An anonymous reader quotes a report from the Guardian: The critical Atlantic current system appears significantly more likely to collapse than previously thought after new research found that climate models predicting the biggest slowdown are the most realistic. Scientists called the new finding "very concerning" as a collapse would have catastrophic consequences for Europe, Africa and the Americas. The Atlantic meridional overturning circulation (Amoc) is a major part of the global climate system and was already known to be at its weakest for 1,600 years as a result of the climate crisis. Scientists spotted warning signs of a tipping point in 2021 and know that the Amoc has collapsed in the Earth's past.

Climate scientists use dozens of different computer models to assess the future climate. However, for the complex Amoc system, these produce widely varying results, ranging from some that indicate no further slowdown by 2100 to those suggesting a huge deceleration of about 65%, even when carbon emissions from fossil fuel burning are gradually cut to net zero. The research combined real-world ocean observations with the models to determine the most reliable, and this hugely reduced the spread of uncertainty. They found an estimated slowdown of 42% to 58% in 2100, a level almost certain to end in collapse.

The Amoc is a major part of the global climate system and brings sun-warmed tropical water to Europe and the Arctic, where it cools and sinks to form a deep return current. A collapse would shift the tropical rainfall belt on which many millions of people rely to grow their food, plunge western Europe into extreme cold winters and summer droughts, and add 50-100cm to already rising sea levels around the Atlantic. The slowdown has to do with the Arctic's rapidly rising temperatures from global warming. "Warmer water is less dense and therefore sinks into the depths more slowly," explains the Guardian. "This slowing allows more rainfall to accumulate in the salty surface waters, also making it less dense, and further slowing the sinking and forming an Amoc feedback loop."

The new research has been published in the journal Science Advances.

An anonymous reader quotes a report from Ars Technica: On Thursday, OpenAI announced it had developed a large language model specifically trained on common biology workflows. Called GPT-Rosalind after Rosalind Franklin, the model appears to differ from most science-focused models from major tech companies, which have generally taken a more generic approach that works for various fields. In a press briefing, Yunyun Wang, OpenAI's Life Sciences Product Lead, said the system was designed to tackle two major roadblocks faced by current biology researchers. One is the massive datasets created by decades of genome sequencing and protein biochemistry, which can be too much for any one researcher to take in. The second is that biology has many highly specialized subfields, each with its own techniques and jargon. So, for example, a geneticist who finds themselves working on a gene that's active in brain cells might struggle to understand the immense neurobiological literature.

Wang said the company had taken an LLM and trained it on 50 of the most common biological workflows, as well as on how to access the major public databases of biological information. Further training has resulted in a system that can suggest likely biological pathways and prioritize potential drug targets. "We're connecting genotype to phenotype through known pathways and regulatory mechanisms, infer likely structural or functional properties of proteins, and really leveraging this mechanistic understanding," Wang said. To address LLMs' tendencies toward sycophancy and overenthusiasm, OpenAI says it has tuned the model to be more skeptical, so it's more likely to tell you when something is a bad drug target. There was a lot of talk about GPT-Rosalind's "reasoning" and "expert-level" abilities. We were told that the former was defined as being able to work through complex, multi-step processes, while the latter was derived from the model's performance on a handful of benchmarks. Access to GPT-Rosalind is currently limited "due to concerns about the model's potential for harmful outputs if asked to do something like optimize a virus's infectivity," notes Ars. Only U.S.-based organizations can request access at the moment.

An anonymous reader quotes a report from the Guardian: We may appear to have little in common with sperm whales – enormous, ocean-dwelling animals that last shared a common ancestor with humans more than 90 million years ago. But the whales' vocalized communications are remarkably similar to our own, researchers have discovered. Not only do sperm whale have a form of "alphabet" and form vowels within their vocalizations but the structure of these vowels behaves in the same way as human speech, the new study has found.

Sperm whales communicate in a series of short clicks called codas. Analysis of these clicks shows that the whales can differentiate vowels through the short or elongated clicks or through rising or falling tones, using patterns similar to languages such as Mandarin, Latin and Slovenian. The structure of the whales' communication has "close parallels in the phonetics and phonology of human languages, suggesting independent evolution," the paper, published in the Proceedings B journal, states. Sperm whale coda vocalizations are "highly complex and represent one of the closest parallels to human phonology of any analyzed animal communication system," it added.

[...] The new study shows that "sperm whale communication isn't just about patterns of clicks -- it involves multiple interacting layers of structure," said Mauricio Cantor, a behavioral ecologist at the Marine Mammal Institute who was not involved in the research. "With this study, we're starting to see that these signals are organized in ways we didn't fully appreciate before." The latest discovery around sperm whale speech has inched forward the possibility of someday fully understanding the creatures and even communicating with them. Project CETI has set a goal of being able to comprehend 20 different vocalized expressions, relating to actions such as diving and sleeping, within the next five years. A future where we're able to fully understand what the whales are saying and be able to have a conversation with them is "totally within our grasp," said David Gruber, founder and president of Project CETI. "We've already got a lot further than I thought we could. But it will take time, and funding. At the moment we are like a two-year-old, just saying a few words. In a few years' time, maybe we will be more like a five-year-old."

An anonymous reader quotes a report from UploadVR: A group of independent researchers built a device that can artificially induce smell using ultrasound, with no consumable cartridges required. [...] The team of four are Lev Chizhov, Albert Yan-Huang, Thomas Ribeiro, Aayush Gupta. Chizhov is a neurotech entrepreneur with a background in math and physics, Yan-Huang is a researcher at Caltech with a background in computation and neural systems, and Ribeiro and Gupta are co-researchers on the project with software engineering and AI expertise.

Instead of targeting your nose at all, the device directly targets the olfactory bulb in your brain with "focused ultrasound through the skull." The researchers say that as far as they're aware, no one has ever done this before, even in animals. A challenge in targeting the olfactory bulb is that it's buried behind the top of your nose, and your nose doesn't provide a flat surface for an emitter. Ultrasound also doesn't travel well through air. The solution the researchers came up with was to place the emitter on your forehead instead, with a "solid, jello-like pad for stability and general comfort," and the ultrasound directed downward towards the olfactory bulb.

To determine the best placement, they say they used an MRI of one of their skulls to "roughly determine where the transducer would point and how the focal region (where ultrasound waves actually concentrate) aligned with the olfactory bulb (the target for stimulation)". [...] According to the researchers, they were able to induce the sensation of fresh air "with a lot of oxygen", the smell of garbage "like few-day-old fruit peels," an ozone-like sensation "like you're next to an air ionizer," and a campfire smell of burning wood. While technically head-mounted, the current device does require being held up with two hands. But as with all such prototypes, it likely could be significantly miniaturized.

An anonymous reader quotes a report from the New York Times: Many scientists have contended that humans have evolved very little over the past 10,000 years. A few hundred generations was just a blink of the evolutionary eye, it seemed. Besides, our cultural evolution -- our technology, agriculture and the rest -- must have overwhelmed our biological evolution by now. A vast study, published on Wednesday in the journal Nature, suggests the opposite. Examining DNA from 15,836 ancient human remains, scientists found 479 genetic variants that appeared to have been favored by natural selection in just the past 10,000 years.

The researchers also concluded that thousands of additional genetic variants have probably experienced natural selection. Before the new study, scientists had identified only a few dozen variants. "There are so many of them that it's hard to wrap one's mind around them," said David Reich, a geneticist at Harvard Medical School and an author of the new study. He and his colleagues found that a mutation that is a major risk factor for celiac disease, for example, appeared just 4,000 years ago, meaning the condition may be younger than the Egyptian pyramids. The mutation became ever more common. Today, an estimated 80 million people worldwide have celiac disease, in which the immune system attacks gluten and damages the intestines.

The steady rise of the mutation came about through natural selection, the scientists argue. For some reason, people with the mutation had more descendants than people without it -- even though it put them at risk of an autoimmune disorder. Other findings are even more puzzling. The researchers found that genetic variants that raise the odds of a smoking habit have been getting steadily rarer in Europe for the past 10,000 years. Something is working against those variants -- but it can't be the harm from smoking. Europeans have been smoking tobacco for only about 460 years. The scientists can't see from their research so far what forces might be making these variants more or less common. "My short answer is, I don't know," said Ali Akbari, a senior staff scientist at Harvard and an author of the study. The researchers also found that some variants, like the one linked to Type B blood, became much more common in Europe around 6,000 years ago, while others changed direction over time. For example, a TYK2 immune gene variant that may have once been beneficial later became harmful because it increased tuberculosis risk.

The study also found signs of natural selection in 44 out of 563 traits. Variants linked to Type 2 diabetes, wider waists, and higher body fat have become less common, possibly because farming and carbohydrate-heavy diets made once-useful fat-storing traits more harmful. Other findings, such as selection favoring genes linked to more years of schooling, are harder to interpret.

A 63-year-old man in Norway appears to be cured of HIV after receiving a stem cell transplant from his brother, who turned out to have a rare mutation that makes immune cells resistant to HIV. "Four years after the transplant, and two years after the man stopped antiretroviral therapy, he still appears to be free of the infection," reports Gizmodo. From the report: According to the report, the man was first diagnosed with myelodysplastic syndrome, a type of cancer that weakens blood cell production from bone marrow, in 2018. Though he seemed to initially respond to treatment, the cancer returned after two years, and doctors decided to perform a stem cell transplant. Because the man also had HIV (diagnosed in 2006), the doctors were hoping to treat both conditions at once, though they knew their chances were low. Most of these cases have involved the use of stem cells taken from people with two copies of a particular mutation in their CCR5 gene, which regulates the CC5R receptor on white blood cells. This mutation, named CCR5-delta 32, makes immune cells naturally resistant to infection from strains of HIV-1 (the most common type of the virus). However, only about 1% of the population carries two copies of the mutation.

