An anonymous reader quotes a report from The Guardian: A severely paralyzed woman has been able to speak through an avatar using technology that translated her brain signals into speech and facial expressions. The latest technology uses tiny electrodes implanted on the surface of the brain to detect electrical activity in the part of the brain that controls speech and face movements. These signals are translated directly into a digital avatar's speech and facial expressions including smiling, frowning or surprise. The patient, a 47-year-old woman, Ann, has been severely paralyzed since suffering a brainstem stroke more than 18 years ago. She cannot speak or type and normally communicates using movement-tracking technology that allows her to slowly select letters at up to 14 words a minute. She hopes the avatar technology could enable her to work as a counsellor in future.

The team implanted a paper-thin rectangle of 253 electrodes on to the surface of Ann's brain over a region critical for speech. The electrodes intercepted the brain signals that, if not for the stroke, would have controlled muscles in her tongue, jaw, larynx and face. After implantation, Ann worked with the team to train the system's AI algorithm to detect her unique brain signals for various speech sounds by repeating different phrases repeatedly. The computer learned 39 distinctive sounds and a Chat GPT-style language model was used to translate the signals into intelligible sentences. This was then used to control an avatar with a voice personalized to sound like Ann's voice before the injury, based on a recording of her speaking at her wedding.

The technology was not perfect, decoding words incorrectly 28% of the time in a test run involving more than 500 phrases, and it generated brain-to-text at a rate of 78 words a minute, compared with the 110-150 words typically spoken in natural conversation. However, scientists said the latest advances in accuracy, speed and sophistication suggest the technology is now at a point of being practically useful for patients. A crucial next step is to create a wireless version of the BCI that could be implanted beneath the skull. The findings have been published in the journal Nature.

India has become the first country to land a spacecraft on the moon's south pole. It launched Chandrayaan-3 in mid-July, with the spacecraft entering the moon's orbit on Aug. 5. Earlier this week, Russia crashed its Luna-25 rocket in the same lunar region. From a report: It's notoriously difficult to land a rover on the moon. Russia's Luna-25 crashed while making an attempt just this week, while Japanese company ispace failed to land an unmanned lander in April.â 1 Since the moon has no atmosphere, landers can't just softly touch down on the lunar surface. And, without GPS capabilities, scientists rely on the lander's computers to accurately identify where the spacecraft will touch down. India is only the fourth country to pull off a moon landing, behind the U.S., China, and Russia. The nation's lunar aspirations are part of a push by Prime Minister Narendra Modi to garner investments for private space exploration and satellite launches. Speaking at the rocket's launch in July, Modi heralded a "new chapter" in India's space program.

A two-year human trial conducted by James Cook University (JCU) has concluded, demonstrating positive results using low-dose human hookworm therapy to treat chronic conditions, particularly in relation to type 2 diabetes. New Atlas reports: [O]f the 24 participants who received worms, when offered a dewormer at the end of the second year of the trial, with the option to stay in the study for another 12 months, only one person chose to kill off their gut buddies -- and it was only because they had an impending planned medical procedure. "All trial participants had risk factors for developing cardiovascular disease and type 2 diabetes," said Dr Doris Pierce, from JCU's Australian Institute of Tropical Health and Medicine (AITHM). "The trial delivered some considerable metabolic benefits to the hookworm-treated recipients, particularly those infected with 20 larvae."

In this double-blinded trial, 40 participants aged 27 to 50, with early signs of metabolic diseases, took part. They received either 20 or 40 microscopic larvae of the human hookworm species Necator americanus; another group took a placebo. As an intestinal parasite, the best survival skill is to keep the host healthy, which will provide a long-term stable home with nutrients 'on tap.' In return, these hookworms pay the rent in the form of creating an environment that suppresses inflammation and other adverse conditions that can upset that stable home. While the small, round worms can live for a decade, they don't multiply unless outside the body, and good hygiene means transmission risk is very low.

As for the results, those with 20 hookworms saw a Homeostatic Model Assessment of Insulin Resistance (HOMA-IR) level drop from 3.0 units to 1.8 units within the first year, which restored their insulin resistance to a healthy range. The cohort with 40 hookworms still experienced a drop, from 2.4 to 2.0. Those who received the placebo saw their HOMA-IR levels increase from 2.2 to 2.9 during the same time frame. "These lowered HOMA-IR values indicated that people were experiencing considerable improvements in insulin sensitivity -- results that were both clinically and statistically significant," said Dr Pierce. Those with worms also had higher levels of cytokines, which play a vital role in triggering immune responses. The study was published in the journal Nature Communications.

