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Biotech Science

Scientists Create New Human Embryonic Stem Cell 713

Homework Help writes "U.S. scientists were successful in creating a new human embryonic stem cell. From source, "U.S. researchers said on Monday they have created a new human embryonic stem cell by fusing an embryonic stem cell to an ordinary skin cell. They hope their method could someday provide a way to create tailor-made medical treatments without having to start from scratch using cloning technology. That would mean generating the valuable cells without using a human egg, and without creating a human embryo, which some people, including President George W. Bush, find objectionable. ""
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Scientists Create New Human Embryonic Stem Cell

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  • by daveschroeder ( 516195 ) * on Monday August 22, 2005 @12:05PM (#13372739)
    That would mean generating the valuable cells without using a human egg, and without creating a human embryo, which some people, including President George W. Bush, find objectionable.

    should read:

    That would mean generating the valuable cells without using a human egg, and without destroying a human embryo, which some people, including President George W. Bush, find objectionable.

    To echo something I said the other day: personally, speaking as someone whose training has been almost exclusively in medical science, I fully support embryonic stem cell research. We have embryos that are and will continue to be destroyed today, that could absolutely be harvested for research. However, to ignore any ethical debate on such issues is just as ignorant as some would paint the opposition. Scientifically, an embryo is, strictly speaking "human life"; so, when and why is it ok to end such life, regardless of the state it may be in? Why should we not examine the important ethical questions? There is absolutely no doubt that significant scientific benefit could come from cloning or farming of humans in more developed forms. So should we push forward with things such as that, full force? Or should we take pause ask important questions that define our very humanity?

    Remember - and admittedly, this was due in part to the timing of discoveries, but is true nonetheless - President Bush is the first president to allow federal funding of any kind to human embryonic stem cell research. Further, there were no "bans" on embryonic stem cell research: there was a restriction on federal funding of research that didn't use approved, preexisting lines. Without regard to the purported scientific use{ful,less}ness of the existing lines, the fact remained that funding was indeed provided, human embryonic stem cell research (including the destruction of embryos) was not banned, and a conservative approach was taken. Further, large research entities - such as the state of California and the University of Wisconsin System - have had little difficulty in establishing research centers to skirt federal funding restrictions and still commit federal-scale research funds to embryonic stem cell research.

    The ethical considerations are important: should we also clone humans? After all, aren't you "anti-science" if you oppose unrestricted human cloning?

    Just because something is nothing more than an amalgam of cells - or a single cell - doesn't mean it doesn't represent, even if only philosophically, human life. Why is it valid in the macro scale, but not micro? Note I'm not saying that even embryonic stem cell research that involves the destruction of embryos - indeed, embryos that would have been discarded anyway - shouldn't be done; I am saying that there should be ethical debate and discussion: as I'm sure many would agree, just because you can do something doesn't necessarily mean you should.

    In any event, I applaud researchers for finding a potential method that may allow embryonic stem cells to be used without the associated destruction of human embryos, thereby removing a significant and valid ethical consideration as a barrier to the further exploration and use of these cells as potentially valuable tools.

    Note: I didn't vote for Bush, and don't personally support Bush's current human embryonic stem cell policy.
    • A restriction on federal funding *is* a restriction of research, though. It's like trying to travel without having a valid driver's license or some other form of photo ID - you can do it, but there's gonna be a lot of hassles (try flying or booking a hotel room without photo ID!).

      That's not to say that every possible study under the sun should be funded, no matter what it's about. But the discrimination between what is and what isn't funded should be based on objective criteria, not on one man's personal re
      • by daveschroeder ( 516195 ) * on Monday August 22, 2005 @12:18PM (#13372838)
        I didn't directly acknowledge in this particular post that the restriction on federal funding does indeed effectively restrict research, but yes, I'd agree with that.

        But the discrimination between what is and what isn't funded should be based on objective criteria, not on one man's personal religious beliefs.

        Every ethical debate will be colored with the body of our experience. Some will be religious, some will be considered by yourself to be "objective", others will come from different philosophies. That's why it's called debate.
        • by learn fast ( 824724 ) on Monday August 22, 2005 @12:46PM (#13373075)
          Regarding the debate, Bush is losing.

          Most Americans [pollingreport.com] now think the ban should be dropped and the government should "fund research that would use newly created stem cells obtained from human embryos".
          • by twiddlingbits ( 707452 ) on Monday August 22, 2005 @01:05PM (#13373212)
            Most Americans are ignorant about Stem Cells and only hear the Marketing Hype that they promise "cures" for everything from A to Z. Who would NOT be for something that does that?
            • by Skye16 ( 685048 ) on Monday August 22, 2005 @01:40PM (#13373536)
              Most people who are against it are also for in vitro fertilization for couples who otherwise couldn't have children. nevermind that an excessive number of eggs are harvested and fertilized before one is selected and transfered back into the uterus (excessive is a strict definition in this case - I'm not talking hundreds of thousands or something, just more than will be necessary for the procedure). nevermind that these eggs are either kept frozen or destroyed after the woman becomes successfully impregnated.

              really, pick one stance and stick with it. either embryos are alive and need to be protected, or they aren't and don't. I don't see how destroying embryos on the way to having a child is somehow more ethically acceptable than curing "everything from A to Z".

