Scientists Created Male and Female Cells From a Single Person 131
An anonymous reader quotes a report from Scientific American: Most people have two sex chromosomes, either two X's or an X and a Y, which give rise to female or male biological attributes on a spectrum. Studies suggest these chromosomes also have much broader effects, contributing to processes that include immune system function, neuronal development, disease susceptibility and reactions to drugs. But scrutinizing the specific role of X and Y chromosomes is challenging. With current tools, it is difficult to disentangle the effects of genes versus hormones, for example. Now scientists have devised a tool that could overcome this obstacle -- by generating XX and XY cells from a single person for the first time. This unique set of cells could help researchers tackle long-standing questions about how sex chromosomes affect disease and the role they play in early development.
Benjamin Reubinoff, a professor of obstetrics and gynecology at the Hadassah Medical Center in Israel, and his team began the project to overcome barriers facing investigations of sex differences in humans. Currently there are two major ones, according to Reubinoff: the difficulty of separating chromosomal and hormonal effects and the inability to pinpoint the effects of X and Y chromosomes while ruling out contributions from the rest of a person's genetic makeup. "The main reason for doing this study was the lack of a good model to study differences between males and females in humans," Reubinoff says. "There have been animal models, but a model in humans was not available." To create such a model, Reubinoff, his former M.D. and Ph.D. student Ithai Waldhorn and their colleagues first obtained white blood cells previously collected from a person with Klinefelter syndrome, a condition in which male individuals are born with an extra X chromosome. The cells came from the repositories of the Coriell Institute for Medical Research, where people donate samples for use in a wide range of biomedical research projects. The donor had a rare "mosaic" form of the condition, in which some of their cells had three sex chromosomes (XXY), some had two X chromosomes, and some had one X and one Y. The researchers reprogrammed all three cell types into induced pluripotent stem cells, which have the capacity to self-renew and to develop into neurons, muscle cells or other cell types.
Ultimately the team generated XX and XY cells that -- apart from their sex chromosomes -- were genetically identical. The researchers then conducted a series of experiments replicating findings from prior studies with other models. For example, they confirmed previously reported differences in genes that were turned on in XX or XY cells. They also coaxed their stem cells to develop into immature versions of neurons and found evidence of previously reported sex differences in early neural development. "It was reassuring to see that the model really shows differences between the sexes that were reported from other systems," Reubinoff says. The findings were published last month in Stem Cell Reports. "This is a very well-designed study that validates the notion that sex differences start early in development -- and that they depend on the sex chromosomes because that's the only thing that can account for those differences," says Nora Engel, a professor of cancer and cell biology at Temple University.
Benjamin Reubinoff, a professor of obstetrics and gynecology at the Hadassah Medical Center in Israel, and his team began the project to overcome barriers facing investigations of sex differences in humans. Currently there are two major ones, according to Reubinoff: the difficulty of separating chromosomal and hormonal effects and the inability to pinpoint the effects of X and Y chromosomes while ruling out contributions from the rest of a person's genetic makeup. "The main reason for doing this study was the lack of a good model to study differences between males and females in humans," Reubinoff says. "There have been animal models, but a model in humans was not available." To create such a model, Reubinoff, his former M.D. and Ph.D. student Ithai Waldhorn and their colleagues first obtained white blood cells previously collected from a person with Klinefelter syndrome, a condition in which male individuals are born with an extra X chromosome. The cells came from the repositories of the Coriell Institute for Medical Research, where people donate samples for use in a wide range of biomedical research projects. The donor had a rare "mosaic" form of the condition, in which some of their cells had three sex chromosomes (XXY), some had two X chromosomes, and some had one X and one Y. The researchers reprogrammed all three cell types into induced pluripotent stem cells, which have the capacity to self-renew and to develop into neurons, muscle cells or other cell types.
