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Science

RNA Has Been Recovered From an Extinct Species For the First Time (phys.org) 38

An anonymous reader quotes a report from Phys.Org: A new study shows the isolation and sequencing of more than a century-old RNA molecules from a Tasmanian tiger specimen preserved at room temperature in a museum collection. This resulted in the reconstruction of skin and skeletal muscle transcriptomes from an extinct species for the first time. The researchers note that their findings have relevant implications for international efforts to resurrect extinct species, including both the Tasmanian tiger and the wooly mammoth, as well as for studying pandemic RNA viruses. The findings have been published in the journal Genome Research.
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RNA Has Been Recovered From an Extinct Species For the First Time

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  • Nature findsâ" uhâ" a way.
    • by Anonymous Coward

      Nature findsâ" uhâ" a way.

      So how's that iPhone working out again?

    • In this case its a species they we did drive to extinction (at least a little faster - they probably were heading that direction anyways but we certainly sped up the process), so it'd be great if nature DID find a way in this case.

      We do apparently have quite a few DNA samples of these animals though so if we can ever get good cloning capabilities it would be a prime candidate to ressurect.

  • Was supposed to be a cautionary tale, not a manual.
    • by Anonymous Coward
      Oh come on, this is Slashdot, you should be welcoming our old-but-new-again Tasmanian Tiger Overlords with enthusiasm.
  • It's not like they recovered RNA from a species that went extinct 10s of thousands of years ago.
  • Just like anything from the Australian area.

    • by mjwx ( 966435 )

      Just like anything from the Australian area.

      And remember, this one was too weak to survive that.

      In Tasmania no less, the most sedate part.

  • Thatâ(TM)s a LOT of effort just so that a few game hunters can kill them to extinction again. You think our species can be responsible stewards of something like that?
    • Yes, they might be... in a protected national park reserve where hunting was disallowed.

      The extinction of Thylacine is something Tasmanians feel a sense of loss that their ancestors lived in less enlightened colonial times with bounties put on a 'pest' species. The animal features on various logos and mascots throughout the state.

      One can visit conservation reserves with not for profit breeding programs on the island for threatened marsupial species such as Tasmanian devils and quolls - cute little buggers b

  • I thought RNA is inherently unstable and survives for mere minutes before it breaks apart. How did we extract 100-year-old RNA stored at room temperature?

  • by nucrash ( 549705 ) on Wednesday September 20, 2023 @10:46AM (#63863074)

    I am still behind the idea of trying to bring back smaller species that had extinctions over the last century. While I would love to see a Wooly Mammoth, Tasmanian Tiger is far more realistic.

    That being said, there are some groups working on trying to restore the passenger pigeon. I hope they are more successful as they are smaller and likely less difficult to get started.

  • This pioneering study in paleogenomics offers fascinating insights into gene expression in an extinct species, shedding light on the biology of the Tasmanian tiger. The ability to extract and analyze historical RNA opens new doors for understanding the genetics of ancient organisms and their ecological adaptations. These findings have exciting implications for future research in the field of paleogenomics.

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