Long-time Slashdot reader fjo3 shares an announcement from the U.S.-based nonprofit Consumer Reports: Protein powders still carry troubling levels of toxic heavy metals, according to a new Consumer Reports (CR) investigation. Our latest tests of 23 protein powders and ready-to-drink shakes from popular brands found that heavy metal contamination has become even more common among protein products, raising concerns that the risks are growing right alongside the industry itself. For more than two-thirds of the products we analyzed, a single serving contained more lead than CR's food safety experts say is safe to consume in a day — some by more than 10 times...

[I]n addition to the average level of lead being higher than what we found 15 years ago, there were also fewer products with undetectable amounts of it. The outliers also packed a heavier punch. Naked Nutrition's Vegan Mass Gainer powder, the product with the highest lead levels, had nearly twice as much lead per serving as the worst product we analyzed in 2010. Nearly all the plant-based products CR tested had elevated lead levels, but some were particularly concerning. Two had so much lead that CR's experts caution against using them at all... Dairy-based protein powders and shakes generally had the lowest amounts of lead, but half of the products we tested still had high enough levels of contamination that CR's experts advise against daily use...

Unlike prescription and over-the-counter drugs, the Food and Drug Administration doesn't review, approve, or test supplements like protein powders before they are sold. Federal regulations also don't generally require supplement makers to prove their products are safe, and there are no federal limits for the amount of heavy metals they can contain.
The article acknowledges that "Many of these powders are fine to have occasionally, and even those with the highest lead levels are far below the concentration needed to cause immediate harm. That said, because most people don't actually need protein supplements — nutrition experts say the average American already gets plenty — it makes sense to ask whether these products are worth the added exposure."

It's the world's largest network of environmental groups, according to NBC News, with more than 1,400 members from roughly 160 countries. It meets once every four years.

And in a vote Tuesday, the International Union for Conservation of Nature "approved further exploration of the use of genetic engineering tools to aid in the preservation of animal species and other living organisms." Researchers are already pursuing projects that involve changing some species' DNA. Scientists are genetically modifying mosquitoes to reduce transmission of diseases like malaria, for example, and synthesizing horseshoe crab blood, which is used in drug development. Controversial efforts to "de-extinct" archaic creatures — such as the so-called "dire wolf" that a biosciences company announced it had revived this spring — fall under the umbrella, as well. So do possibilities like modifying organisms to help them adapt to a warming world, which are on the table but further off in development.... The decision is applicable to work on a range of organisms, including animals, plants, yeasts and bacteria....

The notion of introducing genetic engineering into wild ecosystems would have been considered a nonstarter in most conservation circles a decade ago, according to Jessica Owley [a professor and environment law program director at the University of Miami]. But the intensifying effects of climate change and other stressors to biodiversity are bolstering arguments in favor of human intervention that could make endangered species resistant to those threats... The IUCN vote, she added, reflects a feeling of desperation among conservationists and governments, as existing regulations and conservation efforts fall short and species continue to disappear worldwide.
"A separate measure, a proposed moratorium on releasing genetically modified organisms into the environment, failed by a single vote..."

The James Webb Space Telescope gets its highest resolution with the aperture masking interferometer (or AMI), "a tiny piece of precisely machined metal that slots into one of the telescope's cameras," according to a new article by Benjamin Pope, an associated math professor at Macquarie University.

"We can finally present its first successful observations of stars, planets, moons and even black hole jets." [AMI] was put on Webb to diagnose and measure any blur in its images. Even nanometres of distortion in Webb's 18 hexagonal primary mirrors and many internal surfaces will blur the images enough to hinder the study of planets or black holes, where sensitivity and resolution are key. AMI filters the light with a carefully structured pattern of holes in a simple metal plate, to make it much easier to tell if there are any optical misalignments. We wanted to use this mode to observe the birth places of planets, as well as material being sucked into black holes. But before any of this, AMI showed Webb wasn't working entirely as hoped.

At very fine resolution — at the level of individual pixels — all the images were slightly blurry due to an electronic effect: brighter pixels leaking into their darker neighbours. This is not a mistake or flaw, but a fundamental feature of infrared cameras that turned out to be unexpectedly serious for Webb. This was a dealbreaker for seeing distant planets many thousands of times fainter than their stars a few pixels away: my colleagues quickly showed that its limits were more than ten times worse than hoped. So, we set out to correct it...

We built a computer model to simulate AMI's optical physics, with flexibility about the shapes of the mirrors and apertures and about the colours of the stars. We connected this to a machine learning model to represent the electronics with an "effective detector model" — where we only care about how well it can reproduce the data, not about why. After training and validation on some test stars, this setup allowed us to calculate and undo the blur in other data, restoring AMI to full function. It doesn't change what Webb does in space, but rather corrects the data during processing. It worked beautifully — the star HD 206893 hosts a faint planet and the reddest-known brown dwarf (an object between a star and a planet). They were known but out of reach with Webb before applying this correction. Now, both little dots popped out clearly in our new maps of the system... With the new correction, we brought Jupiter's moon Io into focus, clearly tracking its volcanoes as it rotates over an hour-long timelapse.
"This correction has opened the door to using AMI to prospect for unknown planets at previously impossible resolutions and sensitivities..." the article points out.

"Our results on painstakingly testing and enhancing AMI are now released on the open-access archive arXiv in a pair of papers."

Thanks to long-time Slashdot reader schwit1 for sharing the article.

Physicists using SLAC's X-ray free-electron laser discovered two new laser phenomena that allowed them to generate the shortest, highest-energy X-ray pulses ever recorded (60-100 attoseconds). These breakthroughs could let scientists observe electron motion and chemical bond formation in real time. Physicists Uwe Bergmann and Thomas Linker write in an article for The Conversation: In this new study we used X-rays, which have 100 million times shorter wavelengths than microwaves and 100 million times more energy. This meant the resulting new X-ray laser pulses were split into different X-ray wavelengths corresponding to Rabi frequencies in the extreme ultraviolet region. Ultraviolet light has a frequency 100 million times higher than radio waves. This Rabi cycling effect allowed us to generate the shortest high-energy X-ray pulses to date, clocking in at 60-100 attoseconds.

While the pulses that X-ray free-electron lasers currently generate allow researchers to observe atomic bonds forming, rearranging and breaking, they are not fast enough to look inside the electron cloud that generates such bonds. Using these new attosecond X-ray laser pulses could allow scientists to study the fastest processes in materials at the atomic-length scale and to discern different elements.

In the future, we also hope to use much shorter X-ray free-electron laser pulses to better generate these attosecond X-ray pulses. We are even hoping to generate pulses below 60 attoseconds by using heavier materials with shorter lifespans, such as tungsten or hafnium. These new X-ray pulses are fast enough to eventually enable scientists to answer questions such as how exactly an electron cloud moves around and what a chemical bond actually is. The findings have been published in the journal Nature.

fahrbot-bot shares a report from Popular Mechanics: [I]n a new study published in the journal Nature Materials, scientists from the Korea Research Institute of Standards and Science (KRISS) have now found yet another phase, appropriately named Ice XXI. At the heart of the experiment, scientists used diamond anvil cells (DACs) -- a common device used in materials science for squeezing samples under immense pressure -- to subject water to 2 gigapascals (20,000 times higher than normal atmosphere) of pressure in just 10 milliseconds.

The scientists call this kind of water "supercompressed," and it's metastable, meaning it persists for a time even when another form of ice would be more stable. And because of the immense pressure, ice forms at room temperature but the molecules are much more densely packed. "Rapid compression of water allows it to remain liquid up to higher pressures, where it should have already crystallized to ice VI," Geun Woo Lee, a co-author of the study from RISS, said in a press statement. "The structure in which liquid H2O crystallizes depends on the degree of supercompression of the liquid."

Scientists from Spain and China have successfully repaired the blood-brain barrier in Alzheimer's-model mice, enabling the brain to naturally clear amyloid-beta plaques and reverse cognitive decline. "After just three drug injections, mice with certain genes that mimic Alzheimer's showed a reversal of several key pathological features," adds ScienceAlert. From the report: Within hours of the first injection, the animal brains showed a nearly 45 percent reduction in clumps of amyloid-beta plaques, a hallmark of Alzheimer's disease. The mice had previously shown signs of cognitive decline, but after all three doses, the animals performed on par with their healthy peers in spatial learning and memory tasks. The benefits lasted at least six months.

