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Medicine Biotech

Can This New Treatment Stop the Common Cold? (fortune.com) 67

"Researchers may have identified a compound that can stop some of the most common cold viruses, the rhinovirus, in its tracks, according to a new report published in the journal Nature." An anonymous reader quotes Fortune: The scientists' work is early-stage. But the mechanism it uses to tackle colds is striking. Developed at the Imperial College London, the molecule targets a protein in human cells that cold viruses use in order to replicate and conquer. By targeting this specific pathway, the compound could theoretically be used to thwart most viruses (and since it focuses on human proteins, it may not cause the virus to mutate its way away from danger)...

"The common cold is an inconvenience for most of us, but can cause serious complications in people with conditions like asthma and [chronic lung disease]," said lead researcher Ed Tate in a statement. "A drug like this could be extremely beneficial if given early in infection, and we are working on making a version that could be inhaled, so that it gets to the lungs quickly."

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Can This New Treatment Stop the Common Cold?

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  • by arth1 ( 260657 ) on Saturday May 19, 2018 @09:41AM (#56638494) Homepage Journal

    "A drug like this could be extremely beneficial if given early in infection, and we are working on making a version that could be inhaled, so that it gets to the lungs quickly."

    Just spray all the big cities with crop dusters. What could possibly go wrong?

    • Re:Solution (Score:4, Funny)

      by sizzzzlerz ( 714878 ) on Saturday May 19, 2018 @10:03AM (#56638560)

      Back in the 1980's, eradicating a fruit fly infestation here in California was all the rage. Towards that goal, then-Governor Jerry Brown backed a program to spray malathion from helicopters, at night, over the affected areas. When complaints rose over people being poisoned, they tried to minimize the dangers by pointing out how diluted the spray was. Brown's head of the program, B.T. Collins, on TV, drank a glass of the spray mixture. Literally. Something about proving how safe it was. It was totally worth it to see him, after drinking it, bending over and wretching, live on TV.

      • Brown's head of the program, B.T. Collins, on TV, drank a glass of the spray mixture.

        That reminds me of a British politician when Mad Cow disease was epidemic in England. He stuffed a hamburger into his own toddler's face live on TV, to show how "safe" Mad Cow British Beef was.

        I'd like to hear a follow-up on how the child turned out.

      • Are you sure you weren't watching Pitch Perfect?
  • by Anonymous Coward

    Clickbaity titles are clickbait. Asking your readers to supply the answer you're supposed to give yourself is very much clickbait.

  • by JoeyRox ( 2711699 ) on Saturday May 19, 2018 @09:57AM (#56638546)
    After which the virus will find another way to infiltrate human cells. It's hard to win a race against something that has a 200,000 year head start.
    • But we are getting better at it [wikipedia.org], which a couple completely eliminated and many more on their way to eradication.
      • We are very close on polio. It's holding on, mostly due to inaccessible areas acting as reservoirs, but those areas shrink each year. Making good progress on guinea worm too.

    • Perhaps, but it will not be easy. Evolution has been working on our immune-systems as well
    • if they other side doesn't know it's playing. Yeah, this is complicated stuff, but we've really only been seriously trying to solve these problems for about 100 years or so. Hell, it wasn't too long ago folks argued against the germ theory. Now, if we can just avoid blowing everything to hell for once and regressing back into primitive superstition...
  • by Anonymous Coward

    Whatch the anti-vaxer-like morons who'll soon claim that this causes autism. There will be lectures, a youtube channel, a patreon account, and they'll make a fortune once again with the stupidity of the general population.

  • No. (Score:5, Insightful)

    by Gravis Zero ( 934156 ) on Saturday May 19, 2018 @10:17AM (#56638592)

    How do people not know Mr. Betteridge by now?

    • by SeaFox ( 739806 )

      How do people not know Mr. Betteridge by now?

      Well you see, years ago, there was this crazy plan to spray a certain compound over towns to eradicate this common but fairly minor public health threat. But they didn't do enough testing of the compound or it's long-term health effects without going forward...

