A Chinese scientist who was imprisoned for his role in creating the world's first genetically edited babies says he has returned to his laboratory to work on the treatment of Alzheimer's and other genetic diseases. From a report: In an interview with a Japanese newspaper, He Jiankui said he had resumed research on human embryo genome editing, despite the controversy over the ethics of artificially rewriting genes, which some critics predicted would lead to demand for "designer babies."

"We will use discarded human embryos and comply with both domestic and international rules," He told the Mainichi Shimbun, adding that he had no plans to produce more genome-edited babies. Previously, He had used a tool known as Crispr-Cas9 to rewrite DNA in embryos. In 2019 a court in China sentenced He to three years in prison for violating medical regulations after he claimed the previous year that he had created genetically modified twin sisters, Lulu and Nana, before birth. His experiments sent shockwaves through the medical and scientific world. He was widely condemned for having gone ahead with the risky, ethically contentious and medically unjustified procedure with inadequate consent from the families involved.

The court found that He had forged documents from an ethics review panel that were used to recruit couples for his research. He said he had used a gene-editing procedure known as Crispr-Cas9 to rewrite the DNA in the sisters' embryos -- modifications he claimed would make the children immune to HIV. He has continued to defend his work, despite widespread criticism, saying he was "proud" of having created Lulu and Nana. A third girl was born in 2019 as a result of similar experiments.

"Be it enacted by the Legislature of the State of Arizona..." reads the official text of House Bill #2,477. "PLUTO IS THE OFFICIAL STATE PLANET."

An anonymous reader shared this report from Capital Media Services: The governor signed legislation Friday designating Pluto as Arizona's "official state planet." It joins a list of other items the state has declared to be "official,'' ranging from turquoise as the state gemstone and copper as the state metal to the Sonorasaurus as the state dinosaur. "I am proud of Arizona's pioneering work in space discovery," governor Hobbs said.

What makes Pluto unique and ripe for claim by Arizona is that it is the only planet actually discovered in the United States, and the discovery was made in Flagstaff. Rep. Justin Wilmeth, a Phoenix Republican and self-described "history nerd,'' said that needed to be commemorated, starting with the legacy of astronomer Clyde Tombaugh. In 1930, Tombaugh was working at the Lowell Observatory in Flagstaff. "The whole story of Clyde is just amazing, just sitting there under the telescope'' looking for planets by taking photos over a period of time, said Wilmeth. "It was two different glass planes that had one little spec of light moving in a different direction,'' showing it wasn't just another star — and all by observation and not computers. "To me, that's something that's just mind boggling."
"The International Astronomical Union voted years ago to strip Pluto of its official status as a planet," the article points out, noting that its official definition specifies that planets "clear the neighboring region of other objects." (While Pluto "has such a small gravitational pull, it has not attracted and absorbed other space rocks in its orbit".)

So in 2006 Pluto was reclassified as a dwarf planet, according to a NASA web page. "Pluto is about 1/6 the width of Earth," and has a radius of 715 miles or 1,151 kilometers. "If Earth was the size of a nickel, Pluto would be about as big as a popcorn kernel."

Long-time Slashdot reader Baron_Yam called Arizona's new legislation "How to advertise you are ignorant. Scientists said something we don't like, so we'll make a law!" They can call it their "State Planet" all they want, but people who actually know about the skies will be mocking them for it. While there is nostalgia for the old classification, and the new one isn't perfect... it's certainly more meaningful when trying to divide up the objects of a planetary system for study.
Reached for a comment by Capital Media Services, Representative Wilmeth said "It might matter to some that are going to get picky or persnickety about stuff... There's several generations of Americans ... who believe that Pluto's a planet — or at least that's what we were taught. I'm never going to think differently. That's just my personal opinion." (The news site adds that "What is important, Wilmeth said, is remembering the history and promoting it.")

Five senators in Arizona's state legislatur did vote against the measure — though not all of them did so for scientific reasons, Senator Anthony Kern explained to Capital Media Services. "I did not want to discriminate against those who wanted Mars, Venus, Jupiter, or everyone's favorite, Uranus."