These preclinical results don't guarantee success in humans, but they're an encouraging start, which the authors say "heralds a new era" in drug research. "The therapeutic implications are profound," claim the international team of researchers, co-led by scientists at the Institute for Bioengineering of Catalonia (IBEC) and the West China Hospital Sichuan University (WCHSU). The findings have been published in Signal Transduction and Targeted Therapy.

An anonymous reader quotes a report from the Conversation: Sound waves at frequencies above the threshold for human hearing are routinely used in medical care. Also known as ultrasound, these sound waves can help clinicians diagnose and monitor disease, and can also provide first glimpses of your newest family members. And now, patients with conditions ranging from cancer to neurodegenerative diseases like Alzheimer's may soon benefit from recent advances in this technology.

I am a biomedical engineer who studies how focused ultrasound -- the concentration of sound energy into a specific volume -- can be fine-tuned to treat various conditions. Over the past few years, this technology has seen significant growth and use in the clinic. And researchers continue to discover new ways to use focused ultrasound to treat disease. [...] Research on focused ultrasound has primarily focused on the most devastating and prevalent diseases, such as cancer and Alzheimer's disease. However, I believe that further developments in, and increased use of, focused ultrasound in the clinic will eventually benefit patients with rare diseases.

One rare disease of particular interest for my lab is cerebral cavernous malformation, or CCM. CCMs are lesions in the brain that occur when the cells that make up blood vessels undergo uncontrolled growth. While uncommon, when these lesions grow and hemorrhage, they can cause debilitating neurological symptoms. The most common treatment for CCM is surgical removal of the brain lesions; however, some CCMs are located in brain areas that are difficult to access, creating a risk of side effects. Radiation is another treatment option, but it, too, can lead to serious adverse effects.

We found that using focused ultrasound to open the blood-brain barrier can improve drug delivery to CCMs. Additionally, we also observed that focused ultrasound treatment itself could stop CCMs from growing in mice, even without administering a drug. While we don't yet understand how focused ultrasound is stabilizing CCMs, abundant research on the safety of using this technique in patients treated for other conditions has allowed neurosurgeons to begin designing clinical trials testing the use of this technique on people with CCM. With further research and advancements, I am hopeful that focused ultrasound can become a viable treatment option for many devastating rare diseases.

Math teachers across American schools are contending with a classroom disruption that has proven impossible to contain. The numbers six and seven now trigger instant pandemonium among students. They scream the phrase and perform a palms-up seesaw hand gesture whenever the numbers appear in equations or instructions.

Teachers have begun avoiding breaking students into groups of six or seven or asking them to turn to page 67. The meme has no meaning, reports WSJ. That absence of meaning is the point. The phenomenon traces back to late last year when Philadelphia rapper Skrilla released "Doot Doot (6 7)," a song referencing 67th street where his friends grew up. The phrase spiraled into youth culture in March through a viral video of a boy with forward-swept hair lurching toward a camera to deliver an animated "six seven." Skrilla is now touring venues where audiences wait for the six-seven line. Some teachers have attempted to neutralize the meme by saying it themselves.

A new study shows that common baker's yeast (Saccharomyces cerevisiae) can survive Mars-like conditions, including meteorite shock waves and toxic perchlorate salts found in Martian soil. Phys.org reports: Published in PNAS Nexus, Purusharth I. Rajyaguru and colleagues subjected Saccharomyces cerevisiae, which is a widely used model yeast, to shock waves and perchlorates. The authors chose the yeast in part because it has already been studied in space. When stressed, yeast, humans, and many other organisms form ribonucleoprotein (RNP) condensates, structures made of RNA and proteins that protect RNA and affect the fates of mRNAs. When the stressor passes, the RNP condensates, which include subtypes known as stress granules and P-bodies, disassemble.

The authors simulated Martian shock waves at the High-Intensity Shock Tube for Astrochemistry (HISTA) housed in the Physical Research Laboratory in Ahmedabad, India. Yeast exposed to 5.6 Mach intensity shock waves survived with slowed growth, as did yeast subjected to 100 mM sodium salt of perchlorate (NaClO4) -- a concentration similar to that in Martian soils. Yeast cells also survived exposure to the combined stress of shock waves and perchlorate stress. In both cases, the yeast assembled RNP condensates. Shock waves induced the assembly of stress granules and P-bodies; perchlorate caused yeast to make P-bodies but not stress granules. Mutants incapable of assembling RNP condensates were poor at surviving the Martian stress condition. Transcriptome analysis identified specific RNA transcripts perturbed by Mars-like conditions.

Researchers at UC San Diego and the University of Maryland have found that roughly half of geostationary satellite signals transmit sensitive data without encryption. The team spent three years using an $800 satellite receiver on a university rooftop in San Diego to intercept communications from satellites visible from their location. They collected phone calls and text messages from more than 2,700 T-Mobile users in just nine hours of recording.

The researchers also obtained data from airline passengers using in-flight Wi-Fi, communications from electric utilities and offshore oil and gas platforms, and US and Mexican military communications that revealed personnel locations and equipment details. The exposed data resulted from telecommunications companies using satellites to relay signals from remote cell towers to their core networks.

The researchers examined only about 15% of global satellite transponder communications and presented their findings at an Association for Computing Machinery conference in Taiwan this week. Most companies warned by the researchers have encrypted their satellite transmissions, but some US critical infrastructure owners have not yet added encryption.

NASA's Jet Propulsion Laboratory is laying off around 550 employees, or roughly 11% of its workforce, as part of an effort to "restructure and establish an appropriate size to ensure future success." According to JPL Director Dave Gallagher, the job cuts "are not related to the current government shutdown." CNBC reports: JPL is a research and development lab funded by NASA -- the federal space agency -- and managed by the California Institute of Technology. "While not easy, I believe that taking these actions now will help the Lab transform at the scale and pace necessary to help achieve humanity's boldest ambitions in space," Gallagher wrote in a separate mekor to JPL employees and contractors. Gallagher, in the public announcement, noted that the reorganization of JPL began in July, and "over the past few months, we have communicated openly with employees about the challenges and hard choices ahead."

"This week's action, while not easy, is essential to securing JPL's future by creating a leaner infrastructure, focusing on our core technical capabilities, maintaining fiscal discipline, and positioning us to compete in the evolving space ecosystem -- all while continuing to deliver on our vital work for NASA and the nation," Gallagher wrote. Gallagher said that JPL employees will be notified of their status on Tuesday, and the "new Lab structure ... will become effective Wednesday."

SpaceX's Starship megarocket successfully completed its 11th test flight, achieving major milestones like engine relight, satellite deployment, and a controlled splashdown in the Indian Ocean. From a report: This mission marks the second clean test run for Version 2, following a successful showing during its last test mission in August. Earlier this year, however, Starship Version 2 suffered three in-flight failures and an explosive accident during ground testing. Today's test mission is expected to be the last for the current iteration of Starship prototypes. The company has said it will debut a scaled up Version 3 for the next flight. You can watch a recording of the launch on YouTube.

ScienceDaily reports: Our everyday GPS struggles in "urban canyons," where skyscrapers bounce satellite signals, confusing even advanced navigation systems. Norwegian University of Science and Technology (NTNU) scientists created SmartNav, combining satellite corrections, wave analysis, and Google's 3D building data for remarkable precision. Their method achieved accuracy within 10 centimeters during testing [90% of the time]. The breakthrough could make reliable urban navigation accessible and affordable worldwide...

"Cities are brutal for satellite navigation," explained Ardeshir Mohamadi. Mohamadi, a doctoral fellow at NTNU, is researching how to make affordable GPS receivers (like those found in smartphones and fitness watches) much more precise without depending on expensive external correction services.

Off the southwest cost of Italy, a remotely operated submarine made "a significant and rare discovery," reports the Independent — a vast white coral reef that was 80 metres tall (262 feet) and 2 metres wide (6.56 feet) "containing important species and fossil traces." Often dubbed the "rainforests of the sea", coral reefs are of immense scientific interest due to their status as some of the planet's richest marine ecosystems, harbouring millions of species. They play a crucial role in sustaining marine life but are currently under considerable threat...

hese impressive formations are composed of deep-water hard corals, commonly referred to as "white corals" because of their lack of colour, specifically identified as Lophelia pertusa and Madrepora oculata species. The reef also contains black corals, solitary corals, sponges, and other ecologically important species, as well as fossil traces of oysters and ancient corals, the Italian Research Council said. It called them "true geological testimonies of a distant past."

