Microsoft's new AI diagnostic system achieved 80% accuracy in diagnosing patients compared to 20% for human doctors, while reducing costs by 20%, according to company research published Monday. The MAI Diagnostic Orchestrator queries multiple leading AI models including OpenAI's GPT, Google's Gemini, Anthropic's Claude, Meta's Llama, and xAI's Grok in what the company describes as a "chain-of-debate style" approach.

The system was tested against 304 case studies from the New England Journal of Medicine using Microsoft's Sequential Diagnosis Benchmark, which breaks down each case into step-by-step diagnostic processes that mirror how human physicians work. Microsoft CEO of AI Mustafa Suleyman called the development "a genuine step toward medical superintelligence."

"Earth's ozone layer blocks the Sun's shortest wave radiation, called UV-C, which is so damaging to cells in high doses that it's a go-to sterilizer in hospitals," writes Slashdot reader sciencehabit. "UV-C is such a killer, in fact, that scientists have questioned whether life can survive on worlds that lack an ozone layer, such as Mars or distant exoplanets.

"But research published this month in Astrobiology suggests one hardy lichen, a hybrid organism made of algae and fungi, may have cracked the UV-C code with a built-in sunscreen, despite never experiencing these rays in its long evolutionary history."

Science magazine explains: When scientists brought a sample of the species, the common desert dweller Clavascidium lacinulatum, back to the lab, graduate student Tejinder Singh put the lichen through the wringer. First, Singh dehydrated the lichen, to make sure it couldn't grow back in real time and mask any UV damage. Then he placed the lichen a few centimeters under a UV lamp and blasted it with radiation. The lichen seemed just fine.

So Singh purchased the most powerful UV-C lamp he could find online, capable of sending out 20 times more radiation than the amount expected on Mars. When he tested the lamp on the most radiation-resistant life form on Earth, the bacterium Deinococcus radiodurans, it died in less than a minute. After 3 months—likely the highest amount of UV-C radiation ever tested on an organism—Singh pulled the sample so he could finish his master's thesis in time. About half of the lichen's algal cells had survived. Then, when the team ground up and cultured part of the surviving lichen, about half of its algal cells sprouted new, green colonies after 2 weeks, showing it maintained the ability to reproduce.

The species may provide a blueprint for surviving on Mars or exoplanets, which don't have an ozone layer to protect them.

"Researchers are embarking on an ambitious project to construct human genetic material from scratch," reports the Guardian, "to learn more about how DNA works and pave the way for the next generation of medical therapies." Scientists on the Synthetic Human Genome (SynHG) project will spend the next five years developing the tools and knowhow to build long sections of human genetic code in the lab. These will be inserted into living cells to understand how the code operates.

Armed with the insights, scientists hope to devise radical new therapies for the treatment of diseases. Among the possibilities are living cells that are resistant to immune attack or particular viruses, which could be transplanted into patients with autoimmune diseases or with liver damage from chronic viral infections. "The information gained from synthesising human genomes may be directly useful in generating treatments for almost any disease," said Prof Jason Chin, who is leading the project at the MRC's Laboratory of Molecular Biology (LMB) in Cambridge...

For the SynHG project, researchers will start by making sections of a human chromosome and testing them in human skin cells. The project involves teams from the universities of Cambridge, Kent, Manchester, Oxford and Imperial College London... Embedded in the project is a parallel research effort into the social and ethical issues that arise from making genomes in the laboratory, led by Prof Joy Zhang at the University of Kent. "We're a little way off having anything tangible that can be used as a therapy, but this is the time to start the discussion on what we want to see and what we don't want to see," said Dr Julian Sale, a group leader at the LMB.