After initial screening failed to find someone who both possessed the mutation and had compatible bone marrow, the doctors decided to move ahead with the man's brother, who was already known to have compatible bone marrow. But to everyone's surprise, testing on the day of the transplant showed that the brother also had the mutation. Though the man did experience some complications from the procedure, his body successfully started to produce new blood cells with the mutation. The doctors decided to take him off antiretroviral medication two years after the transplant. And in the two years since then, regular follow-up tests have failed to show any signs of the virus in his system. [...] According to AFP, there have only been roughly 10 cases worldwide involving an HIV cure through stem cell transplantation. This is the first to involve a family donor.

Researchers at the University of Southern California say they've developed a memristor memory device that continued operating at 700 degrees Celsius. "And crucially, 700 degrees was not the limit, it was simply as hot as their testing equipment could go," adds ScienceAlert. "The device showed no signs of failing." From the report: The device is called a memristor and it's a nanoscale component that can both store information and perform computing operations. Think of it as a tiny sandwich with two electrode layers on the outside and a thin ceramic filling in the middle. The team built theirs from tungsten, the metal with the highest melting point of any element, combined with a ceramic called hafnium oxide, and with a layer of graphene at the bottom. Each material can withstand enormous heat. Together, they turned out to be extraordinary.

What makes graphene the key ingredient is the way it interacts with tungsten at the atomic level. In a conventional device, heat causes metal atoms to drift slowly through the ceramic layer until they bridge the two electrodes, short circuiting everything and leaving the device permanently broken. Graphene stops that process dead. Its surface chemistry with tungsten is ... almost like oil and water. Tungsten atoms that drift toward the graphene find they simply cannot take hold, no anchor, no short circuit, no failure. The team used advanced electron microscopy and quantum level computer simulations to understand exactly why, turning a single lucky result into a repeatable principle. The findings have been published in the journal Science.

The biotech industry's engineered cells could become an $8 trillion market by 2035, notes Phys.org. But how do you keep them from being stolen? Their article notes "an uptick in the theft and smuggling of high-value biological materials, including specially engineered cells." In Science Advances, a team of U.S. researchers present a new approach to genetically securing precious biological material. They created a genetic combination lock in which the locking or encryption process scrambled the DNA of a cell so that its important instructions were non-functional and couldn't be easily read or used. The unlocking, or decryption, process involves adding a series of chemicals in a precise order over time — like entering a password — to activate recombinases, which then unscramble the DNA to their original, functional form...

They created a biological keypad with nine distinct chemicals, each acting as a one-digit input. By using the same chemicals in pairs to form two-digit inputs, where two chemicals must be present simultaneously to activate a sensor, they expanded the keypad to 45 possible chemical inputs without introducing any new chemicals. They also added safety penalties — if someone tampers with the system, toxins are released — making it extremely unlikely for an unauthorized person to access the cells.
"The researchers conducted an ethical hacking exercise on the test lock and found that random guessing yielded a 0.2% success rate, remarkably close to the theoretical target of 0.1%."

"Breathable oxygen has been created from Moon dust," reports the Telegraph, "in a world first that paves the way for a lunar base."

Jeff Bezos's Blue Origin ""announced this week that it had developed a reactor that could successfully release oxygen from lunar soil by using an electric current." Almost half of Moon dust — the thin layer of rock that blankets the lunar surface — is oxygen, but it is bound to metals such as iron and titanium... Previous work to isolate oxygen has been lab-based, and the unwieldy equipment needed has been too difficult to send to the Moon. In contrast, Blue Origin said its small-scale reactor, named Air Pioneer, could be made flight-ready to "provide the first breath of life for a sustainable Moon base"... As well as breathable air, Blue Origin said the reactor produces other critical elements for planetary infrastructure, such as iron, aluminium and silicon for construction and electronics, as well as glass for windows and solar panel covers. The company has previously said it wants to turn the Moon, and eventually Mars, into "self-sustaining worlds where robots and humans can go beyond visiting and truly explore, grow, live, and thrive"....

Blue Origin said it would need to generate around one megawatt of power to drive the reactors — about the energy it would require to power around 400 to 1,000 homes simultaneously. It envisages that each lunar settlement would have an array of nearby solar panels, generating the power needed for one reactor.
Besides breathable air for astronauts, the oxygen could also be used in propellant for refuelling landers and fuel cells, Blue Origin points out — and "produced right where they're needed, and at much lower cost than being brought from Earth."

Thanks to Slashdot reader fjo3 for sharing the article.

Critics say social media is engineered to be as addictive as tobacco or gambling, writes the Washington Post — while adding that "the science has been moving in parallel with the court's recognition." A growing body of research links heavy social media use not only to declines in mental health but to measurable cognitive effects — on attention, memory and focus — that in some studies resemble accelerated aging. Science also suggests we have more control than we realize when it comes to reversing this damage, and the solution is surprisingly simple: Take a break... "Digital detoxes" can sound like a fad. But in one of the largest studies to date, published in PNAS Nexus and involving more than 467 participants with an average age of 32, even a short time away produced striking results — effectively erasing a decade of age-related cognitive decline.

For 14 days, participants used a commercially available app, Freedom, to block internet access on their phones. They were still allowed calls and text messages, essentially turning a smartphone into a dumb phone. Their time online decreased from 314 minutes to 161 minutes, and by the end of the period the participants had improvements in sustained attention, mental health as well as self-reported well-being. The improvement in sustained attention was about the same magnitude as 10 years of age-related decline, the researchers noted, and the effect of the intervention on depression symptoms was larger than antidepressants and similar to that of cognitive behavioral therapy.

But two things were even more mind-blowing... Even those people who cheated and broke the rules after a few days seemed to have positive effects from the break; and in follow-up reports after the two weeks, many people reported the positive effects lingered. "So you don't have to necessarily restrict yourself forever. Even taking a partial digital detox, even for a few days, seems to work," Kushlev said.
The article also notes a November study at Harvard published in JAMA Network Open where nearly 400 people 'found that even a short break can make a measurable difference: After just one week of reduced smartphone use, participants reported drops in anxiety (16.1 percent), depression (24.8 percent) and insomnia (14.5 percent)..."

"Other experiments point in the same direction — whether decreasing social media use by an hour a day for one week or stepping away from just Facebook and Instagram."

NASA's Artemis II crew safely splashed down off the California coast after completing a 10-day trip around the moon and back. "This is not just an accomplishment for NASA," sad NASA Administrator Jared Isaacman. "This is an accomplishment for humanity, again, a historic mission to the moon and back." From a report: Isaacman is aboard the USS John. P Murtha Navy recovery vessel, where the astronauts will be brought once they've been retrieved from the Orion capsule, and he shared "there is a lot to celebrate right now on on a mission well accomplished for Artemis II."

Isaacman also complimented the crew as "absolutely professional astronauts, wonderful communicators and almost poets" "" as well as "ambassadors from humanity to the stars." "I can't imagine a better crew than the Artemis II crew that just completed a perfect mission right now. We are back in the business of sending astronauts to the moon and bringing them back safely.

This is just the beginning. We are going to get back into doing this with frequency, sending missions to the moon until we land on it in 2028 and start building our base." Isaacman also said it's time to start preparing for Artemis III, expected to launch in 2027. You can watch the moment of the splashdown here.

Researchers say the world's largest known wild chimpanzee community in Uganda fractured into rival factions and has been locked in a vicious "civil war" for the last eight years. "It is not clear exactly why the once close-knit community of Ngogo chimpanzees at Uganda's Kibale National Park are at loggerheads, but since 2018 the scientists have recorded 24 killings, including 17 infants," reports the BBC. From the report: [O]ver several decades, [lead author Aaron Sandel] said the nearly 200 Ngogo chimpanzees had lived in harmony. There were divided into two sets - known to researchers as Western and Central - but they had existed overall as a cohesive group. Sandel said he first noticed them polarizing in June 2015, when the Western chimpanzees ran away and were chased by the Central group. "Chimpanzees are sort of melodramatic," he said, explaining that following arguments there would ordinarily be "screaming and chasing" and then later, they would grooming and co-operating.

But following the 2015 dispute, the researchers saw that there was a six-week avoidance period between the two sets, with interactions becoming more infrequent. When they did occur, Sandel said they were "a little more intense, a little more aggressive." Following the emergence of the two distinct groups in 2018, members of the Western group started attacking the Central chimpanzees. In 24 targeted attacks since the split, at least seven adult males and 17 infants from the Central chimps have been killed, the study found, although the researchers believe the actual number of deaths are higher. The researchers believe many factors such as the group size and subsequent competition of resources, and "male-male competition" for reproducing may be to blame.

But they say there were three likely catalysts:
- The first, were the deaths of five adult males and one adult female -- for reasons unknown -- in 2014, which could have disrupted social networks and weakened social ties across the subgroups
- The following year, there was a change in the alpha male, which the study says coincided with the first period of separation between the Western and Central groups. "Changes in the dominance hierarchy can increase aggression and avoidance in chimpanzees," it explained
- The third factor was the deaths of 25 chimpanzees, including four adult males and 10 adult females, as a result of a respiratory epidemic, in 2017, a year before the final separation. One of the adult males who died was "among the last individuals to connect the groups," the research paper said. The study has been published in the journal Science.

Longtime Slashdot reader fahrbot-bot shares a report from NewScientist: According to quantum chromodynamics (QCD) -- widely considered to be our best theory for describing the strong force, which binds quarks inside protons and neutrons -- even a perfect vacuum isn't truly empty. Instead, it is filled with short-lived disturbances in the underlying energy of space that flicker in and out of existence, known as virtual particles. Among them are quark-antiquark pairs. Under normal conditions, these fleeting pairs vanish almost as soon as they appear. But if enough energy is injected into a vacuum, QCD predicts they can be promoted into real, detectable particles with measurable mass. Now, the STAR collaboration -- an international team of physicists working at the Relativistic Heavy Ion Collider in Brookhaven National Laboratory in New York state -- has observed this process for the first time.