Mission leader Giorgio Castellan said the finding was "exceptional for Italian seas: bioconstructions of this kind, and of such magnitude, had never been observed in the Dohrn Canyon, and are rarely seen elsewhere in our Mediterranean". The discovery will help scientists understand the ecological role of deep coral habitats and their distribution, especially in the context of conservation and restoration efforts, he added.
The undersea research was funded by the EU.

Thanks to davidone (Slashdot reader #12,252) for sharing the article.

fjo3 shares a report from the Washington Post: Across vast stretches of farmland in southern Brazil, researchers at a carbon removal company are attempting to accelerate a natural process that normally unfolds over thousands or millions of years. The company, Terradot, is spreading tons of volcanic rock crushed into a fine dust over land where soybeans, sugar cane and other crops are grown. As rain percolates through the soil, chemical reactions pull carbon from the air and convert it into bicarbonate ions that eventually wash into the ocean, where the carbon remains stored. The technique, known as "enhanced rock weathering," is emerging as a promising approach to lock away carbon on a massive scale. Some researchers estimate the method has the potential to sequester billions of tons of carbon, helping slow global climate trends. Other major projects are underway across the globe and have collectively raised over a quarter-billion dollars. [...]

Terradot was founded in 2022 at Stanford, growing out of an independent study between James Kanoff, an undergraduate seeking large-scale carbon removal solutions, and Scott Fendorf, an Earth science professor. Terradot ran a pilot project across 250 hectares in Mexico and began operations in Brazil in late 2023. Since then, the company has spread about 100,000 tons of rock over 4,500 hectares. It has signed contracts to remove about 300,000 tons of carbon dioxide and is backed by a who's who of Silicon Valley. It expects to deliver its first carbon removal credit -- representing one metric ton of verified carbon dioxide removed -- by the end of this year and then scale up from there.

Doug Whitney carries a genetic mutation that guaranteed he would develop Alzheimer's disease in his late forties or early fifties. His mother and nine of her thirteen siblings died from the disease. His oldest brother died at 45. The mutation has decimated his family for generations. Whitney is now 76 and remains cognitively healthy. The New York Times has a fascinating long read on Whitney and things happening around him.

Scientists at Washington University School of Medicine in St. Louis have studied Whitney for 14 years. They extract his cerebrospinal fluid and conduct brain scans during his periodic visits from Washington State. His brain contains heavy amyloid deposits but almost no tau tangles in regions associated with dementia. Tau accumulation correlates directly with cognitive decline. Whitney accumulated tau only in his left occipital lobe, an area that does not play a major role in Alzheimer's.

Researchers identified several possibly protective factors in Whitney's biology. His immune system produces a lower inflammatory response than other mutation carriers. He has unusually high levels of heat shock proteins, which prevent proteins from misfolding. Scientists believe his decade working in Navy engine rooms at temperatures reaching 110 degrees may have driven this accumulation. He also carries three gene variants his afflicted relatives lack. His son Brian inherited the mutation and remains asymptomatic at 43. Brian received anti-amyloid drugs in clinical trials. Researchers published their findings on Whitney in Nature Medicine. They described the study as a call for other scientists to help solve the case.

eBird, now the world's largest citizen science project with over 2 billion bird observations, is transforming ornithology by turning casual birders (and even TikTok-using kids) into vital contributors to global research and conservation. Slashdot reader alternative_right shares a report from Phys.org: The Cornell Lab of Ornithology has been one of the most influential organizations in the world when it comes to encouraging people to engage in natural history projects. While some form of amateur involvement in science projects has been around since 1900, when the Audubon Society organized the first Christmas Bird Count, it was the Cornell Lab that formalized citizen science as a sound and reliable means of collecting data on birds.

It didn't take much thought to realize that one of the richest sources of information about birds resided in the notebooks virtually every birder has kept, often from childhood. It's a given that birdwatchers list everything. The problem is that zillions of such notebooks sit forgotten in drawers or in dusty boxes in the attic. If only all of that information could be gathered together, organized in sensible ways and then made available to anyone who wanted to use it. What a resource that would be!

After lots of trials and discussion, a small team at the Lab came up with the idea of eBird. It started in a humble way back in 2002, as simply somewhere birders could store their records in a central location. Today, "humble" is no longer an appropriate description. In 2022, its 20th anniversary year, a total of more than 1.3 billion records had been received from more than 820,000 participants. In the month of August this year, reports eBird, 123,000 birders submitted 1.6 million lists of sightings. It has now hit a total of 2 billion bird observations since inception.

An anonymous reader quotes a report from The Guardian: MEPs voted on Wednesday by 355 in favor to 247 against to reserve names such as "steak", "burger" and "sausage" exclusively for products derived from meat, a longstanding demand of farm unions. In order to come into effect, the idea would have to be approved by a majority of the EU's 27 member states, which is far from certain. The vote is a victory for the French centre-right MEP Celine Imart, who drafted the amendment to legislation intended to strengthen the position of farmers in the food supply chain.

Imart, who is also a cereals farmer in north-west France, said: "A steak, an escalope or a sausage are products from our livestock, not laboratory art nor plant products. There is a need for transparency and clarity for the consumer and recognition for the work of our farmers." She argues the proposal is in line with EU rules that already ban the use of terms such as "milk" and "yoghurt" for non-dairy products.

The European parliament rejected a ban on meaty names for plant-based products in 2020, but the 2024 elections shifted the parliament to the right, bringing in more lawmakers who seek close ties with farmers. Opposition was led by Green MEPs, who decried what they saw as a populist move to rename plant-based foods. "Veggie burgers, seitan schnitzel and tofu sausage do not confuse consumers, only rightwing politicians," Thomas Waitz, an Austrian Green MEP, said after the vote. "This tactic is a diversion and a pathetic smokescreen. No farmer will earn more money or secure their future with this ban."

Amazon Pharmacy will begin offering prescription pickup kiosks at its One Medical clinics starting in Los Angeles this December, allowing patients to collect common medications like antibiotics and inhalers without waiting for delivery. Reuters reports: The kiosks will be the first in-person pick-up service offered by Amazon Pharmacy, which has been providing prescription services primarily by delivery, said Hannah McClellan Richards, a vice president at Amazon Pharmacy. One Medical offers a membership structure that allows patients to access primary and urgent care at a subscription fee of $199 annually. Patients without a membership are still able to book an appointment and would be able to use the kiosk, the company said.

Richards said in an interview that the company plans to expand the kiosk model outside of California in 2026 and is in talks with external health systems to introduce the machines through partnerships. Amazon does not plan to offer medicines that must be refrigerated, such as GLP-1 weight-loss drugs, or more tightly regulated prescriptions like controlled pain medicines through the kiosk. Inventory for each kiosk will be tailored to the provider, and patients would be able to consult a company pharmacist virtually, Amazon said in a press release.

Susumu Kitagawa, Richard Robson, and Omar M. Yaghi were awarded the Nobel Prize in Chemistry on Wednesday for the development of molecular building blocks with spaces large enough that gases and other chemicals can flow through them. The New York Times: The cavities on the inside are "almost like rooms in a hotel, so that guest molecules can enter and also exit again from the same material," Heiner Linke, chair of the Nobel Committee for Chemistry, said during the announcement of the award. The laureates' discoveries, he added, pave the way for the creation of materials that can separate toxic chemicals from wastewater or harvest water molecules in a desert.

The laureates' work started with experiments by Dr. Robson in the 1980s and gradually developed over a period of about 15 years. "It takes time for science to be recognized, and it takes multiple workers in the field with different approaches," said Dorothy Phillips, president of the American Chemical Society. The three laureates will share a prize of 11 million Swedish kronor, or around $1.17 million.

