Humans Choose Friends With Similar DNA 204
KentuckyFC writes "The study of social networks has long shown that people tend to pick friends who are similar to them — birds of a feather stick together (PDF). Now a study of the genomes of almost 2000 Americans has found that those who are friends also share remarkable genetic similarities. 'Pairs of friends are, on average, as genetically similar to one another as fourth cousins,' the study concludes. By contrast, strangers share few genetic similarities. The result seems to confirm a 30-year-old theory that a person's genes causes them to seek out circumstances that are compatible with their phenotype. If that's the case, then people with similar genes should end up in similar environments and so be more likely to become friends."
How dare you!? (Score:5, Funny)
How dare you insult my friends by comparing them to me!
Re:How dare you!? (Score:5, Funny)
How dare you insult my friends by comparing them to me!
I wouldn't have anyone like myself as a friend.
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I wouldn't have anyone like myself as a friend.
So...I take it you're not on speaking terms with yourself? That must suck, seeing as you probably won't get rid of yourself any time soon.
XENOPHILIA! (Score:2)
I'm stuck with this bastard, for now. Just wait til I die, though!
Seriously. My friends would not be very closely identified with each other - or me. Nor would my wife or children!
I believe that "genetic purity" is a code word for incest.
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Would that not be more troubling if you are on speaking terms with yourself? People would think you are insane!
But I *am* insane! Or at least seriously disordered. Now I wouldn't want to mislead people by trying to look normal, would I?
Re:How dare you!? (Score:5, Funny)
Or, as Groucho Marx once put it, "I refuse to join any club that would have me as a member."
Re:How dare you!? (Score:5, Interesting)
Groucho wasn't being self deprecating, he was mocking the anti-semitism of the time and how once he became famous, all these organizations that normally would never have considered letting someone Jewish join suddenly wanted him to become a member.
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"Hey babe, is this guy boring you? I'm from another planet!"
Similar areas? (Score:2, Interesting)
Was there a control for geographically similar area? If you live in certain areas like Appalachia, everyone you know is probably a fourth cousin. So of course your friends would be related to you.
hmm (Score:2)
Whatever the cause, the discovery that our friends are genetically similar to us has significant implications. “The subtle process of genetic sorting in human social relationships might have an important effect on a number of other biological and social processes,” say Christakis and Fowler.
For example, germs, viruses and even information may spread more (or less) easily amongst groups that share a particular genetic background.
So we evolved a tendency to monoculture, making us more vulnerable to disease? That would seem ... counterintuitive.
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There are often trade offs in adaptations. Sickle cell animia isn't great, but having part of those genes wards off malaria. More vulnerable to disease, but having people who are like us around might lead to more social benefit. Like if a father dies, another man might take over if the children are similar to him.
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> So we evolved a tendency to monoculture, making us more vulnerable to disease? ... counterintuitive.
> That would seem
Not really, only if taken out of context and to the extreme. The relation between friends is states as about the same as a "fourth cousin". A fair amount of mixing happens even amongst the children of a single pair of parents with 2 copies of up to 4 possibilites being selected for each gene in each individual... fourth cousins is still enough room for quite a bit of diversity.
Think o
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So we evolved a tendency to monoculture, making us more vulnerable to disease? That would seem ... counterintuitive.
Actually, the study says the opposite. When it comes to immune system function, we strongly prefer people with different genes.
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So we evolved a tendency to monoculture, making us more vulnerable to disease? That would seem ... counterintuitive.
Not necessarily. It could be a simple side effect of our internal program that makes us social animals instead of solitary. So then perhaps the effect on disease vulnerability doesn't have a detrimental evolutionary effect greater than the evolutionary benefits of forming tribes.
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Monoculture? Hardly. Fourth cousins would, on average share 1/32 of their genes....
2000 Wyoming (or Montana, or Nebraska) citizens (Score:3, Insightful)
I find this study to be extremely flawed, not to say elitist / racist.
Yes, rednecks who listen to country music and drink cheap beer and whisky like to have friends who are also rednecks who listen to country music and drink cheap beer and whisky.