Ultimately the team generated XX and XY cells that -- apart from their sex chromosomes -- were genetically identical. The researchers then conducted a series of experiments replicating findings from prior studies with other models. For example, they confirmed previously reported differences in genes that were turned on in XX or XY cells. They also coaxed their stem cells to develop into immature versions of neurons and found evidence of previously reported sex differences in early neural development. "It was reassuring to see that the model really shows differences between the sexes that were reported from other systems," Reubinoff says. The findings were published last month in Stem Cell Reports. "This is a very well-designed study that validates the notion that sex differences start early in development -- and that they depend on the sex chromosomes because that's the only thing that can account for those differences," says Nora Engel, a professor of cancer and cell biology at Temple University.
Coming up next: "I'm my own grandpa" (Score:3)
Re: Coming up next: "I'm my own grandpa" (Score:4, Funny)
This does give more consideration to the term: "go f yourself!"
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Re: Coming up next: "I'm my own grandpa" (Score:3)
Lazarus Long.
"Time enough for Love"
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He certainly seems confused one way or the other....
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If you're going to enter Heinlein into the case, the story to consider is "All You Zombies".
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If you're going to enter Heinlein into the case, the story to consider is "All You Zombies".
Ask and you shall receive [emilkirkegaard.dk] (pdf).
Except with Androgen Insensitivity Syndrome (Score:2)
Most people have two sex chromosomes, either two X's or an X and a Y, which give rise to female or male biological attributes on a spectrum.
Unless they're not sensitive to androgen hormones for whatever reason.
Re:Except with Androgen Insensitivity Syndrome (Score:4, Informative)
Which is pretty rare. Estimates are 2 to 5 per 100,000, or 0.005% of all males are completely insensitive to androgen with partial insensitivy estimated at the same rate. That means there's about 400,000 people globally (out of 8 billion) who are affected by this. I think we can call this an anomaly, or "edge case".
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0.005% of all males are completely insensitive to androgen
I would think that the percentage is 0%, because people completely insensitive to androgen are virtually always assigned female gender at birth.
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I can just imagine the conversation at the Ob/Gyn:
Please it down, Madam, I'm going to tell you something surprising. You have male chromosomes and there are some male gonads inside of you as well. Hence, you're actually a man. We've already notified the police and your new driver license is on its way. Are you feeling okay, Mister?
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It's exactly what the anti-trans movement is about. If you're XY, you're a man.
Unless they have a genetic testing kit, they're going to have to go with official documentation. If the birth certificate says female, they're going to have to accept it, even if they think to themselves "that used to be a dude." And vice versa.
More and more places are issuing new birth certificates that make no mention of any previous sex, so good luck trying to prove they used to be the opposite sex in court.
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And then it turns out it was actually a big clit. Works the other way sometimes as well, we'll surgically reduce that huge clit which was actually a dick.
As the summary says, it is a spectrum and those in the middle often have to be assigned one sex or the other and sometimes the Doctors get it wrong.
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The important thing here is that they shouldn't be disadvantaged or discriminated against for that condition. Much smaller and much larger groups have been treated badly in the past.
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It should be noted that a quite small minority - less than 0.5% of people - have one or no legs. Is it ok to not accommodate that variation because it's rare?
Re:Except with Androgen Insensitivity Syndrome (Score:4, Insightful)
No, but it would also be wrong to try and alter society to adapt to 0.005% of the population
Depends on the adaptation. The the adaptation is to not be an utter arsehole and discriminate against them, not discriminate against them and etc, then no it is not wrong to alter society to adapt to them. Because a society that is prepared to hurt 0.005% just for kicks doesn't stop there. They'll happily hurt lots of smaller and larger groups for different supposed reasons.
Keep going down that road and you'll end up banning keyboards and steering wheels because on rare occasions children are born without arms.
I wonder if you'll get the "stupidest post on Slashdot today" prize?
Re: Except with Androgen Insensitivity Syndrome (Score:2)
It depends on both the burden to society and the percentage affected. For such a small percentage, adaptations should be so minor as to be unnoticed by anybody but the tiny percentage benefiting from them. Adding braille to traffic lights, and textured paving at crossings strikes an extra excellent balance. Requiring new language and social conventions be adopted by everybody would be entirely unreasonable.