              Personally, I have no problem harvesting embryos, even if a woman consents to being a "farm" for eggs. An embryo is no more a human than cake batter still in the mixing bowl is a cake. Obviously, this is where my opinion diverges from many of you. That's okay. All I ask is consistency in our respective positions.
          • by mikehoskins ( 177074 ) on Monday August 22, 2005 @04:26PM (#13374724)
            Regarding the debate, Bush is losing.

            Most Americans now think the ban should be dropped and the government should "fund research that would use newly created stem cells obtained from human embryos".


            Most Americans thought slavery was a good thing and that "people of color" should not have the same rights as those who were not "people of color."

            So, I'm afraid I have no clue what point you were trying to make.... Does 50.00000001% or 99.999999999% make it *right*?

            Of course not.

            I wonder how barbaric we will look 50, 100, or 150 years from now.
      • If embryonic stem cell research is the panecea everyone claims it to be, why aren't more companies coming out of the woodwork to fund it. The patent rights to a cure for all the deceases this can supposedly cure would be a license to print money.
        Also, it's not just one man's religious beliefs, it's the moral and ethical beliefs of millions of Americans. For some of us, religion has nothing to do with it.
        • I'd figure on there being 2 main reasons.
          1)There's no proof it will work yet. Many great things didn't getting the funding they deserved because there was no guarantee it would work.
          2)And what exactly would they patent? You'd have a hard time patenting stem cells since nature invented them long before the Pharm companies did.
          I suppose they could patent the method of using them, but a rival company could easily take what they came up with, modify it enough so they can get their own patent and save a lot
        • by Prospero's Grue ( 876407 ) on Monday August 22, 2005 @12:36PM (#13372981)
          If embryonic stem cell research is the panecea everyone claims it to be, why aren't more companies coming out of the woodwork to fund it. The patent rights to a cure for all the deceases this can supposedly cure would be a license to print money.

          No form of R&D is a licence to print money - especially at such an early stage. There is much work to do, many lines of investigation to be explored, and a lot of paths will lead to dead-ends.

          The return, if it comes at all, will be long in wait - and a lot of commercial enterprises would simply not survive long enough to reap their dividends.

          The potential in this, and many new scientific fields is enormous; but to try and fit that into some economic model is the kind of thing that the "square peg in a round hole" simile was invented for.

          Also, it's not just one man's religious beliefs, it's the moral and ethical beliefs of millions of Americans. For some of us, religion has nothing to do with it.

          Very true, and while I am a supporter of stem cell research, believe an embryo is a life, and would prefer that embryos destined to be discarded be used rather than wasted; I understand the other side.

          This research is controversial, and runs counter to the core beliefs of more people than just religious zealots. The government has elected not to fund it with public money, but has allowed the research to continue on its own merits. I think that's the most balanced approach one could hope to take.

        • by brunson ( 91995 ) *
          If you find it morally or ethically objectionable to destroy human embryos then you'd better get down to your local fertility clinic and start protesting. They routinely fertilize 50-70 eggs for implantation and when one (or four or eight) finally takes, the remaining dozens are destined either for stem cell research or the incinerator.

          At least in research they're giving their 'lives' to the possible benefit of may sick individuals. Otherwise, in the vocabulary of the Anti-Choicers, they're just abortions
          • by lgw ( 121541 ) on Monday August 22, 2005 @01:11PM (#13373267) Journal
            you find it morally or ethically objectionable to destroy human embryos then you'd better get down to your local fertility clinic and start protesting.

            Don't say that too loudly, you'll start something. There are people who feel this way. You may try to dismiss them as religious nutjobs, but in a representative government, even the nutjobs' opinions count. You can't say "there's no debate on this issue, because those who disagree with me are idiots".

            This is a very cool technology, because it *deos* let us ignore the debate on harvesting embryos and move on to doing useful research!
            • Stem-cell cures are probably two decades away, if proven viable.

              No side of the stem-cell debate is AT all honest.

              On the left...
              The pro-embryonic research crew is 1, telling sick people that George Bush is killing them, when in fact they have a death sentence and stem cell research may cure FUTURE patents, but not likely the current ones.

              This is more about politics than anything else. A prohibition on federal funds isn't a prohibition on research. Bush was the first President to approve ANY funding, and al
              • The pro-embryonic research crew is 1, telling sick people that George Bush is killing them, when in fact they have a death sentence and stem cell research may cure FUTURE patents, but not likely the current ones.

                Not quite - current researchers say they're about 3-5 years away from starting human trials in repairing spinal cord injuries with stem cells. More here [fsma.org], though due to the halt on federal funding, this has been somewhat derailed (we were 5 years away in 2000).