Just four weeks after an early June flight to the edge of space, Blue Origin has again carried six more passengers there and back again, reports CBS News, noting that the 10-minute ride was Blue Origin's 13th flight "out of the discernible atmosphere." The New Shepard capsule's stubby single-stage booster roared to life just after 9:38 a.m. EDT, throttled up to full thrust and smoothly climbed away from Blue Origin's launch site near Van Horn, Texas. The hydrogen-fueled BE-3 engine powering the New Shepard fired for about two-and-a-half minutes, accelerating the spacecraft to just under three times the speed of sound.

The capsule then separated from the booster and continued coasting upward along its up-and-down trajectory. At that point, the passengers — Allie and Carl Kuehner, Leland Larson, Freddie Rescigno Jr., Jim Sitkin and Owolabi Salis, the first Nigerian to fly in space — began enjoying about three minutes of weightlessness. Free to unstrap and float about the cabin, the passengers were able to take in the view through the largest windows in any operational spacecraft as the ship climbed to an altitude of just above 65 miles. That's about three miles higher than the internationally recognized boundary between the discernible atmosphere and space.

The capsule then began falling back to Earth and the passengers returned to their seats for the descent to touchdown. The reusable booster, meanwhile, made its own return to the launch site, dropping tail first to a rocket-powered touchdown... The company has now launched 74 passengers, including Bezos' wife Lauren Sánchez, and four who have flown twice.
By April nearly 120 civilians had already travelled to the edge of space, CBS News reported earlier — while Virgin Galactic is expected to resume flights next year.

You can replay the webcast of the mission on Blue Origin's YouTube channel.

In its first 10 hours the Rubin space telescope found 2,104 never-before-seen asteroids in our solar system. And Gizmodo reports the data went directly to the International Astronomical Union's Minor Planet Center (MPC), which "plays an essential role in the early detection and monitoring of asteroids that threaten Earth." The MPC has spent years preparing for the deluge of data from Rubin, ramping up its software to process massive amounts of observations. When the first round officially came flooding in on Monday, it was "nerve-racking and exciting simultaneously," Matthew Payne, MPC director, told Gizmodo.
But Space.com explains how extraordinary that is. "There are approximately a million known asteroids in our cosmic neighborhood; over the next few years, Rubin could very well hike that figure up to five million." "This is five times more than all the astronomers in the world discovered during the last 200 years since the discovery of the first asteroid," Željko IveziÄ, Deputy Director of Rubin's Legacy Survey of Space and Time, said during the conference. "We can outdo two centuries of effort in just a couple of years...." The plan is for Rubin to capture such massive, high-resolution images of the southern sky once every three nights for at least the next 10 years. You can therefore consider it to be a super-fast, super-efficient and super-thorough cosmic imager. Indeed, those qualities are perfect for spotting some of the smallest details trailing through the space around our planet: asteroids. "We make movies of the night sky to see two things: objects that move and objects that change brightness," IveziÄ said. "Objects that move come in two flavors. Stars in our galaxy move, and they move slowly. Much faster objects are asteroids...."

[I]t's tremendously difficult to record an asteroid at all. "Asteroids, they disappear after you get one picture of them," IveziÄ said, calling Rubin's ability to image small objects orbiting the sun "unprecedented."
Space.com notes that the ten million galaxies in its first image are just 0.05% of around 20 billion galaxies that Rubin will have imaged by the end of its 10-year "Legacy Survey of Space and Time" investigating dark energy.

In fact, in its first year of regular operations, the Observation "will collect more data than all previous optical observatories combined," reports Earth.com. That torrent of information — petabytes of images and catalogs — will be processed in near-real time. Alerts will be issued to the worldwide astronomy community within 60 seconds of any detected change in the sky. By democratizing access to its enormous dataset, Rubin Observatory will empower both professionals and citizen scientists. This will foster discoveries that range from mapping the structure of the Milky Way to refining the rate at which the universe is expanding.
Reuters explains just how much data is being generated: The number of alerts the telescope will send every night is equivalent to the inboxes of 83,000 people. It's impossible for someone to look at that one by one," said astrophysicist Francisco Foster. "We're going to have to use artificial intelligence tools."
And New Atlas shares some of the "first look" videos released by the Observatory, including one titled The Cosmic Treasure Chest and another on the Trifid and Lagoon Nebulae (which Space.com describe as clouds of gas and dust condensing to birth new stars).