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How do you get from "accommodate" to "make things unusable for everyone"?
In the specific case we are talking about, the accommodation is "don't be an arsehole to that person". Is that too much to ask?
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Why should humanity be "defined", and society ordered, based merely on chromosomes?
AIS is just one genetic condition. As a sum total of genetic and foetal development conditions, there are plenty of others that show the sex chromosomes are not a good way to define humanity, or order society with.
I care only about the science, with all its statistically dependent certainties, not pseudo-science that ignores inconvenient edge-cases just so you can f
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XXY (Score:2)
Would that be the definition of non-binary?
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So still quite binary, no matter how many bits you use.
You need to add a Z
Z = SQRT(-1)
Then you can start getting all those weird imaginary genders.
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By that logic, every (whole) number is binary.
So, clone myself and self-procreate? (Score:2)
Seems like a winning strategy. Lmfao
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Seems like a winning strategy. Lmfao
Only until your offspring starts to learn about the downsides of inbreeding. But then again, this did not keep "royals" from practicing this for centuries.
I will finally get to sleep with myself (Score:3)
And give myself the hardest pounding in history because I am so fâ(TM)ing hot.
The Clone Song by Isaac Asimov (Score:5, Funny)
First two verses to the tune of Home On The Range
Oh, give me a clone
Of my own flesh and bone
With its Y chromosome changed to X.
And after it's grown,
Then my own little clone
Will be of the opposite sex.
Clone, clone of my own,
With its Y chromosome changed to X.
And when I'm alone
With my own little clone
We will both think of nothing but sex.
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Mozaic and Chimerism (Score:2)
https://en.wikipedia.org/wiki/... [wikipedia.org]
https://www.webmd.com/children... [webmd.com]
Required comment (Score:2)
On a spectrum... (Score:3, Insightful)
Barring unusual mutations or diseases, XX or XY is a binary choice. There is no "spectrum". Biology doesn't care about political correctness.
Obviously, other developmental and psychological factors come into play, but physical biology is - again, barring genetic disease - either male or female.
Re:On a spectrum... (Score:5, Insightful)
Barring unusual mutations or diseases, XX or XY is a binary choice. There is no "spectrum".
Barring all the cases where it isn't binary, it's binary.
Barring all the cases where you're not a moron, you're a moron all the time.
Biology doesn't care about political correctness.
Quite so. Biology doesn't care about your political/religious group's desire to cram things into neat, human-shaped categories. Biology is astoundingly messy and unreasonably complex no matter how much your politics wish it was not so. But as you said, it is not politically correct.
Re:On a spectrum... (Score:4, Insightful)
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Re: On a spectrum... (Score:4, Interesting)
I didn't say any different, read what I wrote. Physical development is - barring genetic disease - a binary choice: XX or XY, female or male. I object to inserting the word "spectrum" just for political correctness.
Of course, my comment was immediately modded "troll".
Re: On a spectrum... (Score:4, Insightful)
Up to ~2% of people fall outside of the rigid binary outcomes "XX/XY -> Female/Male Physiology": https://en.wikipedia.org/wiki/... [wikipedia.org]
Saying that Physical Sex is on a spectrum (even a relatively narrow one) isn't being politically correct, it's being more accurate.
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And (except some nutcases) is denying that. But gender is not linked to your genes.
Your (biological) sex is.
This whole "gender and sex are different" thing is modern-day bullshit. What you are calling "gender" is just personality and a person's individual mix of traits associated with masculine and feminine. A feminine man is still a man, period. He could choose to change his appearance and mannerisms to outwardly present in a manner he thinks is consistent with being a woman, but he's still a man and nothing can change that.
