


Venter Institute Claims Patent on Synthetic Life 163
jimsnail writes "J. Craig Venter and the Institute that bears his name are again moving into new territory in the field of genetics. Genetic patents, that is. They are seeking a broad patent that would give them ownership of a 'free living organism that can grow and replicate' constructed entirely from synthetic DNA. The ETC Group is challenging the claim. 'Scientists at the institute designed the bacterium to have a "minimal genome"--the smallest set of genes any organism can live on. The project, which began in the early 2000s, was partly a philosophical exercise: to help define life itself better by identifying its bare-bones requirements. But it was also fraught with commercial possibilities: if one could reliably recreate a standardized, minimal life form, other useful genes could be added in as needed for various purposes.'"
That's okay (Score:3, Insightful)
Re:That's okay (Score:4, Funny)
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now THAT'S scary..
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Idea ownership (you have heard all this before) (Score:1, Insightful)
I am very familiar with the economic arguments about needing to secure a return on investment, and they are bunk. The most glaring part of it is the fallacy of excluded
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MUHAHAHAHAHA! MUHAHAHAHA!
Evil genius is me!
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Gerbluh? (Score:5, Insightful)
Re:Gerbluh? (Score:5, Insightful)
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like, "We OWNz teH tUbes!!!!1!" or something.
At the very least this fails obviousness test until they have methodology. Like they were the first people ever to have the idea to make a synthetic organism that reproduces and propagates itself through a genetic code. Given that's how natural life works, seems like a bit of a no brainer.
I hope the patent is rejected with a "DUrrrrrr" stamp o
Not patenting all life... (Score:5, Insightful)
From the article: "The researchers filed their patent claim on the artificial organism and on its genome."
These guys have created a brand new form of life from the ground up and are patenting their particular genome. It's hard work, and certainly not obvious or trivial. Given that other biological systems are patentable (e.g., the Harvard mouse, new strains of wheat), this certainly seems to clear the bar for patentability.
Re:Not patenting all life... (Score:5, Insightful)
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No it does not. It reads as follows:
Claim 1. A set of protein-coding genes that provides the information required for growth and replication of a free-living organism under axenic conditions in a rich bacterial culture medium, wherein the set lacks at least 40 of the 101 protein-coding genes listed in Table 2, or functional equivalents thereof, wherein at least one of the genes in Table 4
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If I read between the lines correctly, they have a rough idea of the functions of 482 genes of a bacteria. They think that 101 of them are non-essential for survial and 381 are for protein encoding (how many genes aren't?).
They want to patent the guess and ask any people who create new strains of bacteria base on that tiny bit of knowledge to pay up?!
Can you do that?
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Say someone else understands life better than Venter and comes up with a more mininal gene - is this patent going to cover that? What if the discoverer (hard to call cutting back on nature an invention) of the more minimal gene then wants to use it as a base for experimentation and add other stuff back in - they may well find themselves infringing this patent. What this patent does is cut out a huge swathe of the genetic landscape and say "that's mine" - you can't experiment t
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Well, patent attorney i may not be, but RTFA i did, so you can take your arrogant "knowing the mere basics" bullshit and shove it.
TFA did mention very specifically that this patent application was for the minimum genes necessary for life. Now while in the specific instance, they are merely trying to patent the genome of this single microbe. But given their stated intentions to use that then as the building block for engineering other single-celled organisms by simply dropping in the necessary genes, thi
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I prosecute and litigate patents for a living. Your bluster concerning my ability to "muddle through a patent application" does not cure your error. Neither does your reliance on "TFA," which is egregious
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I heartily encourage you to continue correcting misinformation. I am not suggesting that you keep any information to yourself. I'm not embarrassed at all. I am perfectly comfortable being corrected when I'
The patent madness (Score:3, Interesting)
It's interesting, really. Both the US and the EU patent offices are more than happy to give out patents that are *way* overbroad.
Presumably, this is a part of the transition to an "IP economy", and they've been instructed to keep lower standards as to make sure most of the IP cake has been divided before the international competition becomes too rough.
And then they use heavy-handed tactics to force other countries to submit, misusing the Berne convention [wikipedia.org] and the WTO
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The future. In a world where nobody is free to innovate, develop, invent, produce, or brainstorm, there is only one inevitable result: stagnation.
Patent for Air (Score:2)
2 cents,
QueenB.
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Is that what they're patenting? (Score:2)
If they are patenting the "organism from scratch" concept, then the problem doesn't seem to be ethical,
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Yep and for most of those 20 years development in that field stagnated until the patent was expropriated by the Army during the First World War. Public Key Cryptography deployment also stagnated during the 17 years it was covered by patent.
Now, it's arguable that PKI might not have been developed if it were not for patents, but there were plenty of people who would have been willing to push forward th
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The patent application [uspto.gov] looks pretty specific to me, actually.
this is sick (Score:3, Funny)
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Great (Score:2)
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You're welcome!
Yeah. (Score:2)
Patents on Living Things are Absurd. (Score:2)
now hold them responsible for anything that happens from any synthetic life. Lets see how fast the back peddle.