                • We're always 5-10 years away from true breaktrhoughs, which 5-10 years from now are still 5-10 years away.

                  See: Flying Car

                  I think the previous statement about 20 years is a fairly balanced guess, but we'll see about that 20 years from now. ;-)
              • by dougmc ( 70836 ) <dougmc+slashdot@frenzied.us> on Monday August 22, 2005 @01:49PM (#13373603) Homepage
                Of course, your summary isn't really honest either --
                The pro-choice crowd was EXTREMELY excited about the ability to destroy more embryos as part of their "proof" that embryos aren't life.
                You're painting the pro-choice crowd with an awfully broad brush here. A large number of `pro-choice' people (including myself) don't really like the idea of killing embryos for whatever reason, but are pro-choice because we think it should be up to the mother (and father, though probably to a smaller extent), not the church or the government.

                I suspect that there may have been a few pro-choice people who are as you said they are, but I suspect it's a small minority.

                if you listen to the argument on the left that there is NO MORAL question
                The `left' says there is no moral question? It may be that the `right' is generally `pro-life' and the `left' is generally `pro-choice', but these are hardly hard and fast rules. And I'm not aware of many `pro-choice' people who would claim that there is `NO MORAL question' about abortion (and stem cell research) at all.
              • If this discovery is confirmed then it means that Bush's compromise worked out wonderfully, whether you like him or not. He allowed the basic research to continue, and scientists found a solution.

                I can ignore your insulting but expected demonization of the "left", but this bit is just absurd. It's "comfirmed" that Bush is a genius? No, it's evidence that scientists are willing to make heroic efforts on behalf of all of us desipte the inane restrictions Bush put in place. There's no rational argument that th

        • by dgatwood ( 11270 ) on Monday August 22, 2005 @12:49PM (#13373099) Homepage Journal
          The moral and ethical beliefs of millions of Americans include the mistaken belief that all Catholics keep guns in their basements and that everyone else but their chosen protestant denomination is going to Hell, too.

          IMHO, embryonic stem cell research is even less ethically sticky than organ transplant. If your infant is on life supoport with no hope of surviving, at what point do you pull the plug? Do you agree to give those organs so that some other infant might live?

          With stem cell research, you're talking about taking cells from something that hasn't even evolved beyond a tiny ball of cells---far less alive than that infant---and yet most parents would gladly give up that infant's organs so that someone else's child might live, but a surprisingly high number of those same people would not be willing to give up a handful of cells from a frozen embryo so that adults can live.. It's an appalling ethical contradiction.

          The ethical arguments against stem cell research are grounded in the abortion debate. Unfortunately, the [expletive deleted] Republicans have created this politically charged anger over the abortion issue. The dyed-in-the-wool religious right folks don't want to feel like they are changing their stand on destroying a fetus. Unfortunately, they can't see past the rhetoric to realize that this is a completely different fundamental issue.

          The result is a group of people who have become so dogmatically indoctrinated in their position that it would take a miracle to change their minds. Because of them, legitimate medical research that could save lives is being stifled in the name of God. That's just wrong, by any definition, in much the same way that the Church stifling Gallileo was wrong....

          I'm not saying there are no ethical issues. If we see people creating fetuses for the purpose of extracting stem cells, many could legitimately consider that morally and ethically reprehensible---myself included. However, as long as you are extracting tissue from a fetus that is going to die anyway, not taking advantage of those cells would be equally morally and ethically indefensible.

      • The question here is one of morality, not whether the science is valid or not. Surely you would not say that anything is moral in science, so how do you plan on objectively defining morality? The only method that is really practical in a democratic country is to define it based on majority opinion, rightly or wrongly, which is (in theory at least) the same way the legal system is set up. Whether you like it or not, it seems that the majority, or at least their elected representatives, view this particula
        • I agree. I would much rather live in a country which is hesitant to commit to stem cell research because of ethical grounds (with which I personally disagree) than one which allows `medical research' programs which involve torturing thousands of Jews, for example - the other end of the same scale.

          Stem cell research should definitely proceed eventually, but only after clear ethical guidelines have been worked out that will prevent it degenerating into something along the lines of cloning entire humans as

    • by Itchy Rich ( 818896 ) on Monday August 22, 2005 @12:16PM (#13372813)

      Scientifically, an embryo is, strictly speaking "human life"...

      For that to be correct you first have to define "human life" in terms that science can measure.

      If you mean capable of human emotion then I would say you were wrong (others may disagree based on their beliefs) since at early stages the embryo has no complex nervous system.

      If you mean "genetically human" then you're right, but so is some of the gunk under my toenails.

      If you mean "has the potential to become human" then you're right, but the tense is important, i.e. it's not human yet, and we still haven't defined what being human means so can't measure the point at which it becomes "human".

    • by dr_dank ( 472072 ) on Monday August 22, 2005 @12:16PM (#13372815) Homepage Journal
      However, to ignore any ethical debate on such issues is just as ignorant as some would paint the opposition.