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Thing is, it's not just a spectrum. it's a spectrum in more than two dimensions. Given that it's a reasonable linguistic choice to have male and female refer explicitly to the ability to generate sperm or ova. But there are also cases outside of that range. To pick one example some folks appear male but can't generate sperm. So you'd need another word to refer to them.
Really, it's a mare's nest. Language shouldn't have to handle that, and generally it's definitions are expected to be all that precise.
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Medicine disagrees with you in case of transexuals.
In case of transexuals the brain structure does not match the body. Most likely a development error during pregnancy.
And because we can't match the brain with the body, we match the body with the brain.
Also complete bullshit. What you have here is untreated mental illness. What will soon kill this unfortunate social contagion is the wave of lawsuits that have already started.
South Park is supposed to be a comedy but instead it is now a documentary:
https://youtu.be/-kZ2afCBpfY [youtu.be]
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Medicine disagrees with you in case of transexuals. In case of transexuals the brain structure does not match the body. Most likely a development error during pregnancy. And because we can't match the brain with the body, we match the body with the brain.
Also complete bullshit. What you have here is untreated mental illness. What will soon kill this unfortunate social contagion is the wave of lawsuits that have already started.
South Park is supposed to be a comedy but instead it is now a documentary: https://youtu.be/-kZ2afCBpfY [youtu.be]
Actually, not treating it leads to mental illness and attempted suicide. Changing sex fixes the problem and drops the suicide rate down to normal in most cases.
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Medicine disagrees with you in case of transexuals.
In case of transexuals the brain structure does not match the body. Most likely a development error during pregnancy.
And because we can't match the brain with the body, we match the body with the brain.
Also complete bullshit. What you have here is untreated mental illness. What will soon kill this unfortunate social contagion is the wave of lawsuits that have already started.
South Park is supposed to be a comedy but instead it is now a documentary:
https://youtu.be/-kZ2afCBpfY [youtu.be]
Actually, not treating it leads to mental illness and attempted suicide. Changing sex fixes the problem and drops the suicide rate down to normal in most cases.
More bullshit. Here, from the NIH: https://www.ncbi.nlm.nih.gov/p... [nih.gov]
Significant outcomes
- Suicide death risk in trans people did not increase over time.
- Suicide deaths occurred during every stage of transitioning.
- Suicide death risk is higher in trans people than in the general population
What you have here is a population of very troubled people who need mental health counseling and treatment to help them come to terms with the cause of their dysphoria. Surgery and drugs do not address the root cause, a
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No data were available for people on the waiting list for their first appointment.
Those on the waiting list are, by definition, the untreated. Haven't seen anyone.
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The study admit's it's flawed:
No data were available for people on the waiting list for their first appointment.
Those on the waiting list are, by definition, the untreated. Haven't seen anyone.
There is no difference between someone on the list and someone who has just popped off and arrived for their initial evaluation.
Either way they have yet to be treated. If anything they would be motivated to exaggerate their condition at their initial evaluation.
You should read or watch some detrans stories to get a sense of how these people are being pushed into life altering treatment that doesn't help them.
Benjamin Boyce has done some great interviews, they can be really heartbreaking.
This was a great in
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There's a HUGE difference between people who haven't even managed to get on the list (and are probably living a dual life or even not able to express themselves at any time because of hostility in the workplace, home, etc.) and those who are able to get on the list.
So don't talk about stuff you have no knowledge of. Your prejudices are showing.
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There's a HUGE difference between people who haven't even managed to get on the list (and are probably living a dual life or even not able to express themselves at any time because of hostility in the workplace, home, etc.) and those who are able to get on the list.
So don't talk about stuff you have no knowledge of. Your prejudices are showing.
Watch the video, that person definitely knows this subject well, he's had multiple surgeries and drugs. The link puts you right to where he says "I'm telling you they are experimenting on us, it's not cute, I'm so angry". Just 5 minutes, you might even learn something. It's a really good interview.
You moved the goal posts from what the study wrote "people on the waiting list were not included" to "people who haven't even managed to get on the list". The latter are a figment of your imagination, there is
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First, you can always find someone who isn't happy in ANY situation.