If the study had been conducted with 2000 subjects from culturally diverse places, like NY or Tokyo, I'm sure the results would've been a lot diferent.
I was going to post AC, but fuck it, I got karma to burn...
Re:2000 Wyoming (or Montana, or Nebraska) citizens (Score:5, Interesting)
I find your comment to be the same. Assuming that people in the city are more sophisticated than "rednecks who listen to country music and drink cheap beer and whisky"? How is that not an elitist comment? Cultural bubbles can also exist within large urban areas. This is how you end up with a Little Italy, China Town, etc sections in each large city. There are others not so visually apparent, I'm just picking on commonly known ones who's existence I wouldn't have to argue about.
Re:2000 Wyoming (or Montana, or Nebraska) citizens (Score:5, Insightful)
I find this study to be extremely flawed, not to say elitist / racist.
Yes, people who fit a stereotype of those I dislike like to have friends who are similar.
If the study had been conducted with 2000 subjects from places with people like me, I'm sure the results would've been more comforting to me.
FTFY
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Uh, I'm a software engineer working in Iowa on avionics. Embedded hardware that's part of an OBOGS unit. It let's fighter pilots breath. I was born in Omaha Nebraska. I'm part of the local hackerspace, founded a fencing salle, and regularly go to a symphony. Crown Royal and Maker's Mark is about the cheapest whiskey I'll stomach. I prefer rock and techno. I work with Indians and Chinese (and a lot of old white guys). I am, in short, "from the city". In Iowa. Deal with it.
Damn straight you're burning karma.
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If the study had been conducted with 2000 subjects from culturally diverse places, like NY or Tokyo, I'm sure the results would've been a lot diferent.
It's worth noting here that the data used in the study comes not from Wyoming, but from the Framingham Heart Study [framinghamheartstudy.org] which apparently studies a few tens of thousands of people for cardiovascular disease over many decades. It's not a particularly ethnically diverse town so there's that going for you.
Personally, I think we'd find that there are different distinct friend-acquiring strategies out there. Picking people like you is still probably going to be the dominant one no matter how diverse the area you pi
Could it be something more basic? (Score:5, Interesting)
In a number of different memoirs from actors in the original Planet of the Apes, it was noted that people playing different types of apes always sat with each other at lunch. It was a bizarre granfalloon - baboons with baboons and orangs with orangs for no other reason than that they looked the same. And these were people that knew each other before the film.
People have a natural inclination to like people that look more like them whether it makes sense in modern society or not.
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Maybe it goes deeper than looks! That would really be cool.
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In a number of different memoirs from actors in the original Planet of the Apes, it was noted that people playing different types of apes always sat with each other at lunch. It was a bizarre granfalloon - baboons with baboons and orangs with orangs for no other reason than that they looked the same. And these were people that knew each other before the film.
People have a natural inclination to like people that look more like them whether it makes sense in modern society or not.
That doesn't make sense. A while ago, I had to with storing my clothes and getting dressed where there were no mirrors. I had no idea how badly I was mismatching clothes and colors.
The point is I had no idea what I looked like. How would I seek out similar people?
The different apes could have sat together for thousands of reasons. Something as small as a prelunch routine that gave the different apes even something small differently could result in them sitting together.
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And granfallooning is a powerful mathematical technique. Surely, you've heard of the four granfalloon theorem [wikipedia.org]? Or the more general property of graph granfallooning [wikipedia.org]? And there's the topological result that one can decompose in non-overlapping granfalloons the sphere finitely in such a way that one can construct two identical copies by putting back together the granfalloons in different ways.
except for the good friends that arent (Score:2)
yeah, people like to live in a comfort zone — but i've found that some of the best friends come from right out of that comfort zone..
2cents
jp
A man needs a little madness, or else he never dares to cut the rope and be free.
(Nikos Kazantzakis, Zorba the Greek)
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yeah, people like to live in a comfort zone — but i've found that some of the best friends come from right out of that comfort zone..
What about people who have a mix of genes from all over? Does that explain the wide genetic diversity amongst my friends, and how I like to hang out in diverse places with not much racism?
What is described here seems rather incestuous, like "all my friends are clones of me", like a bunch of Greys. I guess there are some people like that.