"It has long been unclear when humans started using fire," writes Phys.org... To address this question, researchers from the Institute of Oceanology of the Chinese Academy of Sciences (IOCAS), alongside collaborators from China, Germany, and France, analyzed the pyrogenic carbon record in a 300,000-year-old sediment core from the East China Sea. "Our findings challenge the widely held belief that humans only began influencing the environment with fire in the recent past, during the Holocene," said Dr. Zhao Debo, the study's corresponding author.

This study, published in the Proceedings of the National Academy of Sciences, highlights the presence of charred plant remains — known as pyrogenic carbon — formed when vegetation burns but is not completely consumed by fire. The research reveals a notable increase in fire activity across East Asia approximately 50,000 years ago. This finding aligns with earlier reports of heightened fire activities in Europe, Southeast Asia, and the Papua New Guinea-Australia region respectively, suggesting a continental-scale intensification of fire use during this period... The study highlights that this global rise in fire use coincides with the rapid spread of Homo sapiens, increasing population densities, and a greater reliance on fire, particularly amid cold, glacial conditions...

These conclusions have significant implications for understanding Earth's sensitivity to human impacts. If human fire management altered atmospheric carbon levels tens of thousands of years ago, current climate models may underestimate the historical baseline of human-environment interactions.

An anonymous reader shared this report from Smithsonian magazine: Last year, Australian scientists picked up a mysterious burst of radio waves that briefly appeared brighter than all other signals in the sky. Now, the researchers have discovered the blast didn't come from a celestial object, but a defunct satellite orbiting Earth... "We got all excited, thinking maybe we'd discovered a new pulsar or some other object," says Clancy James, a researcher at Australia's Curtin University who is on the Australian Square Kilometer Array Pathfinder (ASKAP) team, to Alex Wilkins at New Scientist. After taking a closer look, however, the team realized that the only viable source for the burst was NASA's dead Relay 2, a short-lived satellite that hasn't been in operation since 1967....

The researchers also discovered that at the time of the event, the satellite was only around 2,800 miles away from Earth, which explains why the signal appeared so strong. The reason behind Relay 2's sudden burst is not clear, but the team has come up with two potential explanations — and neither involves the satellite coming back to life like a zombie. One relates to electrostatic discharge — a build-up of electricity that can result in a sudden blast. Spacecraft get charged with electricity when they pass through plasma, and once enough charge accumulates, it can create a spark. "New spacecraft are built with materials to reduce the build-up of charge, but when Relay 2 was launched, this wasn't well-understood," explains James to Space.com's Robert Lea. The other idea is that a micrometeorite hit the satellite, releasing a small cloud of plasma and radio waves.

Karen Aplin, a space scientist at the University of Bristol in England who was not involved in the study, tells New Scientist that it would be tough to differentiate between signals produced by each of those two scenarios, because they would look very similar. The researchers say they favor the first idea, however, because micrometeorites the size of the one that could have caused the signal are uncommon.
"Their findings were published in a pre-print paper on the arXiv server that has not yet been peer-reviewed."

On the International Space Station, air has been slowly leaking out for years from a Russia-controlled module, reports CNN. But recently "station operators realized the gradual, steady leak had stopped. And that raised an even larger concern." It's possible that efforts to seal cracks in the module's exterior wall have worked, and the patches are finally trapping air as intended. But, according to NASA, engineers are also concerned that the module is actually holding a stable pressure because a new leak may have formed on an interior wall — causing air from the rest of the orbiting laboratory to begin rushing into the damaged area. Essentially, space station operators are worried that the entire station is beginning to lose air.