Second, I did not move the goal posts. I pointed out the conceptual basis of the study is totally flawed. That's not "moving the goalposts" - it's pointing out that the "study" is total crap.
The latter are a figment of your imagination, there is no way to determine anything about them as a group other than by projecting your own biases as to their thoughts and feelings and personal experiences. The alternative view is "The aren't on the list because they don't need to be".
Your alternate view is demonstrably full of crap. Just look at waiting times for "getting on the list" - and not just for gender issues - for any issues. For example, the average time for a diagnosis of fibromyalgia is 5 years. Because of social f
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First, you can always find someone who isn't happy in ANY situation.
Second, I did not move the goal posts. I pointed out the conceptual basis of the study is totally flawed. That's not "moving the goalposts" - it's pointing out that the "study" is total crap.
The latter are a figment of your imagination, there is no way to determine anything about them as a group other than by projecting your own biases as to their thoughts and feelings and personal experiences. The alternative view is "The aren't on the list because they don't need to be".
Your alternate view is demonstrably full of crap. Just look at waiting times for "getting on the list" - and not just for gender issues - for any issues. For example, the average time for a diagnosis of fibromyalgia is 5 years. Because of social factors, many people wait decades for a diagnosis of being trans.
You're the one doing the projecting of your own biases.
You moved the goalposts when you changed the wording. The point of the "alternate view" was that of course it's full of crap, just like yours is. We can't generalize about the mental state of an unknown group of people who haven't signed up for anything or been evaluated by anyone.
So, to summarize your position:
People with firsthand experience with the issues, the mental state, and the severe problems with transgender medicine can't teach you anything.
You can speak with authority on the mental state and
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The wording of the so-called "study" was bogus. It was obvious that it only selected the group that was actually in a position to receive treatment - ignoring everyone who wasn't.
That you fell for it isn't my fault, or my problem. But it caters to your specific prejudices, so you were disinclined to even think critically about it. Not a good look.
As I pointed out,
Your alternate view is demonstrably full of crap. Just look at waiting times for "getting on the list" - and not just for gender issues - for any issues. For example, the average time for a diagnosis of fibromyalgia is 5 years. Because of social factors, many people wait decades for a diagnosis of being trans.
You're the one doing the projecting of your own biases.
You ignore that completely - because your position is indefensible. All those people waiting 5 years to get a proper diagnosis so they can be
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You can speak with authority on the mental state and experiences of an unknown group of people.
No, that's what you're doing. It's why you had to look on youtube to confirm your bias - you don't know anyone from that group in real life. I do.
Oh, so you know someone in the group? In your own words "First, you can always find someone who isn't happy in ANY situation."
And knowing that one person or a few people doesn't qualify you to speak about the general population.
So believe what you want, makes no difference to me, and it wont make a difference to the juries in the wave of lawsuits that are coming.
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Gender is a social construct that is used to assign, among other things, word usage in language. In some languages every thing is either male or female. In others the division is male, female, neuter. "Der Fluss" is a river. It's of the masculine gender. "Das maidchen" is a girl, she's of the neuter gender.
The most important question was missed (Score:2)
Which bathrooms are they supposed to use? #desantis2024 /s
- offtopic - (Score:2)
I was hoping to find insight into the science described in TFS. It seems that every single comment is about some sort of social perception of people with gender irregularities. My bad, I forgot this is Slashdot.
They (Score:2)
Only works on people who self identify as 'they'.
Comment removed (Score:5, Interesting)
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OK, how about https://www.ncbi.nlm.nih.gov/p... [nih.gov] ?
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Grow up and accept the fact that biology literally isn't binary.
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Exactly. People fail to understand, or are willfully blind, to the fact that our traits as a human are defined by genetics and that genes, including the many that define gender-associated traits, have mutations and variations in activation levels. Gender traits really are a spectrum by any scientific analysis.