An anonymous reader quotes a report from The Guardian: Methane is a potent greenhouse gas emitted from energy (natural gas and petroleum systems), industry, agriculture, land use and waste management activities. Now a group of researchers from California University Long Beach are proposing a method of removing methane by using a group of bacteria known as methanotrophs to naturally convert methane to carbon dioxide and biomass. All the bacteria in this group "'eat' methane, removing it from air and converting part of it to cells as a source of sustainable protein," according to the lead researcher, Mary E Lidstrom. Lidstrom's team have found a strain of bacteria within this group called methylotuvimicrobium buryatense 5GB1C that can remove methane efficiently even when it is present in lower amounts. If it became widespread, the technology has the potential to help slow global heating, the researchers said.

Typically, this group of bacteria thrive in environments with high levels of methane (between 5,000 and 10,000 parts per million (ppm)). The normal concentrations in our atmosphere have much lower levels of only about 1.9 ppm of methane. But certain areas such as landfills, rice fields and oilwells emit higher concentrations of about 500 ppm. "Bacteria that rapidly eat methane at the higher concentrations found around cattle herds, etc could make a huge contribution to cutting methane emissions, especially from tropical agriculture," said Euan Nisbet, professor of Earth sciences at Royal Holloway, University of London, commenting on the findings of the study.

The strain's high methane consumption rate is probably due to a low energy requirement and greater attraction for methane – more than five times more than that of other bacteria, according to the study. "The bacteria oxidise the methane to CO2 (a much less powerful greenhouse gas) and so you can even use the exhaust to pump into greenhouses and grow tomatoes," said Nisbet. "The biggest barrier to implementation now is technical: we need to increase the methane treatment unit 20-fold. If we can achieve that, then the biggest barriers become investment capital and public acceptance. We believe we could have field pilots tested within three to four years, and scale up would then depend on investment capital and commercialization," said Lidstrom. The study has been published in the journal Proceedings of the National Academy of Sciences (PNAS).

A piece of space debris being monitored by the European Space Agency as part of a mission to remove trash from space was hit by another piece of debris, splintering the object into more pieces. From a report: ESA confirmed Tuesday that the US's 18th Space Defense Squadron, which tracks objects in orbit, spotted a number of new pieces in the vicinity of a payload adapter named VESPA that the agency had planned to pluck from space. The most likely cause of those new fragments is "the hypervelocity impact of a small, untracked object" ramming into VESPA, according to ESA. VESPA was left over from the launch of a European Vega rocket that took off from South America in 2013. It was part of a cone-shaped attachment used to deploy the rocket's satellite into orbit, and has been in Earth's orbit ever since. ESA said its new fragments don't pose much of a risk to any other spacecraft at the moment.

Once tooth decay has set in, all a dentist can do is fill the gap with an artificial plug -- a filling. But in a paper published in Cell, Hannele Ruohola-Baker, a stem-cell biologist at the University of Washington, and her colleagues offer a possible alternative. Economist: Stem cells are those that have the capacity to turn themselves into any other type of cell in the body. It may soon be possible, the researchers argue, to use those protean cells to regrow a tooth's enamel naturally. The first step was to work out exactly how enamel is produced. That is tricky, because enamel-making cells, known as ameloblasts, disappear soon after a person's adult teeth have finished growing. To get round that problem, the researchers turned to samples of tissue from human foetuses that had been aborted, either medically or naturally. Such tissues contain plenty of functioning ameloblasts. The researchers then checked to see which genes were especially active in the enamel-producing cells. Tooth enamel is made mostly of calcium phosphate, and genes that code for proteins designed to bind to calcium were particularly busy. They also assessed another type of cell called odontoblasts. These express genes that produce dentine, another type of hard tissue that lies beneath the outer enamel. Armed with that information, Dr Ruohola-Baker and her colleagues next checked to see whether the stem cells could be persuaded to transform into ameloblasts.

The team devised a cocktail of drugs designed to activate the genes that they knew were expressed in functioning ameloblasts. That did the trick, with the engineered ameloblasts turning out the same proteins as the natural sort. A different cocktail pushed the stem cells to become odontoblasts instead. Culturing the cells together produced what researchers call an organoid -- a glob of tissue in a petri dish which mimics a biological organ. The organoids happily churned out the chemical components of enamel. Having both cell types seemed to be crucial: when odontoblasts were present alongside ameloblasts, genes coding for enamel proteins were more strongly expressed than with ameloblasts alone. For now, the work is more a proof of concept than a prototype of an imminent medical treatment. The next step, says Dr Ruohola-Baker, is to try to boost enamel production even further, with a view to eventually beginning clinical trials. The hope is that, one day, medical versions of the team's organoids could be used as biological implants, to regenerate a patient's decayed teeth.