XXongo writes: A New York times article suggests that merging the diagnosis of Asperger's syndrome into the Autism diagnosis in 2013, thus creating the "autism spectrum disorder," was not helpful (paywalled; alternative source). That broadening of the diagnosis, along with the increasing awareness of the disorder, is largely responsible for the steep rise in autism cases that Health Secretary Robert F. Kennedy Jr. has called "an epidemic" and has attributed to theories of causality that mainstream scientists reject, like vaccines and, more recently, Tylenol. But the same diagnosis now applies to both people who are non-verbal, frequently engage in self-destructive behavior such as pounding their heads against the floor, and may require full-time care, but also to people who are merely somewhat socially awkward, possibly engage in repetitive behaviors, and have a narrow range of interests. "Everything changed when we included Asperger's [in the diagnosis of autism]," said Dr. Eric Fombonne, a psychiatrist and researcher at Oregon Health & Science University. He noted that in the earliest studies of autism rates, 75% of people with the diagnosis had intellectual disabilities. Now, only about a third do.

The New York Times: John Clarke, Michel H. Devoret and John M. Martinis were awarded the Nobel Prize in Physics on Tuesday in Sweden for showing that two properties of quantum mechanics, the physical laws that rule the subatomic realm, could be observed on a system large enough to see with the naked eye. They will share a prize of 11 million Swedish kroner, or around $1.17 million.

"There is no advanced technology today that does not rely on quantum mechanics," Olle Eriksson, chairman of the Nobel Committee for Physics, said during the announcement of the award. The laureates' discoveries, he added, paved the way for technologies like the cellphone, cameras and fiber optic cables.

It also helped lay the groundwork for current attempts to build a quantum computer, a device that could compute and process information at speeds that would not be possible with classical computer. Martinis worked at Google from 2014 to 2020 to build a quantum computer and led the quantum supremacy experiment in 2019. Devoret is cited in Google's recent breakthrough where its Willow quantum chip solved a problem in five minutes that the world's most advanced supercomputer could never solve.

The three laureates conducted experiments with electrical circuits that demonstrated quantum mechanical tunneling and quantized energy levels in systems large enough to hold in the hand. Clarke is a professor at the University of California, Berkeley. Devoret joined his research group in the 1980s and is now at Yale University and UC Santa Barbara. Martinis also joined the group in the 1980s and is currently at UC Santa Barbara and co-founded Qolab, a startup developing utility-scale superconducting quantum computers.

alternative_right shares a report from ScienceDaily: Scientists may have finally uncovered the mystery behind ultra-high-energy cosmic rays -- the most powerful particles known in the universe. A team from NTNU suggests that colossal winds from supermassive black holes could be accelerating these particles to unimaginable speeds. These winds, moving at half the speed of light, might not only shape entire galaxies but also fling atomic nuclei across the cosmos with incredible energy. [...]

But what on earth does that mean? The Milky Way is the neighborhood in the universe where you and I live. Our Sun and solar system are part of this galaxy, along with at least 100 billion other stars. "There is a black hole called Sagittarius-A* located right in the centre of the Milky Way. This black hole is currently in a quiet phase where it isn't consuming any stars, as there is not enough matter in the vicinity," [said postdoctoral fellow Enrico Peretti from the Universite Paris Cite]. This contrasts with growing, supermassive, active black holes that consume up to several times the mass of our own Sun each year. "A tiny portion of the material can be pushed away by the force of the black hole before it is pulled in. As a result, around half of these supermassive black holes create winds that move through the universe at up to half the speed of light," Peretti said.

We have known about these gigantic winds for approximately ten years. The winds from these black holes can affect galaxies. By blowing away gases, they can prevent new stars from forming, for example. This is dramatic enough in itself, but Oikonomou and her colleagues looked at something else, much smaller, that these winds could be the cause of." It is possible that these powerful winds accelerate the particles that create the ultra-high-energy radiation," said [lead author Domenik Ehlert]. The findings have been published in the journal Monthly Notices of the Royal Astronomical Society.

An anonymous reader quotes a report from The Guardian: The heads of UK physics departments say their subject is facing a national crisis as one in four warns that their university departments are in danger of closing because of funding pressures. In an anonymous survey of department heads by the Institute of Physics (IoP), 26% said they faced potential closure of their department within the next two years, while 60% said they expected courses to be reduced. Four out of five departments said they were making staff cuts, and many were considering mergers or consolidation in what senior physicists described as a severe threat to the UK's future success. [...]

To avoid "irreversible damage", the IoP is asking for immediate government action including funding to support existing labs and research facilities, as well as setting up an "early warning system" to monitor departments at risk of closure, and reduce pressures affecting international student recruitment. In the longer term it is calling for radical reforms in higher education funding to allow universities to meet the full costs of teaching nationally important subjects such as physics. Sir Keith Burnett, the IoP's president and a former chair of physics at Oxford University, said: "While we understand the pressures on public finances, it would be negligent not to sound the alarm for a national capability fundamental to our wellbeing, competitiveness and the defense of the realm.

"We are walking towards a cliff edge but there is still time to avert a crisis which would lead not just to lost potential but to many physics departments shutting down altogether. Physics researchers and talented physics students are our future but if action isn't taken now to stabilize, strengthen and sustain one of our greatest national assets, we risk leaving them high and dry." Thomas said the erosion in value of domestic tuition fees and falling numbers of international students were behind the financial pressures, with smaller physics departments the most at risk. "What that means is we will get more and more concentration of where physics is being taught and lose geographical distribution. That goes against aims of widening participation and means some disadvantaged groups will miss out on opportunities to study physics, and it's important that we recognize that," Thomas said.

AstraZeneca has licensed Algen Biotechnologies' AI-powered gene-editing platform, AlgenBrain, to develop immune-related therapies in a deal worth up to $555 million. Reuters reports: AstraZeneca will get exclusive rights to develop and sell approved therapies, if any, that target immune system-related disorders in exchange for upfront and milestone payments to Algen. AstraZeneca has been advancing its cell and gene therapy capabilities through acquisitions and partnerships as it works towards its target of $80 billion in sales by 2030. Globally too, drugmakers are increasingly turning to artificial intelligence for drug development.

Monday's deal, however, does not include AstraZeneca buying a stake in the company, Algen CEO and co-founder Chun-Hao Huang told Reuters in an interview. "Together with AstraZeneca's deep expertise in translational science and clinical development, we aim to uncover new biological insights to accelerate the development of novel therapies," Huang said. Algen was spun out from the UC Berkeley lab where biochemist Jennifer Doudna pioneered the CRISPR technology that won her the Nobel Prize. The biotech firm's AI platform, AlgenBrain, can map genes to disease outcomes, helping the companies decide their development focus for targeted therapies.

California biotech entrepreneur and former magician Serhat Gumrukcu has been found guilty of orchestrating the 2018 murder of his business rival Gregory Davis, who had threatened to expose Gumrukcu's fraudulent dealings. He faces sentencing in November. SFGATE reports: Seven years ago, Turkish national Serhat Gumrukcu, 42, of Los Angeles, was negotiating a multimillion-dollar biotech merger built off his work on a supposed HIV cure. The deal was put in jeopardy by a former business partner named Gregory Davis, 49, who had threatened to bring legal action against Gumrukcu for fraudulent activities relating to a previous failed oil commodities deal, the U.S. Attorney's Office said in a news release last week. Gumrukcu, a magician-turned-scientist who admitted to buying his medical degree from a Russian university, lived in a Hollywood mansion and partied with Oscar winners and movie producers, according to VTDigger. He stood to make millions from the merger of his biotech company Enochian BioSciences. [...]

In 2017, upon learning that Davis, a father of six from Danville, Vermont, could potentially spoil his fortune-making deal, Gumrukcu set in motion a hit on the former business partner. The murder-for-hire plot involved four men in total, prosecutors said. Gumrukcu had a close friend from Las Vegas, Berk Eratay, approach a third man, Aron Ethridge to find a hit man to kill Davis. The shooter, 37-year-old Montana man Jerry Banks, arrived at Davis' home on Jan. 6, 2018, in a vehicle fitted with flashing red and blue lights and posed as a deputy U.S. marshal. After abducting Davis, Banks shot him dead in the vehicle and left the body partially buried in a snowbank nearby.

Investigators soon narrowed in on Gumrukcu after discovering emails between him and Davis revealing tensions over the failed oil deal. Gumrukcu was interviewed twice by the FBI and made false statements on both occasions, federal prosecutors said. Further inspection of cellphone data, bank information and messages identified the four men involved in the kidnapping and killing of Davis.