The team smashed together high-energy protons in a vacuum, producing a spray of particles. Some of these particles should be quark-antiquark pairs pulled directly from the vacuum itself, but quarks can never exist alone and immediately combine into composite particles. Quarks and antiquarks are born with their spins correlated -- a shared quantum alignment inherited from the vacuum. The researchers found that this link persists even after the quarks and antiquarks become part of larger particles called hyperons, which decay in less than a tenth of a billionth of a second. Spotting these spin-aligned hyperons in the aftermath of the proton collisions allowed the researchers to confirm that the quarks within them came from the vacuum. The findings have been published in the journal Nature.

Artemis II has broken the Apollo 13 record for the farthest distance humans have ever traveled from Earth. NASA reports: The Artemis II crew of NASA astronauts Reid Wiseman, Victor Glover, and Christina Koch, along with CSA (Canadian Space Agency) astronaut Jeremy Hansen have set the record for the farthest distance from Earth traveled by a human mission, surpassing the Apollo 13 record of 248,655 miles set in 1970.

NASA Flight Director Brandon Lloyd, Capsule Communicator Amy Dill, and Command and Handling Data Officer Brandon Borter also marked a lighthearted milestone today by emailing the crew what is now assumed to be the longest person-to-person message ever sent in human history. After breaking the record for human spaceflight, crew also took a moment to provisionally name a couple of craters on the Moon, noting they were able to see them with their naked eye.

Just northwest of Orientale basin highlighted above is a crater they would like to name Integrity after their spacecraft and this historic mission. Just northeast of Integrity, on the near and far side boundary, and sometimes visible from Earth, the crew suggested Carroll crater in honor of Reid Wiseman's late wife, Carroll Taylor Wiseman. After this mission is complete, the crater name proposals will be formally submitted to the International Astronomical Union, the organization that governs the naming of celestial bodies and their surface features. On April 1, NASA successfully launched humanity's first crewed trip around the Moon in more than 50 years. A couple of days into the mission, attention turned to a more mundane problem when reports said the astronauts had access to "two Microsoft Outlooks" and neither was working properly. By April 4, the crew had passed 100,000 miles from Earth as they continued deeper into space, and by April 6, they had entered the Moon's gravitational pull and caught their first views of the lunar far side.

NASA's Artemis astronauts are now entering "the lunar sphere of influence," reports NBC News, "meaning the pull of the moon's gravity will become stronger than Earth's." Now as they begin their swing around the moon, the Artemis astronauts "are chasing after Apollo 13's maximum range from Earth," reports the Associated Press, hoping to beat its distance from Earth by more than 4,100 miles (6,600 kilometers).

They'll begin their six-hour lunar flyby 14 hours from now (at 2:45 p.m. ET Monday). But in a space-to-earth interview Saturday with NBC News, the astronauts were already describing their first glimpses of the edge of the far side: [NASA astronaut Christina Koch realized] it looked different from what she was accustomed to on Earth. "The darker parts just aren't quite in the right place," she said. "And something about you senses that is not the moon that I'm used to seeing...."

[Astronaut Reid] Wiseman called the flight a "magnificent accomplishment" and said the astronauts' ability to gaze at both Earth and the moon from their spacecraft has been "truly awe-inspiring." "The Earth is almost in full eclipse. The moon is almost in full daylight, and the only way you could get that view is to be halfway between the two entities," he said... And while the early photos of Earth and the moon that [Canadian astronaut Jeremy] Hansen and his colleagues have beamed back have been spectacular, the Canadian astronaut said they pale in comparison to the real deal outside their capsule's windows. "I know those photos are amazing," he said, "but let me assure you, it is another level of amazing up here."
And their upcoming six-hour lunar flyby "promises views of the moon's far side that were too dark or too difficult to see by the 24 Apollo astronauts who preceded them," notes the Associated Press: A total solar eclipse also awaits them as the moon blocks the sun, exposing snippets of shimmering corona.... At closest approach, they will come within 4,070 miles (6,550 kilometers) of the moon. Because they launched on April 1, the rendezvous won't have as much of the far lunar side illuminated as other dates would have. But the crew still will be able make out "definite chunks of the far side that have never been seen" by humans, said NASA geologist Kelsey Young, including a good portion of Orientale Basin.

They'll call down their observations as they photograph the gray, pockmarked scenes. There's a suite of professional-quality cameras on board, and each astronaut also has an iPhone for more informal, spur-of-the-minute picture-taking... Orion will be out of contact with Mission Control for nearly an hour when it's behind the moon. The same thing happened during the Apollo moonshots. NASA is relying on its Deep Space Network to communicate with the crew, but the giant antennas in California, Spain and Australia won't have a direct line of sight when Orion disappears behind the moon for approximately 40 minutes...

Once Artemis II departs the lunar neighborhood, it will take four days to return home. The capsule will aim for a splashdown in the Pacific near San Diego on April 10, nine days after its Florida launch. During the flight back, the astronauts will link up via radio with the crew of the orbiting International Space Station. This is the first time that a moon crew has colleagues in space at the same time and NASA can't pass up the opportunity for a cosmic chitchat.

Plants, toads, and mushrooms "can all produce psychedelic substances," writes ScienceAlert.

"And now their powers have been combined in one plant." [S]cientists have taken the genes these organisms use to make five natural psychedelics and introduced them into a tobacco plant ( Nicotiana benthamiana), which then produced all five compounds simultaneously. As interest grows in psychedelics as potential treatments for illnesses such as depression, anxiety, and PTSD, the newly developed system could offer scientists a new way to produce these compounds for research purposes...

[P]rogress in this field remains limited, in part due to regulatory restrictions, underscoring the need for more research. This creates practical challenges for scientists. "Traditionally, the supply of psychedelics relies on natural producers, mainly plants, fungi, and the Sonoran Desert toad," the researchers write. "Harvesting these organisms for their psychoactive compounds raises ecological and ethical concerns, being increasingly threatened by habitat loss and overexploitation..."

[T]he team carefully monitored the plant's production of five psychedelic tryptamines: DMT originally from plants; psilocin and psilocybin from mushrooms; and bufotenin and 5-MeO-DMT from toads. The modified tobacco plants were found to produce all five compounds simultaneously.
The article points out that the researchers "also took it a step further." By tweaking the enzymes they were able to "produce modified versions of the compounds that do not naturally occur in plants, and which may also have therapeutic value."

An anonymous reader quotes a report from Ars Technica: When it comes to large language model-powered tools, there are generally two broad categories of users. On one side are those who treat AI as a powerful but sometimes faulty service that needs careful human oversight and review to detect reasoning or factual flaws in responses. On the other side are those who routinely outsource their critical thinking to what they see as an all-knowing machine. Recent research goes a long way to forming a new psychological framework for that second group, which regularly engages in "cognitive surrender" to AI's seemingly authoritative answers. That research also provides some experimental examination of when and why people are willing to outsource their critical thinking to AI, and how factors like time pressure and external incentives can affect that decision.

Overall, across 1,372 participants and over 9,500 individual trials, the researchers found subjects were willing to accept faulty AI reasoning a whopping 73.2 percent of the time, while only overruling it 19.7 percent of the time. The researchers say this "demonstrate[s] that people readily incorporate AI-generated outputs into their decision-making processes, often with minimal friction or skepticism." In general, "fluent, confident outputs [are treated] as epistemically authoritative, lowering the threshold for scrutiny and attenuating the meta-cognitive signals that would ordinarily route a response to deliberation," they write. These kinds of effects weren't uniform across all test subjects, though. Those who scored highly on separate measures of so-called fluid IQ were less likely to rely on the AI for help and were more likely to overrule a faulty AI when it was consulted. Those predisposed to see AI as authoritative in a survey, on the other hand, were much more likely to be led astray by faulty AI-provided answers.

Despite the results, though, the researchers point out that "cognitive surrender is not inherently irrational." While relying on an LLM that's wrong half the time (as in these experiments) has obvious downsides, a "statistically superior system" could plausibly give better-than-human results in domains such as "probabilistic settings, risk assessment, or extensive data," the researchers suggest. "As reliance increases, performance tracks AI quality," the researchers write, "rising when accurate and falling when faulty, illustrating the promises of superintelligence and exposing a structural vulnerability of cognitive surrender." In other words, letting an AI do your reasoning means your reasoning is only ever going to be as good as that AI system. As always, let the prompter beware.

The Artemis II crew has passed 100,000 miles from Earth and is now on a "free-return" path around the moon after a successful "translunar" injection burn. "Ladies and gentlemen, I am so, so excited to be able to tell you that for the first time since 1972 during Apollo 17, human beings have left Earth orbit," NASA's Dr Lori Glaze told a news conference. The Guardian reports: The astronauts -- the Americans Reid Wiseman, Victor Glover and Christina Koch, and a Canadian, Jeremy Hansen -- spent their first day in space performing checks on the spacecraft, which had never carried humans before. Later they had time to speak to US TV networks. "I've got to tell you, there is nothing normal about this," Wiseman told ABC News from the cramped interior of the capsule. "Sending four humans 250,000 miles away is a herculean effort, and we are now just realising the gravity of that."

Orion will travel about 4,000 miles (6,400km) beyond the moon before turning back, providing unprecedented and illuminated views of the lunar far side. If all proceeds smoothly, the astronauts will set a record by venturing farther from Earth than any human before -- more than 250,000 miles. The mission is part of a longer-term plan to repeatedly return to the moon, with the aim of establishing a permanent base that will offer a platform for further exploration. After the final engine burn, NASA said Wiseman took two "spectacular" images of Earth.