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I dont get how everyone on here keeps making the equation: genetics = race. Thats not what this is about.
I'm an engineer. Since I was a kid, I've loved to take things apart and put them back together. The closest friends I have in life are all from different parts of the world but they tend to be like me in that they also grew up taking things apart and putting them back together. So whatever gene-grouping is responsible for that behavior is probably shared by my friends from India, Russia and Sweden.
Geneti
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It's normal. (Score:5, Funny)
After all, many friends fuck their friends' wives, so after a couple of generations, they are all a happy family.
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To eliminate the possibility that the results are influenced by people tending to make friends with distant relatives, we use only the 907 friend pairs where kinship <= 0 (recall that kinship can be less than zero whe n unrelated individuals tend to have negatively correlated genotypes). This procedure ensures that pairs of friends in the GWAS are not actually biologically related at all.
Fourth cousins? (Score:4, Interesting)
If there are only six degrees of separation between you and just about everybody on earth, the classification "fourth cousin" probably covers a large part of the earth's population!
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You have a many more social connections than genetic connections. You only have two parents, being a fourth cousin means you share a great-great-great-grandfather and you have at most 2^5 = 32 of them or less if they've interbred. The world fertility rate is now on average 2.36 children, it'll be a rough approximation but each great-great-great-grandfather will have approximately 2.36^5 = ~73 descendants. That's ~32*~73 = ~2336 fourth cousins ignoring any overlap. Of course you'll have other close relatives
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Back in my college Medieval History class, our instructor explained to us that the "Speak now, or forever hold your peace" line in wedding ceremonies has its roots in a Catholic church prohibition at the time which disallowed marriages between sixth cousins or closer. If you knew that the couple were more closely related than that, then you piped up right there and put the kibosh on the arrangement.
But nearly everyone in England at that point was at least that closely related to each other, so the prohibit
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I should have figured that everybody (in this crows) would jump on the technical distinction between "degrees of separation" and biological cousins. Well, DUH! I guess i need to spell it out. The point was, we all have an awful lot of fourth cousins!
Has this been corrected for other factors... (Score:2)
... such as birthplace and race?
Race alone would account for a huge genetic difference, and people tend to be friends with people of their own race for all sorts of reasons that can be easily explained through psychology and sociology. You're also more likely to be at least distantly related to people who live in the same area as you do.
Re:Has this been corrected for other factors... (Score:4, Insightful)
Genome Based Social Network/Dating Services (Score:2)
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Choice of circumstance? (Score:5, Interesting)
I'm reminded of the Better Off Ted episode Get Happy [tvrage.com]
Linda suggests that Veridian let its employees have decorations in their company. Veronica agrees, but the company selects the decorations and assigns them to the employees. Linda discovers that she's suddenly a cat person, while other employees have cars, Green Bay Packers, or space decorations.
"Veridian Dynamics. Teamwork. It keeps our employees gruntled."
So which is it? (Score:2)
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However along with other outward physical traits those are the genetic differences we can judge just by seeing, and if we assume that the rest of the genetics are fairly evenly distributed it's going to be a pretty significant bias. Without doing a genetic test i can make a reasonable argument that statistically my asian friends are more likely to be more genetically different from me than my white friends.
I suppo
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Or are asians and white people far more closely related on a genetic level than i've previously been led to believe?
Actually, yes. There is far more human genetic diversity within the continent of African than in all the areas where human who migrated out of Africa settled. [wikipedia.org] The further away from Africa you get (in terms of prehistoric migration), the less genetic diversity there is.
Most of what people focus on in defining the "races" is superficial traits mostly distinguished by appearance. Beneath the surface, there's a lot more commonality, and there's a lot less variation in areas further removed from Africa.
All th
Let's see (Score:2)
More eugenics propaganda! (Score:3)
Nothing to see here, move along.
I'm sure that a few will claim "no, you are just anti-science" or some such but lets check a simple fact. 2000 genes were used in this study. What percentage of the human genome is this? Not only would this mean that "correlation == causation", but that correlation of 8.024e-6 (yes, that is a very small number) is the "normal".
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2000 genes were used in this study. What percentage of the human genome is this?