And yes, the right-wingers don't want to deal with anything that goes against their world view. They want to see the world in black and white because they can't process anything outside of that. It ove
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The only purpose of strictly defining male and female is to discriminate on the basis of it.
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Of course it means casting them out. Which bathroom or locker room are the "in-betweeners" supposed to use? People who naturally have both traits or diminished traits associated with gender. Which locker room/shower are they supposed to use?
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First off .. some women, that is woman by every definition, including being able to kids .. do have beards. Just google bearded women. What I am saying is smaller private stall areas instead of large locker rooms. As for sports .. instead of gender based sports just make the women's category based on having low testosterone levels since birth to adulthood. People who grew up with low testosterone levels could compete in such a category, alongside other categories. Just don't call it "women's" category if yo
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So, we redefine humanity because of a vanishingly rare and bizarre abnormality? I don't think so.
It's not redefining humanity. It's just demonstrating that the "definition" you're clinging to is wrong.
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It very much depends on your exact definition of man. Biology is not as neatly binary as some people seem to think.
Anyway, if someone is born with a disability we don't usually detract from their achievements if they involved medical treatment at some point. It's all just a question of where you draw the arbitrary line.
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If someone is born with a disability, should we bend over backwards to pretend their abnormality is in fact normal? Does having a flipped coin land on its edge mean we can't use flipping coins to produce a binary result?
Re:Haha (Score:4, Insightful)
If someone is born with a disability, should we bend over backwards to pretend their abnormality is in fact normal?
Frankly, yes. If you're spending any mental effort day-to-day on consideration of whether other people are "normal" you need to get a life and get your nose out of other people's business.
Does having a flipped coin land on its edge mean we can't use flipping coins to produce a binary result?
You've managed to make an an anti-point here. Sometimes the rare event happens and the coin lands on its edge. If you blindly plough forwards with bUt ItS nOt NoRmAl and refuse to accommodate that it may happen then you're stuck without either the heads or tails you need. A rational person would simply flip the coin and move on with their day. Gender obsessed loonies on the internet will instead post huge screeds about how it's not normal, and perverted and a danger to kids etc etc and why we have to be dicks to people and never get around to just flipping the coin again.
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Might I direct you to the article upon which you are commenting?
If someone is born with a disability, should we bend over backwards to pretend their abnormality is in fact normal? Does having a flipped coin land on its edge mean we can't use flipping coins to produce a binary result?
What are you being asked to do that you consider "bending over backward?" Would opening a door for a blind person be "bending over backward?" Is using a person's chosen pronouns "bending over backward?" (That last one, seriously, involves almost no physical effort at all. It's hard to see that as "bending over backward".)
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That's not man making a baby. That's man outsourcing making a baby to a set of external tools involving high-tech [...]
We've outsourced much of our digestion to what was once the highest the tech available (fire). We've been doing it so long we basically need tech for survival these days.
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When did Slashdot give up on the future? The id
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When did Slashdot give up on the future?
Slashdot has really swung to the anti-intellectualism and anti-expert mode of the right wing.
It's now filled with poseurs who think acting all cynical and above-it-all makes them wise. Someone needs to tell them the 90s are over, and that they're quite late to the "too cool for school" attitude.
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When did Slashdot give up on the future?
Slashdot has really swung to the anti-intellectualism and anti-expert mode of the right wing.
It's now filled with poseurs who think acting all cynical and above-it-all makes them wise. Someone needs to tell them the 90s are over, and that they're quite late to the "too cool for school" attitude.
Everyone judges according to themselves.
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Re:Haha (Score:5, Informative)
Not always, you can have a XY femalenesserson whose SRY gene is mutated. The SRY gene is the master controller (transcription factor) of male features. If that is sufficiently mutated along with a couple of other things. Reference: https://www.ncbi.nlm.nih.gov/p... [nih.gov]
Furthermore most XY people with Swyer syndrome can have a functional womb if given estrogen therapy. They usually cannot produce eggs though.