The first photo, called Hello, World, "shows the vast expanse of blue that is the Atlantic Ocean, framed by a thin glow of the atmosphere as the Earth eclipses the Sun and green auroras at either pole," reports the BBC. Another photo shows the view of Earth from inside the Orion spacecraft.

Longtime Slashdot reader fahrbot-bot writes: CU Boulder researchers are reporting that they have discovered an appetite-suppressing compound in python blood that helps the snakes consume enormous meals and go months without eating yet remain metabolically healthy. The findings were published in the journal Natural Metabolism on March 19, 2026.

Pythons can grow as big as a telephone pole, swallow an antelope whole, and go months or even years without eating -- all while maintaining a healthy heart and plenty of muscle mass. In the hours after they eat, research has shown, their heart expands 25% and their metabolism speeds up 4,000-fold to help them digest their meal. The team measured blood samples from ball pythons and Burmese pythons, fed once every 28 days, immediately after they ate a meal. In all, they found 208 metabolites that increased significantly after the pythons ate. One molecule, called para-tyramine-O-sulfate (pTOS) soared 1,000-fold.

Further studies, done with Baylor University researchers, showed that when they gave high doses of pTOS to obese or lean mice, it acted on the hypothalamus, the appetite center of the brain, prompting weight loss without causing gastrointestinal problems, muscle loss or declines in energy. The study found that pTOS, which is produced by the snake's gut bacteria, is not present in mice naturally. It is present in human urine at low levels and does increase somewhat after a meal. But because most research is done in mice or rats, pTOS has been overlooked. "We've basically discovered an appetite suppressant that works in mice without some of the side-effects that GLP-1 drugs have," said senior author Leslie Leinwand, a distinguished professor of Molecular, Cellular and Developmental Biology who has been studying pythons in her lab for two decades. Drugs like Ozempic and Wegovy act on the hormone glucagon-like petide-1 (GLP-1).

Even on NASA's Artemis II mission around the moon, astronauts apparently still have to deal with broken Microsoft Outlook. One of the crew members, Reid Wiseman, jokingly reported that he had "two Microsoft Outlooks" and neither worked. 404 Media reports: On April 1, four astronauts from the U.S. and Canada embarked on a 10-day flight to loop around the moon. Spotted by VGBees podcast host Niki Grayson on the NASA livestream of live views from the , around 2 a.m. ET, mission control acknowledges an issue with a process control system and offers to remote in -- yes, like how your office IT guy would pause his CoD campaign to log into Okta for you because you used the wrong password too many times.

One of the astronauts, Reid Wiseman, says that's chill, but while they're in there: "I also see that I have two Microsoft Outlooks, and neither one of those are working." Astronauts are trained for decades in some of the most physically and mentally grueling environments of any career. They're some of the smartest people on the planet, and they have to be, before we strap them to 3.2 million pounds of jet fuel and make them do complex experiments and high-stakes decisions for days on end. And yet, once they get up there, fucking Outlook is borked.

NASA's Artemis II mission has launched four astronauts around the moon and back, marking humanity's first crewed lunar voyage in 53 years and the first test flight of NASA's Orion capsule and Space Launch System (SLS) with people on board. Five minutes into the flight, Commander Reid Wiseman saw the team's target: "We have a beautiful moonrise, we're headed right at it," he said from the capsule. The Associated Press reports: Artemis II set sail from the same Florida launch site that sent Apollo's explorers to the moon so long ago. The handful still alive cheered this next generation's grand adventure as the Space Launch System rocket thundered into the early evening sky, a nearly full moon beckoning some 248,000 miles (400,000 kilometers) away.

Artemis II commander Reid Wiseman led the charge into space with "Let's go to the moon!" accompanied by pilot Victor Glover, Christina Koch and Canada's Jeremy Hansen. It was the most diverse lunar crew ever with the first woman, person of color and non-U.S. citizen riding in NASA's new Orion capsule.

Carrying three Americans and one Canadian, the 32-story rocket rose from NASA's Kennedy Space Center where tens of thousands gathered to witness the dawn of this new era. Crowds also jammed the surrounding roads and beaches, reminiscent of the Apollo moonshots in the 1960s and '70s. It is NASA's biggest step yet toward establishing a permanent lunar presence. Visit NASA's Artemis II Launch Day blog for the latest updates.

Developing...

MIT Technology Review discovered that startup R3 Bio has pitched an ethically and scientifically explosive long-term vision beyond its public work on non-sentient monkey "organ sacks": creating human "brainless clones" or replacement bodies for organs as part of an extreme life-extension agenda. From the report: Imagine it like this: a baby version of yourself with only enough of a brain structure to be alive in case you ever need a new kidney or liver. Or, alternatively, he has speculated, you might one day get your brain placed into a younger clone. That could be a way to gain a second lifespan through a still hypothetical procedure known as a body transplant.

The fuller context of R3's proposals, as well as activities of another stealth startup with related goals, have not previously been reported. They've been kept secret by a circle of extreme life-extension proponents who fear that their plans for immortality could be derailed by clickbait headlines and public backlash. And that's because the idea can sound like something straight from a creepy science fiction film. One person who heard R3's clone presentation, and spoke on the condition of anonymity, was left reeling by its implications and shaken by [R3 founder John Schloendorn's] enthusiastic delivery. The briefing, this person said, was like a "close encounter of the third kind" with "Dr. Strangelove." [...]

MIT Technology Review found no evidence that R3 has cloned anyone, or even any animal bigger than a rodent. What we did find were documents, additional meeting agendas, and other sources outlining a technical road map for what R3 called "body replacement cloning" in a 2023 letter to supporters. That road map involved improvements to the cloning process and genetic wiring diagrams for how to create animals without complete brains. A main purpose of the fundraising, investors say, was to support efforts to try these techniques in monkeys from a base in the Caribbean. That offered a path to a nearer-term business plan for more ethical medical experiments and toxicology testing -- if the company could develop what it now calls monkey "organ sacks." However, this work would clearly inform any possible human version.

Researchers at the University of Waterloo say a new "quadratic quantum gravity" framework could explain the universe's rapid early expansion without adding extra ingredients to Einstein's theory by hand. The idea is especially notable because it makes testable predictions, including a minimum level of primordial gravitational waves that future experiments may be able to detect. "Even though this model deals with incredibly high energies, it leads to clear predictions that today's experiments can actually look for," said Dr. Niayesh Afshordi, professor of physics and astronomy at the University of Waterloo and Perimeter Institute (PI). "That direct link between quantum gravity and real data is rare and exciting." Phys.org reports: The research team found that the Big Bang's rapid early expansion can emerge naturally from this simple, consistent theory of quantum gravity, without adding any extra ingredients. This early burst of expansion, often called inflation, is a central idea in modern cosmology because it explains why the universe looks the way it does today.

Their model also predicts a minimum amount of primordial gravitational waves, which are tiny ripples in spacetime geometry created in the first moments after the Big Bang. These signals may be detectable in upcoming experiments, offering a rare chance to test ideas about the universe's quantum origins.

[...] The team plans to refine their predictions for upcoming experiments to explore how their framework connects to particle physics and other puzzles about the early universe. Their long-term goal is to strengthen the bridge between quantum gravity and observational cosmology. The research has been published in the journal Physical Review Letters.

Researchers found that common nitrile and latex lab gloves can shed stearate particles that closely resemble microplastics, potentially "increasing the risk of false positives when studying microplastic pollution," reports ScienceDaily.

"We may be overestimating microplastics, but there should be none," said Anne McNeil, senior author of the study and U-M professor of chemistry, macromolecular science and engineering. "There's still a lot out there, and that's the problem." From the report: Researchers found that these gloves can unintentionally transfer particles onto lab tools used to analyze air, water, and other environmental samples. The contamination comes from stearates, which are not plastics but can closely resemble them during testing. Because of this, scientists may be detecting particles that are not true microplastics. To reduce this issue, U-M researchers Madeline Clough and Anne McNeil recommend using cleanroom gloves, which release far fewer particles.

Stearates are salt-based, soap-like substances added to disposable gloves to help them separate easily from molds during manufacturing. However, their chemical similarity to certain plastics makes them difficult to distinguish in lab analyses, increasing the risk of false positives when studying microplastic pollution. "For microplastics researchers who have these impacted datasets, there's still hope to recover them and find a true quantity of microplastics," said researcher and recent doctoral graduate Madeline Clough. "This field is very challenging to work in because there's plastic everywhere," McNeil said. "But that's why we need chemists and people who understand chemical structure to be working in this field."

The findings have been published in the journal Analytical Methods.

Project Hail Mary has now grossed $300.8 million globally after earning another $54.1 million this weekend from 86 markets, reports Variety, noting that after just nine days it's now Amazon MGM's highest-grossing film ever.

And last weekend it had the best opening for a "non-franchise" movie in three years, adds the Associated Press — the best since 2023's Oppenheimer: Project Hail Mary, which cost nearly $200 million to produce... is on an enviable trajectory. Its second weekend hold was even better than that of Oppenheimer, which collected $46.7 million in its follow-up frame.
But the movie is based on a book by The Martian author Andy Weir, described by one news outlet as "a former software engineer and self-proclaimed 'lifelong space nerd'... known for his realistic and clear-eyed approach to scientifically technical stories." Project Hail Mary has plenty of real science in it, whether it be space mathematics, physics, or astrobiology... The film's namesake project is even comprised of the space programs of other nations, such as Roscosmos from Russia, the Chinese space program, and the European Space Agency...

