Bird Flu Fears Stoke the Race for an mRNA Flu Vaccine 236
Concern over potential human-to-human transmission of bird flu has risen after six Missouri healthcare workers developed mild respiratory symptoms following contact with a patient infected with H5N1. The CDC reports only the original patient has tested positive for the virus. Scientists are ramping up efforts to develop mRNA vaccines against H5N1, with researchers at the University of Pennsylvania and major pharmaceutical companies like Moderna, Pfizer, and GSK leading the charge. While mRNA technology offers rapid vaccine production, clinical trials have shown mixed results, particularly against influenza B strains. Wired adds: [...] Traditionally, flu vaccines contain inactivated viruses that are grown in hens' eggs. This works reasonably well, but it takes a long time to make such jabs, which means health authorities have to publish their predictions about which strains of flu will be circulating during the upcoming winter well in advance. If you could manufacture vaccines more quickly, you could make more accurate predictions nearer to flu season.
Not only that, researchers hope that a single mRNA shot could one day target 20 or more strains of flu at once, relieving the need for some of this guesswork. Scher's colleagues are working on such a "universal" flu vaccine. With clinical trials ongoing, it's still early days. Sheena Cruickshank, an immunologist at the University of Manchester, has watched reports about emerging mRNA flu jabs with interest but says that questions remain. "We don't yet know how long-lasting the immunity they produce is," she says. Michael Osterholm, director of the Center for Infectious Disease Research and Policy at the University of Minnesota, concurs, though he notes that all flu jabs, regardless of how they are made, have a waning immunity problem -- your protection could decline by around 10 percent every month following injection.
Not only that, researchers hope that a single mRNA shot could one day target 20 or more strains of flu at once, relieving the need for some of this guesswork. Scher's colleagues are working on such a "universal" flu vaccine. With clinical trials ongoing, it's still early days. Sheena Cruickshank, an immunologist at the University of Manchester, has watched reports about emerging mRNA flu jabs with interest but says that questions remain. "We don't yet know how long-lasting the immunity they produce is," she says. Michael Osterholm, director of the Center for Infectious Disease Research and Policy at the University of Minnesota, concurs, though he notes that all flu jabs, regardless of how they are made, have a waning immunity problem -- your protection could decline by around 10 percent every month following injection.
Jumps to mammals ... (Score:2)
The current strain of H5N1 jumps to mammals regularly.
For example, dozens of tigers died in Vietnam [msn.com], and before that seals in Patagonia [apnews.com].
It is only a matter of time before it infects humans in significant numbers.
Oh, and by the way, this is zoonosis at work, no lab leak crappy hypothesis...
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The FBI director's analysis and opinion is contradicted by a multitude of virologists, and epidemiologists and published scientific papers, which all point to a zoonotic origin. So it has little weight, if any.
Hereisthe most recent paper, analyzing DNA samples from a specific corner in the Wuhan market [msn.com].
Giving testing, would mRNA vaccine be quicker? (Score:2)
Sure, developing the new vaccine is faster but the long pole seems to be testing. That is why COVID vaccines and boosters are based on the strains circulating the previous winter. The 2022 version was available in September based on variants circulating in July. It was really cool because it was the only time most of us had access to a vaccine based on the currently circulating strain. However, they achieved this by going directly from animal testing to shipping product. No human testing. That was app
Most people not vaccinated (Score:2)
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No thanks (Score:2)
So, everyone who was pro vaccine mandate ( and many even went full Nazi with deny those people healthcare, put em in quarantine camps and let them die ) loved to parrot the phrase " Follow the Science " during the entire event.
Which I find amusing as hell because, what they really meant was, " Only follow the Science that we approve of and ignore everything else. "
To wit:
THE SCIENCE says, the vaccine development timeline usually takes around 5 - 10 years to go through all the trials, ensure its safety and d
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So, everyone who was pro vaccine mandate ( and many even went full Nazi with deny those people healthcare, put em in quarantine camps and let them die ) loved to parrot the phrase " Follow the Science " during the entire event.