  • Mutate its way away from danger? How does that work? And what if I want that protein to do what is was made to do? And Frankenfish, whatever happened to them?
  • by i286NiNJA ( 2558547 ) on Saturday May 19, 2018 @10:21AM (#56638614) Journal

    Question headlines contribute to the normalization of clickbait and many people instantly distrust them
        Just tell us please

  • I'm in the Linus Pauling camp of ingesting what some people would consider massive amounts of vitamin C to prevent or ameliorate symptoms of viral ailments. I swear by it based on my own experience. Your mileage may vary and I'd recommend researching the issue before deciding if it's something you should try.

    And yes, I'm aware that some people consider him a quack but I'm not here to debate the issue, just sharing what has worked for me.

    • by Anonymous Coward


      And yes, I'm aware that some people consider him a quack but I'm not here to debate the issue, just sharing what has worked for me.

      This is an anti-science position. If we all took this "it worked for me" position, we'd still be using leaches, bloodletting, and drilling holes in our heads. We need evidence to support conclusions.

      • I would tend to agree with you had that been the only source of information I have, but it isn't.

        I'll give you two analogies and see if you can noodle out where I'm coming from. I'm guessing you probably can't, but here goes.
        * It is my experience that antibiotics are helpful to take in the case of bacterial infection.
        * It is my experience that after throwing a heavy object in the air it reaches a maximum height then reverses course and returns to earth.

        Aside from my own experience, I have other reasons to

  • by Anonymous Coward

    Could the common cold and influenza be eradicated if everyone on earth just spent a week quarantining themselves?

    Or do the viruses move among animal populations as well?

    • by arth1 ( 260657 )

      Could the common cold and influenza be eradicated if everyone on earth just spent a week quarantining themselves?

      Or do the viruses move among animal populations as well?

      That a couple of the biggest flu strains are called "bird flu", what do you think?

      A big problem is that many viral diseases are endemic to animal populations, and require minimal mutations that happen all the time[*] to jump to humans. They never survive long in humans, because they are too aggressive - both killing the host and being killed by the host is bad from the virus' perspective. Being able to infect and spread without doing much damage to the host is a much better survival mechanism, and what ha

      • In part due to the rapid reproduction cycle, and in part because viruses lack the DNA repair mechanisms that more advanced species have.

        And in part because when a host is simultaneously infected with two related viruses, the processes called "reassortment" can produce a new virus with genetic material from both "parent" strains. If the combination is, say, a particularly virulent toxin or toxic effect from one parent and an infection protein or protein-network component(s) that enable(s) infection of human

    • by mentil ( 1748130 )

      This was covered by Randall Monroe in his 'What If' series. Conclusion: immunocompromised people remain reservoirs of pathogens, since it takes longer than a week for them to eliminate the infection.
      We could probably quarantine those people longer, but that'd include the elderly and infants, and there are members of both groups that can't care for themselves for a few weeks. HIV-positive people might end up in permanent quarantine...

  • by slashmydots ( 2189826 ) on Saturday May 19, 2018 @11:04AM (#56638734)
    About 18 or so years ago they discovered that zinc prevents viruses from being able to attach to the cells along your mucous membranes and thus stops their ability to replicate. Immediately after, entire cities sold out of it and Zicam got rich. It actually does work.
  • My Mother is 75 years old and has never had a cold. These people should be poking and prodding her. And if she exists then surely she isn't the only person with this resistance out there.

  • Just "a" common cold. There are a lot of viruses that can cause the common cold, but as they are essentially identical in symptoms and treatment*, they all get lumped together.

    *ie, there isn't one.

  • Nothing wrong with the common cold, why muck about with dodgy ways to stop something that's harmless?

  • Bad idea IMO. We are symbiotic with our microbiome. Anything that indiscriminately kills the viruses that make up a small but important part thereof, will damage our health, far more than the cold virus possibly can. Same reason antibacterials are a bad idea (beyond that they also help to breed resistant pathogens). Also same reason why antibiotics/antivirals/antifungals in the food supply are a bad idea. It is being learned, slowly and gradually and with a lot of resistance from "mainstream" medicine

Avoid strange women and temporary variables.

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