Slashdot is powered by your submissions, so send in your scoop

 



Forgot your password?
typodupeerror
×
Science

Top Harvard Cancer Researchers Accused of Scientific Fraud; 37 Studies Affected (arstechnica.com) 172

An anonymous reader shares a report: The Dana-Farber Cancer Institute, an affiliate of Harvard Medical School, is seeking to retract six scientific studies and correct 31 others that were published by the institute's top researchers, including its CEO. The researchers are accused of manipulating data images with simple methods, primarily with copy-and-paste in image editing software, such as Adobe Photoshop. The accusations come from data sleuth Sholto David and colleagues on PubPeer, an online forum for researchers to discuss publications that has frequently served to spot dubious research and potential fraud. On January 2, David posted on his research integrity blog, For Better Science, a long list of potential data manipulation from DFCI researchers. The post highlighted many data figures that appear to contain pixel-for-pixel duplications. The allegedly manipulated images are of data such as Western blots, which are used to detect and visualize the presence of proteins in a complex mixture.

DFCI Research Integrity Officer Barrett Rollins told The Harvard Crimson that David had contacted DFCI with allegations of data manipulation in 57 DFCI-led studies. Rollins said that the institute is "committed to a culture of accountability and integrity," and that "every inquiry about research integrity is examined fully." The allegations are against: DFCI President and CEO Laurie Glimcher, Executive Vice President and COO William Hahn, Senior Vice President for Experimental Medicine Irene Ghobrial, and Harvard Medical School professor Kenneth Anderson. The Wall Street Journal noted that Rollins, the integrity officer, is also a co-author on two of the studies. He told the outlet he is recused from decisions involving those studies.

This discussion has been archived. No new comments can be posted.

Top Harvard Cancer Researchers Accused of Scientific Fraud; 37 Studies Affected

Comments Filter:
  • Haaa Vaaaahd? (Score:5, Insightful)

    by garyisabusyguy ( 732330 ) on Wednesday January 24, 2024 @02:08PM (#64185363)

    Is this the same Harvard that holds almost $50 BILLION dollars in their endowment?

    And now, we find that they have basically, hamstrung cancer research for decades?

    Am I the only one that feels every single cancer patient should be part of a class action against said institution?

    You cannot string a corporation up by their neck until dead, but people who suffer from their actions deserve recompense, as they say with every sort of crime performed by mere humans, "It will deter others from acting in the same way"

    • a former lover of mine died of cancer a couple of years back and left her entire estate to Dana Farber Cancer Institute... I bet she is now rolling over in her grave!
    • Re: (Score:3, Insightful)

      by Brett Buck ( 811747 )

      The same Harvard who just fired a president for rampant plagiarism, and for whom calling for genocide is gray area that may or may not constitute "harassment" by Harvard student conduct guidelines?

      • Re:Haaa Vaaaahd? (Score:5, Informative)

        by DamnOregonian ( 963763 ) on Wednesday January 24, 2024 @03:20PM (#64185599)
        Having an opinion that anybody should be victim of genocide is not necessarily bullying or harassment. That's simply a fact. It may be vile, but that's a separate thing.
        The context in which that opinion is used, i.e., whether in a bullying or harassing matter, is what matters.

        This person definitely committed plagiarism, but your crude ideological tests are boring.
        The hearing wasn't about "calls for genocide", it was for the adopted definition of anti-semitism to mean anti-Zionism, and anti-Zionism equating to a call for genocide, which is so fucking 1984 it makes one's head spin.
        • Re: (Score:2, Insightful)

          by DarkOx ( 621550 )

          The larger context is that places like these elite universities were nearly always treating certain opinions as harassment; almost regardless of context. Where as other opinions get hide behind the 'free expression of ideas.' As to which opinions being 'acceptable' or not acceptable, and if events are classified as harassing appears to have much more to do with the political alignment of opinion in questions than any ridged legalistic approach to policy enforcement.

          While we normally we don't as a nation, or

          • Basically this person does not exist in the general human population

            That seems bold. In 6 billion people (or 360 million Americans if that's what you're talking about), nobody has those characteristics? We can probably agree Trump nor Biden has them though.

        • Having an opinion that anybody should be victim of genocide is not necessarily bullying or harassment.

          Simply having the opinion clearly is neither bullying or harassment but that's not what was being asked. Actively calling for genocide at a place where the targets of such vile opinions live, work and study, is definitely bullying and harassment. Freedom of speech always has limits and one of those limits is generally threats of and incitement to violence.