The story relies on work NASA has done regarding exoplanets, or planets outside our solar system... [This includes a nearby star named Tau Ceti approximately 12 light years from Earth which is orbited by four planets — two once thought to be in "the habitable zone" where liquid water can exist.] Tau Ceti has long been the setting used by sci-fi authors and storytellers. Isaac Asimov used it for his Robot series. Arthur C. Clarke's "Rama" spacecraft came across a mysterious tetrahedron in the Tau Ceti system. Authors Ursula K. Le Guin and Kim Stanley Robinson also set stories in Tau Ceti, and it also serves as the extrasolar setting of the 1968 Jane Fonda film Barbarella. Most recently, the Bungie video game Marathon is set in the far-off system, serving as part of the background story for the extraction shooter, about a large-scale plan to colonize the Tau Ceti system.
The movie also mentions 40 Eridani A, according to the article, a real star about 16 light-years away that was said to be orbited by the fictional planet Vulcan, home to Star Trek's Mr. Spock. It's also mentioned in Frank Herbert's Dune as the star system of the planets Ix and Richese ("noted for their machine culture and miniaturisation," according to the Stellar Australis site's "Project Dune" page).

And in a video on IMAX's YouTube channel, the film's directors explain how for a crucial scene they used non-visible-light photography, which is also an important part of modern astronomy. "Even the credits incorporate real astrophotography into the final moments," the article points out, using the work of award-winning Australian astrophotographer Rod Prazeres. "The only difference between his work of capturing space data in images and what ended up on the big screen was that he gave them 'starless versions' of his photographs to make it easier to place credit text over them."

Prazeres wrote on his web site that he was touched the producers "wanted the real thing... In a world where CGI and AI are everywhere, it meant a lot..."

How powerful is Jupiter's lightning? Thick clouds cover the view, notes Science magazine. But using an instrument on NASA's Juno spacecraft (orbiting Jupiter for the past decade), researchers determined Jupiter's lightning bolts are 100 to 10,000 times more energetic than earth's: A single bolt of lightning on Earth releases about 1 billion joules of energy. That means the most extreme bolts of jovian lightning carry 10 trillion joules of energy, equivalent to 2400 tons of TNT, or one-sixth the power of the atomic bomb dropped on Hiroshima, Japan. Based on the rates of flashes seen by Juno, storms on this tempestuous world can unleash the force of multiple nuclear weapons every minute...

The four storms Juno studied were monstrous, says Michael Wong, a planetary scientist at the University of California, Berkeley and one of the study's authors. There were three flashes per second on average, often emerging from the hearts of storms that are 3000 kilometers across, longer than the distance from New York City to Denver.
The researchers used the Hubble Space Telescope (and photographs from Juno's camera) to track Jupiter's storms with such precision that their radiometer could then pick out individual lightning flashes, according to the article. "It's just a massive ball of gas. It makes sense that there's very energetic lightning happening," says Daniel Mitchard, a lightning physicist at Cardiff University who wasn't involved with the new study. But confirming such suspicions "is exciting," he says, because lightning plays an important role in forging complex chemistry — including the sort that primordial life is built on.
Thanks to Slashdot reader sciencehabit for sharing the article.

In a new 4,000-word article, CNN tells the story of a retired appellate paralegal and grandmother in her early 70s who was treated for depression with psilocybin. CNN notes there's now retreats featuring psilocybin in a few countries — and while psilocybin is illegal under United States federal law, "In Oregon, 5,935 clients received psilocybin services through Oregon's state-regulated program in 2025." High doses of psilocybin are effective in treating depression, a growing body of research suggests, with promise for other conditions, like PTSD and addiction, said Dr. Albert Garcia-Romeu, associate director of the Center for Psychedelic and Consciousness Research at Johns Hopkins University... Some researchers suggest it disrupts entrenched traffic patterns in the brain or grows new neuron connections to change thinking. Others say the results from psilocybin could have to do with its anti-inflammatory effect, Garcia-Romeu said...

Colorado became the second state to make psilocybin legal with a 2023 law and issued its first healing center" last year. A law adopted in New Mexico last year established that state's Medical Psilocybin Program, now in development... Psilocybin seems to be "knocking on the door of FDA approval," said Dr. Lynn Marie Morski, president of the Psychedelic Medicine Association, which educates health care providers on the therapeutic use of psychedelics so they can answer patients' questions through the lenses of clinical evidence and harm reduction. Psilocybin therapy first received a "breakthrough therapy" designation for treatment-resistant depression from the US Food and Drug Administration in 2018, and now psilocybin drug products are on track to be submitted to the FDA for possible approval in the not-too-distant future.

While psilocybin is illegal under United States federal law, more states are creating their own paths for legal use under state laws.

After decades of studying, this week NASA announced "a major step forward in bringing nuclear power and propulsion from the lab to space." NASA will launch the Space Reactor-1 Freedom, the first nuclear powered interplanetary spacecraft, to Mars before the end of 2028, demonstrating advanced nuclear electric propulsion in deep space. Nuclear electric propulsion provides an extraordinary capability for efficient mass transport in deep space and enables high power missions beyond Jupiter where solar arrays are not effective.
Steven Sinacore, NASA's program executive for Fission Surface Power who will also oversee the SR-1 Freedom mission, emphasized to CNN that "On the ground the reactor is off. There's no radiation coming from it. It doesn't actually turn on until you're up in space, and that's where the radiation comes from." NASA says they aim to develop the capabilities required "for sustained exploration beyond the Moon and eventual journeys to Mars and the outer solar system."

And Space Reactor-1 Freedom will carry a fleet of tiny helicopters (much like Ingenuity) to explore Mars, reports Space.com: Whereas Ingenuity was a technology demonstrator, however, the Skyfall fleet will have concrete tasks. Chief among them is scout: If all goes to plan, the little choppers will help NASA assess the potential of their target area (wherever that happens to be) to support human exploration. The Skyfall helicopters will carry cameras and ground-penetrating radar to scout a future landing site, to understand the slopes and hazards for human-scale landers," Steve Sinacore, the program executive for NASA's Space Reactors Office, said during the briefing. "They will also map and characterize the subsurface water ice to find out where the water ice deposits are, along with the size, depth and other important characteristics," he added...

And that might not be the end of the line for SR-1 Freedom; NASA may decide to keep flying the spacecraft out into the solar system after it deploys the Skyfall choppers, according to Sinacore. The mission architecture, like much of NASA's exploration portfolio, is not yet finalized.

Long-time Slashdot reader Qbertino writes: ... but the CERN Project "Antimatter in motion" just did it. For the first time in history researchers at CERN have transported 92 antiprotons on a truck in a specially designed magnetic enclosure. The test-drive went so well that the researchers spontaneously decided to go another round... The purpose of the experiment was to test the feasibility of transporting antimatter to other facilities in Europe to conduct further antimatter research. German news Tagesschau has a nice report.
CNN reports that the antiproton enclosure was nearly six feet tall and weighed about 1,760 pounds. And Smithsonian magazine explains that it trapped the antiprotons in a vacuum chamber that had to be cooled to around -450 degrees Fahrenheit: Experts used a crane to carefully move the box of precious cargo from a lab onto a truck, which took about three hours, per the Associated Press' Jamey Keaten. Then, they drove the vehicle for roughly 30 minutes around CERN's campus, and subsequently returned the antiprotons to the lab. They worked with so little antimatter that even if it did touch ordinary matter and annihilate, it would release a small amount of energy detectable only by a special instrument, reports the AP.

UK startup Pulsar Fusion says it has achieved the first plasma ignition inside a nuclear fusion rocket engine prototype -- a huge step for space travel that could cut missions to Mars "from months-long journeys to just a few weeks," reports Euronews. From the report: Pulsar Fusion revealed the milestone during a live stream at Amazon's MARS Conference, hosted by Jeff Bezos in California this week, with CEO Richard Dinan calling it an "exceptional moment" for the company. The team successfully created plasma - an intensely hot, electrically charged state of matter, often described as the fourth state of matter - using electric and magnetic fields inside its experimental and early prototype "Sunbird fusion exhaust system." [...] The company now plans further testing of its Sunbird system to improve performance. Upcoming upgrades include more powerful superconducting magnets designed to better contain and control plasma.

CERN has confirmed it will host an expanded version of Open Research Europe, the EU-backed fee-free open access publishing platform that works to "keep knowledge in public hands." Research Professional News reports: A little over a year ago, 10 European research organizations announced that they would add their support to Open Research Europe, to broaden eligibility beyond only those researchers funded by the EU research program. Earlier this year, RPN reported that this group had expanded further and that Cern was set to host the broadened version of ORE, currently provided by the publisher F1000.

On March 26, Cern itself finally announced the news, saying it will "provide the technical and operational infrastructure" for the broader version. It said this will build on its "longstanding experience in developing and maintaining open science infrastructures and community-governed services." [...] In its own announcement, the Commission said ORE will have a budget of 17 million euros for 2026-31, with the EU providing 10 million euros.

Since it launched five years ago, ORE has published more than 1,200 articles. Cern said the platform is "expected to support a growing number of research outputs each year." Last month, experts told RPN they thought uptake of the increased eligibility will depend on how the newly participating national organizations engage with their communities. Eleven members of Science Europe, a group of major research funding and performing organizations, are part of the expansion.

An anonymous reader quotes a report from Physics World: Researchers at the CERN particle-physics lab have successfully transported antiprotons in a lorry across the lab's main site. The feat, the first of its kind, follows a similar test with protons in 2024. CERN says the achievement is "a huge leap" towards being able to transport antimatter between labs across Europe. [...] To do so, in 2020 the BASE team began developing a device, known as BASE-STEP (for Baryon-Antibaryon Symmetry Experiment-Symmetry Tests in Experiments with Portable Antiprotons), to store and transport antiprotons. It works by trapping particles in a Penning trap composed of gold-plated cylindrical electrode stacks made from oxygen-free copper that is surrounded by a superconducting magnet bore operated at cryogenic temperatures.