Much about this issue is unknown. NASA revealed the concerns in a June 14 statement. The agency said it would delay the launch of the private Ax-4 mission, carried out by SpaceX and Houston-based company Axiom Space, as station operators worked to pinpoint the problem. "By changing pressure in the transfer tunnel and monitoring over time, teams are evaluating the condition of the transfer tunnel and the hatch seal," the statement read.

More than a week later, the results of that research are not totally clear. After revealing the new Wednesday launch target Monday night, NASA said in a Tuesday statement that it worked with Roscosmos officials to investigate the issue. The space agencies agreed to lower the pressure in the transfer tunnel, and "teams will continue to evaluate going forward," according to the statement... The cracks are minuscule and mostly invisible to the naked eye, hence the difficulty attempting to patch problem areas.
Axiom Space launched four astronauts to the International Space Station on Wednesday.

But its four-person crew had previously "remained locked in quarantine in Florida for about a month, waiting for their chance to launch," notes CNN, as NASA and the Russian space agency Roscosmos "attempted to sort through" the leak issue.

Seven people have now received Neuralink's N1 brain implant, which enables individuals with ALS or spinal cord injuries to control a computer with their thoughts. PCMag reports: In a February 2025 update, Neuralink confirmed that three people had received its brain-computer interface (BCI). That increased to five by June, when it also reported a $650 million funding round. We're now at seven, Barrow tweeted today; Neuralink retweeted that message.

Six of the seven are participating in the PRIME study, conducted by Barrow, which handles the implantations from its Phoenix, Arizona, office. It aims to prove that the N1 implant, the R1 surgical robot, and the N1 User App on the computer are safe and effective, according to the program brochure. (No BCIs have been approved by the US Food and Drug Administration.)

Participants in the study get the implant through a surgery in which a custom-built robotic arm drills a hole in their skull and implants the device. The implant connects to a computer via Bluetooth, allowing patients to move the cursor, select words to type, browse the web, and even play video games -- a favorite activity of Neuralink's first human patient, Noland Arbaugh, who can do this all without moving any limbs or fingers. [...] Arbaugh, now 31, became paralyzed during a diving accident. Other Neuralink patients include Alex, a former machine parts builder who lost function of his arms and uses his N1 Implant to design 3D machine parts with computer-aided design (CAD). The third patient is Brad, the first person with ALS to receive the N1 implant, according to Barrow.

Mike is the fourth patient, and "the first person with a full-time job to use the N1 Implant," Barrow says. "He worked as a survey technician for city government and spent the majority of his time in the field until his ALS made the work too difficult. Like Alex, Mike has used CAD software with his Neuralink device to continue doing survey work from home and provide for his family." The fifth publicly named patient is RJ, a veteran who became paralyzed after a motorcycle accident, according to the University of Miami. The other two patients remain anonymous, but we can expect Neuralink to continue recruiting more people (here's how to apply).

A new study challenges previous research about which sleep stages help people achieve breakthrough moments in problem-solving. Researchers found that N2 sleep, a deeper stage of non-REM sleep, significantly increased participants' likelihood of experiencing sudden insights during a perceptual task. The preregistered study involved 90 participants who performed a visual pattern recognition task before and after a 20-minute daytime nap while researchers monitored their brain activity with EEG.

Participants who reached N2 sleep showed an 85.7% rate of achieving insights about a hidden strategy in the task, compared to 63.6% for those who only reached N1 sleep (the first stage of non-rapid eye movement sleep) and 55.5% for participants who remained awake. The findings contradict earlier work by Lacaux and colleagues, which suggested that lighter N1 sleep promoted insight while deeper sleep hindered it.

News coverage: Stuck on a problem? Take a nap!

alternative_right shares a report from Phys.Org: A new study from the University of Bath's School of Management has found that individuals with a higher IQ make more realistic predictions, which supports better decision-making and can lead to improved life outcomes. The research, published in the Journal of Personality and Social Psychology, shows that people with a low IQ (the lowest 2.5% of the population) make forecasting errors that are more than twice as inaccurate as those made by people with a high IQ (the top 2.5% of the population).