They are already responsible for that. Everyone is responsible for the consequences of their actions.
There are fundamental problems patenting life. Life replicates itself, life is not an invention and human life should never be owned.
Patents work by keeping people from making the patented article. Applying a patent to an article which reproduces itself is silly. Anyone who owns such an ob
ID theory to the rescue (Score:5, Funny)
Did I just discover a scientifically *useful* application of ID wack-theory? If so, is the universe going to implode, or am I about to be flamed to fiery hell by people who never evolved a sarcasmeter?
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Either you get the politicos to agree and patents like this are made void, or you get them to admit ID is crap. Either way, nerds win!
Oh wait, we've made the common flawed assumption: People reason logically.
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</sarcasm>
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personal genome patents? (Score:2)
Perhaps everyone should patent their own genomes. (Would the lack of having the actual sequence be a problem for the patent office? Hard to believe.) Then everyone could sue everyone else for infringing.
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You'll have to give those dna spectrum pictures to those dirty girls you visit. They'll be like WTF is this?
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or, after discovering your date is a transvestite
"Whoa there now, I don't support your platform... I'm no cross-compiler"
Stuff like that, not to mention all the 'optimized for speed' jokes that could be made.
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Sorry, you were patented.... (Score:4, Funny)
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source
http://oldfraser.lexi.net/media/media_releases/20
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I'm afraid you're way behind the times! I did mention some delayed consequences of US borrowing, right? Check out this graph [yahoo.com]: the Canadian dollar is now within spitting distance of the mighty USD - from a 60% difference to a 6% difference in just over 4 years!
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Good! I'll keep my Canadian change for a while. It might be worth something yet!
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Now all the Candian pennies I've collected over the years will be worth something!!!!!
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In related news... (Score:2)
Drunk man's interpretation (Score:2)
Silly (Score:1)
If anyone at the patent office lets this pass he/she should get whacked with the giant hammer of reason. You can't go around getting patents for entire fields of science.
USPTO application text (Score:5, Informative)
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Tax money was spent on this project (Score:2)
For that reason alone, it should not be patentable.
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If this is really the minimal set (which seems kind of unlikely), I would even call it a huge accomplishment.
Anyway this patent seems to be exactly what a patent was meant to do. It describes a complex invention, and it describes it in a very detailed way. I don't see anything wrong with it. This is the biological versi
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Do you seriously [frontlinedefenders.org] believe [iran-press-service.com] that ?
Try to live in the real world. I do think that indeed, you live in a dream world, under dictators, however, bush is not your dictator.
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Those are indeed anagrams for "United States of America".
I find them funny. I see that you don't.
Maybe you should lighten up a bit.
And work on your punctuation, that last sentence is an abomination.
As for the anagrams themselves:
Neofascism attitudes are ripe in the US [google.com]
Consider this list [secularhumanism.org]:
1. Powerful and continuing expressions of nationalism.
2. Disdain for the importance of human rights.
3. Identification of enemies/scapegoats as a unifying cause.
4. The supremacy of t
heh (Score:4, Funny)
Hmm... (Score:1, Funny)
I've been there a few times, and there are quite a few living on the minimum requirements for gene usage.
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Mixed Reaction (Score:3, Interesting)
My reaction to this is mixed. First, I'm suspicious of this kind of sweeping patent protection in general. And it is far from clear (in the cited article at least) that they actually have such a genome yet, so patent protection seems strange. "We think we are going to do this, so grant us a patent."
On the other hand it may take 20 years or so to actually be able to use this kind of technology in meaningful ways (and have drugs produced this way approved by the government). So granting patent protection now means that it would expire just about the time that people might be able to take advantage of it.
On the other other hand, if they really are patenting the idea, they'll probably re-patent (or extend the patent with new claims or however that works) any usable variation when they actually get it so they're likely to find ways to stretch such patent protection out for quite a while.
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It's not just an issue of drugs. It's also for the manufacturing opportunities that this offers. One example would be a organism that cheaply creates ethanol or hydrogen from biomass.
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The question is, have they actually made this bacteria, and does it actually live, reproduce and die like a bacteria should? At this point it's not clear they invented anything, more than just taking a bacteria, re
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But thanks for correcting me.
Just a quick flash idea... (Score:2)
(badgers, badgers, badgers becomes) patents, patents, patents
(mushroom, mushroom becomes) lawsuit, lawsuit
(snake part goes) Out-of Court settlement! Settlement
Etc.
Thanks. I have no skills.
Cheers,
Mike...
The future is not bright... (Score:3, Interesting)
British already did it... (Score:2)
Title is wrong, or at best misleading. (Score:5, Informative)
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It's happened before if I remember correctly (see Monsanto GM s
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You're talking about programs, aren't you!
I'd offer myself as prior art.. (Score:3, Funny)
Too late, prior art (Score:2)
Seems as though a patent for artificial life, belonging to one Victor Frankenstein, has already expired. Along with a sub-category submitted by Abby Normal, signed off by The Man with Two Brains.