      I understand that most of the embryo's are leftover from fertility treatments and would otherwise be discarded. What moral qualms could be had for experimenting on something that would otherwise go in the trash?

      Why aren't the religious zealots freaking out about the "unborn" being unceremoniously dumped into a biohazard waste bin at the fertility clinic the same way they freak out if they experiment on it, possibly saving lives in the process?

      • It's not that simple.

        The moral qualms come from the fact that today, they're discarded as a side effect of trying to help couples start a family; to bring a life into the world that will be cared for and nurtured, and to propagate our species.

        Once there is a need for a supply of such embryos, the creation and subsequent destruction of said embryos might be encouraged, and may outstrip today's supply. As I said, we could certainly also farm humans for immense scientific benefit and usefulness. But does that
        • I'm not sure I can figure out what side of the fence you're on.

          So, it's okay to create a factory for fertilized eggs and destroy the leftovers if it means someone who couldn't have a child naturally can grow one rather than adopt, but it's not okay to create them for the potential benefit of millions of people that are already on earth and suffering from debilitating diseases?
          • by daveschroeder ( 516195 ) * on Monday August 22, 2005 @12:53PM (#13373125)
            I'm not on any side of the fence. I'm simply laying out the arguments.

            We already had a societal debate on whether it was worthwhile for the purposes of fertility. The answer is apparently, "yes, it is."

            We must also have the debate on whether it's okay, on a potentially much larger scale, for medical research. It's not a foregone conclusion, by the way, that embryonic stem cells are necessarily a magical panacea for all disease. The may in fact be very useful. But to paint them as the end-all be-all (not saying you, personally, are doing that) is just as disingenuous as the opposition.

            I already said I, personally, support unrestricted human embryonic stem cell research.

            I also support fertility clinics.

            My positions are perfectly consistent, so don't try to paint me as some kind of fence sitter. What I'm trying to say is that ethical debate is warranted for new uses of human embryos that require their destruction. The fact they're already discarded (i.e., destroyed) for fertility purposes doesn't negate the need for any debate for new uses. Further, as I said, such use may at some point outstrip supply for fertility clinics. Then what do we do?

            I'm not saying I have the universal answers to these questions, just that they're there, and shouldn't be ignored. I know what my own personal opinions are, but that's irrelevant to the topic at hand, which is my assertion that debate on this topic is very valid and warranted.
          • by TomSawyer ( 100674 ) on Monday August 22, 2005 @01:17PM (#13373341) Homepage
            I'm not sure I can figure out what side of the fence you're on.

            This is very telling of why there is such little progress on these issues. Instead of focusing on seeking truth too many people are seeking sides.

        • Once there is a need for a supply of such embryos, the creation and subsequent destruction of said embryos might be encouraged, and may outstrip today's supply.

          And one day water might turn purple, but until then, how about we just make decisions based on the fact that it's blue-ish right now?

          We've got several hundred guys whose job it is to make up new laws. If people start farming abortion clinics, I bet one of them will get on top of it pretty quick. And we'll all support them, because your opposition i
      • People in concentration camps were most certainly going to die. Does that make it alright for Mengle to perform his medical testing on them? Some of his research on the effects of extreme environments is genuinely scientifically useful, but just because the subjects were "on their way out", does that make the experiements alright?
        • since when is a living human the same as a few cells?

          I shed "human cells" every day in the form of hair and skin.. would you call those cells "human" ?

          having a brick doesn't mean you have a house.

          cells are cells, they are not humans.
      • by Alex P Keaton in da ( 882660 ) on Monday August 22, 2005 @12:47PM (#13373080) Homepage
        So it is somewhat analagous to eating chicken eggs? I never understood why vegetarians won't eat eggs. (I understand why Vegans don't) Eggs we eat are the unfertalized ones, so they won't ever become chicks. Even if we don't eat them. (Not to be totally vile, but the same way that the egg that ebds up on a maxi pad each month will never become a human)
        They actually check the chicken eggs before shipping them off to be eaten....
        On the converse- get caught destroying a bald eagle or a piping plover egg, and see how the government feels about the "not yet born."
        I am going to be honest- I have trouble formenting an opinion on stem cells, because each time I lean one way, something pulls me back in the other direction. My question, if stem cells lead to a cure for cancer, will those who opposed the stem cell research boycott the treatment, and die?
        • I never understood why vegetarians won't eat eggs.

          It has something to do with the way the chickens are raised, locked in tiny cages for their whole lives, choking on their own filth, and forced to live as egg factories. They become physically and mentally ill in that environment, demonstrating self-mutilation behavior and a drastically reduced lifespan.

          Many vegetarians will buy "free range" eggs, which cost much more, but are harvested from chickens that are not kept in cages.

