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Science

Cells From Liposuction Function As Stem Cells? 343

texchanchan writes "Plastic surgeon Peter Fodor MD filtered stem cells out of fat sucked from people's oversized body parts, then cultured them into 'bone, cartilage, skeletal muscle and nerve cells.' At the rate of 10,000 stem cells per cm3 that's a lot of stem cells. Combine that with this and you might be on the road to regeneration. And, you can have your stem cells banked for later disasters after your liposuction."
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Cells From Liposuction Function As Stem Cells?

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  • Damn (Score:4, Funny)

    by Spicy Bisquit ( 100885 ) on Thursday May 02, 2002 @03:05PM (#3452521)
    And all this time I have been using it to make plastic explosives. Stupid Brad Pitt.
  • by Husaria ( 262766 ) on Thursday May 02, 2002 @03:05PM (#3452529) Homepage
    The cells that come out of fat are unwanted anyway, so why not just use them. The right really shouldn't have a problem, as long as they don't use it to grow babies for research, otherwise, they'll be howling to the moon, although they probably will anyway..

    • by Drachemorder ( 549870 ) <<brandon> <at> <christiangaming.org>> on Thursday May 02, 2002 @03:10PM (#3452574) Homepage
      Actually, you're wrong. I'm as conservative as they come, and I have no problem with using fat cells for research. Neither do most people I know. I think this sort of research is a good thing because if it works out, I think there would be less pressure to use embryonic stem cells.
  • by fatphil ( 181876 ) on Thursday May 02, 2002 @03:06PM (#3452539) Homepage
    I'm not fat, I'm merely continually regenerating.

    FatPhil
  • Yay! (Score:2, Funny)

    by MarkusH ( 198450 )
    Every 100 cubic centimeters of bone marrow yields up to 10,000 stem cells, Fodor told Reuters Health. But the same amount of fat contains a million stem cells.

    So does this mean the fatter I get, the more stem cells I'll have to repair my body later in life? Quick, somebody hand me that tub of Ben & Jerry's!

  • 10,000? (Score:5, Interesting)

    by AlaskanUnderachiever ( 561294 ) on Thursday May 02, 2002 @03:09PM (#3452562) Homepage
    10,000 per every 100cc is the rate I saw on the article. But even at 100 per cc that's still a lot of stem cells. So even with the total costs you're talking about a nice bank of totally rejection proof stem cells at under 20k. That's almost 1/10 of the price I've seen quoted as a "reasonable estimate" in the last few articles. "attention Kmart shoppers, stem cells kits are now on blue light special!"
  • by EFGearman ( 245715 ) <EFGearmanNO@SPAMsc.rr.com> on Thursday May 02, 2002 @03:12PM (#3452587)
    All my stem cells will be barbecue-flavored.

    EFGearman
  • Joke net (Score:5, Funny)

    by interiot ( 50685 ) on Thursday May 02, 2002 @03:13PM (#3452601) Homepage
    All "For once I'm glad I'm so fat!" jokes, please post under here.
  • by www.sorehands.com ( 142825 ) on Thursday May 02, 2002 @03:13PM (#3452602) Homepage
    A Fat-stem cell donation center. Next to the Red Cross blood donation center.


    Donate your fat cells, get free liposuction, juice, and a cookie.

    • But do you really think the procedure will be free (even if the "body shop" doing it recovers cost + profit from selling the extruded goo)? And do you think liposuction patients will be given a choice as to whether their tissue is sold or discarded? This is people's DNA - will every fat sucking clinic on the planet have license to suck n' sell? Will people be able to get liposuction without having their stem cells harvested and sold? And of course, the all important question - are these stem cells thought to stand a redneck's chance in cabrini green of obviating the need for the pluripotent stem cells, which, to the best of my knowledge, have only been extruded from embryos thus far? I mean, making bone and cartilege is great, but how 'bout skin, or kidneys, or livers? Let's face it - there's not as much need for wholesale replacement of bones as for kidneys.

      • My guess is that people will probably have bits of fat removed from them so that they can use their own genetic material, and not risk rejection and stuff.
    • maybe you're onto something. will we have research facilities offering free lipo to fatties so that they can get all the stem cells they need for their work?
  • ...McDonald's being evil.

    Selling more fatty foods to general population= more sources to harness for stem cells to keep McDonald's executives alive.

    Brilliant.
  • having a fat ass will lead you to the road of health.
  • by Steev ( 5372 )
    Being fat is an evolutionary advantage.
  • I wonder... (Score:2, Insightful)

    I'm a Biology major currently, so I'm right in there with the cloning stuff. I'm rather curious as to how the anti-cloning people are going to react to this; seeing as how the major argument AGAINST stem cell research is the usage of embryos, the use of fat-based stem cells should THEORETICALLY be OK. At least there's a nigh-endless source of fat cells, so we won't have any problem getting raw materials.