As a department of America's federal Health agency, the Food and Drug Administration is responsible for public health rules, including prescription medicines. And the FDA "has not changed its position that currently available clinical trial data do not demonstrate that ivermectin is effective against COVID-19," they confirmed to CNN this week. "The agency has not authorized or approved ivermectin for use in preventing or treating COVID-19."

But there was also a lawsuit. In "one of its more popular pandemic-era social media campaigns," the agency tweeted out "You are not a horse. You are not a cow. Seriously, y'all. Stop it." The post attracted nearly 106,000 likes — and over 46,000 reposts, and was followed by another post on Instagram. "Stop it with the #ivermectin. It's not authorized for treating #COVID."

Los Angeles Times business columnist Michael Hiltzik writes that the posts triggered a "groundless" lawsuit: It was those latter two lines that exercised three physicians who had been prescribing ivermectin for patients. They sued the FDA in 2022, asserting that its advisory illegally interfered with the practice of medicine — specifically with their ability to continue prescribing the drug. A federal judge in Texas threw out their case, but the 5th Circuit Court of Appeals — the source of a series of chuckleheaded antigovernment rulings in recent years — reinstated it last year, returning it to the original judge for reconsideration.

Now the FDA has settled the case by agreeing to delete the horse post and two similar posts from its accounts on the social media platforms X, LinkedIn and Facebook. The agency also agreed to retire a consumer advisory titled "Why You Should Not Use Ivermectin to Treat or Prevent COVID-19." In defending its decision, the FDA said it "has chosen to resolve this lawsuit rather than continuing to litigate over statements that are between two and nearly four years old."

That sounds reasonable enough, but it's a major blunder. It leaves on the books the 5th Circuit's adverse ruling, in which a panel of three judges found that the FDA's advisory crossed the line from informing consumers, which they said is all right, to recommending that consumers take some action, which they said is not all right... That's a misinterpretation of the law and the FDA's actions, according to Dorit Rubinstein Reiss of UC College of the Law in San Francisco. "The FDA will seek to make recommendations against the misuse of products in the future, and having that decision on the books will be used to litigate against it," she observed after the settlement.
"A survey by Boston University and the University of Michigan estimated that Medicare and private insurers had wasted $130 million on ivermectin prescriptions for COVID in 2021 alone."

"Researchers have successfully transformed CO2 into methanol," reports SciTechDaily, "by shining sunlight on single atoms of copper deposited on a light-activated material, a discovery that paves the way for creating new green fuels." Tara LeMercier, a PhD student who carried out the experimental work at the University of Nottingham, School of Chemistry, said: "We measured the current generated by light and used it as a criterion to judge the quality of the catalyst. Even without copper, the new form of carbon nitride is 44 times more active than traditional carbon nitride. However, to our surprise, the addition of only 1 mg of copper per 1 g of carbon nitride quadrupled this efficiency. Most importantly the selectivity changed from methane, another greenhouse gas, to methanol, a valuable green fuel."

Professor Andrei Khlobystov, School of Chemistry, University of Nottingham, said: "Carbon dioxide valorization holds the key for achieving the net-zero ambition of the UK. It is vitally important to ensure the sustainability of our catalyst materials for this important reaction. A big advantage of the new catalyst is that it consists of sustainable elements — carbon, nitrogen, and copper — all highly abundant on our planet." This invention represents a significant step towards a deep understanding of photocatalytic materials in CO2 conversion. It opens a pathway for creating highly selective and tuneable catalysts where the desired product could be dialed up by controlling the catalyst at the nanoscale.
"The research has been published in the Sustainable Energy & Fuels journal of the Royal Society of Chemistry."

Thanks to long-time Slashdot reader Baron_Yam for sharing the article.