          • Nobody called for genocide. That was the point.
            The logic that genocide was called for required the equivocation for "Free Palestine" with the destruction of Israel and the Jews inside of it.
            That may be a real-world result of such a thing, but such a thing was never called for.
      • The last I heard, they did not fire their president - she resigned amongst the controversy despite the claims that many among Harvard's administrators wanted her to remain president.
      • Re:Haaa Vaaaahd? (Score:4, Informative)

        by Moridineas ( 213502 ) on Wednesday January 24, 2024 @05:33PM (#64185883) Journal

        The same Harvard who just fired a president for rampant plagiarism, and for whom calling for genocide is gray area that may or may not constitute "harassment" by Harvard student conduct guidelines?

        Gay was a weak scholar who got the Harvard job in part due to both her plagiarism and her race and gender. I think that's undeniable. While most of her plagiarism was indeed of the most minor variety, some of it was not, and she clearly shows a pattern of plagiarizing. That should be punished, uniformly, across academia. I fully support her being removed from her role for this.

        However, her responses in the Congressional hearing, that raised such ire, particularly amongst the Jewish donor class, are a separate issue.

        https://rollcall.com/2023/12/13/transcript-what-harvard-mit-and-penn-presidents-said-at-antisemitism-hearing/

        Here's a transcript of the hearing. I'm not going to bother attempting to summarize or highlighting the points, but you should read it yourself. What I will say is that Stefanik completely conflated the concepts of "intifada" and "genocide" so that any answer that gave any legitimacy to an intifada would automatically be considered anti-Semitic. In other words, any answer that didn't support the current status of the Palestinian and Israeli nations and peoples would automatically be considered anti-Semitic and the anti-speech fascists want that speech shut down. Stefanik argues that Harvard should not allow any opposition to Israel amongst its students.

        That is unacceptable.

        By those same standards, SUPPORTING the creation of Israel in the 1940 would be considered a genocidal act.

        We have to be able to talk about ideas that other people may find offensive.

        • Those frank discussions are critical, but they are simply not going to be had in a congressional hearing. Not now, and probably not anytime soon. A congressional hearing isn’t for getting to the bottom of something real. You arent even supposed to try and answer the questions. You ignore the questions, grandstand, and spew 1-liners designed to play well on tiktok. The fact that 3 university presidents failed to realize this was surprising to me. The job of a uni president is at least 50% politics.
        • I have given it a read, and this excerpt seems clear to me to not restrict hate speech against Jews:

          ELISE STEFANIK: Well, let me ask you this, will admissions offers be rescinded or any disciplinary action be taken against students or applicants who say from the river to the sea or intifada advocating for the murder of Jews?

          CLAUDINE GAY: As Iâ(TM)ve said that type of hateful reckless offensive speech is personally abhorrent to me.

          Please note that in that question, the murder of Jews is started ex

          • Well, ignoring that Stefanik is presupposing that advocacy for either intifada or usage of the statement ("from the river to the sea, Palestine will be free") means genocide (and I don't universally agree with that presupposition), Gay's continued answer is:

            CLAUDINE GAY: When speech crosses into conduct that violates our policies, including policies against bullying, harassment or intimidation, we take action. And we have robust disciplinary processes that allow us to hold individuals accountable.

            Which again brings me back to my core point. If even saying that Palestinians are allowed to fight back against Israel--Intifada--is genocidal and anti-Semitic, then we have failed as a society that even pretends to protect free speech.

            Flip it on its hea

            • When speech crosses into conduct ...

              You seem to find this quote redeeming, but again I see it as an acceptance of hate speech. And like I quoted, the question included an explicit mention of violence, not implied or not-implied depending on how "from the river to the sea" is interpreted. The interpretation of Stefanik is clear, by the explicit part, but Gay could have addressed that instead. She didn't, so no, she doesn't pass go, but gets to leave.

              As for your protection of free speech, you don't have a

              • I'm not sure "redeeming" is quite the right, and I don't personally agree with everything Gay said (nor do I think she said everything particularly well), but, as the saying goes, I'll defend her right to say it. The question was a trap and Gay walked into. Nuance is lost when politicians set up traps.

                Europeans and Americans have, traditionally, had very different views on "hate speech." I think we're much closer now than we were even 20 years ago.