Under a new initiative, named Bandwagon, SpaceX is expanding its rideshare program to cater to the demand for launches to mid-inclination orbits. TechCrunch reports: Orbital inclination refers to what part of the Earth is visible to a satellite as it rotates around the planet. A satellite in an equatorial orbit is at 0 degrees inclination; a satellite in a sun-synchronous orbit (SSO) is slightly higher than 90 degrees; and a mid-inclination orbit is around 45 degrees. Currently, SpaceX offers rideshare services on the Falcon 9 rocket to SSO through the Transporter program, which is in notoriously high demand. But mid-inclination orbits (MIOs) are appealing to a growing number of customers, especially to remote sensing companies that want to strengthen their coverage over areas like parts of Asia and the Middle East. Right now, companies must often purchase a dedicated launch from Rocket Lab if they want to position a satellite in MIO.

With the new rideshare program, called Bandwagon, SpaceX is going after this slice of the market. According to SpaceX's website, it currently has two Bandwagon missions booked for 2024 and two for 2025. If they become even close to the popularity of the Rideshare program, they could be a major threat to all other small launch providers: According to Jarrod McLachlan, director of rideshare sales at SpaceX, who spoke at the industry conference, SpaceX has delivered 682 spacecraft to orbit to date via rideshare missions.

The rapid rise of generative AI has stoked anxieties across disciplines. High school teachers and college professors are worried about the potential for cheating. News organizations have been caught with shoddy articles penned by AI. And now, peer-reviewed academic journals are grappling with submissions in which the authors may have used generative AI to write outlines, drafts, or even entire papers, but failed to make the AI use clear. Wired: Journals are taking a patchwork approach to the problem. The JAMA Network, which includes titles published by the American Medical Association, prohibits listing artificial intelligence generators as authors and requires disclosure of their use. The family of journals produced by Science does not allow text, figures, images, or data generated by AI to be used without editors' permission. PLOS ONE requires anyone who uses AI to detail what tool they used, how they used it, and ways they evaluated the validity of the generated information. Nature has banned images and videos that are generated by AI, and it requires the use of language models to be disclosed. Many journals' policies make authors responsible for the validity of any information generated by AI.

Experts say there's a balance to strike in the academic world when using generative AI -- it could make the writing process more efficient and help researchers more clearly convey their findings. But the tech -- when used in many kinds of writing -- has also dropped fake references into its responses, made things up, and reiterated sexist and racist content from the internet, all of which would be problematic if included in published scientific writing. If researchers use these generated responses in their work without strict vetting or disclosure, they raise major credibility issues. Not disclosing use of AI would mean authors are passing off generative AI content as their own, which could be considered plagiarism. They could also potentially be spreading AI's hallucinations, or its uncanny ability to make things up and state them as fact.

LiveScience brings an update on China's Chang'e-4 — the first spacecraft to ever land on the far side of the moon.

Its Lunar Penetrating Radar has now mapped the lunar subsurface "in finer detail than ever before" by bouncing radio signals deep underground: Their results, which were published Aug. 7 in the Journal of Geophysical Research: Planets, reveal billions of years of previously hidden lunar history. These new data suggest the top 130 feet of the lunar surface are made up of multiple layers of dust, soil, and broken rocks, said lead study author Jianqing Feng, an astrogeological researcher at the Planetary Science Institute in Tucson, Arizona... Farther down, the scientists discovered five distinct layers of lunar lava that seeped across the landscape billions of years ago.

Scientists think our moon formed 4.51 billion years ago, not long after the solar system itself, when a Mars-size object slammed into Earth and broke off a chunk of our planet The moon then continued to be bombarded by objects from space for roughly 200 million years. Some impacts cracked the moon's surface. Like Earth, the moon's mantle at that time contained pockets of molten material called magma, which seeped out through the newly formed cracks in a series of volcanic eruptions, Feng said.

The new data from Chang'e-4 shows that process slowing down over time: Feng and his colleagues found that the layers of volcanic rock grew thinner the closer they were to the moon's surface. This suggests that less lava flowed in later eruptions compared with earlier ones. "[The moon] was slowly cooling down and running out of steam in its later volcanic stage," Feng said. "Its energy became weak over time...."

However, there could still be magma deep underneath the lunar surface, Feng said.

