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Medicine Government United States

America's Top Three Insurers Reaped $7.3 Billion From Their Drug-Middlemen's Markups, FTC Says (nbcnews.com) 59

America's Federal Trade Commission has been "raising antitrust concerns" about them for years, reports NBC News.

The latest? America's three largest drug middlemen "inflated the costs of numerous life-saving medications by billions of dollars over the past few years, the FTC said in a report Tuesday." The top pharmacy benefit managers (PBMs) — CVS Health's Caremark Rx, Cigna's Express Scripts and UnitedHealth Group's OptumRx — generated roughly $7.3 billion through price hikes over about five years starting in 2017, the FTC said. The "excess" price hikes affected generic drugs used to treat heart disease, HIV and cancer, among other conditions, with some increases more than 1,000% of the national average costs of acquiring the medications, the commission said. The FTC also said these so-called Big Three health care companies — which it estimates administer 80% of all prescriptions in the U.S. — are inflating drug prices "at an alarming rate, which means there is an urgent need for policymakers to address it...."

Some of the steepest drug markups were "hundreds and thousands of percent," according to Tuesday's report, which highlights just how profitable specialty drugs have become for the three leading PBMs. Cancer drugs alone made up nearly half of the $7.3 billion, the commission wrote, with multiple sclerosis medications accounting for another 25%. Dispensing highly marked-up specialty drugs was a massive income stream for the companies in 2021, the FTC found. Out of tens of thousands of drugs dispensed, the top 10 specialty generics alone made up nearly 11% of the companies' pharmacy-related operating income that year, the agency estimated. Across the 51 drugs the agency analyzed, the Big Three's price-markup revenue surged from $522 million in 2017 to $2.1 billion in 2021, the report said.

"The FTC found that 22 percent of specialty drugs dispensed by PBM-affiliated pharmacies were marked up by more than 1,000 percent," reports The Hill, "while 41 percent were marked up between 100 and 1,000 percent. Among those drugs marked up by more than 1,000 percent, half of them were marked up by more than 2,000 percent."

And the nonprofit site progressive news site Common Dreams shares some examples from the FTC's 60-page report: "For the pulmonary hypertension drug tadalafil (generic Adcirca), for example, pharmacies purchased the drug at an average of $27 in 2022, yet the Big Three PBMs marked up the drug by $2,079 and paid their affiliated pharmacies $2,106, on average, for a 30-day supply of the medication on commercial claims," the publication notes. That's a staggering average markup of 7,736%... The new analysis follows a July 2024 report that revealed Big Three PBM-affiliated pharmacies received 68% of the dispensing revenue generated by specialty drugs in 2023, a 14% increase from 2016...

Responding to the FTC report, Emma Freer, senior policy analyst for healthcare at the American Economic Liberties Project — a corporate accountability and antitrust advocacy group — said in a statement Tuesday that "the FTC's second interim report lays bare the blatant profiteering by PBM giants, which are marking up lifesaving drugs like cancer, HIV, and multiple sclerosis treatments by thousands of percent and forcing patients to pay the price."

America's Top Three Insurers Reaped $7.3 Billion From Their Drug-Middlemen's Markups, FTC Says

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  • Defence? (Score:5, Interesting)

    by ukoda ( 537183 ) on Saturday January 18, 2025 @01:52PM (#65099179) Homepage
    As some from a country with free health care and drug prices that are seldom worth considering I will love to hear how you can defend such mark ups?
    • "The Free Market"

      As if a free market for death is a good thing.
      • Re:Defence? (Score:4, Insightful)

        by Tokolosh ( 1256448 ) on Saturday January 18, 2025 @02:06PM (#65099207)

        The US has the exact opposite of a "free market" in healthcare.

        All the high costs and markups are enabled by government regulations, licensing, certificates-of-need, import restrictions, etc. etc. All aided and abetted by the trade union American Medical Association.

