DNA-rainbow, A New Vision of Human Chromosomes 161
An anonymous reader writes "Two scientists have rendered amazing pictures using datafiles from the human genome project. They assigned different colors to the DNA and rendered images showing interesting patterns and strange structures of our chromosomes. It might be a groundbreaking new idea for displaying and maybe better understanding our genes. With its fascinating pictures it is a beautiful mix of science and art."
Magic Eye? (Score:5, Funny)
Re:Magic Eye? (Score:5, Informative)
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Kevin: "Kevin Smith? Kevin smith kevin smith!"
Mr. Smith: "Kevin kevin smith smith, kevin smith kevin smith."
Kevin: "Smith, kevin. Smith kevin smith smith kevin kevin smith."
Huh - I see Skeletor (from He-Man) (Score:2)
Lame (Score:4, Informative)
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We took the genetic code from huge data files and assigned a color to every of the four bases. Then we rendered these fascinating pictures, showing the genetic code of humans in color. You can see crazy structures and strange patterns in the images, best viewed when shutting your eyes just a little bit. Click on a link to a chromosome above and use your imagination to get a new view of your genes.
Sounds like junk science to me.
Re:Lame (Score:5, Insightful)
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Searching DNA is *hard* (Score:2)
DNA is very very very difficult to search and index effectively, especially since scientists are very interested in finding sections that don't quite match.
A good friend of mine (hi Paul [google.com]) has been working on hardware and / or software searching algorithms for a couple of years now. I used to live over his back fence, and he's talked me through a couple of his ideas.
<surprise> Oh, I see he filed a patent. </surprise> Well I can't say any of that was obvious.
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I used to live over his back fence, and he's talked me through a couple of his ideas.
Hey Tim! Love your show man. Especially that guy Al. [go.com]Re: (Score:2)
The input is random, so we are seeing patterns. A chromosome is linear. These guys wrapped that single long line into a box. Where they put the line breaks is completely arbitrary. Any patterns that you see must be formed by interesting "stacking" of lines together, and that effect is arbitrary. Pretty pictures, but utterly meaningless.
Kinda simple, too. Besides downloading the 40GB or so of genomic data from NCBI, all they needed were l
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I would love to get something like this done for my wife. Of course I would need to remove my tinfoil hat and not think about how they could just be gathering dna samples for the genetic superarmy.
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It was really pricey, so its the only piece of art we've bought for our house, but it looks cool and is unique so I think it was worth it.
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There are 4 bases, yes, but they can only form in specific pairs. Adenine can only pair with Thymine, and Cytosine can only pair with Guanine. So there's really only two values. In other words, the two possible base pairs can be represented as the two possible values of a binary digit - a bit. Instead of using 4 colors to represent the DNA, only two are actually needed, assuming you use one base-pair per pixel. But really, looking at a 100 million bit long bi
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Unfortunately Slashdot will not render:
A pattern is a patterns is a pattern (Score:5, Insightful)
Any pattern can be modeled in an algorithm, and from this algorithm it can be extrapolated. A set of data without any patterns is noise; random data. An algorithm found in a dataset speaks of a function, and understanding functions in the human genome leads to better understanding of what we truly are.
Re:A pattern is a patterns is a pattern (Score:5, Insightful)
Sol Robeson: Just that a pattern exists does not give meaning to the pattern. The Golden Rectangle [wikipedia.org] was applied to the human body by Da Vinci and others, but no great significance can be discerned except that vertebrates tend to be symmetrical. The heavens did not burst forth as our creator revealed himself. The DNA pattern is more of the same - searching for patterns tends to yield them eventually.
Re:A pattern is a patterns is a pattern (Score:4, Interesting)
The [ebay.com] problem [ebay.com] is [farshores.org], how [metro.co.uk] does [wkyc.com] one [jsonline.com] determine [goldenpalaceevents.com] which [pittsburghlive.com] patterns [local6.com] indicate [nbc5.com] something [nbc5.com] and [nbc5.com] which [nbc5.com] patterns [nbc5.com] are [nbc5.com] just [nbc5.com] convincing [wtol.com] illusions [reuters.com]?