Take it to the courts! (Score:2)
"Dibs" on a new steady revenue stream (Score:2)
There's no prior art yet, and it's inevitable.
I claim prior art and have one example to submit (Score:2)
I used the GATC encoding scheme.
All your offspring are belong to me.
I just trumped all y'alls (Score:2)
It's not about patenting life (Score:2, Informative)
Patents are now 20 years (Score:2)
Don't be afraid. Be very very afraid (Score:2, Insightful)
Lifeforms reproduce themselves, patterning surrounding matter and
energy into more of their own form.
Over several billions of years, natural ecosystems have evolved
checks and balances on overabundance of any particular lifeform.
Other lifeforms co-evolved and the lifeforms limit each other
(by eating each other, by competing for the same resources, etc.)
The ecosystems change, but rather gradually, as many stalemates
(equilibria) in the energy and strategy balance of the
competitive pattern
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Particularly one that would work in all environments. The worst case scenario is making a certain specific bio-culture wierd. (i.e. a creature might be able to rule the -10 to 80 degree life zone, but could not stand temperatures under -30, or over 90, so we just move to canada/florida and kill it during the winter/summer.
Prior Art (Score:2)
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Tyrell Corporation? (Score:2)
Bible = Prior Art (Score:2)
Patent official (I hope they are at least this intelligent): What type of life do you wish to patent.
Fool: NO. I want to patent ALL life.
Patent Official: Why, there might be prior art.
Fool: NO, everyone else made "natural life", I am going to patent life that anyone makes, i.e. SYTNETHETIC life.
Patent Official: Have you heard of God? He is this big, super-powerfull creature that some people think may have created life. That means that all life is synthetic, an
misleading title, marginal patent (Score:4, Informative)
As mentioned previously they're not patenting synthetic life but a specific minimal set of genes required to produce a replicating bacterium. There was a non-trivial amount of work that went into researching these genes and determining the least combinations necessary for replication in a solution that provides all the basic building blocks (ie. this bacteria will not be synthesizing its own amino acids, I would imagine).
This is could be important for industrial biosynthetic applications. Every protein expressed by a bacteria increases its metabolic load and decreases the efficiency with which it can convert input (sugars, amino acids, nucleotides) into the desired output (insulin, drugs, other useful biocompounds). By determining the minimum necessary set of genes for replication a ground-state bacteria has been designed that can be used as the starting point for designing more efficient expression systems.
It also allows these expression systems to be more fully characterized which can help when attempting to determine and modulate the effect metabolic load and evolution will have on a vat of bacteria as it progresses from generation to generation. One problem with these systems is that synthesizing extra compounds increases the metabolic and decreases the replication rate. If it is possible for the bacteria to mutate and stop expression of the product their metabolic load decreases and they begin to replicate faster; this causes vats of bacteria to tend to evolve such that they stop producing the useful compound. There are ways to get around this (such as turning production on and off using external chemical signals, tying production to survival, etc.) that might be optimized in such a minimal system. Engineering life is tricky because of the extremely high number of potential interactions to be analyzed for every new configuration; it is more difficult because many of these interactions can't be calculated or simulated.
This patent won't be all that useful for more complex human proteins as these require an array of post-translational modification proteins that change the product after the initial synthesis; thus they require a correspondingly complex expression system derived from a yeast cell or an animal cell (I think some worms have been used to develop complex expression systems); Alternately bacteria can be modified to produce the modification proteins. These expression systems have doubtless already been patented or are no longer patentable, so this new patent probably won't be very useful until it is bundled with a set of associated patents for efficient expression systems for various compounds.
What defines synthetic "life"... (Score:2)
Why not just refer to them as "autonomous bio-chemical machines" and simply avoid the philosophical overhead that is sure to come from claiming you are frankensteining artificial creatures in some dark laboratory located in our back yard?
I'd question if "Life" is soon going to be someone's registered trademark, but apparently Mikey already squatted it a few decades ago...
Minimal life forms in 1997? (Score:2)
Reference:
Eigen and Oehlenschlager, 30 years later - a new approach to Sol Spiegelman's and Leslie Orgel's in vitro evolutionary studies: dedicated to Leslie Orgel on the occasion of his 70th birthday, M. Eigen and F. Oehlensc
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2) Artificial genomes have been made before, both bacterial artificial chromosomes (BACs) and yeast artificial chromosomes (YACs). This is by people who've actually made these things, not just thought it would be a neat idea.
3) Patenting vague obvious ideas (and this idea is obvious if you have any background in the field) is exactly what Verizon is trying to do by claiming to have patented the concept of voip on a phone. It's also what the
question here! (Score:2)
Hmmm. I wonder... (Score:2)
*ponders*
synthetic dna is not synthetic life (Score:2)
A few throwbacks claim that life can only come from life, i.e. there is some inherent patterns in the cells you just cant recreate from inert chemicals. Other claim some life energy or essence, but I think thats a supersition.
The previous attempt at synthetic life was some viruses
Better than lots of Slashdot Readers (Score:2)