposed to much higher levels. This is just generally true and may not apply to this article.
    • by ceoyoyo ( 59147 )

      It's a meta analysis (an analysis of the results of multiple other studies). If you take a look at the paper, table 2, you'll see what kind of conditions the different component studies looked at. The "biomonitoring" section is the strongest, that's where they actually measured how much pesticide exposure there was.

      There are study populations from insecticide manufacturing facilities, agricultural workplaces, etc.

  • I fail to see the downside to this. Kids are annoying* and far too often they're used as the justification for more government control which ultimately ends up affecting adults as well.

    * Yeah, parents out there in the peanut gallery, I know, you love your kids and they're the greatest thing ever. Some of us just aren't into the whole breeding thing, sorry.

    • If 'annoying' is why you don't want to be around kids, I fail to see the point in trying to explain any of these higher levels to you.

      I want to come out and personally thank you for letting us know your position on this.

      --
      Congratulations. - Yogi Berra

      • If 'annoying' is why you don't want to be around kids

        Ever been to Halloween Horror Nights at Universal? It would be so much more enjoyable if it was an 18+ event. Probably less profitable, but it would be way better without all the kids. Online gaming? Same deal, lose the kids and it would be better. Go out to dinner and someone's kid is screaming up a storm? Yeah, you know where I'm going with this.

        I have plenty of friends who have kids, so I know to some people being a parent truly does bring joy to their lives. Some of us are just fine without that

        • Go out to dinner and someone's kid is screaming up a storm

          It is unfair to blame the kid in this situation. They probably don't want to be there any more than you want them there.

    • You know you can move to live in a cave and there won't be anybody to annoy you?

    • Well, without kids (even other people's kids), all your retirement savings will be worth nothing. You'll need doctors, plumbers, delivery drivers, and they all will be retired if they are not kids now, or were kids in your adulthood.

  • by bloodhawk ( 813939 ) on Wednesday November 15, 2023 @11:24PM (#64008835)
    given our over population of the planet I wonder if this might not be a positive outcome.
    • by Arethan ( 223197 )

      Curious, what is your operating proof that the planet is overpopulated. Do you have reference data to share?

      • If you believe in things like co2 causing climate change then the world is over populated.

        If you don't then it's fine for now.

        • by Arethan ( 223197 )

          Seems plausible, but I was hoping to hear from the OP

        • What if you don't accept the proposition that co2 and population are somehow inextricably linked?

          • What if you don't accept the proposition that co2 and population are somehow inextricably linked?

            Carbon dioxide is put into the atmosphere by people using energy, so I'd say that the link between CO2 and population is pretty clear. Given no change in the way individual people use energy, more people will mean more carbon dioxide in the atmosphere.

            If we change the way we produce energy or the amount of energy we use, we could make less carbon dioxide per person. But even then, less carbon dioxide per person with a smaller population will mean less carbon dioxide, while less carbon dioxide per person wit

      • in percentages of biomass: 4% of all living mammals are wild. The remaining 96% are humans and their livestock.
        Farmed chickens account for almost 60% of all bird biomass, 30% are wild birds. The other 10% are whatever other birds we're farming.

      • Re:sounds good. (Score:4, Interesting)

        by dlarge6510 ( 10394451 ) on Thursday November 16, 2023 @05:20AM (#64009237)

        > Curious, what is your operating proof that the planet is overpopulated. Do you have reference data to share?

        Where have you been? This planet has been classed as overpopulated by practically anyone studying related subjects for the last 20 or more years.

        The metric? Water. Water is the scarce resource. Thats FRESH water mind, the stuff you drink, cook and wash with. There simply hasnt been enough for a long while and we have just been managing as it is. Going forward, access to fresh drinking water (and safe) will be increasinly an issue. Already with weather patern changes we have access issues in the south UK during summers, the resevoiurs just dry up in the south while the west of the country floods, which then just rus off into the sea and becomes useless for anyone.

        The UK's aquifers have shown a net drop in supply year on year for a long time now, just not enough rain and too high a demand equals a deficit. When it does rain, it hammers it down and thus like already mentioned just floods homes and runs into the sea, leaving just a little to top up the aquifers for next year.

        LAst winter for example it barely rained in the south UK at all. Plenty of dull cloud, for weeks on end but no rain or snow for months and so we actually had droughts in winter would you believe!

        You might think that there is plenty of space in rural France, the USA etc? But ask yourself: Why is there nobody there already? Why didnt settlements get built hundreds of years ago already? Why is it mostly empty? Well, food and water. Where there is water and no people, there are farms, needed to export food to countries like the UK that cant sustain itself on its own green pastures (UK has been over populated for decades). Where there is no water, just that which falls from the sky, well again nobody would build a settlement there. Villages are built next to or on a water course.

        • So your real problem isn't lack of rain but your government's obviously lack of interest in capturing enough to sustain your population. As you mention, you let a large portion of it just run off into the ocean. California has the same problems.

          There is plenty of water if both our societies could be bothered to invest in water catchments and a bit of engineering things to be more sustainable. We already have the technology but naturally it would cost our water companies money so screw that.

          I do agree we are

      • by gweihir ( 88907 )

        Minimal working mental abilities. You obviously lack those.

      • It depends on what you set to be the energy requirements per person against what we can generate sustainably. For an American style life, we're overpopulated (e.g. the old canard of 'you could give each family an acre in Texas!' doesn't work), for a rural poor person in Asia we wouldn't be, but they're lacking in the joy of posting to Slashdot, so is that really living?
  • by thesjaakspoiler ( 4782965 ) on Wednesday November 15, 2023 @11:30PM (#64008845)

    My balls were not Round-Up Ready (tm)(r)(c).

  • How much influence does it have? 1% as much influence as the subject being obese? Or maybe even 2%?

  • Are mice different "down there"? Why didn't high-dose mice tests catch this?

  • by gweihir ( 88907 ) on Thursday November 16, 2023 @08:25AM (#64009457)

    Who would have expected that ...

  • Would it be impossible to imagine that gender dysphoria is linked to man-made chemicals I wonder?
    • For sure, you'd expect a certain amount anyhow in a wild-type environment but that sort of thing is currently implicated in trends that don't otherwise seem linked to merely baseline nutrition like increasing bust size in Asia. Epigenetic effects can even make someone XY biologically female in rare cases, certainly in between states could be caused by various pollutants.
    • I have wondered this as well, but have no data, in part because it's almost impossible to separate social factors from this, too.
    • While the name is new the condition isn't, so any link would be with incident rates and not the existence itself.

      There are also social factors that will have raised reporting rates, making teasing out any really solid data is a statistical challenge.

  • by TJHook3r ( 4699685 ) on Thursday November 16, 2023 @09:25AM (#64009575)
    It's in the name people, it prevents pests!

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