Longtime Slashdot reader necro81 writes: The New York Times has an occasional series called "Overlooked," whereby notable people whose deaths were overlooked at the time receive the obituary they deserve. Their latest installment eulogizes Henrietta Swan Leavitt, who passed away in 1921 at age 53. From the report: "In the early 20th century, when Henrietta Leavitt began studying photographs of distant stars at the Harvard College Observatory, astronomers had no idea how big the universe was... Leavitt, working as a poorly paid member of a team of mostly women [computers] who cataloged data for the scientists at the observatory, found a way to peer out into the great unknown and measure it."

Leavitt discovered the period-luminosity relationship for Cepheid variable stars. The relationship, now known as Leavitt's Law, is a crucial rung in the cosmic distance ladder, the methods for measuring the distance to stars, galaxies, and across the visible universe. From the report: "[Leavitt's Law] underpinned the research of other pioneering astronomers, including Edwin Hubble and Harlow Shapley, whose work in the years after World War I demolished long-held ideas about our solar system's place in the cosmos. Leavitt's Law has been used on the Hubble Telescope and the James Webb Space Telescope in making new calculations about the rate of expansion of the universe and the proximity of stars billions of light years from earth. 'She cracked into something that was not only impressive scientifically but shifted an entire paradigm of thinking...'"

When a long-term memory forms, some brain cells experience a rush of electrical activity so strong that it snaps their DNA. Then, an inflammatory response kicks in, repairing this damage and helping to cement the memory, a study in mice shows. Nature: The findings, published on 27 March in Nature, are "extremely exciting," says Li-Huei Tsai, a neurobiologist at the Massachusetts Institute of Technology in Cambridge who was not involved in the work. They contribute to the picture that forming memories is a "risky business," she says. Normally, breaks in both strands of the double helix DNA molecule are associated with diseases including cancer. But in this case, the DNA damage-and-repair cycle offers one explanation for how memories might form and last.

It also suggests a tantalizing possibility: this cycle might be faulty in people with neurodegenerative diseases such as Alzheimer's, causing a build-up of errors in a neuron's DNA, says study co-author Jelena Radulovic, a neuroscientist at the Albert Einstein College of Medicine in New York City. [...] To better understand the part these DNA breaks play in memory formation, Radulovic and her colleagues trained mice to associate a small electrical shock with a new environment, so that when the animals were once again put into that environment, they would 'remember' the experience and show signs of fear, such as freezing in place. Then the researchers examined gene activity in neurons in a brain area key to memory -- the hippocampus. They found that some genes responsible for inflammation were active in a set of neurons four days after training. Three weeks after training, the same genes were much less active.

An anonymous reader shares a report: According to the Ancient Greek philosopher Pythagoras, 'consonance' -- a pleasant-sounding combination of notes -- is produced by special relationships between simple numbers such as 3 and 4. More recently, scholars have tried to find psychological explanations, but these 'integer ratios' are still credited with making a chord sound beautiful, and deviation from them is thought to make music 'dissonant,' unpleasant sounding.

But researchers from the University of Cambridge, Princeton and the Max Planck Institute for Empirical Aesthetics, have now discovered two key ways in which Pythagoras was wrong. Their study, published in Nature Communications, shows that in normal listening contexts, we do not actually prefer chords to be perfectly in these mathematical ratios. "We prefer slight amounts of deviation. We like a little imperfection because this gives life to the sounds, and that is attractive to us," said co-author, Dr Peter Harrison, from Cambridge's Faculty of Music and Director of its Centre for Music and Science.

The researchers also found that the role played by these mathematical relationships disappears when you consider certain musical instruments that are less familiar to Western musicians, audiences and scholars. These instruments tend to be bells, gongs, types of xylophones and other kinds of pitched percussion instruments. In particular, they studied the 'bonang,' an instrument from the Javanese gamelan built from a collection of small gongs.

Two nights of broken sleep are enough to make people feel years older, according to researchers, who said consistent, restful slumber was a key factor in helping to stave off feeling one's true age. From a report: Psychologists in Sweden found that, on average, volunteers felt more than four years older when they were restricted to only four hours of sleep for two consecutive nights, with some claiming the sleepiness made them feel decades older. The opposite was seen when people were allowed to stay in bed for nine hours, though the effect was more modest, with participants in the study claiming to feel on average three months younger than their real age after ample rest.