The device, which also contains a carbon-steel vacuum chamber to shield the particles from stray magnetic fields, is then mounted on an aluminium frame. This allows it to be transported using standard forklifts and cranes and withstand the bumps and vibrations of transport. In 2024, BASE researchers used the device to transport a cloud of about 105 trapped protons across CERN's Meyrin campus for four hours. After that feat, the researchers began to adjust BASE-STEP to handle antiprotons and yesterday the team successfully transported a trap containing a cloud of 92 antiprotons around the campus for 30 minutes, traveling up to 42 km/h.

With further improvements and tests, the team now hope to transport the antiprotons further afield. The first destination on the team's list is the Heinrich Heine University (HHU) in Dusseldorf, Germany, which would take about eight hours. "This means we'd have to keep the trap's superconducting magnet at a temperature below 8.2 K for that long," says BASE-STEP's leader Christian Smorra. "So, in addition to the liquid helium , we'd need to have a generator to power a cryocooler on the truck. We are currently investigating this possibility." If possible to transport to HHU, physicists would then use the particles to search for charge-parity-time violations in protons and antiprotons with a precision at least 100 times higher than currently possible at CERN.

alternative_right shares a report from Phys.org: Astronomers have an answer for a long-running mystery in astrophysics: why is the growth of supermassive black holes so much lower today than in the past? A study using NASA's Chandra X-ray Observatory and other X-ray telescopes found that supermassive black holes are unable to consume material as rapidly as they did in the distant past. The results appeared in the December 2025 issue of The Astrophysical Journal.

[...] The team ran tests of the three main possible scenarios currently being considered for the slowdown of black hole growth. These options were: could the decline in black hole growth be caused by less efficient rates of consumption, or by smaller typical black hole masses, or by fewer actively growing black holes? Their analysis of the data, extending over billions of years of cosmic history, led them to the conclusion that black holes are indeed consuming material less rapidly the later they are found after the Big Bang. The researchers expect this trend of slower-growing black holes to continue into the future.

NASA is reportedly halting work on the lunar Gateway in favor of a more direct push to build a lunar base. The new plan would cost tens of billions over the next decade, though the change could face hurdles because Congress previously funded Gateway specifically. SpaceNews reports: "Starting today, we're building humanity's first deep space outpost," said Carlos Garcia-Galan, program executive for NASA's moon base effort. The lunar base will take place in three phases. Phase 1, running from 2026 to 2028, "is all about getting to the moon reliably," he said. That includes a significant increase in the cadence of lander missions through the Commercial Lunar Payload Services and other programs. It will also focus on developing enabling technologies and getting "ground truth" for potential base locations at the lunar south pole.

Phase 2, from 2029 through 2031, starts building the base, he said. That would include building out communications, navigation, power and other infrastructure, developing larges CLPS cargo landers and supporting two crewed missions a year. Phase 3, beginning 2032, will enable "long distance and long duration human exploration" on the moon, he said, with routine logistics missions to the moon and uncrewed cargo return missions from the moon. Garcia-Galan said NASA foresees spending $10 billion each on Phases 1 and 2. Phase 3, lasting to at least 2036, would cost an additional $10 billion or more.

The base would leverage existing programs, although with some changes. NASA is planning to revamp the Lunar Terrain Vehicle program after concluding the current approach would take too long to get a crew-capable rover to the moon. "We were projecting a delivery on the lunar surface by 2030," he said. The agency is instead issuing a draft request for proposals for simplified rovers that could be quicker and easier to develop but could be upgraded later. The base, though, would include some new capabilities and technologies. One example Garcia-Galan provided was MoonFall, a drone that would be able to hop from one location to another on the lunar surface. The drones will be "built on the legacy" of Ingenuity, the small Mars helicopter. "We're going to take everything that we learned from Ingenuity's systems, the avionics, all of that, to build this."

Computershack shares a report from NBC News: Leonid Radvinsky, the owner of adult-content platform OnlyFans, has died of cancer at the age of 43, the company said in a statement on Monday. "We are deeply saddened to announce the death of Leo Radvinsky. Leo passed away peacefully after a long battle with cancer," an OnlyFans spokesperson said. "His family have requested privacy at this difficult time."


Radvinsky, a Ukrainian-American entrepreneur, acquired Fenix International Limited, the parent company of OnlyFans, in 2018 and served as its director and majority shareholder. He also runs Leo, a venture capital fund he founded in 2009 that focuses primarily on investments in technology companies. According to Reuters, OnlyFans is valued at around $5.5 billion, including debt.

"It is the talk of the town today — the loud boom, the flash of light in the sky experienced by a lot of folks across the Houston area this afternoon," says a local Texas newscaster. "And then there was this — a home in northwest Harris county hit by something that crashed through their roof."

Travelling at very high speed, the six-pound meteorite crashed through their roof and through their attic, crashing again through the ceiling of the floor below. It then bounced off the floor, hit the ceiling again — and then fell onto the bed.

CBS News reports: NASA said in a social media post that the meteor became visible at 49 miles above Stagecoach, northwest of Houston, at 4:40 p.m. local time. The meteor moved southeast at 35,000 miles per hour, breaking apart 29 miles above Bammel, just west of Cypress Station, NASA said. "The fragmentation of the meteor — which weighed about a ton with a diameter of 3 feet — created a pressure wave that caused booms heard by some in the area," NASA said in the post. Across the Houston area, residents described hearing a low, rumbling sound that many compared to thunder, even though the skies were clear, according to CBS affiliate KHOU.

Earlier this week, an asteroid weighing about 7 tons and traveling at 45,000 mph traveled over multiple states. And last June, a bright meteor was seen across the southeastern U.S. and exploded over Georgia, creating similar booms heard by residents in the area.

"Juicier steaks could soon be served up after barley was given the go-ahead to become Britain's first gene-edited crop," reports the Telegraph: In an effort to fatten up cows and get them to market faster, scientists have altered the DNA of Golden Promise barley to increase its fat content... [Regulators have approved the feeding of that barley to cows for further studies.] [T]he small increase reduces the time it takes for farmers to raise animals for slaughter and increases the amount of milk and meat they produce to make the industry more profitable.

The gene-edited barley is also able to cut the amount of methane a cow produces, [Rothamsted Research professor/biochemist Peter] Eastmond said... Reducing methane from cattle is a major goal of the industry, and Professor Eastmond estimated his barley could cut the methane output from a single cow by up to 15%.

The two genetic tweaks to the barley are believed to alter the gut bacteria in cows' stomachs and reduce the amount of methane-generating microbes, cutting the cows' emissions.... [Eastmond] is also working on applying the same two gene edits to rye grass to create pastures and meadows which are lipid-rich and calorie-dense. This, he said, could lead to entire fields of gene-edited grass which could be grazed by cows, sheep, horses and goats to fatten them up and cut emissions... "It would be better to have this technology in a pasture grass that's grown to supply the livestock and graze it directly."
The barley "has been modified to have a single letter of DNA removed from two different genes to switch them off," the article points out. "No genes have been added to its DNA and it is not considered to be genetically modified."

The article points out that Britain "has launched a push towards more gene-edited crops as a key post-Brexit freedom since splitting from the European Union," noting that U.K. scientists and private companies "have created products such as bread with fewer cancer-causing chemicals, longer-lasting strawberries and bananas, sweeter-tasting lettuce and disease-resistant potatoes, although these are yet to be granted permission to land on supermarket shelves..."

But the EU has so far resisted the sale of any gene-edited crops in the EU.

Thanks to long-time Slashdot reader fjo3 for sharing the article.

China's orbital outpost Tiangong was completed in 2022 and is hosting up to three astronauts at a time, reports CNN.

But meanwhile U.S. lawmakers are now signaling there's not time to develop and launch a replacement for the International Space Station — considered the signal most expensive object ever built — before its deorbiting in 2030. A recent Senate bill calls for the U.S. to continue funding it as late as 2032, but that bill still awaits approval from the U.S. Senate and the House.

But some private space companies are already building their alternatives: Private companies that are in the early design and mockup phase of developing these space stations are still waiting on NASA for guidance — and money... [NASA's "Requests for Proposals"] were delayed, in part because it took all of 2025 to cinch a confirmation for Trump's on-again-off-again pick for NASA administrator, Jared Isaacman [confirmed in December]... Similarly, 2025 saw a 45-day government shutdown, the longest in history — adding another hiccup in the space agency's plans to begin formally soliciting proposals from the private sector. Companies now expect that NASA will issue its Request for Proposals in late March or early April, one CEO told CNN...

Several commercial outfits have recently announced big funding influxes aimed at speeding up the development and launch of new orbiting outposts. Houston-based Axiom Space announced a $350 million funding round last month. Its California-based competitor Vast then notched a $500 million raise in early March. Vast is determined to launch a bare-bones station to orbit as soon as possible, with or without federal input, according to the company. "Our approach is to actually not wait for (NASA) and get going and build a minimum viable product, single-module space station called Haven-1, which we're launching into orbit next year," Vast CEO Max Haot told CNN in a phone interview earlier this month. Similarly, Axiom Space is working toward a 2028 launch date for a module that it plans to initially attach to the ISS before breaking off to orbit on its own. A spokesperson told CNN that it the company is "committed" to winning the NASA contract money and may continue pursing such goals even without contract awards.

