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Medicine

Microplastics Found In Every Human Placenta Tested In Study (theguardian.com) 105

An anonymous reader quotes a report from The Guardian: Microplastics have been found in every human placenta tested in a study, leaving the researchers worried about the potential health impacts on developing fetuses. The scientists analyzed 62 placental tissue samples and found the most common plastic detected was polyethylene, which is used to make plastic bags and bottles. A second study revealed microplastics in all 17 human arteries tested and suggested the particles may be linked to clogging of the blood vessels. [...] Prof Matthew Campen, at the University of New Mexico, US, who led the research, said: "If we are seeing effects on placentas, then all mammalian life on this planet could be impacted. That's not good." He said the growing concentration of microplastics in human tissue could explain puzzling increases in some health problems, including inflammatory bowel disease (IBD), colon cancer in people under 50, and declining sperm counts. A 2021 study found people with IBD had 50% more microplastics in their feces. Campen said he was deeply concerned by the growing global production of plastics because it meant the problem of microplastics in the environment "is only getting worse."

The research, published in the Toxicological Sciences journal, found microplastics in all the placenta samples tested, with concentrations ranging from 6.5 to 790 micrograms per gram of tissue. PVC and nylon were the most common plastics detected, after polyethylene. The microplastics were analyzed by using chemicals and a centrifuge to separate them from the tissue, then heating them and analyzing the characteristic chemical signature of each plastic. The same technique was used by scientists at the Capital Medical University in Beijing, China, to detect microplastics in human artery samples. The concentration of microplastics in placentas was especially troubling, Campen said. The tissue grows for only eight months, as it starts to form about a month into pregnancy. "Other organs of your body are accumulating over much longer periods of time," he added.

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Microplastics Found In Every Human Placenta Tested In Study

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  • Should I care? (Score:4, Insightful)

    by Somervillain ( 4719341 ) on Tuesday February 27, 2024 @10:51PM (#64274540)
    Serious question...I know "unnatural is bad"...but how bad? Will it shorten my lifespan? healthspan? Will it diminish the quality of my life in some measurable way? What else accumulates in my organs? If I lived on a farm 150 years ago would soil accumulate in the same way? I know it's a big scary unknown....but I don't know how bad it is for you. Perhaps someone here has expertise?
    • Re:Should I care? (Score:5, Informative)

      by ArchieBunker ( 132337 ) on Wednesday February 28, 2024 @12:20AM (#64274662)

      Can’t say I’m a fan of plastic crossing the blood brain barrier. https://www.ncbi.nlm.nih.gov/p... [nih.gov]

      Further research is required.

    • Re:Should I care? (Score:5, Informative)

      by az-saguaro ( 1231754 ) on Wednesday February 28, 2024 @12:58AM (#64274694)

      Serious answer -
      First, compliments for asking a thoughtful well-composed pertinent set of questions.
      The answer in a nutshell - no one yet has clear well-resolved answers to those questions, but over the past 10-15 years there has been a growing awareness of the possible problems of plastics in biological systems, paralleling the concerns about plastics in the environment. As interest in the issue and efforts to investigate ramp up, there are signs of some disturbing associations between plastics and health or disease.

      Things we implant in people are generally metals & alloys, glasses & ceramics, natural fibers, and organic & silicone polymers. Each category and individual material has exhaustive research and clinical development behind it, and unsafe materials have been weeded out from implantable devices. However, "unsafe" is relative. It usually means that a material is non-toxic, i.e. no immediate toxic-metabolic or hyper-immune responses. It also usually implies that a material has been studied for short time (e.g. up to a year) or intermediate time of several years, usually from the point of view of wear and failure, or else fibrosis and loss of effectiveness. The idea that implants deemed safe over 5-10 years might then have tardive (late) complications in 20-50 years has not been answerable for many materials, for many reasons. Some materials have not been in service long enough. Some materials fall "under the radar" because they work well in the short run and then it is assumed that they continue to do well without careful scrutiny in those later years. The doctors who implant devices will rarely have the long term association with a patient that they would hear about a complaint 20 years later, and even if they do, the symptoms will likely present as "intercurrent" complaints not obviously related to the device or its anatomical site. Most companies making implants have been responsible about pursuing safe materials, but in recent decades some have notoriously continued to make and market products known to be detrimental (and why the FDA does not intervene - who knows?). In short, for these reasons, there simply has been little recognition or even reason for suspicion of this problem until recently. Now that concerns have been raised, there will probably be an ongoing rush of new studies along these lines.