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"As soon as you discard scientific rigor, you're no longer a mathematician, you're a numerologist."
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The Golden Rectangle was applied to the human body by Da Vinci and others, but no great significance can be discerned except that vertebrates tend to be symmetrical.
I'm not sure why parent post did not cite the Golden Ratio [wikipedia.org] instead, since that is what Da Vinci was mostly working with. BTW, the original expression was more along the lines of "the smaller part is to the larger part as the larger part is to the whole", which implies a much broader application than the algebraic presentation in the Wikipedia article. Also, note the use of G.R. in grecian architecture and sculpture predates Leonardo by about 1500 years.
There is certainly significance in the G.R. in that
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An algorithm found in a dataset speaks of imperfect compression.
As to "what we TRULY are", we are everything that we are, neither more nor less, in all our messy complexity. Reductionism generates epistemological convenience, not metaphysical revelation. Although Platonists in reductionist clothing have been overstating their case for centuries.
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Re:Lame (Score:5, Insightful)
The Bible Code people claimed that their ability to find patterns in a particular text of a particular religion both validated the truth of that religion and also allowed predictive ability on world events.
These guys are saying, "Hey look, if you display a bitmap representation of genomes, they look pretty."
I am sure that you can see the difference between these two claims.
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Using the Bible Code method, you can find a 'prediction' of the death of Princess Diana in the book 'Moby Dick'
Also, Genesis contains the phrase "Darwin got it right"
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Ever seen a few "maps" of the Internet [opte.org]? Completely pointless, but it helps people to visualise the scope of the whole thing, even though they can't do anything useful with it. It's mainly art, but it also shows us something we can't understand in a way that is more hu
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Um. Or did you mean something else ?
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Ok, so they could just hav
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Wake me up when they find the differential equations governing DNA.
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Visualizing this data allows us to use our eyes to search for patterns. Which is actually a great idea, considering how good our ey
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Sure, I agree that any time someone purpose to find a special pattern
I dunno... (Score:1, Funny)
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Your chromosomes... (Score:5, Funny)
Would you like to optimize your chromosomes?
[Yes] [No] [Cancel]
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Hey, baby. . .. (Score:5, Funny)
I see no patterns! (Score:2)
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Oops (Score:5, Funny)
Hopefully the next version will have developed a natural defense mechanism to handle the strain Slashdot puts on servers.
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Does anyone else see a pattern forming here?
Arrgh! (Score:3, Funny)
I need tissues!
Good Science/Art websites? (Score:2, Interesting)
Re:Good Science/Art websites? (Score:5, Informative)
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The Really Paranoid Reader might wish to investigate which piece of music created this [draves.org] one.
On a related note (all pun intended), it would be interesting to synthesize the chromosome images to sound. :)
Perhaps fragments of interesting music might be lurking there. Something to listen to while jaywalking with your iPod anyway. It would add that extra dimension to a Darwin award
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forget RIAA (Score:1)
Mirror here ... (Score:1)
Not very spectacular, IMHO.
CC.
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Why 2D? (Score:1)
I used to think of the DNA as a kind of a programming language for the physical laws that exist in the universe. DNA in its very basic function is a mechanism to assemble complex organic molecules from simpler molecules and / or atoms, so I'm not sure wether we can extract any information from it using a
Hey, it looks like piet source code! (Score:2, Interesting)
http://en.wikipedia.org/wiki/Piet_(programming_lan guage) [wikipedia.org]
http://www.dangermouse.net/esoteric/piet.html [dangermouse.net]
It'd be nice to be able to load the chromasomes up into the piet interpreter, and see what comes out!
Wouldn't it be interesting, though, if it turns out that the genome could be understood as a 'program', and a specially coded interpreter could process it...
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The genome is a program and children are it's binaries. But please do tell me more about that interpreter stuff, that seems, uhm, nice.