    Personally, I'm just waiting for some religious nut to condemn this on the grounds that fat cells have souls. I dunno...if my fat were sentient, I think I'd have a lot more to worry about than just stem cell research.
    • Re:I wonder... (Score:5, Insightful)

      by RailGunner ( 554645 ) on Thursday May 02, 2002 @03:35PM (#3452781) Journal
      I can't speak for all Religious people, but I can certainly speak for myself. (In case you want clarification, I am a Christian. Catholic, more specifically.)

      I'm against embryonic stem cell research, because the stem cells came from aborted human babies, and I personally believe abortion is murder.

      However, I can't see anyone having a problem with stem cell research where the stem cells come from human fat. Nor can I see any reason to oppose stem cell research when the stem cells come from the umbilical cord of a newborn baby.

      If you can, then you are probably also against blood transfusions, organ transplants, and other medical necessities because you mis-read your Bible.

      But please.. not all of us religious people are "nuts". If you are a liberal and think that all religious people are nuts, then maybe you should practice some of that "tolerance" you like to preach about.

      • If you are a liberal and think that all religious people are nuts, then maybe you should practice some of that "tolerance" you like to preach about.

        The only "tolerance" they have is for people who think like they do.

      • What is commonly called "liberalism" in the US is in fact usually something closer to socialism or marxism. True liberals are people like Thomas Jefferson, who was not exactly anti-religion. A true liberal nowadays is usually referred to as a libertarian.

        As far as religion goes, the funny thing is, most "liberals" are in fact very religious. They believe in an entity that they believe should be all knowing, all powerful, in control of everything, and of course always benevolent. I am of course not talking about God but about Government. Nature abhors a vacuum. Liberals are generally athiests (or at least secular and not religious) and so they've simply chosen government as the "higher power" they believe in.

        I've always said that religion stops a thinking mind. Well I'm coming to the conclusion that it is not religion that is stopping anyone from thinking but that there are people out there who cannot or will not think for themselves and that religions is simply one of many crutches that are used by the mentally incompetent to avoid having to deal with reality. Any ideology can be used as such a crutch. The most you can hope for is that the idiots choose an ideology that keeps them out of everyone's hair.

        Lee
    • A `religious nut' wouldn't argue that fat cells have souls. And an atheist can be quite opposed to abortion. Take a look at Libertarians for Life [l4l.org], which present an atheist argument against abortion (and hence, against aborting human beings to collect their stem cells).

      The argument is essentially that there is no dividing line between embryo and human, but rather a continuous progression, just as there is no clear dividing line between infant and man, no point on one side of which we have a baby and on the other side of which we have a productive member of society. Thus abortion is the killing of a human being--one who did not ask to be placed where he is--and thus murder. There is, however, a clear line between gametes and zygote/embryo, and thus contraception is not murder.

      The argument against cloning is essentially that it requires the production of massive number of horribly damaged and diseased men for every whole man it makes. That's not an ethical thing to do.

      So far as organ cloning--who cares? It's a good idea, and I cannot wait until we can do it.

    • I'm rather curious as to how the anti-cloning people are going to react to this; seeing as how the major argument AGAINST stem cell research is the usage of embryos, the use of fat-based stem cells should THEORETICALLY be OK.

      I've never heard anyone voice objections to adult stem cell research such as mentioned in the article above (as opposed to the controversial embryonic stem cell research).

      In fact, I've heard the anti-cloning crowd heartily endorse adult stem cell research as an ethical alternative.
    • Personally, I'm just waiting for some religious nut to condemn this on the grounds that fat cells have souls.

      I probably qualify as a "religious nut." I am pro-life and am opposed to fetal stem-cell research.

      I think this is great! I have a birth defect that resulted in one of my legs being deformed. I get around ok, and many people never notice, but it is a pain to deal with. All my life I've fantasized about being able to chop off my leg and grow a non-deformed one, like a lizard can with its tail. I have no idea if anything like that will happen in my lifetime, but I'm all for research that might make it possible. I just believe it's horribly wrong to kill other humans to do that research (or to use for a potential cure).

      Suck out some fat to get the stem cells? Go for it!

  • In related news: Through selling their fat to science, millions of fat, ugly, poor people became slender, beautiful, rich people, tusly throwing off the delicate natural balance where 90% of the population is unfit (Darwinally speaking) to breed, leading to a previously unimaginable population boom as people proceed to "get it on", which causes widespread overpopulation (although skinny people do admittedly take up significantly less room than their beefier counter-parts), mass starvation (which in a poetic justice sort of way leads to more skinny people, sex, and babies, rinse, lather, repeat), and ultimately the demise of Western Civilization. But what a way to go ;)
  • If I were one of these researchers and I really wanted to show off what this procedure could do, I'd liposuck someone who has had a severe spinal chord injury, liposuck them, and inject the stem cells to the place where the spinal chord is severed, and hopefully watch it grow back together.