"A 2012 analysis of the human genome based on in vitro gene expression in multiple cell lines identified 20,687 protein-coding genes."
http://en.wikipedia.org/wiki/Human_genome [wikipedia.org]
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Thanks for the correction. This makes the analysis on 8.024e-5 which is still a very small percentage of our genes.
We share about 98% of our genes with chimpanzees, dude. It's not like any one of our many genes can be different, the vast majority are exactly the same. By contrast, the current theory that the homo sapiens first evolved in Africa is based on a study that looked at 1327 DNA markers. Are you going to claim that study is also flawed?
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Primarily, I am claiming that making psychological determinations by reviewing our DNA is a ludicrous prospect. Secondarily, claiming that we are 98% the same as chimpanzees is an absurd correlation used to dehumanize people, considering the length of DNA.
While we can figure out certain mechanics, human behavior and knowledge are trained. They are not in our DNA.
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Double fail! (Score:2)
This study fails on two counts: Americans are statistical outliers; the conclusion is fallacious due to poor understanding of causality.
For those for whom this is TL;DR -- Americans are the worst possible population to base any form of human study on (let alone a flawed study) - ref Solomon Asch's conclusion. The short summary @ neuroecology [wordpress.com] ; the longer discussion @ pacific standard [psmag.com].
My dog is my best friend (Score:2)
Does that mean I have canine DNA?
Now you will have to excuse me - I have some territory to mark
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Does that mean I have canine DNA?
No, but if your relationship develops into something more serious than just friendship, maybe your joint offspring will . . .
SubjectsForCommentsAreStupid (Score:2)
Sponge (Score:2)
My best friend's a sponge - we share 70% of the same genes.
This whole shared genetics thing ... (Score:2)
Re:Bull (Score:5, Insightful)
No kidding. I'm thinking that the majority of people live, breed and die within a few hundred miles of where they were born and this goes on generation after generation. One would expect a certain homogeneity in the range of genes within that population.
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No kidding. I'm thinking that the majority of people live, breed and die within a few hundred miles of where they were born and this goes on generation after generation. One would expect a certain homogeneity in the range of genes within that population.
I live 2500+ miles from where I was born and some of my best enemies are humans.
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No kidding. I'm thinking that the majority of people live, breed and die within a few hundred miles of where they were born and this goes on generation after generation. One would expect a certain homogeneity in the range of genes within that population.
So you're saying that *all* your neighbors are your friends?
Re:Bull (Score:4, Insightful)
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Most cities around the world you will find that people with the same ethnic background are far more likely to become friends than if they have different backgrounds. People in the same social class are more likely to interact and become friends, even in cities. New York is a huge city and yet it has very distinct neighborhoods, and in many ways is very parochial compared to smaller towns.
No one but you said people "always" pick those near their place of birth.
Nothing in this study said that ALL yo
Friend zoning (Score:2)
If this behavioural trait is true, it may explain the "friend zoning" that women do in an evolutionary way. The best of friends (and the closest in genetics) rarely get laid because it would be a from of inbreeding. If organisms have a way to detect and closely associate with genetically similar individuals, it wouldn't be a stretch that mating strategies would evolve to seek individuals from outside this close group.
And then again, there's the women who like to make their rounds with entire circles of fr
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What's so difficult to understand? You can't comprehend that some women like sex as much as men?
I've never met a woman who knows what a proper orgasm is who didn't love sex as well. plenty of women who haven't been properly pleasures don't like it, sure. Not ones who have had a good orgasm though.
Perhaps your view is skewed do to your own issues. And before you respond, just because you can jackhammer her for an hour, doesn't mean any part of it was good. 9 out of 10 women would rather have a good quic
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You're reading too much into a small joke. Your comments also likely also say more about yourself than me. :-)
Re:Bull (Score:4, Interesting)
For example, if you're white and live in the bronx, and significantly less than half of your local friends are hispanic [wikipedia.org], then obviously race factors into who you make friends with in some way. You could do the same thing with genetic markers.
