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Medicine

Research Suggests Effects of Shift Work or Jet Lag On Our Body Clocks Can Be Reduced By Simply Changing Meal Times (qz.com) 51

Jonathan Johnston reports via Quartz: Around one in five people in Western countries could be putting their health at risk simply by going to work. This is because working shifts outside of the rest of the population's normal hours has been linked to obesity, diabetes, heart disease, cancer and even declines in brain function. Scientists think this is because our bodies are programmed to run on cycles known as circadian rhythms, and changes in our routine caused by shift work or traveling long distances disrupts those rhythms. But our new research suggests that the effects of shift work or jet lag on our body clocks could be reduced simply by changing the times at which people eat. The key to this theory is the idea that each person doesn't just have a single body clock but rather a complex network of billions of cellular clocks found throughout the body. In humans and other mammals, there is a master clock within a region of the brain called the suprachiasmatic nuclei (SCN) and many peripheral clocks found elsewhere. For our research, we wanted to see how one aspect of this approach -- changing meal times -- affected circadian rhythms. We found that delaying meals by a certain amount caused a similar shift in some peripheral clocks, without changing the master clock. This is important because research in animals suggests peripheral clocks take longer to adjust to a new routine.
The Almighty Buck

Air Force Budget Reveals How Much SpaceX Undercuts Launch Prices (arstechnica.com) 97

An anonymous reader quotes a report from Ars Technica: In 2014, the U.S. Government Accountability Office issued a report on cost estimates for the U.S. Air Force's program to launch national security payloads, which at the time consisted of a fleet of rockets maintained and flown entirely by United Launch Alliance (ULA). The report was critical of the non-transparent nature of ULA's launch prices and noted that the government "lacked sufficient knowledge to negotiate fair and reasonable launch prices" with the monopoly. At around the same time, the new space rocket company SpaceX began to aggressively pursue the opportunity to launch national security payloads for the government. SpaceX claimed to offer a substantially lower price for delivering satellites into various orbits around Earth. But because of the lack of transparency, comparing prices was difficult. The Air Force recently released budget estimates for fiscal year 2018, and these include a run out into the early 2020s. For these years, the budget combines the fixed price rocket and ELC contract costs into a single budget line. (See page 109 of this document). They are strikingly high. According to the Air Force estimate, the "unit cost" of a single rocket launch in fiscal year 2020 is $422 million, and $424 million for a year later. SpaceX sells basic commercial launches of its Falcon 9 rocket for about $65 million. But, for military launches, there are additional range costs and service contracts that add tens of millions of dollars to the total price. It therefore seems possible that SpaceX is taking a loss or launching at little or no profit to undercut its rival and gain market share in the high-volume military launch market. Elon Musk retweeted the article, adding "$300M cost diff between SpaceX and Boeing/Lockheed exceeds avg value of satellite, so flying with SpaceX means satellite is basically free."

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