"Sleep has a major impact on how old you feel and it's not only your long-term sleep patterns," said Dr Leonie Balter, a psychoneuroimmunologist at the Karolinska Institute in Stockholm and first author on the study. "Even when you only sleep less for two nights that has a real impact on how you feel." Beyond simply feeling more decrepit, the perception of being many years older may affect people's health, Balter said, by encouraging unhealthy eating, reducing physical exercise, and making people less willing to socialise and engage in new experiences.

Gizmodo reports that increased activity on the Moon "may affect the unique radio silence on the lunar far side, an ideal location for radio telescopes to pick up faint signals from the cosmic past." This week, the International Academy of Astronautics (IAA) held the first Moon Farside Protection Symposium in Italy to advocate for preserving radio silence on the far side of the Moon. The symposium hopes to raise awareness about the threat facing the far side of the Moon and develop approaches to shielding it from artificial radio emissions....

NASA has shown interest in using the lunar radio silence, proposing an ultra-long-wavelength radio telescope inside a crater on the far side of the Moon. The Lunar Crater Radio Telescope is designed to observe the universe at frequencies below 30 megahertz, which are largely unexplored by humans since those signals are reflected by the Earth's ionosphere, according to NASA. At those low frequencies, radio telescopes on the Moon can detect near-Earth objects approaching our planet before other observatories, it can search for signals of alien civilizations, and study organic molecules in interstellar space...

As more missions head towards the Moon, however, that perfect silence is increasingly being compromised. Earlier this week, for example, China launched a satellite to relay communication between ground operations on Earth and an upcoming mission on the far side of the Moon. The satellite, Queqiao-2, is the first of a constellation of satellites that China hopes to deploy by 2040 to communicate with future crewed missions on the Moon and Mars. As part of its Artemis program, NASA is aiming to build the Lunar Gateway, a space station designed to orbit the Moon to support future missions to the lunar surface and Mars. In advance of this, a NASA-funded cubesat, called CAPSTONE, has entered into a unique halo orbit to demonstrate the stability and practicality of this trajectory for future lunar missions... CAPSTONE marks the beginning of something big — establishing a permanent communication link between Earth and lunar assets, and ensuring the steady, uninterrupted flow of data.

NASA and its Chinese counterparts have eerily similar plans for lunar exploration, and the Moon is currently a 'free-for-all' with no regulations set in place as to who can own our dusty orbital companion.
"In other words, things are about to get real loud out there as far as radio transmissions are concerned."

Slashdot reader sciencehabit shared this report from Science magazine: Nurturing a growing fetus requires a series of profound physical, hormonal, and chemical changes that may rewire every major organ in the body and can cause serious health complications such as hypertension and preeclampsia. But does being pregnant actually take years off your life...?

Today in Cell Metabolism, scientists report that the stress of pregnancy can cause a person's biological age to increase by up to 2 years — a trend that may reverse itself in the months that follow. In some cases, the authors write, those who breastfeed their children after giving birth may end up biologically "younger" than during early pregnancy. The finding represents yet another piece of "compelling" evidence that events during and after pregnancy can have far-reaching health consequences, says Elizabeth Bertone-Johnson, an epidemiologist at the University of Massachusetts Amherst who wasn't involved in the new study...

The discovery that biological aging isn't necessarily a linear process "came as a real surprise," says Kieran O'Donnell, a perinatal researcher at the Yale School of Medicine... But blood samples from 68 participants, collected 3 months after giving birth, revealed a dramatic about-face. Although being pregnant had initially aged their cells between 1 and 2 years, says O'Donnell, their biological age now appeared to be 3 to 8 years younger than it had been during early pregnancy — with different epigenetic clocks algorithms providing slightly bigger or smaller estimates.

