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Medicine

Weight-Loss Surgery Down 25% as Anti-Obesity Drug Use Soars (harvard.edu) 159

A new study examining a large sample of privately insured patients with obesity found that use of drugs such as Ozempic and Wegovy as anti-obesity medications more than doubled from 2022 to 2023. During that same period, there was a 25.6% decrease in patients undergoing metabolic bariatric surgery to treat obesity. From a report: The study, by researchers at Brigham and Women's Hospital, in collaboration with researchers at Harvard T.H. Chan School of Public Health and the Brown School of Public Health, is published in JAMA Network Open. "Our study provides one of the first national estimates of the decline in utilization of bariatric metabolic surgery among privately insured patients corresponding to the rising use of blockbuster GLP-1 RA drugs," said senior author Thomas C. Tsai, a metabolic bariatric surgeon at Brigham and Women's Hospital.

Using a national sample of medical insurance claims data from more than 17 million privately insured adults, the researchers identified patients with a diagnosis of obesity without diabetes in 2022-2023. The study found a sharp increase in the share of patients who received glucagon-like peptide-1 receptor agonists, or GLP-1 RAs, during the study period, with GLP-1 RA use increasing 132.6% from the last six months of 2022 to the last six months of 2023 (from 1.89 to 4.41 patients per 1,000 patients).

Meanwhile, there was a 25.6% decrease in use of bariatric metabolic surgery during the same period (from 0.22 to 0.16 patients per 1,000 patients). Among the sample of patients with obesity, 94.7% received neither form of treatment during the study period (while 5% received GLP-1 RAs and 0.3% received surgery). Compared to patients who were prescribed GLP-1 RAs, patients who underwent surgery tended to be more medically complex.

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Weight-Loss Surgery Down 25% as Anti-Obesity Drug Use Soars

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  • by ZipNada ( 10152669 ) on Thursday October 31, 2024 @09:28AM (#64908933)

    “Metabolic bariatric surgery and GLP-1 RAs are both effective interventions for patients with obesity, yet less than 6 percent of patients in our study received either form of treatment.”

    Understandable in a way. The drugs are expensive and can have serious side effects. The average cost of bariatric surgery ranges between $17,000 and $26,000, but it reportedly is relatively safe and often results in significant weight loss.

    https://www.saintalphonsus.org... [saintalphonsus.org]

    • "...and often results in significant weight loss" True, but they weight can come back over time.
      • >> weight can come back over time

        Very true, you have to keep taking the expensive weight loss drugs that have side effects but the bariatric surgery is a one-time thing.

  • When you're eating enough to be fat enough it is having a serious negative effect on your life and you're not willing to reduce your food intake... That's a mental issue. A behavior you can't manage to change.

    Drugs and surgery are temporary corrections of the symptom, if you don't deal with the problem - wanting and consuming too much food - you're going to need more drugs or surgery, or you're going to get fat again.

    • by AmiMoJo ( 196126 ) on Thursday October 31, 2024 @09:43AM (#64908975) Homepage Journal

      Over 2/3rds of Americans are overweight or obese. That seems to rule out mental problems, because what is a normal mental state is defined by the behaviour of the majority. Few people believe in little green men so that's a delusion, but a lot of people believe an omnipotent being controls their life and responds to flattery, so that's perfectly normal.

      Would you also say that people who are addicted to tobacco products also have a "mental issue"? It's not an unreasonable comparison. Food companies are strongly motivated to create products that are addictive, and then use every means they can to induce you to buy them.

      • If you have the capacity to change your behavior and you're suffering because you won't... It's a mental issue no matter how common it is. This can be heavily influenced by your environment and culture, but the truth is that if you WANT to be healthier, it's not impossible to do so without and easy/quick fix solution. You can even eat healthier in addition to eating less, and save money while doing so.

        It takes some effort. Culturally, we're not that big on effort. Most people pretend - taking up a new

        • by AmiMoJo ( 196126 )

          Consider that these medications are not cheap, and a hefty chunk of change every week is a pretty big motivator. Between that, the people fat shaming them, the desire to look conventionally attractive, the health problems obesity causes, the daily inconveniences, the rising cost of food, you would have to assume that the majority of Americans are extremely lazy and willing to put up with a hell of a lot just to avoid your easy and effective solution.

          A more likely explanation is that it is in fact far harder

      • by skam240 ( 789197 )

        That seems to rule out mental problems, because what is a normal mental state is defined by the behaviour of the majority.

        Does it? The number of obese Americans has tripled in the last 60 years https://usafacts.org/articles/... [usafacts.org] which pretty much means there's a mental issue at some level here for a lot of people regardless of whatever "normal" is. Everyone knows eating lots of sweet treats will put pounds on, everyone knows fast food will too. The choice to continue heavily consuming such items despite being able to physically see the negative effects on one's health (the expanding belly) is a mental one.

        And sure, things like

        • by AmiMoJo ( 196126 )

          So your theory is that more than 2/3rds of Americans have developed mental problems, as opposed to the far more likely hypothesis that foods and eating habits have changed dramatically over the last 60 years?

