Scientists Announce Progress Toward Ambitious Atlas of Human Cells (reuters.com) 5
Scientists unveiled on Wednesday the first blueprint of human skeletal development as they make progress toward the goal of completing a biological atlas of every cell type in the body to better understand human health and diagnose and treat disease. From a report: The work is part of the ongoing Human Cell Atlas project that was begun in 2016 and involves researchers around the world. The human body comprises roughly 37 trillion cells, with each cell type having a unique function. The researchers aim to have a first draft of the atlas done in the next year or two.
Aviv Regev, founding co-chair of the project and currently executive vice president and head of research and early development at U.S. biotech company Genentech, said the work is important on two levels. "First of all, it's our basic human curiosity. We want to know what we're made of. I think humans have always wanted to know what they're made of. And, in fact, biologists have been mapping cells since the 1600s for that reason," Regev said. "The second and very pragmatic reason is that this is essential for us in order to understand and treat disease. Cells are the basic unit of life, and when things go wrong, they go wrong with our cells, first and foremost," Regev said.
Aviv Regev, founding co-chair of the project and currently executive vice president and head of research and early development at U.S. biotech company Genentech, said the work is important on two levels. "First of all, it's our basic human curiosity. We want to know what we're made of. I think humans have always wanted to know what they're made of. And, in fact, biologists have been mapping cells since the 1600s for that reason," Regev said. "The second and very pragmatic reason is that this is essential for us in order to understand and treat disease. Cells are the basic unit of life, and when things go wrong, they go wrong with our cells, first and foremost," Regev said.
Re: (Score:2)
That'll win you an atlas to a cell. A jail cell.
A herculean tasks (Score:3)
This task seems very hard to complete. But of course whatever they produce can be very useful. I've been looking at cells for a decades, looking at their genetic expression profiles. I'm really thinking cell types are fluid. You look at the RNA-seq and proteomics of two cells even in the same tissue and there are always some differences. It's a questions of how many differences make the threshold of being called a different cell type? Well some change their profile enough that it's a temporal thing. I mean to the point where I'd call it de-differentiation and differentiation across types.