An AI tool named Mia, tested by the NHS, successfully detected signs of breast cancer in 11 women which had been missed by human doctors. The BBC reports: The tool, called Mia, was piloted alongside NHS clinicians and analyzed the mammograms of over 10,000 women. Most of them were cancer-free, but it successfully flagged all of those with symptoms, as well as an extra 11 the doctors did not identify. At their earliest stages, cancers can be extremely small and hard to spot. The BBC saw Mia in action at NHS Grampian, where we were shown tumors that were practically invisible to the human eye. But, depending on their type, they can grow and spread rapidly.

Barbara was one of the 11 patients whose cancer was flagged by Mia but had not been spotted on her scan when it was studied by the hospital radiologists. Because her 6mm tumor was caught so early she had an operation but only needed five days of radiotherapy. Breast cancer patients with tumors which are smaller than 15mm when discovered have a 90% survival rate over the following five years. Barbara said she was pleased the treatment was much less invasive than that of her sister and mother, who had previously also battled the disease. Without the AI tool's assistance, Barbara's cancer would potentially not have been spotted until her next routine mammogram three years later. She had not experienced any noticeable symptoms. "These results are encouraging and help to highlight the exciting potential AI presents for diagnostics. There is no question that real-life clinical radiologists are essential and irreplaceable, but a clinical radiologist using insights from validated AI tools will increasingly be a formidable force in patient care." said Dr Katharine Halliday, President of the Royal College of Radiologists.

An anonymous reader shares a report: Thanks to the vaccination program that began in 1995, chickenpox is now relatively rare. Cases of the miserable, itchy condition have fallen more than 97 percent. But, while children have largely put the oatmeal baths and oven mitts behind them, doctors have apparently let their diagnostic skills get a little crusty. According to a study published Thursday, public health researchers in Minnesota found that 55 percent of people diagnosed with chickenpox based on their symptoms were actually negative for the varicella-zoster virus, the virus that causes chickenpox. The study noted that the people were all diagnosed in person by health care providers in medical facilities. But, instead of chickenpox, lab testing showed that some of the patients were actually infected with an enterovirus, which can cause a rash, or the herpes simplex virus 1, which causes cold sores.

The study, published in the Centers for Disease Control and Prevention's Morbidity and Mortality Weekly Report, supports expanding laboratory testing for suspected chickenpox cases in the state's program and highlights that diagnoses based on symptoms are "unreliable." For one thing, doctors simply see far fewer chickenpox cases these days because of the protection from vaccines. While chickenpox cases in the US previously reached 4 million each year, with 10,500 to 13,500 hospitalizations and 100 to 150 deaths, there are now fewer than 150,000 cases,1,400 hospitalizations, and 30 deaths each year, the CDC reports. Vaccination is more than 90 percent effective at preventing the disease. In the rare cases where a vaccinated person contracts chickenpox, the muted rashes are challenging to identify by eye. But even in unvaccinated children, chickenpox can be tricky to pick out; it can easily be confused with measles, insect bites, enterovirus, skin infections such as scabies and impetigo, herpes viruses, and hand, foot, and mouth disease.

The guardians of the world's official geological timescale have firmly rejected a proposal to declare an Anthropocene epoch, after an epic academic row. From a report: The proposal would have designated the period from 1952 as the Anthropocene to reflect the planet-changing impact of humanity. It would have ended the Holocene epoch, the 11,700 years of stable climate since the last ice age and during which human civilisation arose. The International Union of Geological Sciences (IUGS) has announced, however, that geologists have rejected the idea in a series of votes. Those objecting noted a much longer history of human impacts on Earth, including the dawn of agriculture and the industrial revolution, and unease about including a new unit in the geological timescale with a span of less than less than a single human lifetime, it said. Most units span thousands or millions of years.

