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Science

Scientists Use Bacteria To Turn Plastic Waste Into Paracetamol (theguardian.com) 13

Bacteria can be used to turn plastic waste into painkillers, researchers have found, opening up the possibility of a more sustainable process for producing the drugs. From a report: Chemists have discovered E coli can be used to create paracetamol, also known as acetaminophen, from a material produced in the laboratory from plastic bottles. "People don't realise that paracetamol comes from oil currently," said Prof Stephen Wallace, the lead author of the research from the University of Edinburgh. "What this technology shows is that by merging chemistry and biology in this way for the first time, we can make paracetamol more sustainably and clean up plastic waste from the environment at the same time."

Writing in the journal Nature Chemistry, Wallace and colleagues report how they discovered that a type of chemical reaction called a Lossen rearrangement, a process that has never been seen in nature, was biocompatible. In other words, it could be carried out in the presence of living cells without harming them. The team made their discovery when they took polyethylene terephthalate (PET) -- a type of plastic often found in food packaging and bottles -- and, using sustainable chemical methods, converted it into a new material.

Scientists Use Bacteria To Turn Plastic Waste Into Paracetamol

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  • Genetic modifications to turn all those microplastics in your body into soothing pain relief.
    • Genetic modifications to turn all those microplastics in your body into soothing pain relief.

      Then all that acetaminophen destroys your liver. No thanks. Micro-plastics or liver transplant? Hmm...

      • Average consumption is ~250mg annually. That's half of one tablet, which makes it 1/4 of a regular dose, and it's not entirely clear how much is retained and what the conversion ratio is. I wouldn't be surprised if other byproducts were more dangerous.

        You're allowed to take 8 paracetamol tablets per day, which means it's safe to purge 16 YEARS worth of microplastics per day, assuming a 1:1 ratio of plastic to paracetamol and no other side effects.

        Unless you convert an entire lifetime of microplastics in a d

  • If they can find the little plastic eating critter that produces an opiate the Pacific garbage patch problem will probably be solved pretty quickly.
  • That the overhead to commercialize and produce this will create more oil waste than to use the old oil-based procedure.
  • of what to do with plastic waste.

  • "People don't realise that paracetamol comes from oil currently"
    What people. Everyone knows that most of our drugs come from hydrocarbons. Also, fertilizer, laxatives, plastics, cosmetics, explosives, artificial flavors and colors, buttloads of food additives, I could go on.. The oil industry finds ways to make all that crude into products.

    "we can make paracetamol more sustainably and clean up plastic waste from the environment at the same time."
    That's extremely optimistic. The amount of plastic waste is in

  • If they could make methamphetamine, diacetylmorphine, or alprazolam, not only would this be a much larger volume of drugs, there'd be an instant industry competing to make the most of them from such easily-obtained precursors.

  • Uhhhh....can we use living organisms to convert plastic waste into something useful AND inert? Drugs are bad...M'Kay!!!! What happens when this gets out in the wild and starts producing this drug, which is deadly in high doses....what happens when it evolves to produce it in enough concentration that it lures fish...they OD...they die...and the ecoli can break them down. Normally, GMOs don't scare me, but this one does.
  • This plastic waste they're talking about... is this the same waste that people put into recycling bins that invariably ends up being burnt or sent to some foreign country to be buried? Because at a gram per dose, paracetamol is not exactly a high volume product is it

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