Mary E. Brunkow, Fred Ramsdell and Shimon Sakaguchi received the Nobel Prize in Physiology or Medicine on Monday for their discoveries about how the immune system regulates itself. The three researchers split 11 million Swedish kroner ($1.17 million). Their work identified regulatory T cells and the FOXP3 gene that controls them. Dr. Sakaguchi spent more than a decade solving a puzzle about the thymus. He discovered that the immune system has a backup mechanism to stop harmful cells from attacking the body's own tissues. Dr. Brunkow and Dr. Ramsdell found the specific gene responsible for this process while studying mice that developed severe autoimmune disease.

More than 200 clinical trials are now underway based on their research. Cancers attract regulatory T cells to block immune attacks. Researchers are developing drugs to turn the immune system against these cancer cells. In autoimmune diseases, regulatory T cells are missing or defective. The FOXP3 gene provides a starting point for drugs that teach the immune system to stop attacking itself.

If we could remove the 50 most concerning pieces of space debris in low-Earth orbit, there'd be a 50% reduction in the overall debris-generating potential, reports Ars Technica. That's according to Darren McKnight, lead author of a paper presented Friday at the International Astronautical Congress in Sydney, which calculated the objects most likely to collide with other fragments and create more debris. (Russia and the Soviet Union lead with 34 objects, followed by China with 10, the U.S. with three, Europe with two, and Japan with one.) Even just the top 10 were removed, the debris-generating potential drops by 30%.

"The things left before 2000 are still the majority of the problem," he points out, and "76% of the objects in the top 50 were deposited last century." 88% of the objects are post-mission rocket bodies left behind to hurtle through space. "The bad news is, since January 1, 2024, we've had 26 rocket bodies abandoned in low-Earth orbit that will stay in orbit for more than 25 years," McKnight told Ars... China launched 21 of the 26 hazardous new rocket bodies over the last 21 months, each averaging more than 4 metric tons (8,800 pounds). Two more came from US launchers, one from Russia, one from India, and one from Iran. This trend is likely to continue as China steps up deployment of two megaconstellations — Guowang and Thousand Sails — with thousands of communications satellites in low-Earth orbit.

Launches of these constellations began last year. The Guowang and Thousand Sails satellites are relatively small and likely capable of maneuvering out of the way of space debris, although China has not disclosed their exact capabilities. However, most of the rockets used for Guowang and Thousand Sails launches have left their upper stages in orbit. McKnight said nine upper stages China has abandoned after launching Guowang and Thousand Sails satellites will stay in orbit for more than 25 years, violating the international guidelines.

It will take hundreds of rockets to fully populate China's two major megaconstellations. The prospect of so much new space debris is worrisome, McKnight said. "In the next few years, if they continue the same trend, they're going to leave well over 100 rocket bodies over the 25-year rule if they continue to deploy these constellations," he said. "So, the trend is not good...." Since 2000, China has accumulated more dead rocket mass in long-lived orbits than the rest of the world combined, according to McKnight. "But now we're at a point where it's actually kind of accelerating in the last two years as these constellations are getting deployed."
A deputy head of China's national space agency recently said China is "currently researching" how to remove space debris from orbit, according to the article. ("One of the missions China claims is testing space debris mitigation techniques has docked with multiple spacecraft in orbit, but U.S. officials see it as a military threat. The same basic technologies needed for space debris cleanup — rendezvous and docking systems, robotic arms, and onboard automation — could be used to latch on to an adversary's satellite.")

ScienceAlert writes that some of the tiny nanoplastic fragments present in soil "can make their way into the edible parts of vegetables, research has found." A team of scientists from the University of Plymouth in the UK placed radishes into a hydroponic (water-based) system containing polystyrene nanoparticles. After five days, almost 5% of the nanoplastics had made their way into the radish roots. A quarter of those were in the edible, fleshy roots, while a tenth had traveled up to the higher leafy shoots, despite anatomical features within the plants that typically screen harmful material from the soil.

"Plants have a layer within their roots called the Casparian strip, which should act as a form of filter against particles, many of which can be harmful," says physiologist Nathaniel Clark. "This is the first time a study has demonstrated nanoplastic particles could get beyond that barrier, with the potential for them to accumulate within plants and be passed on to anything that consumes them...."

There are some limitations to the study, as it didn't use a real-world farming setup. The concentration of plastics in the liquid solution is higher than estimated for soil, and only one type of plastic and one kind of vegetable were tested. Nevertheless, the basic principle stands: the smallest plastic nanoparticles can apparently sneak past protective barriers in plants, and from there into the food we eat... "There is no reason to believe this is unique to this vegetable, with the clear possibility that nanoplastics are being absorbed into various types of produce being grown all over the world," says Clark.
The research has been published in Environmental Research.

Currently DNA synthesis companies "deploy biosecurity software designed to guard against nefarious activity," reports the Washington Post, "by flagging proteins of concern — for example, known toxins or components of pathogens." But Microsoft researchers discovered "up to 100 percent" of AI-generated ricin-like proteins evaded detection — and worked with a group of leading industry scientists and biosecurity experts to design a patch. Microsoft's chief science officer called it "a Windows update model for the planet.

"We will continue to stay on it and send out patches as needed, and also define the research processes and best practices moving forward to stay ahead of the curve as best we can."

But is that enough? Outside biosecurity experts applauded the study and the patch, but said that this is not an area where one single approach to biosecurity is sufficient. "What's happening with AI-related science is that the front edge of the technology is accelerating much faster than the back end ... in managing the risks," said David Relman, a microbiologist at Stanford University School of Medicine. "It's not just that we have a gap — we have a rapidly widening gap, as we speak. Every minute we sit here talking about what we need to do about the things that were just released, we're already getting further behind."
The Washington Post notes not every company deploys biosecurity software. But "A different approach, biosecurity experts say, is to ensure AI software itself is imbued with safeguards before digital ideas are at the cusp of being brought into labs for research and experimentation." "The only surefire way to avoid problems is to log all DNA synthesis, so if there is a worrisome new virus or other biological agent, the sequence can be cross-referenced with the logged DNA database to see where it came from," David Baker, who shared the Nobel Prize in chemistry for his work on proteins, said in an email.

An anonymous reader shared this report from the Washington Post: Women tend to live longer than men. There are traditional explanations: Men smoke more. They drink more. They tend to engage in riskier behavior. But the fact that this lifespan gap holds true regardless of country or century indicates something deeper is also at play.

A growing body of evidence suggests that women's relative longevity may derive, in part, from having double X chromosomes, a redundancy that protects them against harmful mutations. That theory was further bolstered Wednesday with the publication of the most sweeping analysis to date of the lifespan differences between males and females in more than 1,000 mammal and bird species...

If a baby has a pair of X chromosomes, she's a girl. If the baby inherits an X chromosome and a Y chromosome, he's a boy. In birds, however, the situation is reversed. Female birds have a pair of unlike sex chromosomes while males have the like pair... For their study, Colchero, Staerk and their colleagues collected data on the lifespans of 528 mammal species and 648 bird species kept in zoos. The team found that most other mammals are like humans, with the females of nearly three-fourths of mammal species outliving their male counterparts. But in birds, 68 percent of species studied showed a bias toward male longevity, as expected from their chromosomal makeup.

"A small number of researchers are making real progress trying to create computers out of living cells," reports the BBC: Among those leading the way are a group of scientists in Switzerland, who I went to meet. One day, they hope we could see data centres full of "living" servers which replicate aspects of how artificial intelligence (AI) learns — and could use a fraction of the energy of current methods.

That is the vision of Dr Fred Jordan, co-founder of the FinalSpark lab I visited. We are all used to the ideas of hardware and software in the computers we currently use. The somewhat eyebrow-raising term Dr Jordan and others in the field use to refer to what they are creating is "wetware". In simple terms, it involves creating neurons which are developed into clusters called organoids, which in turn can be attached to electrodes — at which point the process of trying to use them like mini-computers can begin...

For FinalSpark, the process begins with stem cells derived from human skin cells, which they buy from a clinic in Japan. The actual donors are anonymous... In the lab, FinalSpark's cellular biologist Dr Flora Brozzi handed me a dish containing several small white orbs. Each little sphere is essentially a tiny, lab-grown mini-brain, made out of living stem cells which have been cultured to become clusters of neurons and supporting cells — these are the "organoids"... After undergoing a process which can last several months, the organoids are ready to be attached to an electrode and then prompted to respond to simple keyboard commands... Electrical stimulations are important first steps towards the team's bigger goal of triggering learning in the biocomputer's neurons so they can eventually adapt to perform tasks...