It also acknowledged: "The Anthropocene as a concept will continue to be widely used not only by Earth and environmental scientists, but also by social scientists, politicians and economists, as well as by the public at large. As such, it will remain an invaluable descriptor in human-environment interactions." The Anthropocene working group (AWG), which was formed by the Subcommission on Quaternary Stratigraphy (SQS), in turn part of the IUGS, took 15 years to develop the proposal. It concluded that the radioactive isotopes spread worldwide by hydrogen bomb tests were the best marker of humanity's transformation of the planet. Geological time units also need a specific location to typify the unit and the Crawford sinkhole lake in Canada was chosen.

For the first time, surgeons have transplanted a kidney from a genetically modified pig into a living person, doctors in Boston said Thursday. From a report: Richard Slayman, 62, of Weymouth, Mass., who is suffering from end-stage kidney disease, received the organ Saturday in a four-hour procedure, Massachusetts General Hospital announced. He is recovering well and is expected to be discharged soon, the hospital said. "I saw it not only as a way to help me, but a way to provide hope for the thousands of people who need a transplant to survive," Slayman said in a statement released by the hospital.

The procedure is the latest development in a fast-moving race to create genetically modified pigs to provide kidneys, livers, hearts and other organs to help alleviate the shortage of organs for people who need transplants. "Our hope is that this transplant approach will offer a lifeline to millions of patients worldwide who are suffering from kidney failure," said Dr. Tatsuo Kawai, the hospital's director for clinical transplant tolerance, in the hospital statement.

Several biotech companies are racing to develop a supply of cloned pigs whose DNA has been genetically modified so they won't be rejected by the human body, spread pig viruses to people or cause other complications. NPR recently got exclusive access to a research farm breeding these animals for a company in this competition, Revivicor Inc. of Blacksburg, Va. The kidney transplanted in Boston came from a pig created by eGenesis of Cambridge, Mass. The eGenesis pigs are bred with 69 genetic modifications to prepare organs for human transplantation. The changes protect against a virus known to infect pigs as well as delete pig genes and add human genes to make the organs compatible with people.

A physicist who shot to fame with claims of the discovery of a room-temperature superconductor engaged in research misconduct, a committee tapped to examine his work has concluded after a monthslong investigation. From a report: Ranga Dias, a physicist at the University of Rochester in New York, has had at least four papers he co-wrote, including three involving superconductivity, retracted in the past 18 months by the journals that published them. A committee of outside experts tapped by the university "identified data-reliability concerns in those papers," a Rochester spokesperson told The Wall Street Journal. "The committee concluded, in accordance with university policy and federal regulations, that Dias engaged in research misconduct," the spokesperson said in an emailed statement.

The work in the papers was funded by the National Science Foundation, the Energy Department, and the Gordon and Betty Moore Foundation, a private organization that funds scientific research. The Moore foundation discontinued its grant late last year, the organization said. Of the $1.6 million award, about $285,000 was spent. The university refunded the rest. The investigation follows three preliminary reviews by the university of one of the studies, published in Nature in 2020 and retracted in 2022 after criticism from other scientists. Those inquiries didn't find enough evidence to prompt a full investigation. Complaints sent to the university in spring 2023 about additional studies prompted a more thorough review. That investigation was completed by March this year, resulting in the misconduct finding. The journal Nature reported earlier this month that this investigation was complete.

Neuralink, the brain-chip startup founded by Elon Musk, showed its first patient using his mind to play online chess. Reuters reports: Noland Arbaugh, the 29-year-old patient who was paralyzed below the shoulder after a diving accident, played chess on his laptop and moved the cursor using the Neuralink device. The implant seeks to enable people to control a computer cursor or keyboard using only their thoughts. Arbaugh had received an implant from the company in January and could control a computer mouse using his thoughts, Musk said last month.

"The surgery was super easy," Arbaugh said in the video streamed on Musk's social media platform X, referring to the implant procedure. "I literally was released from the hospital a day later. I have no cognitive impairments. I had basically given up playing that game," Arbaugh said, referring to the game Civilization VI, "you all (Neuralink) gave me the ability to do that again and played for 8 hours straight."