        • Re:Defence? (Score:5, Insightful)

          by dfghjk ( 711126 ) on Saturday January 18, 2025 @02:25PM (#65099243)

          LOL that's it! Totally consistent with the article, too!

          You want to find out what the real "exact opposite of a free market" is? Eliminate government regulations. Free markets are not destroyed by regulation, they require it. The greed of unbridled capitalism is the exact opposite of a free market, and that's what we see here.

          • "Unbridled"? If that is the case, why don't just buy some Tadalafil directly from an Indian manufacturer, sell it to your friends, and profit!

            If you can explain to me why this does not happen in our unbridled system, I'll be happy to accept your reasoning. I'm waiting...

      • "The Free Market"

        Ahh yes, well it’s a common misconception. We haven’t had the r in a long time and people keep calling it by the old name. I like the cut of your jib.

    • by Calydor ( 739835 )

      Research and Development.

      Please ignore the fact these drugs earned back their research costs decades ago.

      • by ukoda ( 537183 )
        This article is about "America's three largest drug middlemen". What R&D did the middlemen do, finding the email address of the drug companies that actually incurred those costs?
      • Irrelevant.
        The PBMs do not do research nor do they manufacture.
        They are middle-men.
          Think of them as the warehouse that buys food from the farmers, stores and ships it to bakeries and groceries.
        The analogy breaks down in that they don't Even do that much. They're just there in the middle.

      • Research and Development. Please ignore the fact these drugs earned back their research costs decades ago.

        Insurance companies don't (usually) develop drugs, so not sure R&D factors into the middle-men price mark-ups, even when those companies are also owned by the insurance companies themselves. In these cases, they're probably separate companies for tax, PR, and/or liability reasons -- or just a way to maximize profits even more.

        Don't know how accurate this is, but I've read several articles that say drug companies base prices on (a) what profits the R&D money would have generated if it had simply

    • Why did Pharma Dude Skrelli go to jail and these guys not?
      • Why did Pharma Dude Skrelli go to jail and these guys not?

        Presumably, what they've done (so far) is legal. What Martin Shkreli did wasn't. From wikipedia [wikipedia.org]:

        In 2017, Shkreli was convicted in federal court on two counts of securities fraud and one count of conspiracy.

        "Shkreli essentially ran his company like a Ponzi scheme where he used each subsequent company to pay off defrauded investors from the prior company."

        And, he's, apparently, a dick.

    • why? (Score:2, Insightful)

      by Anonymous Coward
      The better question is why are for-profit insurance companies even involved in healthcare?
    • Re:Defence? (Score:5, Interesting)

      by fuzzyfuzzyfungus ( 1223518 ) on Saturday January 18, 2025 @04:25PM (#65099483) Journal
      It's a strategy in multiple parts; and one that normally avoids walking directly into unwinnable fights (these guys are evil; but they aren't stupid and are in a position where the margins are good enough to allow for a quite sophisticated apparatus that justifies its costs by preserving and juicing the margins):

      What you will see provided openly are fairly vague, high-level, defenses of drug costs being high: lifesaving innovation isn't cheap, look at how far we've come in outcomes for X disease in the last Y years, biologics are so much more complex than traditional small molecule synthesis stuff so you can't treat generics as equivalents, etc. etc. These arguments will rarely be overtly false; though they'll be careful to avoid getting dragged into the weeds on off-message questions like "sure, that's all well and good; but how are all the same things true at less than half the price over in western europe?".

      Then there's the class of arguments that they don't exactly buy advertising for, because they don't focus-group very well, but which are made more or less openly, though usually in specialized company like investor calls, and based on actual pricing data: this is where you'll get the "Our gene therapy for Ghastly Y-Linked Genetic Disease X will be $1.5 million; because current standard of care is over $100k/year in esoteric recombinant immunoglobulins delivered in impatient infusions; so really it's a win-win". This sort of argument will studiously ignore any questions of whether esoteric recombinant immunoglobulins actually need to cost so much as out of scope; and will treat the development and production cost of cool new gene therapy as irrelevant; the price is purely a question of what the market will bear based on what alternative therapies currently cost.