      Concerning plastics and polymers, a few things have been known for a long time. Most implant science focuses on short term bio-compatibility, such as not provoking acute inflammation, not being prone to infection, not lysing or breaking, or maintain desirable mechanics (such as an artificial joint not loosening at the metal-bone interface). For plastic implants, inflammation-extrusion and maintaining elastic motion without wear-failure and without fibrosis-stiffness have been the main concerns. To achieve desirable results without short term complications, pertinent factors include precise chemistry of the material, stability of the chemistry in lab and in living biological environments, and even shape, edges, surface textures. Long term serious health risks would predictably fall into several categories - (1) chronic inflammation, immunity, auto-immunity resulting in lupus-like conditions; (2) dysplastic-anaplastic cell transformations leading to cancer; (3) toxic-metabolic effects of unknown or unanticipated metabolites ending up elsewhere in the body, for which late neurological diseases are most likely to present, although liver, kidneys, lungs, and others are also at risk. From that point of view one interesting disease is BIA-ALCL (breast implant associated anaplastic large cell lymphoma) which is rare and occurs only with a specific type of implant with a specific type of silicone surface. (This whole subject is not one I follow too closely these days, so there may be other disorders identified in other specialties, but I suspect there will be more to come in the coming decade or two.) Another well-known issue - silicone joint implants. They were t

    • by quenda ( 644621 )

      Good question!
      They could have tested for plutonium, and I can guarantee every placenta will contain detectable amounts of plutonium.
      That also would make for a great click-bait headline, even though the amount is trivial and harmless.

        Microplastics are new and worth investigating, so researchers should care. But the average person? No, we have too many other things to worry about, and there is nothing we can do about it.

    • Unfortunately, since these seem to be everywhere, it may be problematic to conduct an A/B experiment to find out.
    • RTFA https://www.theguardian.com/en... [theguardian.com]

      Clogging of blood vessels
      Increases in inflammatory bowel disease (IBD)
      Increases in colon cancer in people under 50
      Declining sperm counts
  • "There's a great future in plastics. Think about it. Will you think about it?"

  • Better filtering less filling if you are into the whole eating it.
  • No worries, either climate change or nuclear war will finish us off first.

    • Unlikely either will do that. Lower the population, perhaps, but finish us, unlikely.
      • by Tablizer ( 95088 )

        > but finish us, unlikely.

        If say 95% of the population gets wiped out, the chance that you and I in particular are remaining is small. We still wouldn't be around to worry about microplastics.

  • This is bad news for the food chain. When the humans eat these placentas are, in turn, eaten by worms, there will be a perpetual motion of microplastics.

    Not to mention the lions and cannibals.
    And won't someone think of the zombies?
    How will they cope with microplastics on the brain?

  • Perhaps this is one of the Great Filters implied by the Drake Equation. I truly hope our biosphere survives.
    • I'm not sure fossil fuel would be a universal or common pattern, the deposits we have are from before bacteria had enzymes to break down lignin and wouldn't end up redeposited now even if humanity evaporated overnight.
  • Sure milk cartons are an alternative, but they're not as easily/cheaply manufactured.

  • Some key findings from the Outlook (OECD):

    - Plastic consumption has quadrupled over the past 30 years, driven by growth in emerging markets. Global plastics production doubled from 2000 to 2019 to reach 460 million tonnes. Plastics account for 3.4% of global greenhouse gas emissions.

    - Global plastic waste generation more than doubled from 2000 to 2019 to 353 million tonnes. Nearly two-thirds of plastic waste comes from plastics with lifetimes of under five years, with 40% coming from packaging, 12% f
    • There is 3.5 times more plastic leaked and accumulated in rivers than in oceans.
    • If it were a competition between the plastics industry & humanity, the plastics industry is winning, hands down. We need to up our game.

      Substitute "the plastics industry" with "unfettered capitalism", and you're pretty much right.

  • ... molecules!

    And ... {shudder} ... compounds!

    • They even found organic compounds. You know what contains organic compounds? All sorts of bacteria and parasites!

  • In placenta? I call BS. One would require seasoning their food with powder plastic like we do with salt and pepper to achieve such concentrations.

    • We eagerly await the results of your own study into this issue, at which point you might have something to say worth listening to. Until then it's just blah blah blah yak yak yak

    • Good point, maybe you should become a professional scientist, and show all of these researchers how their college degrees are useless.

  • Just curious because every lab on the planet uses plastic in test equipment.

  • Unless we come up with some cheap, energy efficient way to stop putting plastics in the environment as well as clean up what is already out there, its pretty much in the environment to stay. I'm curious how life will continue to evolve to adapt, like plastic-eating bacteria. How will human bodies adapt? I think being invisible to mosquitos would be cool, but that seems unlikely.

"Once they go up, who cares where they come down? That's not my department." -- Werner von Braun

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