Still, there's lingering doubt that any of the companies pursuing space stations will be able to stay afloat without securing a coveted NASA contract or at least cinching significant business from the public sector.
The article includes "Another complicating fact: Russia, the United States' primary partner on the ISS, has not pledged to keep operating its half of the space station past 2028." NASA will eventually evaluate proposals for an ISS alternative from Vast, Axiom Space, Jeff Bezos' Blue Origin, Max Space and several competitors including Voyager Technologies, CNN notes, ultimately handing out an estimated $1.5 billion in contracts between 2026 and 2031.

And while those companies may wait decades before a return on their investment, the article includes this quotes from the cofounder/general partner of Balerion Space Ventures, which led the fundraising for Vast. " What's obvious to us is you're going to have multiple vehicles with myriad companies go into space. You're going to have vehicles leaving from celestial bodies, like the moon. And we need a habitat."

NASA's Hubble Space Telescope unexpectedly captured a rare, early-stage breakup of comet C/2025 K1 (ATLAS) just days after it first began disintegrating. Phys.org reports: "Sometimes the best science happens by accident," said co-investigator John Noonan, a research professor in the Department of Physics at Auburn University in Alabama. "This comet got observed because our original comet was not viewable due to some new technical constraints after we won our proposal. We had to find a new target -- and right when we observed it, it happened to break apart, which is the slimmest of slim chances."

Noonan didn't know K1 was fragmenting until he viewed the images the day after Hubble took them. "While I was taking an initial look at the data, I saw that there were four comets in those images when we only proposed to look at one," said Noonan. "So we knew this was something really, really special." Hubble caught K1 fragmenting into at least four pieces, each with a distinct coma, the fuzzy envelope of gas and dust that surrounds a comet's icy nucleus. Hubble cleanly resolved the fragments, but to ground-based telescopes, at the time they only appeared as barely distinguishable, bright blobs. [...]

"Never before has Hubble caught a fragmenting comet this close to when it actually fell apart. Most of the time, it's a few weeks to a month later. And in this case, we were able to see it just days after," said Noonan. "This is telling us something very important about the physics of what's happening at the comet's surface. We may be seeing the timescale it takes to form a substantial dust layer that can then be ejected by the gas." The findings have been published in the journal Icarus.

sciencehabit shares a report from Science.org: In The Martian, fictional astronaut Mark Watney survives the wasteland of Mars by growing potatoes in lunar soil -- with a bit of help from human poop. The idea may not be so far-fetched. In a preprint posted this month on bioRxiv, researchers show potatoes can indeed grow in the equivalent of Moon dust, though they need a lot of help from compost found on Earth. To make the discovery, scientists first had to re-create lunar regolith -- the loose, powdery layer that blankets the Moon's surface. To replicate that in the lab, David Handy, a space biologist at Oregon State University (OSU), and his colleagues used a mix of crushed minerals and volcanic ash that matched the chemistry of the Moon.

But lunar regolith is entirely devoid of the organic matter that plants need to grow. "Turning an inorganic, inhospitable bucket of glorified sand into something that can support plant growth is complex," says Anna-Lisa Paul, a plant molecular biologist at the University of Florida not involved with the work. So Handy and his colleagues added vermicompost -- organic waste from worms -- into the regolith. They found that a mix with 5% compost allowed the potatoes to grow while still emulating the stressful conditions of the lunar environment. After almost 2 months of growth, the team harvested the tubers, freeze-dried them, and ground them up for further testing.

Analysis of the potatoes' DNA showed stress-related genes had been activated. The potatoes also had higher concentrations of copper and zinc than Earth-grown ones, which may make them dangerous for human consumption. The plants' nutritional value, though, was similar to traditional potatoes -- a surprise to the scientists, who expected lower levels of nutrition "because the plants might have been working overtime to overcome certain stressors," Handy says.

Nvidia unveiled its Vera Rubin Space-1 system for powering AI workloads in orbital data centers. "Space computing, the final frontier, has arrived," said CEO Jensen Huang. "As we deploy satellite constellations and explore deeper into space, intelligence must live wherever data is generated." CNBC reports: In a press release, the company said that its Vera Rubin Space-1 Module, which includes the IGX Thor and Jetson Orin, will be used on space missions led by multiple companies. The chips are specifically "engineered for size-, weight- and power-constrained environments." Partners include Axiom Space, Starcloud and Planet.

Huang said Nvidia is working with partners on a new computer for orbital data centers, but there are still engineering hurdles to overcome. "In space, there's no convection, there's just radiation," Huang said during his GTC keynote, "and so we have to figure out how to cool these systems out in space, but we've got lots of great engineers working on it."

Samples from the asteroid Ryugu contain all five nucleobases -- the key building blocks of DNA and RNA. "This strengthens the idea that asteroids may have brought the ingredients for the first living organisms to Earth long ago," reports New Scientist. From the report: Japan's Hayabusa 2 spacecraft visited Ryugu in 2018, where it shot two projectiles -- one small and one large -- into the surface of the asteroid and collected the resulting debris. It arrived back at Earth with the samples in 2020 and researchers have been analyzing these in detail ever since. Yasuhiro Oba at Hokkaido University in Japan and his colleagues examined two samples, one from the asteroid's surface and one comprised of subsurface materials excavated by the projectiles. In both, the team found all five primary nucleobases, which are the compounds that make up the nucleic acids DNA and RNA when combined with sugars and phosphoric acid.

This isn't the first time that nucleobases have been found in asteroid samples: they have been seen in meteorites, too, and in samples from the asteroid Bennu. The researchers did find different abundances of the various nucleobases among the various samples, though, which hints that these compounds might be useful for tracing asteroids and meteorites back to the parent bodies that they broke off from in the distant past, as well as understanding the evolution of those parent bodies over time. The findings have been published in the journal Nature Astronomy.

Last June Texas Agriculture Commissioner Sid Miller said in a statement that Texans "have a God-given right to know what's on their plate, and for millions of Texans, it better come from a pasture, not a lab. It's plain cowboy logic that we must safeguard our real, authentic meat industry from synthetic alternatives."

But California company Wildtype sells lab-grown salmon — and is suing Texas over its ban on cell-cultivated meat, the Austin Chronicle reported this week. The company's founder says lab-grown salmon eliminates the mercury, microplastic, and antibiotic contamination commonly found in seafood. And one chef in Austin, Texas says lab-grown salmon is "awesome" and "something new"-- at the only Texas restaurant that was serving it last summer: Just two months after the salmon hit the menu, Texas banned the sale of cell-cultivated meat... A lawsuit from Wildtype and one other FDA-approved cultivated meat company [argues] it's anti-capitalism and unconstitutional... This law "was not enacted to protect the health and safety of Texas consumers — indeed, it allows the continued distribution of cultivated meat to consumers so long as it is not sold. Instead, SB 261 was enacted to stifle the growth of the cultivated meat industry to protect Texas' conventional agricultural industry from innovative competition that is exclusively based outside of Texas...." [according to the lawsuit]. It was filed in September, immediately after the ban took effect, and cell-cultivated companies are awaiting judgment.
That Texas ban would last two years, notes U.S. News and World Reports, adding that Alabama, Florida, Indiana, Mississippi, Montana, and Nebraska have also passed bans, some temporary "on the manufacturing, sale or distribution of cell-cultured meat." Meanwhile, a new five-year moratorium on lab-grown meat was signed this week by the governor of South Dakota "after rejecting a permanent ban last month," reports South Dakota Searchlight: The new law bars the sale, manufacture or distribution of "cell-cultured protein" products from July 1 this year through June 30, 2031. Violations are punishable by up to 30 days in jail, a fine of up to $500, or both.
"But supporters of lab-grown meat are not going down without a fight," adds U.S. News and World Reports, with another lawsuit also filed challenging a ban in Florida: When Florida Gov. Ron DeSantis signed the ban in Florida, he described it as "fighting back against the global elite's plan to force the world to eat meat grown in a petri dish or bugs to achieve their authoritarian goals." He added that his administration "will save our beef."

BrianFagioli shares a report from NERDS.xyz: Cloud storage company Backblaze has partnered with StorageReview to make a massive dataset containing 314 trillion digits of Pi publicly accessible. The digits were calculated by StorageReview in December 2025 after months of heavy computation designed to stress modern hardware. The dataset now hosted in the cloud weighs in at over 130TB, while the full working dataset used during the calculation reached about 2.1PB when intermediate checkpoints were included. The report notes that the Pi digits have been broken into roughly 200GB chunks to make it more practical for researchers or enthusiasts to download.

Here's what StorageReview founder Brian Beeler said about the project: "Pushing [Pi] to 314 trillion digits was far more than a headline number. It was a sustained, months-long computational challenge that stressed every layer of modern infrastructure, from high core-count CPUs to massive high-speed storage, and it gave us valuable insight into how extreme, real-world workloads behave at scale. Making this dataset available in the Backblaze cloud takes the project a step further by opening access to one of the largest raw outputs ever generated in a single-system calculation. Hosting multi-petabyte files for the broader community is no small feat, and we appreciate Backblaze stepping up to ensure researchers, developers, and enthusiasts can explore and build on this record-setting achievement."

An anonymous reader quotes a report from the New York Times: In a paper, published last month in the journal The Anatomical Record, researchers offered a novel take on falling felines. Their evidence suggests new insights into the so-called falling cat problem, particularly that cats have a very flexible segment of their spines that allows them to correct their orientation midair. [...] People have been curious about falling cats perhaps as long as the animals have been living with humans, but the method to their acrobatic abilities remains enigmatic. Part of the difficulty is that the anatomy of the cat has not been studied in detail, explains Yasuo Higurashi, a physiologist at Yamaguchi University in Japan and lead author of the study. [...]

Modern research has split the falling cat problem into two competing models. The first, "legs in, legs out," suggests that cats correct their falling trajectory by first extending their hind limbs before retracting them, using a sequential twist of their upper and then lower trunk to gain the proper posture while in free fall. The second model, "tuck and turn," suggests that cats turn their upper and lower bodies in simultaneous juxtaposed movements. [...]