FinalSpark are not the only scientists working in the biocomputing space. Australian firm Cortical Labs announced in 2022 that it had managed to get artificial neurons to play the early computer game Pong. In the US, researchers at Johns Hopkins University are also building "mini-brains" to study how they process information — but in the context of drug development for neurological conditions like Alzheimer's and autism.
Thanks to long-time Slashdot reader fjo3 for sharing the news.

Jeff Bezos told an audience on Friday that gigawatt-scale data centers will be built in space within the next ten to twenty years. The Amazon founder said these orbital facilities would eventually outperform their terrestrial counterparts because space offers uninterrupted solar power around the clock.

Bezos was speaking in a fireside chat with Ferrari and Stellantis Chairman John Elkann. He said the giant training clusters needed for AI would be better built in space because there are no clouds, rain or weather to interrupt power generation. Bezos predicted that space-based data centers would beat the cost of Earth-based ones within a couple of decades. He described the shift as part of a broader pattern that has already occurred with weather satellites and communication satellites. The next steps would be data centers and then other kinds of manufacturing.

Air pollution increases the likelihood of people becoming frail in middle and old age, according to an international review of studies. The Guardian: The review team found 10 studies that looked at outdoor air pollution and frailty. The people studied came from 11 countries including China, the UK, Sweden, South Africa and Mexico. Two of the studies showed that men were more vulnerable than woman, with a stronger association between particle pollution and frailty. The risk of frailty increased with outdoor particle pollution. For the UK, this could mean about 10-20% of frailty cases are attributable to air pollution.

Exposure to secondhand smoking was the environmental factor that presented the greatest risk of frailty. The risk of frailty was increased by about 60% for people who breathed other people's smoke at home. Using solid fuels for cooking or home heating also carried an extra risk of frailty. This was about half the risk of living with a smoker, based on studies from six countries.

An anonymous reader quotes a report from MIT Technology Review: A team at Microsoft says it used artificial intelligence to discover a "zero day" vulnerability in the biosecurity systems used to prevent the misuse of DNA. These screening systems are designed to stop people from purchasing genetic sequences that could be used to create deadly toxins or pathogens. But now researchers led by Microsoft's chief scientist, Eric Horvitz, says they have figured out how to bypass the protections in a way previously unknown to defenders.The team described its work today in the journalScience.

Horvitz and his team focused on generative AI algorithms that propose new protein shapes. These types of programs are already fueling the hunt for new drugs at well-funded startups like Generate Biomedicines and Isomorphic Labs, a spinout of Google. The problem is that such systems are potentially "dual use." They can use their training sets to generate both beneficial molecules and harmful ones. Microsoft says it began a "red-teaming" test of AI's dual-use potential in 2023 in order to determine whether "adversarial AI protein design" could help bioterrorists manufacture harmful proteins.

The safeguard that Microsoft attacked is what's known as biosecurity screening software. To manufacture a protein, researchers typically need to order a corresponding DNA sequence from a commercial vendor, which they can then install in a cell. Those vendors use screening software to compare incoming orders with known toxins or pathogens. A close match will set off an alert. To design its attack, Microsoft used several generative protein models (including its own, called EvoDiff) to redesign toxins -- changing their structure in a way that let them slip past screening software but was predicted to keep their deadly function intact. "This finding, combined with rapid advances in AI-enabled biological modeling, demonstrates the clear and urgent need for enhanced nucleic acid synthesis screening procedures coupled with a reliable enforcement and verification mechanism," says Dean Ball, a fellow at the Foundation for American Innovation, a think tank in San Francisco.

Bruce66423 shares a report from The Guardian: Those diagnosed as small children typically have distinct genetic profile from those diagnosed later, [finds an international study based on genetic data from more than 45,000 autistic people in Europe and the U.S]. So, there's more than one condition out there that's being diagnosed as "autism." This, of course, messes with the debate about causes; one version of autism may be caused by something for which the evidence is very weak overall. "The term 'autism' likely describes multiple conditions," said Dr Varun Warrier, from Cambridge's department of psychiatry, senior author of the research. "For the first time, we have found that earlier and later diagnosed autism have different underlying biological and developmental profiles."

"It is a gradient," added Warrier. "There are also many other factors that contribute to age of diagnosis, so the moment you go from averages to anything that is applicable to an individual, it's false equivalency."

The analysis has been published in the journal Nature.

An anonymous reader shares a report: It's not the vibes; Earth is literally getting darker. Scientists have discovered that our planet has been reflecting less light in both hemispheres, with a more pronounced darkening in the Northern hemisphere, according to a study published on Monday in Proceedings of the National Academy of Sciences.

The new trend upends longstanding symmetry in the surface albedo, or reflectivity, of the Northern and Southern hemispheres. In other words, clouds circulate in a way that equalizes hemispheric differences, such as the uneven distribution of land, so that the albedos roughly match -- though nobody knows why. "There are all kinds of things that people have noticed in observations and simulations that tend to suggest that you have this hemispheric symmetry as a kind of fundamental property of the climate system, but nobody's really come up with a theoretical framework or explanation for it," said Norman Loeb, a physical scientist at NASA's Langley Research Center, who led the new study. "It's always been something that we've observed, but we haven't really explained it fully."

To study this mystery, Loeb and his colleagues analyzed 24 years of observations captured since 2000 by the Clouds and the Earth's Radiant Energy System (CERES), a network of instruments placed on several NOAA and NASA satellites. Instead of an explanation for the strange symmetry, the results revealed an emerging asymmetry in hemispheric albedo; though both hemispheres are darkening, the Northern hemisphere shows more pronounced changes which challenges "the hypothesis that hemispheric symmetry in albedo is a fundamental property of Earth," according to the study.

Scientists have discovered complex organic molecules within the icy plume erupting from Saturn's moon Enceladus, strengthening the case that its hidden saltwater ocean may harbor the conditions for life. The Guardian reports: The sixth largest of Saturn's moons, Enceladus has become one of the leading contenders in the search for bodies that could harbor extraterrestrial life, with the Cassini mission -- which ended in 2017 -- revealing the moon has a plume of water ice grains and vapors erupting from beneath the surface at its south pole. The phenomenon has since been captured by the James Webb space telescope, with the plume reaching nearly 6,000 miles into space. The source of this material is thought to be a saltwater ocean that lies beneath the moon's icy crust.

Now researchers studying data from the Cassini mission say they have discovered organic substances within the plume, with some types of molecule detected there for the first time. Dr Nozair Khawaja, a planetary scientist at Freie University Berlin and lead author of the work, said the results increased the known complexity of the chemistry that is happening below the surface of Enceladus. "When there is complexity happening, that means that the habitable potential of Enceladus is increasing right now," he said. Writing in the journal Nature Astronomy, Khawaja and colleagues reported how their previous work had revealed the presence of organic substances and salts within ice grains found in a ring of Saturn, known as the "E-ring," that is composed of material ejected from Enceladus. [...]

While the new findings do not show that there is life on Enceladus, Khawaja said they indicate there are complex chemical pathways at play that could lead to the formation of substances that could be biologically relevant. The results, he added, support plans by the European Space Agency (ESA) to investigate the moon for signs of life. "I think all the signals are green here for Enceladus," Khawaja said. The findings add momentum to ESA's proposed mission to directly search for biological signs around 2042. According to the ESA, the mission will consist of an orbiter around Enceladus that will also fly through the plumes, as well as a lander that will touch down in the south pole region of the moon.

Jane Goodall, world-renowned primatologist, anthropologist, and conservationist, has died at the age of 91 while on a speaking tour in California. The British primatologist's "discoveries as an ethologist revolutionized science, and she was a tireless advocate for the protection and restoration of our natural world," according to the institute she founded. From a report: Goodall was only 26 years old when she first traveled to Tanzania and began her important research on chimpanzees in the wild. Throughout her study of the species, Goodall proved that primates display an array of similar behaviors to humans, such as the ability to develop individual personalities and make and use their own tools. Among the most surprising discoveries Goodall made was "how like us" the chimpanzees are, she told ABC News in 2020.