        • Maybe its just the kind of food people are being fed.

          "The rising obesity epidemic in the U.S., as well as related chronic diseases, are correlated with a rise in ultra-processed food consumption. The foods most associated with weight gain include potato chips, sugar sweetened beverages, sweets and desserts, refined grains, red meats, and processed meats"

          https://smhs.gwu.edu/news/proc... [gwu.edu]

      • by CubicleZombie ( 2590497 ) on Thursday October 31, 2024 @10:14AM (#64909065)

        Would you also say that people who are addicted to tobacco products also have a "mental issue"? It's not an unreasonable comparison. Food companies are strongly motivated to create products that are addictive, and then use every means they can to induce you to buy them.

        When my overweight wife would get hungry, she had exactly the same symptoms as when I would be in withdrawal from nicotine.

        • by AmiMoJo ( 196126 )

          I heard the same thing from a friend, and I'm ashamed to say I didn't believe them at the time.

      • by wyHunter ( 4241347 ) on Thursday October 31, 2024 @10:37AM (#64909133)
        "Mental problems," no, but knowledge lack, yes. YES I'm 25 pounds overweight so I'm not on my high horse - but what I see in terms of food with minimal nutrition in people's shopping carts is astounding. OF COURSE people eat too much - they are fat, but starving, because they aren't getting enough nutrition.
      • Over 2/3rds of Americans are overweight or obese. That seems to rule out mental problems, because what is a normal mental state is defined by the behaviour of the majority.

        When you arbitrarily draw a line around a group of people you can define "normal" to mean anything you want it to. Actual figures when you don't play games with statistics show 16% of adults in the world are obese, so no it's not normal. Oh but that's all starving kids in Africa right? Okay lets draw the line but do so somewhere comparable. 17% of adults in the EU are obese. Why do they not need to medicate, and who isn't normal now?

      • It's not just the food companies, it has permeated the whole culture. I'm currently in the US for a short trip and eating out a lot, and one thing I'm looking forward to, when I get back home, is fresh vegetables not drowned in some kind of fat (I do like fat, but there's the issue of proportion). When I have ordered a side of "fresh vegetables" I have regretted it. Don't even get me started on what passes as salad here. I'm sure it's different in different states or regions, however I have seen a few at th

    • by piojo ( 995934 ) on Thursday October 31, 2024 @10:12AM (#64909063)

      I dunno about you, but I eat a lot of real food--things that used to be plants and animals. I'm grateful to be in a position to be able to do that. So would I reduce my food intake without altering my appetite? Maybe someone that eats like crap could say "one fewer bag of crisps per day", but what would I say? One less spoon of chicken and black beans? 25% less olive oil in the hummus? Eat smaller fruit? Unless your food comes from cans and boxes, you can't just eat less. You can do something more nuanced, like alter your appetite, learn to detect fullness earlier, or be hungrier.

      When you're eating enough to be fat enough it is having a serious negative effect on your life and you're not willing to reduce your food intake... That's a mental issue.

      Food for thought: if you eat 1% too much, you will gain over two pounds per year.

    • There are a wide range of physiological reasons why people become obese. I've been packing on some pounds because of back problems making it hard to do the sort of exercise I used to do to keep fit. Also most simply when you gain weight your body creates more cells to store fat but when you lose the weight you don't lose those cells they just get smaller. Basically if you've gotten fat once it's permanently harder to keep the weight off.

      This is before we get into all the gut bacteria problems many of wh
  • by Murdoch5 ( 1563847 ) on Thursday October 31, 2024 @09:34AM (#64908947) Homepage
    * Not everyone does, there is a population that does need real medical intervention, and aren't just lazy, and unwilling to change, this is NOT about that group.

    Okay, how many people are on these drugs, but take no real responsibility? I can name a handful of people, all women, who are on Ozempic, who DO NOT NEED IT. What do I mean, when I say they don't need it? All the people I'm thinking of have the same few points in common:

    1. They have terrible diets.
    2. They've all tried the fad diets, including Keto (which is for intractable epilepsy in kids, who "normal" meds don't work for).
    3. They're very stationary, and their active outputs aren't useful.
    4. This is important, they don't take responsibility!

    Fad dieting, is NOT a method for weight loss, if you move between Keto (which you should NEVER do), Fasting (starvation), FOD MAP (which is nonsense on overdrive), and all the others, you're asking for your body to react negatively. If you eat pasta 4x a week, you're not going to lose weight. If you mix random shakes full of nuts, powders, and fruits, chances are, you're not going to lose weight because, you don't really know what's in the mess you're drinking. Stabilize your diet, so your body knows what to expect, look at what people eat who have low-fat levels, body builders and strongmen. Notice how they share the same diet, protein + simple carbs, and then just copy it adjusting for your body weight.

    Once you have a real diet, that is balanced, then get to the gym, and or get active! You need to be moving, so move weights around, have some cardio, and make sure you're meaningfully and usefully active. If you sit at a desk for 8 hours a day, 5 days a week, you can't be shocked when you put on the pounds, so honestly, get a standing / sitting desk, get a little treadmill and walk while you work. Also, go to the gym, 3x a week, and try to get into some sports if you can, which can be substituted for the gym.