      Then you get down to things like the PBM markup stuff described here; where you simply don't justify or defend the markups; but you structure the various contractual and ownership arrangements and the publicly visible price signals such that you don't have to. In some cases this is done through sheer complexity: Unless the guy at the pharmacy counter happens to be a sick investigative reporter who does a very specific flavor of story the odds are basically zero that they know anything useful about the web of ownership and contracts between the pharmacy, the PBM, the insurance company, the drug manufacturer and distributor, etc.

      Then you've got the other sense of "defend": "gag clauses". You don't have to present a principled justification of something in order to defend it; you can simply conceal or impose it. If the pharmacy can get a drug for $30; but the PBM price is over $2k; it's often cheaper for the patient to just exchange money for goods and services as though they actually lived in a free market economy and pay $30+whatever it costs to keep the lights on at the pharmacy; rather than "the drug cost $2,200; your insurance saved you $1,800; that'll be $400". So you contractually forbid the pharmacist from mentioning that option.

      In general, though, it's best not to think of American drug prices as being 'defended' in the sense of a thesis or an argument being 'defended'; but in the sense of a fortified position being 'defended': there will be some deliberately-visible arguments advanced, just as the military force that occupies a defended position will generally have a PR-friendly reason for their presence there; but the actual defense is not an argument; it's a complex and carefully constructed collection of mutually supporting camouflage, entanglements, information asymmetry, and so on.
      • by ukoda ( 537183 )
        To my mind in this case the most indefensible part is these are middlemen. They added nothing of value to the product, they brought it, marked it up and sold it. There was no innovation, no R&D and little legal risk.
    • the usa pays for the rest of the world to have capped costs

      • by ukoda ( 537183 )
        Really? I call bullshit on that statement. Care to back that up with facts from a credible unbias source?
    • ... defend such mark-ups?

      It stops the US government using market leverage against helpless billionaires.

    • They're taught that the government doing literally anything is bad.

  • by will4 ( 7250692 ) on Saturday January 18, 2025 @01:54PM (#65099183)

    Are third party payers somehow related to cost escalation?

    https://en.wikipedia.org/wiki/... [wikipedia.org]

    The phrase "perverse incentive" is often used in economics to describe an incentive structure with undesirable results, particularly when those effects are unexpected and contrary to the intentions of its designers.[1]
    The Indian cobra

    The results of a perverse incentive scheme are also sometimes called cobra effects, where people are incentivized to make a problem worse. This name was coined by economist Horst Siebert based on an anecdote taken from the British Raj.[2][3] The British government, concerned about the number of venomous cobras in Delhi, offered a bounty for every dead cobra. Initially, this was a successful strategy; large numbers of snakes were killed for the reward. Eventually, however, people began to breed cobras for the income. When the government became aware of this, the reward program was scrapped. The cobra breeders set their snakes free, leading to an overall increase in the wild cobra population.[4][5]

  • by localroger ( 258128 ) on Saturday January 18, 2025 @01:55PM (#65099185) Homepage
    The problem with drugs like sildenafil and tadalafil is that even though the street price has settled out to about USD$3 per dose (going by grey market pharmacy ads at least) the pharmacies still want their sweet, sweet, d!ck pill money and their pricing as computed by Pfizer back in the 90's when the question for their actuaries was "how much will guys let us screw them for to get these things." The answer to that was $25 per boner, more than that not enough guys can afford it and less than that they're leaving sweet d!ck pill money on the table. So even though those drugs are very useful for cardiovascular problems -- it's what sildenafil was being studied for when its other interesting side effect was noted -- you will never, ever get a pharmacy to admit that's what you really need them for.
  • I currently have Cigna coverage, and they keep pinging me to switch a prescription from my local pharmacy to Express Scripts.