"Their behavior, with their gestures, kissing, embracing, holding hands and patting on the back," she said. "... The fact that they can actually be violent and brutal and have a kind of war, but also loving an altruistic." That discovery is considered one of the great achievements of 20th-century scholarship, according to the Jane Goodall Institute. [...] Goodall's research garnered both scientific honors and mainstream fame, and she was credited with paving the way for a rise in women pursuing careers in STEM (science, technology, engineering and math) over the years. The number of women in STEM has increased from 7% to 26% in the six last decades, according to The Jane Goodall Institute, which cited census information from 1970 to 2011.

In 1991, she also founded Roots & Shoots, a global humanitarian and environmental program for young people. She was named a United Nations Messenger of Peace in April 2002. The anthropologist continued to lend her voice to environmental causes well into her 80s and 90s. In 2019, Goodall acknowledged the climate crisis and the importance of mitigating further warming, telling ABC News that the planet is "imperiled." "We are definitely at a point where we need to make something happen," she said.

"We are imperiled. We have a window of time. I'm fairly sure we do. But, we've got to take action." Goodall even partnered with Apple in 2022 to encourage customers to recycle their devices to reduce individual carbon footprint and cut down on unnecessary mineral mining around the world. "Yes, people need to make money, but it is possible to make money without destroying the planet," Goodall told ABC News at the time. "We've gone so far in destroying the planet that it's shocking."

alternative_right shares a report from Phys.org: For the first time, a new study has tested the effectiveness of trigger warnings in real life scenarios, revealing that the vast majority of young adults choose to ignore them. A new Flinders University study has found that nearly 90% of young people who saw a trigger warning still chose to view the content, saying that they did so out of curiosity, rather than because they felt emotionally prepared or protected. The findings published in the Journal of Behavior Therapy and Experimental Psychiatry aligned with a growing body of lab-based research suggesting that trigger warnings rarely lead to the avoidance of potentially distressing material.

An anonymous reader quotes a report from the BBC: US scientists have, for the first time, made early-stage human embryos by manipulating DNA taken from people's skin cells and then fertilizing it with sperm. The technique could overcome infertility due to old age or disease, by using almost any cell in the body as the starting point for life. It could even allow same-sex couples to have a genetically related child. [...]

The Oregon Health and Science University research team's technique takes the nucleus -- which houses a copy of the entire genetic code needed to build the body -- out of a skin cell. This is then placed inside a donor egg that has been stripped of its genetic instructions. So far, the technique is like the one used to create Dolly the Sheep -- the world's first cloned mammal -- born back in 1996. However, this egg is not ready to be fertilized by sperm as it already contains a full suite of chromosomes.

You inherit 23 of these bundles of DNA from each of your parents for a total of 46, which the egg already has. So the next stage is to persuade the egg to discard half of its chromosomes in a process the researchers have termed "mitomeiosis" (the word is a fusion of mitosis and meiosis, the two ways cells divide). The study, published in the journal Nature Communications, showed 82 functional eggs were made. These were fertilized with sperm and some progressed onto the early stages of embryos development. None were developed beyond the six-day-stage.

The technique is far from polished as the egg randomly chooses which chromosomes to discard. It needs to end up with one of each of the 23 types to prevent disease, but ends up with two of some and none of others. There is also a poor success rate (around 9%) and the chromosomes miss an important process where they rearrange their DNA, called crossing over. Prof Mitalipov, a world-renowned pioneer in the field, told me: "We have to perfect it. "Eventually, I think that's where the future will go because there are more and more patients that cannot have children."

Cancer rates among people aged 15 to 49 have increased 10% since 2000 even as rates have fallen among older populations. Young women face an 83% higher cancer rate than men in the same age range. A 150,000-person study presented at the American Association for Cancer Research meeting found millennials appear to be aging biologically faster than previous generations based on blood biomarkers. That acceleration was associated with up to 42% increased risk for certain cancers including lung, gastrointestinal and uterine malignancies.

Researchers are examining the "exposome" -- the full range of environmental exposures across a person's life. Studies have linked early-onset cancers to medications taken during pregnancy, ultra-processed foods that now account for more than half of daily calorie intake in the United States, circadian rhythm disruption from artificial light and shift work, and chemical exposures. Gary Patti at Washington University is using zebrafish exposed to known and suspected carcinogens to track tumor development. His lab has developed systems to scan blood samples for tens of thousands of chemicals simultaneously to identify signatures appearing more frequently in early-onset cancer patients.

BrianFagioli shares a report from NERDS.xyz: NASA has awarded Solstar Space a $150,000 SBIR Phase I contract to develop a Lunar Wi-Fi Access Point (LWIFI-AP). The system is designed to provide wireless connectivity for astronauts, rovers, and orbiting spacecraft as part of the Artemis and Commercial Lunar Payload Services programs. Solstar's goal is to build a space-rated, multi-band, multi-protocol access point that can survive radiation, extreme lunar temperatures, and other harsh conditions. NASA has identified Wi-Fi and 3GPP standards as core communication needs across mission systems ranging from the Human Landing System and Lunar Terrain Vehicle to the Lunar Gateway.

Although this is only an early-stage contract, Solstar's proposal addresses a clear gap in space-qualified networking hardware. The company says that just as Wi-Fi transformed daily life on Earth, it will be equally important for living and working on the Moon. If the project advances, astronauts could soon be relying on familiar wireless technology that has been adapted for one of the most challenging environments in existence.

Sen. Mark Kelly and three Democratic colleagues urged appropriations leaders to block funding for moving space shuttle Discovery from the Smithsonian's Udvar-Hazy Center in Virginia to Houston, arguing the transfer would waste taxpayer money, risk permanent damage, and restrict public access. The relocation, pushed by Texas senators Cornyn and Cruz under a new law, carries an estimated cost of nearly $400 million. Ars Technica reports: "Why should hundreds of millions of taxpayer dollars be spent just to jeopardize a piece of American history that's already protected and on display?" wrote Kelly in a social media post on Friday. "Space Shuttle Discovery belongs at the Smithsonian, where millions of people, including students and veterans, go to see it for free." In a letter sent on the same day to the leadership of the Senate Committee on Appropriations, Kelly and his three colleagues cautioned that any effort to transfer the winged orbiter would "waste taxpayer dollars, risk permanent damage to the shuttle, and mean fewer visitors would be able to visit it." "It is worth noting that there is little evidence of broad public demand for such a move," wrote Kelly, Warner, Kaine, and Durbin.

In the letter, the senators asked that committee chair Susan Collins (R-Maine) and vice chair Patty Murray (D-Wash.) block funding for Discovery's relocation in both the fiscal year 2026 Interior-Environment appropriations bill and FY26 Commerce, Justice, Science appropriations bill. [...] "Houston's disappointment in not being selected is wholly understandable," the four senators wrote, "but removing an item from the National Collection is not a viable solution." [...] "There are also profound financial challenges associated with this transfer," wrote Kelly. Warner, Kaine, and Durbin. "The Smithsonian estimates that transporting Discovery from Virginia to Houston could cost more than $50 million, with another $325 million needed for planning, exhibit reconstruction, and new facilities." "Dedicating hundreds of millions of taxpayer dollars to move an artifact that is already housed, displayed, and preserved in a world-class facility is both inefficient and unjustifiable," the senators wrote.

Then there are the logistical challenges with relocating Discovery, which could result in damaging it, "permanently diminishing its historical and cultural value for future generations." "Moving Discovery by barge or road would be far more complex [than previous shuttle moves], exposing it to saltwater, weather, and collision risks across a journey several times longer," the letter reads. "As a one-of-a-kind artifact that has already endured the stresses of spaceflight, Discovery is uniquely vulnerable to these hazards. The heat tiles that enabled repeated shuttle missions become more fragile with age, and they are irreplaceable." Kelly, who previously lived in Houston when he was part of the space program, agrees that the city is central to NASA's human spaceflight efforts, but, along with Warner, Kaine, and Durbin, points out that displaying Discovery would come with another cost: an admission fee, limiting public access to the shuttle. "The Smithsonian is unique among museums for providing visitors with access to a national treasure meant to inspire the American public without placing economic barriers," wrote the senators.