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*female presenting person (I really mutilated that one lol)
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Gender development is not as simple as you seem to think.
xy == boy.
Women with CAIS [wikipedia.org] would disagree.
Mutilating one into a womb equipped mom-boy doesn't change that.
XY men with PMDS [wikipedia.org] would disagree.
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It's not that simple. There's a species of rat (on a Japanese island?) that has lost it's Y chromosome, but still has male and female rats. There's bee a lot of speculation that people are headed the same (or a related) way. (Lots of denial, too. I've got no real opinion, except that unless civilization crashes that won't happen to the species because of "technological fixes". [Though it may happen to isolated pockets [again because of "technological fixes". But with civilization not crashing, that's g
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With most people those are 1 on 1, but not with all.
Re:lol accidentally admit there are two genders (Score:4, Insightful)
Re: lol accidentally admit there are two genders (Score:2)
What is the practical impact of getting this wrong? People misspell or mispronounce my name all the time based on the most common spelling or pronunciation in the region I am in.
Do I suffer any harm by being referred to using the wrong name? Yes, it might feel annoyed but it does me no harm. Nor is it malicious.
What practical difference would it make to adjust the English language around this? From my perspective, it makes no difference what you call someone until it has a real-life impact.
For example, when
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People misspell or mispronounce my name all the time based on the most common spelling or pronunciation in the region I am in.
Do I suffer any harm by being referred to using the wrong name? Yes, it might feel annoyed but it does me no harm. Nor is it malicious.
Imagine the state refused to issue you an ID with the correct spelling of your name, but would only issue ones with the common spelling. Imagine that you could only open bank accounts and get credit cards using the common, but incorrect spelling. Imagine having friends and family who consistently mispronounce your name, no matter how often you correct them. Imagine people regularly accusing you of lying about the spelling of your name for attention.
Imagine if you had compared being trans with something t
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FWIW, it should be quite possible to convert a woman's cells into sperm, and even to select for male or female sperm. It might even be in a lab right now, but just not published yet.
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WHOOPSIE you're either a man, a woman, or a science experiment
Why can't you identify as all three?
News flash - we're all experiments. That's what randomly combining genes does - creates a new generation of experiments. Unlike reproduction by fission, which basically gives you a clone of yourself if you're a single-celled thingee. Not much natural experimentation going on there, and the end results are hardly as varied or as interesting.
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Reported for currently unacceptable common sense.
You'll never be allowed in any universities grounds again.
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If you have to lie to support your point of view, why does it never occur to you that your point of view is flawed?
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I know, right? People actually believe that gender-fluid bullshit.
Personally, I'd be suspicious of any theory a sadistic pederast like John Money contrived to rationalize his sociopathic cruelty but I guess it lets some mentally ill people avoid seeking the help they need.
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So why lie about the events leading to the ejection of the Harvard president?
Anyway, I know you think you have made some sort of devastating argument by invoking John Money, but I'm guessing he's of interest to gender obsessives like you, because I have no idea who he is. Why are you so obsessed?
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So if someone identifies as the opposite sex, we now know that we can't change that sense of identity. Not accommodating it leads to messy suicides. And that's esta
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I wasn't lying, I thought (as many do) that the last-previous appearance of Mr Summers in the national news (his comments about women) had something to do with his rancorous subsequent year and rancorous departure.
I stand corrected, I see now it was a) general faculty discontent about him (which his comments certainly didn't improve) but mainly b) the issue with Schliefer.
Why did you assume it was a deliberate lie and not simply a mistake?
I'd edit my original comment (which was hardly meant as a deep analys
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I stand corrected, I see now it was a) general faculty discontent about him (which his comments certainly didn't improve) but mainly b) the issue with Schliefer.
Then please accept my apology.
Why did you assume it was a deliberate lie and not simply a mistake?
Same reason you assumed I knew who John Money is. Everyone on these threads assumes everyone else has an axe to grind especially with opinions stated with force. I still don't get your point about John Money.