    If you're done those things for a year or two, and you're still gaining weight, then you might actually have a problem, but, doctors today are prescribing Ozempic because after trying Keto 4 times, and FOD MAP for 1 week, after sitting on your ass for 80 hours, you had a cry session that you're a cow, and it's not your fault your fat, it's societies. All the people I'm thinking of, could get active, get a better diet, and stop making excuses, and they would be in better overall health for it. They would ALL get mad at me for saying this, while also trying to eat 10kg of pasta for dinner, covered in thick sugary sauce, with a side salad covered in equal amount of sugar dressing, then insisting I'm not a woman, so I can't understand, then laying down because "Oh, I just don't feel well."
    • by AmiMoJo ( 196126 )

      Human beings evolved when the food supply was unreliable. Plants and animals had not been bread to be larger and higher in fat, or pumped full of hormones.

      Modern foods are produced by people who have a vested interested in selling you as many calories as possible. The US, where this problem is the worst, also has very low food standards compared to other developed nations. Life now doesn't give people much time to prepare or even seek out healthy food.

      It's not the case that people today lack the willpower a

      • by Murdoch5 ( 1563847 ) on Thursday October 31, 2024 @10:20AM (#64909079) Homepage
        That's why you need to stabilize the diet because if you don't fix that first, unless you're genetically lucky, it won't matter. Farmers markets are a great way to find high-quality meat, or, find a local meat distribution company. For the people I'm using as my base, all of them have high-quality meats available. One of them lives within 200 meters of a butcher, in a large city, the others live within a few KM from a butcher, but also near multiple open air food markets during the spring / summer, and next to farms (within a quick drive).

        Again, I need to stress this, I've seen all of them, sit down to LARGE pasta dinners, covered with sugary sauce, with salads that are covered in equally sugary sauce, and then lecture me that the oatmeal I'm eating is bad for me, before I head off to gym. You won't burn off a pasta dinner, unless you're doing balls to the wall, hardcore mode. People think they can eat absolute junk, and the gym will fix that because they did 10 minutes on the StairMaster.
        • by AmiMoJo ( 196126 )

          Around here meat is quite expensive relative to other foods, and farmers markets and butchers tend to be higher priced than supermarkets.

          Pasta is cheap and very easy to prepare.

          • I live in Canada, relevant for the medical notes.

            Yes, it's cheap, and easy, but you can't consume crap, and then at the same time whine about your inability to control your weight. The people I'm referring to are all well off, so groceries are not a burden, but, on the other hand, I know someone whose has a burden paying for the basics. He actually has a legit medical reason to need something like Ozempic, but on some sad notes:

            1. Can't afford it (our family offered to cover it for him).
            2. Can't get
  • by MpVpRb ( 1423381 ) on Thursday October 31, 2024 @10:15AM (#64909069)

    ...less curable than cancer.
    Most people who lose weight with dieting gain it all back and more.
    Some believe it's simple and insult those who fail to achieve healthy weight.

    It's not simple!

    Weight loss surgery is a crude and awful approach. The new drugs are a tiny bit better, but still are not the solution. This is a hard problem. We need research, not hate and insults

    • ...less curable than cancer.

      Of course it is. If you can have a diet that has fewer calories than you burn and yet not lose weight before lack of nutrients causes problems, what does that tell you about the food that is being eaten?

      Our food is engineered to make us as fat as possible. It is extraordinarily difficult to get all the nutrients that are needed and not gain fat simultaneously.

      I do NOT have an issue with weight, so you can try to say that I am just a slovenly person who is unable to control their appetite so everything I sa

  • This is a miracle drug. Not only did I lose 110lbs last year, my blood work is all back in the normal for the first time in 20 years. I eat entirely better with an eye towards nutrition. I also quit drinking (addiction breaking is a very common theme in the Tirzepatide groups) ....go figure.
    I was over weight for 20 years (classic yo-yo dieter. I could lose, but it always came back. I put on 40lbs during the two years I ran marathons)

    What is really cool? I turned 12 people on to the same drug. Combined we
  • I'm not saying that these medications don't have a place, particularly for folks in extreme cases you need a jump start, but the idea that one would have to take these medications for the rest of their lives is awful. I think the part that's missing from the "balanced diet and exercise" message is that it is definitely not a "get thin quick" plan. Healthy weight loss is between 0.5-1lb per week. That means following those "balanced" routines takes a lot of time, and killing yourself in the gym for two we

  • Long term effects of Semaglutide: Allergic Reactions, Depression and anxiety, Gastrointestinal Issues, Hypoglycemia, Kidney Issues, Pancreatitis, Thyroid Tumors
  • Insurance won't cover it for pure weight loss, only for its original use for diabetes. If you buy on your own it will run $20,000/year
  • We could just eat healthier?

  • I don't think the data in the paper is a very accurate representation of the true population. Many insurance plans explicitly exclude bariatric surgery from their covered services, and I'd be surprised if those same plans don't exclude weight loss drugs as well.

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