"Russia's first lunar mission in decades has ended in failure with its Luna 25 spacecraft crashing into the moon's surface," reports CNN: The incident, a blow to Russia's space ambitions, happened after communication with the robotic spacecraft was interrupted, a blow to Russia's space ambitions. Russia's space agency, Roscosmos, said it lost touch with Luna 25 on Saturday around 2:57 p.m. Moscow time... According to a "preliminary analysis," Luna-25 "switched to an off-design orbit" before the collision, Roscosmos said. It was not immediately clear what caused the crash... The news comes a day after the spacecraft reported an "emergency situation" as it was trying to enter a pre-landing orbit, according to Roscosmos...

The spacecraft was meant to complete Russia's first lunar landing mission in 47 years. The country's last lunar lander, Luna 24, landed on the surface of the moon on August 18, 1976... Luna 25 was seen as a proving ground for future robotic lunar exploration missions by Roscosmos. Several future Luna spacecraft were slated to make use of the same design. If it had been successful, Luna 25 would have marked a huge stride for the country's civil space program — which some experts say has faced issues for decades — and demonstrate that it could still perform in high-profile, high-stakes missions. "They were having a lot of problems with quality control, corruption, with funding," said Victoria Samson, the Washington office director for Secure World Foundation, a nonprofit that promotes the peaceful exploration of outer space, during an interview Friday.

News that Russia experienced issues with its spacecraft elicited sympathy that reverberated throughout the space community. Thomas Zurbuchen, NASA's former head of science, said in a social media post that no one in the industry "wishes bad onto other explorers... We are reminded that landing on any celestial object is anything but easy & straightforward," he said,
Thanks to long-time Slashdot reader Baron_Yam and TheNameOfNick for sharing the news.

An anonymous reader quotes a report from The Guardian: In May, the World Health Organization issued an alarming report that declared widely used non-sugar sweeteners like aspartame are likely ineffective for weight loss, and long term consumption may increase the risk of diabetes, cardiovascular diseases and mortality in adults. A few months later, WHO declared aspartame, a key ingredient in Diet Coke, to be a "possible carcinogen," then quickly issued a third report that seemed to contradict its previous findings -- people could continue consuming the product at levels determined to be safe decades ago, before new science cited by WHO raised health concerns. That contradiction stems from beverage industry corruption of the review process by consultants tied to an alleged Coca-Cola front group, the public health advocacy group US Right-To-Know said in a recent report.

It uncovered eight WHO panelists involved with assessing safe levels of aspartame consumption who are beverage industry consultants who currently or previously worked with the alleged Coke front group, International Life Sciences Institute (Ilsi). Their involvement in developing intake guidelines represents "an obvious conflict of interest", said Gary Ruskin, US Right-To-Know's executive director. "Because of this conflict of interest, [the daily intake] conclusions about aspartame are not credible, and the public should not rely on them," he added. [...] Ilsi describes itself as a nonprofit that conducts "science for the public good", but it was founded in 1978 by a Coca-Cola executive who simultaneously worked for the company through 2021, US Right-To-Know found. Other Coca-Cola executives have worked with the group, and US Right-To-Know detailed tax returns that show millions in donations from Coca-Cola and other beverage industry players. Coke ended its official membership with the group in 2021.

Over the years, Ilsi representatives have sought to shape food policy worldwide, and Ruskin, who has written multiple peer-reviewed papers on the group, characterized the aspartame controversy as a "masterpiece in how Ilsi worms its way into these regulatory processes." US Right To Know identified six out of 13 Jefca panel members with ties to the industry group. After it released its report, the WHO acknowledged two more of its members with industry ties. In a statement to the Guardian, a WHO spokesperson defended the industry consultants' inclusion in the review process. "For the meeting on aspartame, Jefca selected the experts likely to make the best contributions to the debate," said spokesperson Fadela Chaib. She said WHO's guidelines only require disclosure of conflicts of interest within the last four years. "To our knowledge, the experts you listed by name have not participated in any Ilsi activities for at least 10 years," she said. But that partially contradicts a statement made by WHO just weeks before to the news outlet Le Parisien in which it acknowledged two people currently working with Ilsi were involved in the process. The Guardian had also asked about those two people identified in the Parisien story but were not listed "by name" in its email. The WHO told Le Parisien: "We regret that this interest was not declared by these two experts either in the written statement or orally at the opening of the meeting."

According to a new study of studies, researchers have concluded that blue light-filtering eyeglasses might not deliver on claims made by advertisers or optometrist offices. NewAtlas reports: To reach their conclusion, researchers at the University of Melbourne with colleagues from Monash University, and City, University of London looked at 17 published studies from six different countries relating to the use of eyeglasses that block blue light. The randomized control studies ranged in size from five to 156 participants and each took place over a time period of just less than one day to five weeks. They found that based on the current research, nothing conclusive could be said about the benefits of blue-light-blocking glasses on overall eye health, sleep quality, or visual performance. This is despite the facts that there are a range of advertising claims regarding these very benefits, and that such lenses are often prescribed for patients based on their alleged efficacy.