Elaborating on his experience with the new technology, Arbaugh said that it is "not perfect" and they "have run into some issues." "I don't want people to think that this is the end of the journey, there's still a lot of work to be done, but it has already changed my life," he added.

schwit1 shares a report from ScienceAlert: Sound waves fossilized in the maps of galaxies across the Universe could be interpreted as signs of a Big Bang that took place 13 billion years earlier than current models suggest. Last year, theoretical physicist Rajendra Gupta from the University of Ottawa in Canada published a rather extraordinary proposal that the Universe's currently accepted age is a trick of the light, one that masks its truly ancient state while also ridding us of the need to explain hidden forces. Gupta's latest analysis suggests oscillations from the earliest moments in time preserved in large-scale cosmic structures support his claims. "The study's findings confirm that our previous work about the age of the Universe being 26.7 billion years has allowed us to discover that the Universe does not require dark matter to exist," says Gupta. "In standard cosmology, the accelerated expansion of the Universe is said to be caused by dark energy but is in fact due to the weakening forces of nature as it expands, not due to dark energy." [...]

Current cosmological models make the reasonable assumption that certain forces governing the interactions of particles have remained constant throughout time. Gupta challenges a specific example of this 'coupling constant', asking how it might affect the spread of space over exhaustively long periods of time. It's hard enough for any novel hypothesis to survive the intense scrutiny of the scientific community. But Gupta's suggestion isn't even entirely new -- it's loosely based on an idea that was shown the door nearly a century ago. In the late 1920s, Swiss physicist Fritz Zwicky wondered if the reddened light of far distant objects was a result of lost energy, like a marathon runner exhausted by a long journey across the eons of space. His 'tired light' hypothesis was in competition with the now-accepted theory that light's red-shifted frequency is due to the cumulative expansion of space tugging at light waves like a stretched spring.

The consequences of Gupta's version of the tired light hypothesis -- what is referred to as covarying coupling constants plus tired light, or CCC+TL -- would affect the Universe expansion, doing away with mysterious pushing forces of dark energy and blaming changing interactions between known particles for the increased stretching of space. To replace existing models with CCC+TL, Gupta would need to convince cosmologists his model does a better job of explaining what we see at large. His latest paper attempts to do that by using CCC+TL to explain fluctuations in the spread of visible matter across space caused by sound waves in a newborn Universe, and the glow of ancient dawn known as the cosmic microwave background. While his analysis concludes his hybrid tired light theory can play nicely with certain features of the Universe's residual echoes of light and sound, it does so only if we also ditch the idea that dark matter is also a thing. The research has been published in The Astrophysical Journal.

The European Union has agreed to launch four Galileo navigation satellites on SpaceX's Falcon 9 rocket at a 30 percent premium over the standard launch price. Ars Technica reports: According to Politico, the security agreement permits staff working for the EU and European Space Agency to have access to the launch pad at all times and, should there be a mishap with the mission, the first opportunity to retrieve debris. With the agreement, final preparations can begin for two launches of two satellites each, on the Falcon 9 rocket from Florida. These Galileo missions will occur later this year. The satellites, which each weigh about 700 kg, will be launched into an orbit about 22,000 km above the planet.

The heightened security measures are due to the proprietary technology incorporated into the satellites, which cost hundreds of millions of euros to build; they perform a similar function to US-manufactured Global Positioning System satellites. The Florida launches will be the first time Galileo satellites, which are used for civilian and military purposes, have been exported outside of European territory. Due to the extra overhead related to the national security mission, the European Union agreed to pay 180 million euros for the two launches, or about $196 million. This represents about a 30 percent premium over the standard launch price of $67 million for a Falcon 9 launch. Over the past two years, the European Space Agency (ESA) had to rely on SpaceX for several launches, including significant projects like the Euclid space telescope and other ESA satellites, due to the cessation of collaborations with Roscosmos after the invasion of Ukraine and delays in the Ariane 6 rocket's development. With the Ariane 5 retired and no immediate replacement, Europe's access to space was compromised.