    BTW, can you get stem cells to divide in the laboratory and remain stem cells? If so, it seems that the quantity extracted shouldn't matter. This really does sound like a convenient source, though.

  • by morcheeba ( 260908 ) on Thursday May 02, 2002 @03:40PM (#3452827) Journal
    Liposuction fee = $2049
    Stem cell processing = $1200
    Stem cell storage = $100/yr

    The self-storage option begins to look attractive!
  • This is very hopeful! Be your own best friend.... lose some weight via liposuction (get healthier, if the surgery doesn't kill you) and at the same time create a pool of stem cells that can be used to help regenerate yourself and other people (potentially, if everything works out). Now, I'm assuming your own stem cells are most likely more compatible with your own body chemistry, so they'd be the most use in healing you.

    Gee, I hope this pans out.... :) Thin and healthy in one (slightly complex) step....
  • Combine this with (Score:3, Interesting)

    by stoolpigeon ( 454276 ) <bittercode@gmail> on Thursday May 02, 2002 @03:42PM (#3452837) Homepage Journal
    the fact that thin people are 4.8 times more likely to develope ALS [msnbc.com] and I've got to confess that I'm somewhat glad that I haven't kept any of my new years resolutions.
    .
  • "Plastic surgeon Peter Fodor MD filtered stem cells out of fat sucked from people's oversized body parts..." "Combine that with this and you might be on the road to regeneration."

    Yeah... I knew that... I'm not fat, I'm saving up body parts in case I need them.
  • by HorsePunchKid ( 306850 ) <sns@severinghaus.org> on Thursday May 02, 2002 @04:03PM (#3453017) Homepage
    As I understand it, there are (at least) several types of stem cell that form a kind of heirarchy. At the top, there are totipotent stem cells, which can become any cell (more or less) in the human or the placenta. Once those cells differentiate, you get pluripotent stem cells, which can form any kind of tissue in the developing human. The next differentiation leads to various kinds of multipotent stem cells, which each have a more limited set of things they can eventually form. Note that these differentiations are difficult for biologists to control, since you need a rather precise mixture of biological chemicals in the cell's environment for it to turn into what you want it to.

    So anyway, in this particular case, it's great that they can isolate such large quantities of stem cells safely from an adult human, but it's still rather limiting. All those cells will ever be able to form is bone, cartilage, and whatever else that particular type of multipotent cell can give rise to. This is why it's still important to many biologists to be able to collect less-differentiated stem cells. With only that type of cell, we may not be able to learn much about diseases that aren't specifically related to that limited set of tissues. (Though of course there's still a lot left to be learned about even a specific type of multipotent stem cell.)

  • Next time I have to fill out a driver's license application, I can put "fat ass" down in the organ donor questionnaire part and be completely serious about it.
  • The only time when the phrase "I pulled it out of my ass" is not sarcasm.
  • I hereby offer my vast stores of lipids for the benefit of humanity.
  • Cloning theoretically makes men unnecessary.

    Once human cloning has been perfected, and once women figure out how to change the oil in their own cars (*), men are toast.

    (*) Not that all men do; but if you look at the gender breakdown of your average Jiffy Lube you'll know what I mean.
    • Cloning theoretically makes men unnecessary.

      And artificial wombs [slashdot.org] theoretically make women unnecessary. So if we have both, then we don't actually need humans anymore!

      Really, I'm as worried that women will try to make men extinct as I am the other way around. Read: not at all.

  • Looks like Ed Norton & Brad Pitt's soap making business is going to go bankrupt.
  • The whole human race is diagnosed with severe cardiovascular disease and colesteral intolerance not to mention 89% of the pulation being obese and the remaining 11% are overweight.

    Why?

    Seams that an overabundance of those weight-gain genes were distributed in the early 2000 years to fight cancer.

    :-)
  • "These dogs, I tell you, they are so smart, but they worry me sometimes. For instance, I'm plucking this pale yellow cottage cheesy guck from their snouts, rather like cheese atop a microwaved pizza, and I have this horrible feeling, for I suspect these dogs have been rummaging through the dumpsters out behind the cosmetic surgery center again, and their snouts are accessorized with, dare I say, yuppie liposuction fat. How they manage to break into the California state regulation coyote-proof red plastic flesh disposal bags is beyond me. I guess the doctors are being naughty or lazy. Or both. This world. I tell you."

    -- Douglas Coupland, "Generation X"

  • Keep up that sitting and snacking.
  • ...than we thought.

    Not only do THEY last forever, but they might even make you last forever.

    (I suppose we'll see the undertakers filing suit against Hostess any day now...)

"What man has done, man can aspire to do." -- Jerry Pournelle, about space flight

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