Downie and her team are quick to point out that even with such a comprehensive review of the current research on blue-blocking glasses, it would take a much larger study to reach truly valuable data about the use of such specs. One of the issues they point out is that none of the studies reviewed had long enough follow-up periods for the researchers to make conclusions about the long-term use of the glasses. Singh also points out that even without larger, longer, and more rigorous studies, the efficacy of blue-light-blocking glasses remains dubious. "The amount of blue light our eyes receive from artificial sources, such as computer screens, is about a thousandth of what we get from natural daylight," he said. "It's also worth bearing in mind that blue-light filtering lenses typically filter out about 10-25% of blue light, depending on the specific product. Filtering out higher levels of blue light would require the lenses to have an obvious amber tint, which would have a substantial effect on color perception." The new study has been published in the Cochrane Database of Systematic Reviews.

Researchers seem to have solved the puzzle of LK-99. Scientific detective work has unearthed evidence that the material is not a superconductor, and clarified its actual properties. Nature: The conclusion dashes hopes that LK-99 -- a compound of copper, lead, phosphorus and oxygen -- marked the discovery of the first superconductor that works at room temperature and ambient pressure. Instead, studies have shown that impurities in the material -- in particular, copper sulfide -- were responsible for the sharp drops in electrical resistivity and partial levitation over a magnet, which looked similar to properties exhibited by superconductors. "I think things are pretty decisively settled at this point," says Inna Vishik, a condensed-matter experimentalist at the University of California, Davis.

The LK-99 saga began in late July, when a team led by Sukbae Lee and Ji-Hoon Kim at the Quantum Energy Research Centre, a start-up firm in Seoul, published preprints claiming that LK-99 is a superconductor at normal pressure and temperatures up to at least 127C (400 kelvin). All previously confirmed superconductors function only at extreme temperatures and pressures. The extraordinary claim quickly grabbed the attention of the science-interested public and researchers, some of whom tried to replicate LK-99. Initial attempts did not see signs of room-temperature superconductivity, but were not conclusive. Now, after dozens of replication efforts, many experts are confidently saying that the evidence shows LK-99 is not a room-temperature superconductor. The South Korean team based its claim on two of LK-99's properties: levitation above a magnet and abrupt drops in resistivity. But separate teams in Beijing, at Peking University and the Chinese Academy of Sciences (CAS), found mundane explanations for these phenomena.

Another study, by US and European researchers, combined experimental and theoretical evidence to demonstrate how LK-99's structure made superconductivity infeasible. And other experimenters synthesized and studied pure samples of LK-99, erasing doubts about the material's structure and confirming that it is not a superconductor, but an insulator. The only further confirmation would come from the Korean team sharing their samples, says Michael Fuhrer, a physicist at Monash University in Melbourne, Australia. "The burden's on them to convince everybody else," he says. Perhaps the most striking evidence for LK-99's superconductivity was a video taken by the Korean team that showed a coin-shaped sample of silvery material wobbling over a magnet. The team said the sample was levitating because of the Meissner effect -- a hallmark of superconductivity in which a material expels magnetic fields. Multiple unverified videos of LK-99 levitating subsequently circulated on social media, but none of the researchers who initially tried to replicate the findings observed any levitation.

The United States Space Force has activated its first and only unit dedicated to targeting other nations' satellites and the ground stations that support them. Space.com reports: The 75th Intelligence, Surveillance and Reconnaissance Squadron (ISRS) was activated on Aug. 11 at Peterson Space Force Base in Colorado. This unit is part of Space Delta 7, an element of the U.S. Space Force tasked with providing intelligence on adversary space capabilities. It'll do things like analyze the capabilities of potential targets, locate and track these targets as well as participate in "target engagement," which presumably refers to destroying or disrupting adversary satellites, the ground stations that support them and transmissions sent between the two.

Master Sgt. Desiree Cabrera, 75th ISRS operations superintendent, said the new unit will revolutionize the targeting capabilities of not just the Space Force, but also the entire U.S. military: "Not only are we standing up the sole targeting squadron in the U.S. Space Force, we are changing the way targeting is done across the joint community when it comes to space and electromagnetic warfare." The 75th ISRS will also analyze adversary space capabilities including "counterspace force threats," according to the Space Force's statement. Counterspace forces refer to adversary systems aimed at preventing the U.S. from using its own satellites during a conflict.