                I said something like this in another post, but for me, the

                • Okay, good, I think we're mostly in agreement. Regarding A and B, I think that people are mostly condoning a yes to C: are IDF allowed to get back at Hamas terrorists? Because who are fighting IDF after, and who are fighting Palestinians after? In my view, that's what's the big difference regarding what people find acceptable speech.
          • You didn't read hard enough.
            Stefanik begs the question, and makes it a trap.

            will admissions offers be rescinded or any disciplinary action be taken against students or applicants who say from the river to the sea or intifadaadvocating for the murder of Jews?

            Those slogans are not calling for the murder of Jews any more than "Give me liberty or Give me death" was calling for the murder of Brits.

            We can all play this game- and that's the problem. I can pick some slogan, like "Make America Great Again", and say it calls for the murder of liberals.

    • part of a class action

      And what? Make a group of lawyers rich? No thanks.

      • Sure buddy, and how exactly would you propose that any group of people harmed by a wealthy organization, with nearly limitless access to lawyers and judges, seek recompense?

        Frankly speaking, corporations that profit from harming their customers have been the ones pushing to eliminate class action lawsuits, and propagandizing against civil recovery for the damages that they have done

        Oh my, you watched a EpochTV youtube feeding you full of bullshit, and now you are White Knighting for corporations

        What a rube

        • Sure buddy, and how exactly would you propose that any group of people harmed by a wealthy organization, with nearly limitless access to lawyers and judges, seek recompense?

          The only thing I can come up with is violence. Which is why I shouldn't be in charge of things.
          I also would like to know how any corp has been punished by paying a nominal fee and admitting no fault. I want to know who has been helped or save by the pittance they get after the lawyers take their cut. That if they get anything. They prolly will end with a coupon.

          So, I don't think this will work. Like the 1,000,000 other times it has been attempted and failed.
          Sure, maybe 1,000,001 will be the one that wil

        • Sure buddy, and how exactly would you propose that any group of people harmed by a wealthy organization, with nearly limitless access to lawyers and judges, seek recompense?

          Frankly speaking, corporations that profit from harming their customers have been the ones pushing to eliminate class action lawsuits, and propagandizing against civil recovery for the damages that they have done

          Oh my, you watched a EpochTV youtube feeding you full of bullshit, and now you are White Knighting for corporations

          What a rube

          In a case like this, I think a class action may be warranted, but I have yet to hear of any class action where more than a few dollars at most make it to the people most affected. In cases of this type of fraud causing this much damage? I'd much rather our government actually do one of it's primary jobs and serve the public good by starting criminal proceedings. We don't have a fitting punishment for corporations/schools/larger business related organizations now, but it's not like we can't come up with some

        • Sure buddy, and how exactly would you propose that any group of people harmed by a wealthy organization, with nearly limitless access to lawyers and judges, seek recompense?

          True, but class action lawsuits benefit the corporation. They end up paying much less than they would if they had to deal with each litigant separately.

          There's no good answer it's just stacked against the little guy.

          • They only benefit the corporation if damages are too low. When the corporation gets too big, that happens. Maybe increase damages proportional to the # of claimants, or reduce that percentage that can go to the lawyers.

            But if you hurt them too much, a lot of people, or all of them, could lose their jobs. Or everyone will be suing over nothing, and HR departments will become even more ridiculous.

            What exact system do you propose? A purge? Not sure we'd win that system, either!

      • It's more about hurting the bastards.

        • I am sure they feel real bad in their many mansion and luxury cars.
          • Well, sure, but I'm pretty fucking sure all assholes who get sued don't have mansions and luxury cars and can easily lose. Otherwise, they would never defend themselves. Are you really trying to argue that people should never sue?

            Oh, you were just being a total fucking asshole, yourself?

    • Re:Haaa Vaaaahd? (Score:5, Insightful)

      by hey! ( 33014 ) on Wednesday January 24, 2024 @05:22PM (#64185853) Homepage Journal

      Is this the same Harvard that holds almost $50 BILLION dollars in their endowment?

      No, this is Dana Farber, a large teaching hospital that is institutionally independent from Harvard College, but is affiliated with (i.e. trains students from) Harvard Medical School -- as are about eight other major Boston area hospitals. It's roughly analogous to your local vocational high school having an arrangment with some local car repair shops to help train students and provide internships.

  • by Hadlock ( 143607 ) on Wednesday January 24, 2024 @02:20PM (#64185385) Homepage Journal

    It's remarkably easy to pull an entire researcher's catalog of work, then use AI to cross reference it against all of (researcher's language here, probably english) scihub looking for plagiarism now. 10-40 hours per researcher. No surprise the people at the top cheated their way there.