The research used data from a nationally representative sample of people over 50 in England (English Longitudinal Study of Aging ELSA), assessing their ability to predict their own life expectancy. Individuals were asked to predict their probability of living to certain ages, and these estimates were compared with the probabilities taken from Office for National Statistics life tables (a demographic tool used to analyze death rates and calculate life expectancies at various ages). The study controlled for differences in lifestyle, health, and genetic longevity.

By analyzing participants' scores on a variety of cognitive tests, as well as genetic markers linked to intelligence and educational success, Chris Dawson, Professor of Economics and Behavioral Science at the University of Bath, showed that smarter individuals tend to have more accurate beliefs about uncertain future events - they are more skilled at assessing probability. Individuals with a higher IQ are significantly better at forecasting, making fewer errors (both positive and negative) and showing more consistent judgment compared to those with a lower IQ.

An anonymous reader quotes a report from Neuroscience News Science Magazine: Surgeons have performed the first fully robotic heart transplant in the U.S., using advanced robotic tools to avoid opening the chest. [...] Using a surgical robot, lead surgeon Dr. Kenneth Liao and his team made small, precise incisions, eliminating the need to open the chest and break the breast bone. Liao removed the diseased heart, and the new heart was implanted through preperitoneal space, avoiding chest incision.

"Opening the chest and spreading the breastbone can affect wound healing and delay rehabilitation and prolong the patient's recovery, especially in heart transplant patients who take immunosuppressants," said Liao, professor and chief of cardiothoracic transplantation and circulatory support at Baylor College of Medicine and chief of cardiothoracic transplantation and mechanical circulatory support at Baylor St. Luke's Medical Center. "With the robotic approach, we preserve the integrity of the chest wall, which reduces the risk of infection and helps with early mobility, respiratory function and overall recovery."

In addition to less surgical trauma, the clinical benefits of robotic heart transplant surgery include avoiding excessive bleeding from cutting the bone and reducing the need for blood transfusions, which minimizes the risk of developing antibodies against the transplanted heart. Before the transplant surgery, the 45-year-old patient had been hospitalized with advanced heart failure since November 2024 and required multiple mechanical devices to support his heart function. He received a heart transplant in early March 2025 and after heart transplant surgery, he spent a month in the hospital before being discharged home, without complications.

The James Webb Space Telescope has discovered its first new exoplanet, TWA 7b -- a young, low-mass planet about 100 times the mass of Earth, making it the lightest planet ever directly imaged beyond the solar system. Space.com reports: TWA 7b was discovered in the debris rings that surround the low-mass star CE Antilae, also known as TWA 7, located around 111 light-years from Earth. CE Antilae is a very young star, estimated to be around just a few million years old. If that seems ancient, consider the sun, a "middle-aged" star, is around 4.6 billion years old.

[...] The disk of CE Antilae is divided into three distinct rings, one of which is narrow and bounded by two empty "lanes" mostly devoid of matter. When imaging this ring, the JWST spotted an infrared-emitting source, which the team of astronomers determined is most likely a young exoplanet. They then used simulations that confirmed the formation of a thin ring and a "hole" exactly where this planet is positioned, corresponding to JWST observations. The research has been published in the journal Nature.

An anonymous reader quotes a report from The Guardian: Swarms of tiny robots, each no larger than a speck of dust, could be deployed to cure stubborn infected sinuses before being blown out through the nose into a tissue, researchers have claimed. The micro-robots are a fraction of the width of a human hair and have been inserted successfully into animal sinuses in pre-clinical trials by researchers at universities in China and Hong Kong. Swarms are injected into the sinus cavity via a duct threaded through the nostril and guided to their target by electromagnetism, where they can be made to heat up and catalyze chemical reactions to wipe out bacterial infections. There are hopes the precisely targeted technology could eventually reduce reliance on antibiotics and other generalized medicines.