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And why do strangers become friends? Sometimes it's from finding they have common interests. If they find out they're from the same region of the country they can become friends over that, even if they're currently living a thousand miles away from home. Friends form also from people at the same college or university and those are regional as well, even big name colleges tend to have a majority of students coming from the same state or region (ie, Harvard undoubtedly has far more students from New Englan
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That doesn't disprove anything. This is about people in general, not about one person in particular, and it never said you will become friends with everyone close to you. You may be not be friends with 200 of your neighbors but at the same time you're not friends with 4 million people from China.
This is statistics too. No one said that this was true for every single human being. If someone says that more people voted for Obama than for Romney, stepping forward to say "that's not true, I voted for Romney
AC, party of one (Score:5, Informative)
I've lived around the world and have a variety of friends.
Well neat. You alone must be a representative sample set of humanity that dwarfs this mere 1932 person sample group for statistical relevance. Thank goodness you know more about statistics than people doing a population study!
I'm assuming these 2000 individuals for the study were in environments that just happened to have similar genes around them.
Actually, if you read the study (OMG! I must be new here!), then you'll see that they address this point:
"There are (at least) four possible reasons that friends may exhibit homophily in their genotypes. First, correlation in genotypes may be a trivial by-product of the tendency of people to make friends with geographically proximate or ethnoracially similar individuals who also tend to share the same ancestry. Thus, it is important to use strict controls for population stratification in tests of genetic correlation (below, we rely on the widely used principal components method to control for ancestry). [...] Third, people may actively choose particular environments, and, in those environments, they may be more likely to encounter people with similar phenotypes influenced by specific genotypes. If people then choose friends from within these environments (even at random), it would tend to generate correlated genotypes."
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"To eliminate the possibility that the results are influenced by people tending to make friends with distant relatives, we use only the 907 friend pairs where kinship â 0 (recall that kinship can be less than zero when unrelated individuals tend to have negatively correlated genotypes)." (ed: They do the same with 907 stranger pairs.)
In the end, they find that people prefer friends that share genes for the same sense of smell and the same linoleic acid metabolism. We also strongly prefer people with different genotypes for immune system function. While there are hundreds more homophilic and heterophilic gene correlations, those were the three that were most over-represented between people. There are many other genes that friends share, but most of those vary from pair to pair of people and are either idiosyncratic preferences or possibly just coincidences. Those three genes are not.
It's pretty well known that human select their lovers in part by smell. It's interesting that we pick our friends too that way. The paper gives a few good theories for why that's true (based on older research) and also does so for the immune system. The linoleic acid thing seems to have baffled them a bit, though they make a stab at explaining it as possibly being related to food safety and keeping the community on the same page about what's good to eat.
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They did study a relatively cosy community [wikipedia.org], which was predominantly white. They removed as many families and evidence of distantly-related friends as they could using the Manichaikul et al. 2010 kinship metric [nih.gov], which has been cited 34 times (a fairly good number of hits for a two-year interval.)
The upshot of this study, in my opinion, is that the things that make people compatible friends happen to be reflected (to a degree) in certain markers in the genome. It doesn't necessarily indicate anything about ra
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It sounds to me like they shot an arrow into the side of a barn, then drew a bulls-eye around it, afterwards.
Re:Bull (Score:4, Interesting)
The suspicion that part of social compatibility can be explained through superficial genetic traits has been explored before. The bibliography on page 21 of the totally free and unpaywalled arxiv PDF [arxiv.org] has a few citations that seem pretty similar.
That being said, I'm not so sure about some of their conclusions; they make it sound like there are purely mechanistic reasons why we seek out the friends we do. Consider the following:
The implications of the finding regarding homophily on genes related to linoleic acid metabolism are unclear. Linoleic acid is a precursor for substances involved in a broad range of important bodily processes (ranging from adipocyte function to bone formation to the regulation of gene expression) (42), and the component genes in the pathway are related to the metabolism of cholesterol, steroids, and various ingested substances, though it is intriguing that linoleic acid compounds might be used by moths as pheromones (43). Possibly, this pathway is related to the restrained consumption or the specific metabolism of various foodstuffs, traits for which homophily may be advantageous and heterophily self-injurious.