          Here is some good docu [cok.net]

      • >Why aren't the religious zealots freaking out about the "unborn" being unceremoniously dumped into a biohazard waste bin

        As a religious zealot, I'd say that most of us ARE very upset (not "freaking out", though) about this. But it is within the law for people to do so, so there's nothing we can currently do about it.

        As for "freaking out" about experiments on embryonic stem cells, that activity in itself isn't one I see a moral barrier against; far from upsetting me, I could wholly support that research

    • you're absolutely right. we need only think "ahead" a few years and imagine what might be possible. if embryonic stem cells, than what about more mature embryoes? how about fetus farming? the potential is enormous. it's a thought i don't like.
      • That's damn right. Plus, if we allow this, we have to allow people to eat their children's embryos. And if it turns out that eating the embryos does, in fact, give them the child's strength, then what's to stop them from eating other people's embryos? Or even their pre-teens? Imagine the problems that would cause. It's a very slippery slope that we shouldn't head down.
    • I believe both the original poster and the would-be corrector are incorrect. The correct wording would be to substitute "creating" with "using". The embryos used to create stem cell lines are "extras" from fertility treatments. They will be created and destroyed independent of stem cell research.

      Targeting stem cell research is merely a way of winning over voters who dislike what they perceive as the demystifying of "humanity" by science without alienating people who are in favor of fertility treatment

    • At what point do you decern the difference between cells we can destroy and ones we can't? I mean, you wouldn't have any objection to me eating an apple. It is, by your, and many others definition, alive. What is I chopped off my own arm? Am I not allowed to destroy it? It certainly is "alive". More so than the embryos that people are "destroying".

      Would it be murder if I drown a kid that was born with no brain?

      Personally, I think the whole idea of "life" isn't what we should or DO care about
    • Note: I didn't vote for Bush- but I thought his embryonic stem cell policy didn't go far enough.

      Given that- I fully support adult stem cell research, and this is an exciting step merging the two branches. Next step- creating an adult stem cell from a non-stem cell, and researching the difference between the embryonic and the adult stem cells. Either that or figuring out how to remove the 2nd set of DNA from the lab-created embryonic stem cells. Note that embryos aren't the only potential source- cord b
    • This is good. But I'm not clear on what is the benefit when you are starting with a stem cell and ending with a stem cell. How is the new cell different.

      Also, I think the fundamental issue about stem cells and anti-abortion in general is that both sides are not talking about the same thing.

      Pro-Life looks at human life as precious. Without looking at what life is being lived.

      Pro-Choice is looking at when human consciousness and a valuable like begin AND end. Often, they are proponents of the "Right to Die".
    • I fully support embryonic stem cell research. We have embryos that are and will continue to be destroyed today, that could absolutely be harvested for research. However, to ignore any ethical debate on such issues is just as ignorant as some would paint the opposition.

      This is a line I see frequently from people who really should know better. As if nobody was having this debate anyway, as if it wouldn't happened without the President f*ing up research for years.

      What's particularly aggravating about it is

  • Great! (Score:2, Insightful)

    How long till we see anything coemfrom this?
    Months? Nah
    Years? Maybe.
    Decades? Seems to be the most likely.
    Don`t mean to rain on this parade, but if there's one thing that's even slower than game develoment (*cough*DNF*cough*) it's medical research.
  • by RailGunner ( 554645 ) * on Monday August 22, 2005 @12:07PM (#13372756) Journal
    Before anyone starts flaming Christians or George W. Bush - Christians are not opposed to stem cell research - only the source of stem cells being aborted humans. We have no problem with stem cell research when the stem cells come from umbilical cords or adult cadavers.

    Please keep that in mind before you start bitching about us Christians being anti-science.

    • Before anyone starts flaming Christians or George W. Bush - Christians are not opposed to stem cell research - only the source of stem cells being aborted humans. We have no problem with stem cell research when the stem cells come from umbilical cords or adult cadavers. Please keep that in mind before you start bitching about us Christians being anti-science.

      I'd like to explore your belief that all Christians are against using aborted fetuses. I wasn't aware that I was in the midst of the Spokesman o

      • I wasn't aware that I was in the midst of the Spokesman of God and all things Christian.
        That would be the pope... who is also against it ;)
    • mod parent up. There are plenty of sources of stem cells without ethical issues surrounding them.
    • by fireduck ( 197000 ) on Monday August 22, 2005 @12:25PM (#13372892)
      So what is your stance on the destruction of unused embryos at fertility clinics? Why hasn't there been as vocal outcry from Christians regarding that as there has been for stem cells from embryos?
      • by n-baxley ( 103975 ) <nate@baxle y s . org> on Monday August 22, 2005 @12:58PM (#13373168) Homepage Journal
        The objection is that if the use of these embryos for stem cell research is allowed then the demand for them will rise sharply. What then happens when all of the "natural" embryos are used up? There will be money, possibly federal money, available to entice someone into creating more embryos. Now the embryos are not just a byproduct that would have been thrown away anyway, but the product itself. Therein lies the problem. It's currently a byproduct because there is no market for it, but if the market is built the system will be abused.
        • The objection is that if the use of these embryos for stem cell research is allowed then the demand for them will rise sharply... It's currently a byproduct because there is no market for it, but if the market is built the system will be abused.