That said, the Ariane 6 is working towards a launch window in the coming months, promising a return to self-reliance for ESA with a packed schedule of missions ahead.

Several readers shared the following report: Intermittent fasting, a diet pattern that involves alternating between periods of fasting and eating, can lower blood pressure and help some people lose weight, past research has indicated. But an analysis presented Monday at the American Heart Association's scientific sessions in Chicago challenges the notion that intermittent fasting is good for heart health. Instead, researchers from Shanghai Jiao Tong University School of Medicine in China found that people who restricted food consumption to less than eight hours per day had a 91% higher risk of dying from cardiovascular disease over a median period of eight years, relative to people who ate across 12 to 16 hours.

It's some of the first research investigating the association between time-restricted eating (a type of intermittent fasting) and the risk of death from cardiovascular disease. The analysis -- which has not yet been peer-reviewed or published in an academic journal -- is based on data from the Centers for Disease Control and Prevention's National Health and Nutrition Examination Survey collected between 2003 and 2018. The researchers analyzed responses from around 20,000 adults who recorded what they ate for at least two days, then looked at who had died from cardiovascular disease after a median follow-up period of eight years. However, Victor Wenze Zhong, a co-author of the analysis, said it's too early to make specific recommendations about intermittent fasting based on his research alone.

The Associated Press reports on the passing of astronaut Thomas P. Stafford, the commander of a dress rehearsal flight for the 1969 moon landing and the first U.S.-Soviet space linkup. He was 93. From the report: Stafford, a retired Air Force three-star general, took part in four space missions. Before Apollo 10, he flew on two Gemini flights, including the first rendezvous of two U.S. capsules in orbit. He died in a hospital near his Space Coast Florida home, said Max Ary, director of the Stafford Air & Space Museum in Weatherford, Oklahoma. Stafford was one of 24 NASA astronauts who flew to the moon, but he did not land on it. Only seven of them are still alive. After he put away his flight suit, Stafford was the go-to guy for NASA when it sought independent advice on everything from human Mars missions to safety issues to returning to flight after the 2003 space shuttle Columbia accident. He chaired an oversight group that looked into how to fix the then-flawed Hubble Space Telescope, earning a NASA public service award.

"Tom was involved in so many things that most people were not aware of, such as being known as the 'Father of Stealth,'" Ary said in an email. Stafford was in charge of the famous 'Area 51' desert base that was the site of many UFO theories, but the home of testing of Air Force stealth technologies. The Apollo 10 mission in May 1969 set the stage for Apollo 11's historic mission two months later. Stafford and Gene Cernan took the lunar lander nicknamed Snoopy within 9 miles (14 kilometers) of the moon's surface. Astronaut John Young stayed behind in the main spaceship dubbed Charlie Brown. "The most impressive sight, I think, that really changed your view of things is when you first see Earth," Stafford recalled in a 1997 oral history, talking about the view from lunar orbit. Then came the moon's far side: "The Earth disappears. There's this big black void." Apollo 10's return to Earth set the world's record for fastest speed by a crewed vehicle at 24,791 mph (39,897 kph).

After the moon landings ended, NASA and the Soviet Union decided on a joint docking mission and Stafford, a one-star general at the time, was chosen to command the American side. It meant intensive language training, being followed by the KGB while in the Soviet Union, and lifelong friendships with cosmonauts. The two teams of space travelers even went to Disney World and rode Space Mountain together before going into orbit and joining ships. "We have capture," Stafford radioed in Russian as the Apollo and Soyuz spacecraft hooked up. His Russian counterpart, Alexei Leonov, responded in English: "Well done, Tom, it was a good show. I vote for you." [...] The 1975 mission included two days during which the five men worked together on experiments. After, the two teams toured the world together, meeting President Gerald Ford and Soviet leader Leonid Brezhnev. "It helped prove to the rest of the world that two completely opposite political systems could work together," Stafford recalled at a 30th anniversary gathering in 2005. Later, Stafford was a central part of discussions in the 1990s that brought Russia into the partnership building and operating the International Space Station.