Personally, I think this is patently absurd and that there is no way this could influence personality or human behaviour. It seems to me to be more likely that the linoleic acid genes either have some wildly obscure indirect effect on personality that we can detect, or that they're simply inherited by chance with something that does.
It would have been wonderful if people here actually bothered to RTFA so we could argue about whether or not biochemically-inclined sociologists are out to destroy civilization by being too narrow-minded. On the plus side, this is a biology paper that was submitted to Arxiv, which means that it probably is having trouble getting into a major journal (i.e. it's very possibly being regarded as crap by journal editors due to its weird conclusions.)
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Personally, I think this is patently absurd and that there is no way this could influence personality or human behaviour. It seems to me to be more likely that the linoleic acid genes either have some wildly obscure indirect effect on personality that we can detect, or that they're simply inherited by chance with something that does.
I agree, and this paper to me continues a trend of portraying humans as nothing more than organic machines. Emotions and morality are often portrayed by the same publishers as malfunctions in the organic machine which must be mended by science (I did not detect that in TFA, just pointing out that it is a regular occurrence).
It should be obvious that we are not simply machines. Appeals to intellect are used to convince people that rational thought is incorrect.
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I don't agree that we are simply machines. Humans have incredible capacity for learning and emotion. Our psychological behavior has very little to do with the mechanics, and everything to do with what we learn and see in society as well as our social standing. We can learn that learning is fun, or we can learn that learning is horrible. We can learn courtesy, or learn to be barbaric. We can learn that lies are good, or learn that lies are bad (and this is complex, because we learn loads of grey area in
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But there are mechanisms for learning; mechanisms we know must exist and, to some extent, even understand. The subtleties in them form the foundation of who we are when we are conceived, and interplay with our experiences as life continues. They are the tie-breakers that prevent us from being completely at the mercy of our situations, and what ties us to our parents even if we have not met them.
What these people do is claim there is nothing more, and it is obvious they have no knowledge of cognitive science
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If there were simply a mechanism for learning, we would be able to determine algorithmically how to operate that mechanism withing defined parameters, and control for variables, to get predictable results with near-uniform outcome.
Please excuse my French, but "No fucking way."
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We are as certain of the physical laws of the universe as our sensory perception and intellectual tools for extrapolation - this includes maths - can relay perception.
I suspect the quaintness of Flatland renders the parable juvenile, for those who come to this line of inquiry after Fermi, Einstein, Heisenberg, Bohrs, Godel and Feynman. Nonetheless, the case that we cannot conceive of existence, beyond that of our electromagnetic chauvinism, is telling.
Godel was convinced that God must exist, and that mathe
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We don't need a mechanism, per se - not on a macro level, that leads to deterministic outcomes. We simply need a process...
Viewing evolution as having a mechanism is imposing a narrative view on the occurrence, after the fact - much like reaching 60, and looking back at the "story" of your life. It is our insistence in structuring our perception around narrative - this leads to foolish notions. Such as the "idea" which assumes thought emerges from the correct arrangement of fats and proteins.
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This is why I don't have friends - I'm not human.
What are you doing out?!? Get back in your cage!
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Except they specifically say you have more in common than with a randomly selected stranger, so you're "obvious" point is completely contravened by the article.
Wow, that is obvious, if you don't think about it. (Score:3)
All humans have "similar" DNA
Wow, what an amazingly useless statement. Hey, scientists! SlithyMagister has declared that there is no point in describing genomics at a more fine-grained level than the species level. Field's closed -- everyone out!
Of course, the issue is the matter of degree of similarity. They found that friends were more similar than strangers, to the point that they were as similar as fourth cousins. That would be fascinating on its own, but they also found that friends were specifically more similar in two ways
Re:Say it with me... (Score:4, Funny)
... white people are racist
how dare you say white people are racist!
Indeed! This is quite possibly, without exaggeration, the single most cruel and inhumane thing you can do to another person. Accusing another person of racism is so low that, I daresay, it ought to be considered a hate crime! I know I certainly won't stand for being accused of racism. I am a white human being with dignity, and I deserve better than that!
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That awesome Booo-Tay? All the sisters got back!
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And there many "white" Americans who've got some African ancestry and don't even know it.