[...] The latest breakthrough, based on animal rather than human trials, involves magnetic particles "doped" with copper atoms which clinicians insert with a catheter before guiding to their target under a magnetic field. The swarms can be heated up by reacting to light from an optical fibre that is also inserted into the body as part of the therapy. This allows the micro-robots to loosen up and penetrate viscous pus that forms a barrier to the infection site. The light source also prompts the micro-robots to disrupt bacterial cell walls and release reactive oxygen species that kill the bacteria.

The study, published in Nature Robotics, showed the robots were capable of eradicating bacteria from pig sinuses and could clear infections in live rabbits with "no obvious tissue damage." The researchers have produced a model of how the technology could work on a human being, with the robot swarms being deployed in operating theatre conditions, allowing doctors to see their progress by using X-rays. Future applications could include tackling bacterial infections of the respiratory tract, stomach, intestine, bladder and urethra, they suggested. "Our proposed micro-robotic therapeutic platform offers the advantages of non-invasiveness, minimal resistance, and drug-free intervention," they said.

Overfishing has led to a collapse in the eastern Baltic cod population, but over the past three decades the size of the fish themselves has also been dramatically and mysteriously shrinking. From a report: Now scientists have uncovered genomic evidence that intensive fishing has driven rapid evolutionary changes that have contributed to these fish roughly halving in average body length since the 1990s. The "shrinking" of cod, from a median mature body length of 40cm in 1996 to 20cm in 2019, has a genetic basis and human activities have left a profound mark on the population's DNA, the study concluded.

[...] The dramatic shrinking of cod has been a source of concern for several decades, but it was not clear to what extent the phenomenon has been driven by environmental factors such as hypoxic conditions caused by algal blooms, pollution and more extreme marine seasonal temperature changes. [...] The study used an archive of tiny ear bones, called otoliths, of 152 cod, caught in the Bornholm Basin between 1996 and 2019. Otoliths -- a bit like tree rings -- record annual growth, making them valuable biological timekeepers.

A groundbreaking stem cell treatment developed by Vertex Pharmaceuticals has allowed 10 out of 12 patients with severe type 1 diabetes to stop insulin therapy after one year. While the trial included some side effects and two unrelated deaths, the results mark a major step forward and have progressed to phase 3 clinical testing. ScienceAlert reports: The pancreas's islet cells are responsible for maintaining most of our bodies' insulin levels. Donor transplants of healthy versions of these cells have shown promise in treating type 1 diabetes in the past, but multiple donors are required, and donors are rare. So University of Toronto surgeon Trevor Reichman and colleagues infused 12 patients with islet cells derived from human stem cells in a treatment known as zimislecel. The patients also received immunosuppressive treatment before and after their zimislecel infusion. The islets not only produced insulin inside their bodies, but they did so at safe levels, reducing the patients' dependence on costly doses of insulin. "These findings showed that zimislecel islet cells were functional and self-regulated appropriately," the researchers write in their paper.

The mild to moderate side-effects, including decreased kidney function and the anticipated drop in immune cells, were all linked with the immunosuppressive therapy. Sadly, two additional participants died during the trial; one from an infection arising from surgery and the other from complications due to an unrelated condition. As there were no serious adverse events attributed to the new islet cell therapy, the clinical trials are have progressed into phase 3. "These findings provide evidence that pancreatic islets can be effectively produced from pluripotent stem cells and used to treat type 1 diabetes," Reichman and team conclude. The research has been published in the journal NEJM.

alternative_right shares a report from Phys.Org: In new research published by scientists studying fission yeastâ"a single-celled organism surprisingly similar to human cellsâ"researchers found that caffeine affects aging by tapping into an ancient cellular energy system. A few years ago, the same research team found that caffeine helps cells live longer by acting on a growth regulator called TOR (target of rapamycin). TOR is a biological switch that tells cells when to grow, based on how much food and energy is available. This switch has been controlling energy and stress responses in living things for over 500 million years. But in their latest study, the scientists made a surprising discovery: Caffeine doesn't act on this growth switch directly. Instead, it works by activating another important system called AMPK, a cellular fuel gauge that is evolutionarily conserved in yeast and humans.