Seen it Before (Score:2)
Near miss (Score:1)
I've seen that pattern before (Score:3, Insightful)
Paradoelia (Score:2)
Strange structures (close your eyes just a little bit to see more details)
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That was not the point (Score:2)
Genetics (Score:4, Funny)
Why 2D? What happens in 3D? (Score:2)
As we statisticians say (Score:1)
There is, of course, much ongoing research in finding mathematical patterns in DNA. I had a paper published about how DNA SNPs seem to follow a Poisson process in their distribution. Does someone know a good way to visualize Poisson processes? When graphed as they do, it just looks like a sequence of randomly spaced dots.
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Isn't that pretty much what we would expect as the null hypothesis? It seems like the deviation from poisson would be the interesting phenomenon in this case....
More specifically: if point replication errors occur randomly and without mechanistic bias (i.e. they're unrelated to chromatin structure, or some other higher-order biological process), it seems like a poisson model would be the simplest descriptio
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Copied verbatim from the methods section. Page 629, left column, mid-page.
Sentence begins: "Given that the number of SNPs...."
That sounds quite contradictory. If SNPs aren't distributed according to a Poisson process, then the scan statistic found those deviations. The model appeared to work quite well, as the diagnostics indicate.
OK, I'm becoming convinced that you don't understand the paper:
The "scan statistic" is a measureme
Hmmmm... (Score:2, Funny)
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No, I just think you've unloaded a bunch of big words (some not used correctly, by the way) and linked to a video of a dry low-level lecture with graphics that are no more sophisticated than these guy's in order to appear cool.
"Overall, I think this is wicked cool, but amateurish from the standpoint of science. Actually, I'd like to see a Gerald Edelelman approach to handling and analyzing the DNA -- which would be wicked cool!"
Wicked cool -- the
This isn't a new idea (Score:2)
Binary data (Score:1)
[Happosai]
windows is more artistic than our dna (Score:2)
(and it's also more artistic than linux)
Just out of curiosity... (Score:1)
http://en.wikipedia.org/wiki/Alternate_reality_ga
mov ax,13h; int 10h (Score:1)
And Thus... (Score:2)
This is teh crap (Score:2)
This publicity-stu^H^H^H^H^H^H^H^H^H^H^H^H^Hexperiment is teh crap because:
Heroes (Score:3, Funny)
This is silly/arbitrary (Score:2)
Sheesh. How about 3 dimensional spiral rendering or spherical or (for the "flat worlders") a cube? Granted, even with
This is art? (Score:2)
Is there really information there? (Score:2)
They're all Rainbow??? (Score:2)
Slashdotted (Score:2)
You can get 'deeper' pages at http://www.dna-rainbow.org/chromosomes/X.html [dna-rainbow.org] where X is the chromosome number (1-22) or x or y (lowercase).
Completely pointless (Score:3, Interesting)
I can understand if they took two different genomes from the same species and did some kind of comparison: different colors for matches, indels, translocations, silent/synonymous/non-synonymous SNPs, etc. Or translated the sequence and colored by hydrophobicity/charge/polarity/whatever. Or showed haplotype conservation between species.
At least that would tell you something, this is just a bunch of pixels with no meaning. A vaguely similar thing I've done was to plot plot SNP density (as color intensity) over the genome - but that was for a specific project, I didn't realize such things are "new visions".
There are definitely prettier visualizations out there too: http://acg.media.mit.edu/people/fry/genomevalence [mit.edu]
Even this [visualcomplexity.com] is a lot more informative (I think www.visualcomplexity.com was mentioned on slashdot a couple of years ago).
shift numeric (Score:2)
Then, this would will be irrefutable proof of something, some sort of README.first, or just random gibberish for monkeys to type out.
Contact.
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redundant mod is lame (Score:2)
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We share a large (not 99%) of our DNA with shrimp (and shimp, whatever those are) because most of it is involved with cellular functioning, you idiot.
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Cut the guy some slack, he's not that far off (Score:2)
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