    • Re: (Score:3, Interesting)

      by OffTheLip ( 636691 )
      It's ironic that technology made it possible for "people at the top cheated their way there" and technology will now expose them.
  • by wakeboarder ( 2695839 ) on Wednesday January 24, 2024 @02:22PM (#64185395)
    It does no one justice to lie and definitely not to yourself or organization. Yeah, it can be grey sometimes, don't do it. Ever.
    • Re:Tell the truth (Score:5, Insightful)

      by quonset ( 4839537 ) on Wednesday January 24, 2024 @06:35PM (#64186021)

      It does no one justice to lie and definitely not to yourself or organization. Yeah, it can be grey sometimes, don't do it. Ever.

      And yet, we have roughly half the country cheering a makeup wearing lying adulterer who wears lifts in his shoes.

    • by gweihir ( 88907 )

      That would be a good idea and it is the only way to actually advance your own personality (not your status or position). Most people cannot do it though.

      • I think most people were not taught to tell the truth, most everyone has the capability.
        • by gweihir ( 88907 )

          That is unclear. What is clear is that the average person lies daily and hence expects (often correctly) that others lie routinely too.

          I don't. I find it detrimal to understanding reality. As soon as you start lying to others, you are prone to lying to yourself as well. And that is not good at all.

  • One of the first things they taught us in college (a party school) orientation is that public urination is no joke.

  • by mosch ( 204 ) on Wednesday January 24, 2024 @02:38PM (#64185471) Homepage
    Great work by the investigators here! I enjoyed reading through the specific examples [forbetterscience.com] they found. There are a few that looked like people making mistakes with matplotlib and not catching it; a bunch that looked like people deliberately filling in missing sequence info with other data; and a few that are just baffling (little possibility it was a mistake; but also no obvious reason to fake that specific data). A bit of a shitshow, and clearly unacceptable. I mostly hope that this nonsense hasn't negatively impacted too much research and progress, and that the professional repercussions are appropriate.
    • At a certain point the fairly-incestuous process of peer-review starts to appear as foolish as letting Boeing inspect its own planes.

  • by Fons_de_spons ( 1311177 ) on Wednesday January 24, 2024 @03:15PM (#64185587)
    Had a colleague who's kid had cancer. He was telling that they occasionally would change or adapt the treatment protocol based on "new research". I hope these papers were not part of that.
    Academics urgently need to look into the mirror and objectively note what they observe. They probably have a course on that.
  • by Moof123 ( 1292134 ) on Wednesday January 24, 2024 @03:24PM (#64185605)

    A couple worthy podcasts from Freakonomis Radio that dig into this:
    Why Is There So Much Fraud in Academia?
    Can Academic Fraud Be Stopped?

    Roughly speaking we have an incentive system around "Publish or Perish" that makes honesty much less profitable than fraud. Fraud itself is too simple of a term when it comes to things like P-hacking. Until you can have a good career without becoming a paper mill, the problems of low quality and fraudulent academic papers will persist.

    • It’s quite possible to have a GOOD research/academic career without being a paper-mill or cheating. The issue is what’s required to have a TOP-TIER research/academic career. Those top spots are the equivalent of top professional basketball positions - for every spot, there are a thousand elites competing for it. It’s nowhere near enough to be in the top 0.1%. You need to beat out a thousand OTHER top-0.1 percenters.

      Top-shelf research and academics in the US is overcompetitive. Competit
  • We're kind of in an era where quoted science is open to suspicion and research results can't be trusted either.

    Frankly I doubted the Harvard report about levitating goats that quoted Einstein as saying gravity is just an illusion of small minds and then cited physicist Indiana Jones.

  • People cheat when it makes sense for them to cheat. I used to work with a PhD from Harvard, he would cherry pick data to tell any story he wanted. The company needed his projects to work and needed to show customers data, he needed to produce the right documents whether it matched reality or not. Similar to the Theranos situation actually.

  • And this just Harvard. Add in other big name universities and this number could get huge.

  • My very first university chemistry class began with the prof cheating. He had an experiment where to get the correct result he had to weigh some compound to an accuracy of 1 in 10,000. He showed us the fancy scale with the glass enclosure to get the measurement so accurate and then proceed to do the experiments and all the math on the board and then got the predetermined result. The problem was the buoyancy of the materials in air will give an error of just under 1 in 1000. There was no possible way the

"Confound these ancestors.... They've stolen our best ideas!" - Ben Jonson

Working...