"When your cells are low on energy, AMPK kicks in to help them cope," explains Dr. Charalampos (Babis) Rallis, Reader in Genetics, Genomics and Fundamental Cell Biology at Queen Mary University of London, the study's senior author. "And our results show that caffeine helps flip that switch." Interestingly, AMPK is also the target of metformin, a common diabetes drug that's being studied for its potential to extend human lifespan together with rapamycin. Using their yeast model, the researchers showed that caffeine's effect on AMPK influences how cells grow, repair their DNA, and respond to stress -- all of which are tied to aging and disease. The study has been published in the journal Microbial Cell.

More than 110 million people across Europe suffer high levels of health-damaging noise pollution, according to a report. The resulting physiological stress and sleep disturbance leads to 66,000 early deaths a year and many cases of heart disease, diabetes and depression. The Guardian: The report, from the European Environment Agency (EEA), focuses on noise from cars, trains and aeroplanes and found that 20% of the population of the European Economic Area (EEA) were affected. Separate research, using a slightly lower threshold for dangerous noise pollution, found that 40% of the UK population were exposed to harmful transport noise.

Seventeen million people endure particularly high noise pollution -- "long-term, high-annoyance" -- and almost 5 million suffer "severe" sleep disturbance. Fifteen million children live in areas of harmful noise. The harm to health from noise is greater than that from higher-profile risks including secondhand tobacco smoke or lead exposure, and incurs an economic cost of almost $116bn a year, the analysis found.

The damage to health is likely to be an underestimate, the researchers said. Using the World Health Organization's stricter threshold for risky noise pollution gives an estimate of 150 million people across Europe exposed. The EU's target to cut the number of people chronically disturbed by transport noise by 30% by 2030 will not be met without further action, the researchers said.

The number of doctoral graduates globally has grown steadily over recent decades, creating a massive imbalance between PhD holders and available academic positions. Among the 38 OECD countries, new doctorate holders almost doubled between 1998 and 2017.

China's doctoral enrollment has exploded from around 300,000 students in 2013 to more than 600,000 in 2023. This growth has forced PhD graduates into non-academic careers at unprecedented rates. A 2023 study of more than 4,500 PhD graduates in the United Kingdom found over two-thirds were employed outside academia.

In South Africa, 18% of more than 6,000 PhD graduates reported difficulty finding jobs related to their expertise. Some countries have begun adapting their doctoral programs. Japan, Germany and the United Kingdom now offer training and paid internships during doctoral studies, including "industrial PhD" programs where students conduct research in collaboration with companies.

Bacteria can be used to turn plastic waste into painkillers, researchers have found, opening up the possibility of a more sustainable process for producing the drugs. From a report: Chemists have discovered E coli can be used to create paracetamol, also known as acetaminophen, from a material produced in the laboratory from plastic bottles. "People don't realise that paracetamol comes from oil currently," said Prof Stephen Wallace, the lead author of the research from the University of Edinburgh. "What this technology shows is that by merging chemistry and biology in this way for the first time, we can make paracetamol more sustainably and clean up plastic waste from the environment at the same time."

Writing in the journal Nature Chemistry, Wallace and colleagues report how they discovered that a type of chemical reaction called a Lossen rearrangement, a process that has never been seen in nature, was biocompatible. In other words, it could be carried out in the presence of living cells without harming them. The team made their discovery when they took polyethylene terephthalate (PET) -- a type of plastic often found in food packaging and bottles -- and, using sustainable chemical methods, converted it into a new material.