          So if people enjoy shooting at cars, and occasionally kill someone that's ok, but if we allow salvage companies to make a profit recycling those cars there will be a profit motive and more people will shoot at cars?!?

          What the hell kind of logic is that? Either i

    • Christians are not opposed to stem cell research - only the source of stem cells being aborted humans. We have no problem with

      Hey, as long as you're speaking for all Christians everywhere -- evidently including me and my extended family, despite none of us ever having signed over any plenipotentiary powers to you -- why don't you go ahead and just tell us what God thinks? You're already speaking for other human beings whose minds you plainly DO NOT KNOW; why not go for the Go(l)d?

      See, there's a subtle

  • And another thing... (Score:5, Interesting)

    by imstanny ( 722685 ) on Monday August 22, 2005 @12:08PM (#13372758)
    I just read an article about this, don't know how close it is to this one, but it was stated that the converted stem cells retain the DNA of the doner. The significance of this is that any organ or body part derived from that stem cell could be safely transplanted into that person without fear of rejection. Nifty.
  • Great news! (Score:4, Funny)

    by Swamii ( 594522 ) on Monday August 22, 2005 @12:11PM (#13372775) Homepage
    Even though this is good news for science and the future of medicine, this is Slashdot; I feel like I should start an inflammatory politically charged internet argument that will result in hundreds of follow up posts and lots of angry name-calling.

    So, allow me start us off:
    I hate Bush. Discuss.
  • by Anonymous Coward
    Ooops, I read that as
    "U.S. scientists were successful in creating a new human embryonic stem cell from source."

    Do stem cells run on Linux?
  • Inevitable (Score:2, Interesting)

    by Anonymous Coward
    Science, like life, will always find a way :) Btw with regards to the first post, I believe that the line defining a person varies according to ethical belief, and argument 99.9% of the time in matters involving such belief tend to be pointless. I could make an argument saying that masturbation is mass murder and at the other end, that a child does not qualify as a sentient being. I personally believe neither, but I'd just like to point the futility in arguing such points unless either side is willing to ke
  • by csoto ( 220540 ) on Monday August 22, 2005 @12:14PM (#13372792)
    when we can have baboons, fish and any other creature with eight asses. What a glorious day that will be!
  • Morals vs progress (Score:3, Insightful)

    by Lord_Dweomer ( 648696 ) on Monday August 22, 2005 @12:14PM (#13372798) Homepage
    It is always fascinating to see what holds us back from scientific progress. I'm not saying one side is correct on the issue of stem cell research (although personally I'm all for it) but it really makes you wonder how far we'd be along scientifically if we did not have these debates. Sure, we might all be dead because of it, but we might also be immortal.

    The other fascinating thing to see is what sorts of scientific loopholes people discover to get around these moral issues. In this case, it serves a dual purpose, but interesting nonetheless.

    So at the dreamers end of the scale of possibilities, where do the geneticists on here think we'll be in 10 years once we've charged ahead with developing stem cell research?

    • To me the ethics issue is rather a moot point. Since the laws do not ban those embryos from being aborted, it seems to me that the law has already dealt with the ethical issue. Now what's left is to see whether those embryos will be used for research, and possibly to cure a whole host of disorders, or whether they'll be tossed into the burner with the kidney stones and bandaids.

      This whole debate is simply railing about closing the barn door after the cows have come home. If all these people who find stem

  • From the perspective someone who has had 3 people in their family die of cancer.

    They find it objectionable...fuck'em. Let's see what their attitudes are when their ass is on the line.
    • For starters, I don't think anyone has proposed any use of stem cells to fight cancer. So while I respect the emotion of your position, you seem to have no grasp of the actual specifics of the issues whatsoever. That makes you both passionate and uninformed. A dangerous combination. Putting that aside... My grandfather - who was extremely healthy, relatively young, and whom I was very close to - passed away last summer from stomach cancer. My wife's mother (I actually LIKE my mother-in-law) has been battling breast cancer for 15 years and is currently going through yet another round of chemo. Diseases like this suck, and I hate them. But the truth is that I believe that even if I myself had cancer, I would refuse a treatment that involved using stem cells from an aborted embryo. For the same reason that I would refuse to have my life spared by the killing of an infant, a toddler, or any other human. Sure, you can taunt me and claim that I don't know because I haven't been there and that such high-minded principles fall by the wayside in the struggle for life istelf. But those are my principles, and they are what I beleive in. No matter how bad the experiences in your life have been I think you need to be open to the possibility that other view points can also have compelling motivations and stir up just as much passion as your own. Finally to the argument in general, I'm specifically opposed to stem cells harvested from destroyed embryos. I am also uncomfortable with the use of "discarded" embryos, and I am also uncomfortable with the whole notion of discarding (or even freezing) embryos that are left over from fertility treatments. I say "uncomfortable" and not "opposed" because I think conviction should be a function of both your opinion of the relevant facts and your degree of certainty in the relevant facts. I think it would be good if more people followed that principle.
  • The problem.. (Score:4, Interesting)

    by Renraku ( 518261 ) on Monday August 22, 2005 @12:19PM (#13372848) Homepage
    The problem with stem cells is that conditions must be met for those cells to become differentiated cells.