    No thanks. I can smell your money-lust, Cigna. Also my local pharmacist does a fine job for me, and the prescription is not expensive.
  • They're jacking up the prices on INSURANCE, mainly Medicare, which pays the price because that's what it was negotiated at and what the great majority of pharmaceutical users are on. The patients not on insurance or medicare? Well they got hung out to dry because they don't have a "sugar daddy".

    The medical industry is absolutely not a "free market" at all. I was trying to go to a mom and pop pharmacy (they still exist) because they could get some decent prices on some of my drugs. But my insurance provi

  • Is that the correct word? Seems like an extra letter was added.

  • by MpVpRb ( 1423381 ) on Saturday January 18, 2025 @02:32PM (#65099259)

    ...voted to make it worse

    • Imagine if there had been a candidate promising to get rid of health insurance. Even better if it were a credible promise. All kinds of people would have come out of the woodwork and turned out the vote.

      As it was, neither the con artist nor the diversity hire presented a particularly compelling or credible vision. Normal and/or rational people dipped out of the voting booth, while extremists and weirdos kept on casting ballots.

  • by fahrbot-bot ( 874524 ) on Saturday January 18, 2025 @02:41PM (#65099285)

    Interactive, time-lapse chart showing Life expectancy vs. health expenditure [ourworldindata.org] by country from 1970 to 2022.
    The U.S. is an outlier -- and not in a good way...

    • But we're #1! /s

    • by dskoll ( 99328 )

      Interesting chart. The problem is that a critical mass of Americans think they cannot possibly learn anything from any other country on Earth, not to mention the fact that there are very wealthy and powerful forces who aren't interested in stopping the gravy-train that results from the fscked-up US healthcare system.

      • by dargaud ( 518470 )
        Every country should have a "ministry of finding out what is better in other countries" that suggests laws based on their findings. Europe works a little bit like that now, but not enough. As for the US, LOL !
        • Every country should have a "ministry of finding out what is better in other countries" that suggests laws based on their findings. Europe works a little bit like that now, but not enough. As for the US, LOL !

          The U.S.actually has panels for that sort of stuff for Medicare and the ACA, to review procedures and medications for effectiveness and outcomes, but no one wants to listen to them. Those on the Right cry "Death Panels" etc ... and whinge about "unelected officials" limiting medical care ... I suspect it's more about keeping the "gravy train" GP mentioned going than anything else.

  • I’m from Australia where, like the rest of the western world, you normally go to a hospital for free emergency treatment which is funded from general tax revenue and in Australia’s case a small additional tax for higher income workers. Employers do not have to fund workers healthcare.
    But I find Americans are almost universally against this. I think USA MIC has spent a lot of effort on psyoping Americans to believe it’s Communism , or unfair to subsidise unhealthy people.
    The Australian gove

  • I needed an unimaginative steroid cream for a skin condition. My insurance uses CVS as a PBM - which means that I could ONLY go to CVS to get it. My co-pay was $250 per 60g tube with insurance. So I asked - how much would it cost if I didn't have insurance? $230 without insurance, sir. So I looked around, and checked Costco - $20 per 60g tube.

    My employer chose CVS as their PBM because their bid for covering the employees was the lowest. I had no choice in the matter. Unlike most forms of insurance,

  • ... last words of an institution.
  • I have Medicare Part D insurance and don't use it. Instead, I use Amazon Pharmacy or Mark Cuban's Cost Plus Drugs. Most of their generic prescriptions are five dollars. No need to use insurance in most cases and if insurance is cheaper, Amazon will use it automatically for you in their price suggestions.

  • Americans spent $4.9 trillion on medical spending in 2023:

    https://www.cms.gov/data-resea... [cms.gov]

    $7.3 billion in price hikes over five years is a drop in the bucket. Even if we managed to regulate away that behavior, there's a lot more work to do to tame medical expenditures in the United States.

The road to ruin is always in good repair, and the travellers pay the expense of it. -- Josh Billings

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