The researchers found that the feline spine was extremely flexible in the upper thoracic vertebrae, but stiffer and heavier in the lower lumbar vertebrae. The discovery matches video evidence showing the cats first turn their front legs, and then their lower legs. The results suggest the cat quickly spins its flexible upper torso to face the ground, allowing it to see so that it can correctly twist the rest of its body to match. "The thoracic spine of the cat can rotate like our neck," Dr. Higurashi said.

Experiments on the spine show the upper vertebrae can twist an astounding 360 degrees, he says, which helps cats make these correcting movements with ease. The results are consistent with the "legs in, legs out" model, but definitively determining which model is correct will take more work, Dr. Higurashi says. The results also yielded another discovery: Cats, like many animals, appear to have a right-side bias. One of the dropped cats corrected itself by turning to the right eight out of eight times, while the other turned right six out of eight times.

Van Allen Probe A, a 1,300-pound (600 kg) NASA satellite launched in 2012 to study Earth's radiation belts, is expected to re-enter Earth's atmosphere this week. While most of it is expected to burn up during descent, "some components may survive," reports the BBC. "The space agency said there is a one in 4,200 chance of being harmed by a piece of the probe, which it characterized as 'low' risk." From the report: The spacecraft is projected to re-enter around 19:45 EST (00:45 GMT) on Tuesday the U.S. Space Force predicted, according to Nasa, though there is a 24-hour margin of "uncertainty" in the timing. [...] The spacecraft and its twin, Van Allen Probe B, were on a mission to gather unprecedented data on Earth's two permanent radiation belts. It was not immediately clear where in Earth's atmosphere the satellite is projected to re-enter. NASA and the U.S. Space Force has said it will monitor the re-entry and update any predictions. [...] Van Allen Probe B is not expected to re-enter the Earth's atmosphere before 2030.

Since 1999, Slashdot has been covering the annual Ig Nobel prize ceremonies -- which honor real scientific research into strange or surprising subjects. "After 35 years in Boston, the annual prize ceremony will take place in Zurich, Switzerland, this year and will continue to be held in a European city for the foreseeable future," reports Ars Technica. "The reason: concerns about the safety of international travelers, who are increasingly reluctant to travel to the U.S. to participate."

"During the past year, it has become unsafe for our guests to visit the country," Marc Abrahams, master of ceremonies and editor of The Annals of Improbable Research magazine, told The Associated Press. "We cannot in good conscience ask the new winners, or the international journalists who cover the event, to travel to the U.S. this year." It comes on the heels of our recent story that many international game developers are opting to skip this year's weeklong Game Developers Conference in San Francisco, citing similar concerns. Ars Technica reports: Established in 1991, the Ig Nobels are a good-natured parody of the Nobel Prizes; they honor "achievements that first make people laugh and then make them think." As the motto implies, the research being honored might seem ridiculous at first glance, but that doesn't mean it's devoid of scientific merit. The unapologetically campy awards ceremony features miniature operas, scientific demos, and the 24/7 lectures, in which experts must explain their work twice: once in 24 seconds and again in just seven words.

Traditionally, the awards ceremony and related Ig Nobel events have taken place in Boston at Harvard University, Massachusetts Institute of Technology, and Boston University. However, four of last year's 10 winners opted to skip the ceremony rather than travel to the U.S., and the situation has not improved. [...] [T]his year, the Ig Nobel organizers are joining forces with the ETH Domain and the University of Zurich for hosting duties. "Switzerland has nurtured many unexpected good things -- Albert Einstein's physics, the world economy, and the cuckoo clock leap to mind -- and is again helping the world appreciate improbable people and ideas," Abraham said.

The Ig Nobels will not be returning to the U.S. any time soon. Instead, the plan is for Zurich to host every second year; every odd-numbered year, the ceremony will be hosted by a different European city. Abraham likened the arrangement to the Eurovision Song Contest.

A startup called Reflect Orbital wants to launch thousands of mirror-bearing satellites to reflect sunlight onto Earth at night and "power solar farms after sunset, provide lighting for rescue workers and illuminate city streets, among other things," reports the New York Times. From the report: It is an idea seemingly out of a sci-fi movie, but the company, Reflect Orbital of Hawthorne, Calif., could soon receive permission to launch its first prototype satellite with a 60-foot-wide mirror. The company has applied to the Federal Communications Commission, which issues the licenses needed to deploy satellites. If the F.C.C. approves, the test satellite could get a ride into orbit as soon as this summer. The F.C.C.'s public comment period on the application closes on Monday. "We're trying to build something that could replace fossil fuels and really power everything," Ben Nowack, Reflect Orbital's chief executive, said in an interview. The company has raised more than $28 million from investors.

[...] Reflect Orbital's first prototype, which will be roughly the size of a dorm fridge, is almost complete. Once in space, about 400 miles up, the test satellite would unfurl a square mirror nearly 60 feet wide. That would bounce sunlight to illuminate a circular patch about three miles wide on the Earth's surface. Someone looking up would see a dot in the sky about as bright as a full moon. Two more prototypes could follow within a year. By the end of 2028, Reflect Orbital hopes to launch 1,000 larger satellites, and 5,000 of them by 2030. The largest mirrors are planned to be nearly 180 feet wide, reflecting as much light as 100 full moons. The company said its goal was to deploy the full constellation of 50,000 satellites by 2035.

How much does it cost to order sunlight at night? Mr. Nowack said the company would charge about $5,000 an hour for the light of one mirror if a customer signed an annual contract for 1,000 hours or more. Lighting for one-time events and emergencies, which might require numerous satellites and more effort to coordinate, would be more expensive. For solar farms, he envisions splitting revenue from the electricity generated by the additional hours of light.

After decades of searching for extraterrestrial intelligence, the nonprofit SETI Foundation has an announcement. "A new study by researchers at the SETI Institute suggests stellar 'space weather' could make radio signals from extraterrestrial intelligence harder to detect." Stellar activity and plasma turbulence near a transmitting planet can broaden an otherwise ultra-narrow signal, spreading its power across more frequencies and making it more difficult to detect in traditional narrowband searches. For decades, many SETI experiments have focused on identifying spikes in frequency — signals unlikely to be produced by natural astrophysical processes. But the new research highlights an overlooked complication: even if an extraterrestrial transmitter produces a perfectly narrow signal, it may not remain narrow by the time it leaves its home system... "If a signal gets broadened by its own star's environment, it can slip below our detection thresholds, even if it's there, potentially helping explain some of the radio silence we've seen in technosignature searches," said Dr. Vishal Gajjar, Astronomer at the SETI Institute and lead author of the paper.
The researchers created "a practical framework for estimating how much broadening could occur for different types of stars" — and accounting for space weather — by "using radio transmissions from spacecraft in our own solar system, then extrapolated to other stellar environments."

The study's co-author (a SETI Institute research assistant) suggests this coud lead to better-targetted SETI searches. (M-dwarf stars — about 75% of stars in the Milky Way — actually have the highest likelihood that narrowband signals would get broadened before leaving their system...)

Colliding black holes were detected through spacetime ripples for the first time in 2015 by the Laser Interferometer Gravitational-Wave Observatory (LIGO), notes Space.com: Since then, LIGO and its partner gravitational wave detectors Virgo in Italy and KAGRA (Kamioka Gravitational Wave Detector) in Japan have detected a multitude of gravitational waves from colliding black holes, merging neutron stars, and even the odd "mixed merger" between a black hole and a neutron star... During the first three observing runs of LIGO, Virgo and KAGRA, scientists had only "heard" 90 potential gravitational wave sources.
But now they've published new data from the LIGO-Virgo-KAGRA (LVK) Collaboration that includes 128 more gravitatational wave sources — some incredibly distant: [Gravitational-Wave Transient Catalog-4.0, or GWTC-4] was collected during the fourth observational run of these gravitational wave detectors, which was conducted between May 2023 and Jan. 2024... Excitingly, GWTC-4 could technically have been even larger, as around 170 other gravitational wave detections made by LIGO, Virgo and KAGRA haven't yet made their way into the catalog.

One aspect of GWTC-4 that really stands out is the variety of events that created these signals. Within this catalog are gravitational waves from mergers between the heaviest black hole binaries yet, each about 130 times as massive as the sun, lopsided mergers between black holes with seriously mismatched masses, and black holes that are spinning at incredible speeds of around 40% the speed of light. In these cases, scientists think the extreme characteristics of the black holes involved in these mergers are the result of prior collisions, providing evidence of merger chains that explain how some black holes grow to masses billions of times that of the sun... GWTC-4 also includes two new mixed mergers involving black holes and neutron stars.

[LVK member Daniel Williams, of the University of Glasgow in the U.K., said in their statement] "We are really pushing the edges, and are seeing things that are more massive, spinning faster, and are more astrophysically interesting and unusual." The catalog also demonstrates just how sensitive the LVK detectors have become. Some of the neutron star mergers occurred up to 1 billion light-years away, while some of the black hole mergers occurred up to 10 billion light-years away.
Einstein's theory of general relativity can be tested with these detections, and "So far, the theory is passing all our tests," says LVK member Aaron Zimmerman, of the University of Texas at Austin. "But we're also learning that we have to make even more accurate predictions to keep up with all the data the universe is giving us." And LVK member Rachel Gray, a lecturer at the University of Glasgow, says "every merging black hole gives us a measurement of the Hubble constant, and by combining all of the gravitational wave sources together, we can vastly improve how accurate this measurement is."

In short, says LVK member Lucy Thomas of the California Institute of Technology (Caltech), "Each new gravitational-wave detection allows us to unlock another piece of the universe's puzzle in ways we couldn't just a decade ago."