    Take a skin-type stem cell. It will have to have some kind of trigger to tell it to turn into a skin cell and not say..a nerve cell that attaches to the skin, or an oil-producing-cell, etc. These triggers are tiny, have to be given at the right time, and probably won't be easy to produce.

    Its like having a batch of nano-goop that will eat the resources available and turn itself into an object, but you have to find out how to tell it that, by hand.
  • by Mobile Unit of the G ( 862058 ) on Monday August 22, 2005 @12:20PM (#13372850)
    There's a lot more to the genotype of a somatic cell than DNA: cells accumulate a whole bunch of 'markers' such as methylated bases and proteins stuck to the DNA, and repeat units that fall off the ends of the chromosome with every cell division.

    Nature has good mechanism for making sure germ line (reproductive cells) stay in a good state, but manipulated cells never seem to be 100% right. Clones often end up with poor health and life expectancy because of this, and I'm afraid stem cell therapy will end in poor results, maybe even cancer.

    It's bizzare that stem cells have become such an issue for the left and the right. I see Democrats screaming at the top of their lungs so we can have more research into medical treatments that we can't afford, while Republicans are blowing the ethical issues entirely out of proportion.
  • Just wanted to mention a random fact that I heard about medical research and federal funding.

    Say a company gets federal funds to research cancer, or MS, or any other disease. Most places are involved with the research of many diseases/cures/whatever.

    If one lab, or one person even, involved with that company is researching stem cells, federal funding for ALL projects is cut off. Even if the stem cell research within the company is being funded entirely by private sources.

    It's because of this policy that a
    • What was the source of this information you "heard?" Also a point of clarification. The Bush policy doesn't approve of embryonic stem cell research, not stem cell research as a whole. Everyone gets so torqued up about this subject they fail to differentiate. There are other areas of stem cell research just as promising that don't involve an embryo...
  • by dachshund ( 300733 ) on Monday August 22, 2005 @12:30PM (#13372927)
    I think if there's anything that anti- stem-cell research folks should glean from this, it's that scientists are knocking themselves out looking for alternatives to embryonic stem cell research. These aren't just a few "good guys" or religiously motivated researchers bucking the trend, they're mainstream scientists who are much more concerned with continuing this promising research than they are with winning any sort of debate. This should seem obvious to most people, but listening to the rhetoric on the other side, you might get a very different impression.

    Unfortunately, a lot of this research gets picked up by the anti- side and used as evidence for the (false) view that scientists are just "lazy" or politically motivated, and there are lots of alternatives to embryonic stem cells just lying around if they were willing to use them. Unfortunately, most of these alternatives are not ready for prime time, and won't be for years, maybe decades-- if ever (in fact, you'll see many of them melt away, never to be heard from again once science proves them dangerous or unsatisfactory). Most scientists would like to see this research happening now, because even if it takes decades to result in a cure, a five year head start could mean useable treatments a few years earlier than if we wait. And in some cases, that could save thousands of lives.

    You'll also notice that most of the embryonic stem cell research plans currently being proposed make use of excess embryos from IVF clinics, and only after effort has been expended to reduce over-production and boost embryo adoption (which currently is not very successful, but might take off with enough encouragement). Surprisingly few mainstream politicians and scientists are strongly advocating therapeutic cloning, although that technology has even more promise.

  • by FredThompson ( 183335 ) <fredthompson AT mindspring DOT com> on Monday August 22, 2005 @12:48PM (#13373094)
    Nope, these guys didn't "create" a cell any more than a potter creates clay. They took existing material and manipulated it.
  • What is life? (Score:4, Interesting)

    by PIPBoy3000 ( 619296 ) on Monday August 22, 2005 @01:01PM (#13373183)
    I think the biggest issue here is exactly how people define life. Right now the focus seems to be around "if there's conception, there's life", though there's all sorts of issues that make things complicated. Stem cells from umbilical cords seem fine to most folks because it's something typically seen as tossed away. Extracting bulk stem cells from people's brains is probably a no-no, though stem cells from fat tissue is fine.

    The bottom line is that there's no obvious definition over what constitutes a living person and what isn't. As someone with a master's degree in biology, I've decided there never is going to be one ("life" will be one of those words like "justice" or "freedom" that mean many things to many people).

    What people will find, of course, is that there's a way to reprogram adult cells so that it looks and acts just like embryonic stem cells. Of course, that means that you could turn it into something that looks an awful like a human being. If any cell in your body has the potential for turning into a full-grown human, does that mean liposuction is murder? If I create a stem cell from scratch, can I grow them to term and sell them as non-human slaves?