Researchers in Texas confirmed the first documented wild hybrid between a blue jay and a green jay -- a rare pairing that is likely a result of climate change and habitat shifts. Slashdot reader fjo3 shares a report from CNN: "We think it's the first observed vertebrate that's hybridized as a result of two species both expanding their ranges due, at least in part, to climate change," said Brian Stokes, a doctoral student of biology at the University of Texas at Austin and first author of the study published September 10 in the journal Ecology and Evolution. The vividly colored green jay is found in parts of South and Central America, Mexico and a limited portion of southern Texas. But since 2000, the tropical bird's territory has expanded north by hundreds of kilometers -- more than 100 miles and about 2 degrees of latitude -- along the Rio Grande and up toward San Antonio, said study coauthor Timothy Keitt.

Avid birders across Central Texas have taken note, sharing sightings of the emerald birds on social media and apps like eBird. Keitt, a professor of integrative biology at UT Austin, has been keeping tabs on their rapid northward creep since 2018. "They're pretty unmistakable in the field," he told CNN. "You see a green jay and you absolutely know that it's a green jay." Stokes joined Keitt's project a few years later, trapping birds to take blood samples for genetic analysis and releasing them back into the wild. While monitoring social media for green jay sightings in May 2023, Stokes came across an intriguing post on a Facebook group called Texbirds. A woman in a suburb of San Antonio shared a photo of an unusual bird that didn't look like any jay Stokes or Keitt had ever seen.

"He happened to notice that this person posted a picture of this odd jay, and immediately told me, and we got in the car and drove down to find it right away," Keitt said. He and Stokes described their finding as one of the "increasingly unexpected outcomes" that arise when global warming and land development converge to drive animal populations to new habitat ranges. This, they wrote, can lead to unpredictable animal interactions -- in this case, between a tropical species and a temperate one -- and create never-before-seen ecological communities.

A review of 62 scientific studies published in Osteoporosis International found that microplastics weaken bones by disrupting bone marrow stem cells and stimulating osteoclasts, cells that degrade bone tissue. Laboratory experiments found the particles reduce cell viability, induce premature cellular aging, modify gene expression, and trigger inflammatory responses. Animal studies found microplastic accumulation decreases white blood cell counts and deteriorates bone microstructure, creating irregular cell structures that increase fracture risk. Rodrigo Bueno de Oliveira from the State University of Campinas in Brazil said the effects interrupted skeletal growth in test animals.

"As awareness grows around the dangers of head trauma in sports, a small number of professional fighters and football players are turning to a psychedelic called ibogaine for treatment," reports the Los Angeles Times.

They note that the drug's proponents "tout its ability to treat addiction, post-traumatic stress disorder and traumatic brain injury, or TBI. " Ibogaine, which is derived from a West African shrub, is a Schedule 1 drug in America with no legal medical uses, and experts urge caution because of the need for further studies. But the results, several athletes say, are "game-changing".... Although athletes are just discovering ibogaine, the drug is well known within the veteran community, which experiences high rates of brain injury and PTSD. In Stanford's study on the effects of ibogaine on special forces veterans, participants saw average reductions of 88% in PTSD symptoms, 87% in depression symptoms and 81% in anxiety symptoms. They also exhibited improvements in concentration, information processing and memory.

"No other drug has ever been able to alleviate the functional and neuropsychiatric symptoms of traumatic brain injury," Dr. Nolan Williams, a professor of psychiatry and behavioral sciences, said in a statement on the results. "The results are dramatic, and we intend to study this compound further...."

States can work faster than the federal government by carving out exemptions for supervised ibogaine therapy programs, similar to what Oregon has done with psilocybin therapy. Many states have also opted to legalize marijuana for medicinal or recreational use... In June, Texas approved a historic $50-million investment in state funding to support drug development trials for ibogaine, inspired by the results seen by veterans. Arizona legislators approved $5 million in state funding for a clinical study on ibogaine in March, and California legislators are pushing to fast-track the study of ibogaine and other psychedelics.

"The internet is full of people claiming to uncover conspiracies in politics and business..." reports the Wall Street Journal.

"Now an unlikely new villain has been added to the list: theoretical physicists," they write, saygin resentment of scientific authority figures "is the major attraction of what might be called 'conspiracy physics'." In recent years, a group of YouTubers and podcasters have attracted millions of viewers by proclaiming that physics is in crisis. The field, they argue, has discovered little of importance in the last 50 years, because it is dominated by groupthink and silences anyone who dares to dissent from mainstream ideas, like string theory... Most fringe theories are too arcane for listeners to understand, but anyone can grasp the idea that academic physics is just one more corrupt and self-serving establishment... In this corner of the internet, the scientist Scott Aaronson has written, "Anyone perceived as the 'mainstream establishment' faces a near-insurmountable burden of proof, while anyone perceived as 'renegade' wins by default if they identify any hole whatsoever in mainstream understanding...

As with other kinds of authorities, there are reasonable criticisms to be made of academic physics. By some metrics, scientific productivity has slowed since the 1970s. String theory has not fulfilled physicists' early dreams that it would become the ultimate explanation of all forces and matter in our universe. The Large Hadron Collider, the world's largest particle accelerator, has delivered fewer breakthroughs than scientists expected when it turned on in 2010. But even reasonable points become hard to recognize when expressed in the ways YouTube incentivizes. Conspiracy physics videos with titles like "They Just Keep Lying" are full of sour sarcasm, outraged facial expressions and spooky music...

Leonard Susskind, director of the Stanford Institute for Theoretical Physics, says physicists need to be both more sober and more forceful when addressing the public. The limits of string theory should be acknowledged, he says, but the idea that progress has slowed isn't right. In the last few decades, he and other physicists have figured out how to make progress on the vast project of integrating general relativity and quantum mechanics, the century-old pillars of physics, into a single explanation of the universe.
The bitter attacks on leading physicists get a succinct summary in the article from Chris Williamson, a "Love Island" contestant turned podcast host. "This is like 'The Kardashians' for physicists — I love it."

The BBC reports that a million-year-old human skull found in China suggests that the human species "began to emerge at least half a million years earlier than we thought, researchers are claiming in a new study." It also shows that we co-existed with other sister species, including Neanderthals, for much longer than we've come to believe, they say.

The scientists claim their analysis "totally changes" our understanding of human evolution and, if correct, it would certainly rewrite a key early chapter in our history. But other experts in a field where disagreement over our emergence on the planet is rife, say that the new study's conclusions are plausible but far from certain.

The discovery, published in the leading scientific journal Science, shocked the research team, which included scientists from a university in China and the UK's Natural History Museum. "From the very beginning, when we got the result, we thought it was unbelievable. How could that be so deep into the past?" said Prof Xijun Ni of Fudan University, who co-led the analysis. "But we tested it again and again to test all the models, use all the methods, and we are now confident about the result, and we're actually very excited."
Thanks to long-time Slashdot reader sinij for sharing the article.

Long-time Slashdot reader theodp says America's Patent and Trademark Office (USPTO) has granted a patent to Tableau (Salesforce's visual analytics platform) — for a patent covering "Data Processing For Visualizing Hierarchical Data": "A provided data model may include a tree specification that declares parent-child relationships between objects in the data model. In response to a query associated with objects in the data model: employing the parent-child relationships to determine a tree that includes parent objects and child objects from the objects based on the parent-child relationships; determining a root object based on the query and the tree; traversing the tree from the root object to visit the child objects in the tree; determining partial results based on characteristics of the visited child objects such that the partial results are stored in an intermediate table; and providing a response to the query that includes values based on the intermediate table and the partial results."

A set of 15 simple drawings is provided to support the legal and tech gobbledygook of the invention claims. A person can have a manager, Tableau explains in Figures 5-6 of its accompanying drawings, and that manager can also manage and be managed by other people. Not only that, Tableau illustrates in Figures 7-10 that computers can be used to count how many people report to a manager. How does this magic work, you ask? Well, you "generate [a] tree" [Fig. 13] and "traverse a tree" [Fig. 15], Tableau explains. But wait, there's more — you can also display the people who report to a manager in multi-level or nested pie charts (aka Sunburst charts), Tableau demonstrates in Fig. 11.

Interestingly, Tableau released a "pre-Beta" Sunburst chart type in late April 2023 but yanked it at the end of June 2023 (others have long-supported Sunburst charts, including Plotly). So, do you think Tableau should be awarded a patent in 2025 on a concept that has roots in circa-1921 Sunburst charts and tree algorithms taught to first-year CS students in circa-1975 Data Structures courses?