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Science

Microbe With Bizarrely Tiny Genome May Be Evolving Into a Virus (science.org) 17

sciencehabit shares a report from Science.org: The newly discovered microbe provisionally known as Sukunaarchaeum isn't a virus. But like viruses, it seemingly has one purpose: to make more of itself. As far as scientists can tell from its genome -- the only evidence of its existence so far -- it's a parasite that provides nothing to the single-celled creature it calls home. Most of Sukunaarchaeum's mere 189 protein-coding genes are focused on replicating its own genome; it must steal everything else it needs from its host Citharistes regius, a dinoflagellate that lives in ocean waters all over the world. Adding to the mystery of the microbe, some of its sequences identify it as archaeon, a lineage of simple cellular organisms more closely related to complex organisms like us than to bacteria like Escherichia coli.

The discovery of Sukunaarchaeum's bizarrely viruslike way of living, reported last month in a bioRxiv preprint, "challenges the boundaries between cellular life and viruses," says Kate Adamala, a synthetic biologist at the University of Minnesota Twin Cities who was not involved in the work. "This organism might be a fascinating living fossil -- an evolutionary waypoint that managed to hang on." Adamala adds that if Sukunaarchaeum really does represent a microbe on its way to becoming a virus, it could teach scientists about how viruses evolved in the first place. "Most of the greatest transitions in evolution didn't leave a fossil record, making it very difficult to figure out what were the exact steps," she says. "We can poke at existing biochemistry to try to reconstitute the ancestral forms -- or sometimes we get a gift from nature, in the form of a surviving evolutionary intermediate."

What's already clear: Sukunaarchaeum is not alone. When team leader Takuro Nakayama, an evolutionary microbiologist at Tsukuba, and his colleagues sifted through publicly available DNA sequences extracted from seawater all over the world, they found many sequences similar to those of Sukunaarchaeum. "That's when we realized that we had not just found a single strange organism, but had uncovered the first complete genome of a large, previously unknown archaeal lineage," Nakayama says.

Microbe With Bizarrely Tiny Genome May Be Evolving Into a Virus

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  • what I know about cell biology can be coded in much less than that creature's genome

  • From Naked Lunch p. 67

    "(It is thought that the virus is a degeneration from more complex life form. It may at one time have been capable of independent life. Now has fallen to the borderline between living and dead matter. It can exhibit living qualities only in a host, by using the life of another -- the renunciation of life itself, a falling towards inorganic, inflexible machine, towards dead matter.)

    Cf Nietzsche

    What is falling, push!

  • Yup, it's all just stardust that's stumbled onto replicating patterns of molecules.

    Some patterns are more complex than others, for certain values of complexity.

  • Unlike a bacteria, that have multiple purposes, like also when to pick the kids up from school.

    This is an idiotic basis for the distinction between bacteria and viruses. The comments here will be full of more valid distinctions.

  • Wonder where they learned that behavior, people maybe?

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