    I'm not necessarily advocating either side in the debate, only that it's one of those ethical decisions rather than something science dictates as fact. I suspect it'll be argued over for many decades to come.
  • by Stickerboy ( 61554 ) on Monday August 22, 2005 @01:09PM (#13373244) Homepage
    From what I hear, most conservatives base their opposition to embryonic stem cell research based on their belief that life begins at conception, producing a unique organism that God grants a unique soul.

    I have several questions for all of you:

    1) Conception takes place before implantation in the uterus. If you don't already know, many contraceptives work by blocking implantation. Since a conceived zygote is being blocked from developing further (and will die), is this murder?

    2) At the stage the cells are taken from (blastocyst), a biologist could divide the inner cell mass (any one of which is used for embryonic SCR) and what would happen is that twins or triplets would develop. If you believe each child is given a unique soul at conception, does that soul also divide into two or three? Or does God give "last-minute" souls out?

    My point, if it's not clear, is that embryonic stem cells are taken at a stage when it is not individually unique. A lot of people also seem to be happy with either in vitro fertilization or birtch control pills while opposing embryonic stem cell research.
    • by WombatControl ( 74685 ) on Monday August 22, 2005 @01:44PM (#13373567)
      My point, if it's not clear, is that embryonic stem cells are taken at a stage when it is not individually unique. A lot of people also seem to be happy with either in vitro fertilization or birtch control pills while opposing embryonic stem cell research.
      That isn't entirely accurate. A blastocyst is a genetically unique individual, it has DNA that differs from both mother and father. I don't have problems with birth control, since embryos don't always implant naturally. I do have a problem with an environment where human beings become little more than commodities to be exploited. Where's the difference between harvesting "unwanted" children for medical research and ESCR? There are plenty of overpopulated countries where kids would just die of diseases anyway? Why not use them for research? Embryos are genetically unique individuals, which is why they deserve some measure of protection. A society that starts viewing certain human lives as less worthy of protection than others is not a society that's on a healthy ethical footing.
  • Someday is today (Score:4, Insightful)

    by gillbates ( 106458 ) on Monday August 22, 2005 @01:41PM (#13373551) Homepage Journal

    Doctors hope to someday use embryonic stem cells as a source of perfectly matched transplants to treat diseases such as cancer, Parkinson's and some injuries. [emphasis added]

    Currently, doctors are already using adult stem cells to treat diseases such as Parkinson's and some forms of cancer.

    Which lends me to believe that the debate about embrionic stem cell research has very little to do with actually creating cures for diseases. It seems to me that the debate is more about the role of science in society than the actual results it produces. It would seem to some that science is man's highest endeavor, capable of doing no wrong. To them, anything, no matter how horrible, is justifiable in the name of science.

    But what is really interesting is that the opposition to embrionic stem cell research is not an opposition to science or discovery, but rather an affirmation of the dignity of the human being. They see science as the servant of mankind, not mankind as the servant of science. The fundamental objection of embrionic stem cell research is not an objection to discovery, but rather that the research is being done with a secondary objective of allowing science to arbitrarily redefine what it means to be human.

    And this is the fundamental battle over embrionic stem cell research. It has nothing to do with science, and everything to do with removing the role of the church from ethical decisions in public policy.

    Interestingly, I still find it ironic that some people believe there is a conflict between science and religion:

    • Religion finds answers the ethical questions facing all of mankind.
    • Science explains the natural world.
    • Together, with the ethical guidelines provided by religion, and the knowledge provided by science, society can make decisions which preserve both the dignity of the individual and benefit society as a whole.
    I still find it strange that some people believe that science alone can answer all of the questions facing mankind, or that religion alone can sufficiently explain the natural universe. It's all knowledge folks; it enlightens those who are willing to accept it. Insisting that science somehow "proves" God doesn't exist, or that an ancient religious text "scientifically describes" the creation of the world benefits no one and only shows one's ignorance.
  • Nazi research (Score:4, Insightful)

    by John Jorsett ( 171560 ) on Monday August 22, 2005 @01:55PM (#13373657)
    I'd compare this issue to that of the exploitation of Nazi medical "research". Nazi scientists compiled a lot of data on what the limits of human endurance were, such as how much cold could be withstood before death ensued. You can imagine how they acquired that data. There were those who wanted to make use of it, because, after all, the people were dead in any case and perhaps some good could come of it. Others were horrified at the very idea of exploiting data that came with the taint of human suffering.

    If we can benefit from the use of embryonic stem cells without the ethical and moral problems inherent in obtaining them from actual embryos, isn't this a win for both sides of the issue? I submit that anyone who objects at this point isn't interested in medical advancement, but has some other agenda, for which this issue is just a proxy.

"I've finally learned what `upward compatible' means. It means we get to keep all our old mistakes." -- Dennie van Tassel

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