Which I find amusing as hell because, what they really meant was, " Only follow the Science that we approve of and ignore everything else. "
To wit:
THE SCIENCE says, the vaccine development timeline usually takes around 5 - 10 years to go through all the trials, ensure its safety and do the whole regulatory process to do as much as possible to ensure the safety of the product in question. But, those who pushed the Covid-19 vaccine just flat out ignored -THAT- science and elected to cut some corners in an effort to be seen as " doing something ".
You all want to line up and be a guinea pig, be my guest. But don't drag the rest of the World into your insanity along with you.
Why would Donald Trump do such a thing? https://trumpwhitehouse.archiv... [archives.gov]
Big Pharma stoke fears to sell product (Score:2)
mRNA: the truth about this is finally being reveal (Score:2)
Re:Don't believe the hype (Score:5, Insightful)
https://en.wikipedia.org/wiki/COVID-19_pandemic_death_rates_by_country [wikipedia.org]
https://www.cdc.gov/flu/vaccines/keyfacts.html [cdc.gov]
Logic of the insane "Companies only want to get richer off this!" meanwhile "privatize schools!" and "private companies should do this work!" (hint: you should look at the cost difference)
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You're comparing primary education and mRNA vaccine development. Impressive.
Stupid, but impressive. If privatizing education is bad, why is privatizing medicine NOT...? Oh, cause the government does such a great job.
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Re: Don't believe the hype (Score:2)
Nature also gives no indication any of the 6 workers had bird flu as all their tests for it came back negative.
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Re: Don't believe the hype (Score:5, Informative)
Except in Japan which had a very low transmission rate before the Covid shots were released
That's because Japanese people readily wear masks when they're sick to prevent others from getting sick. For them, putting on a mask to prevent getting sick is second nature.
Unlike in the U.S. where it was the most difficult thing in the world to do.
Re: Don't believe the hype (Score:4, Informative)
I am still amazed at how many people, even in my own entourage, keep on insisting that masks are a PPE (with the corollary that it does not work as PPE) and not source control.
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Unlike in the U.S. where it was the most difficult thing in the world to do.
Unless you're in the KKK or white supremacists. https://www.wgal.com/article/h... [wgal.com]
Oh and spare me the "they're feds" bullshit. Which federal agency is this? Why would they cosplay as nazis, to make the right wing look bad? The right wing certainly doesn't need any help there. https://www.npr.org/2024/09/10... [npr.org]
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Cool, cool.... so in that same vein, you must also have that level of education to understand it.
Tell me Dr. "ihavesaxwithcollies", what is your clearly level headed and scientific belief in this?
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The covid vaccine is one of the most tested and closely studied vaccines in history. Plus mRNA has was discovered in the 60s and research started in the 90s. https://publichealth.jhu.edu/2... [jhu.edu]
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Did you ride this bus to school? https://marktindle.com/2015/11... [marktindle.com]
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Who modded you up?
I did. (Only astute Slashdotters will find this funny.)
Re:Don't believe the hype (Score:5, Informative)
What fiasco? The vaccine has been proven effective [cdc.gov] and has saved many lives.
Are you talking about the sensationalist headlines that made it sound like the vaccine killed more people than it saved, when in fact (if you read the articles that had those headlines) they said the exact opposite? They used clever wording and statplay to creating a shocking headline that simply didn't mean what it seemed to mean.
Or maybe those predictions of a mass die-off two years after getting the vaccines, which turned out to be pure bunk and didn't happen at all?
Or the ridiculous claims of microchips in the vaccines?
Or something else I am not thinking of?
Re: Don't believe the hype (Score:2)
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The most successful vaccines there are -- measles vaccines -- don't prevent the spread of measles in the sense you are apparently using the word. They reduce the spread enough so we can go about our business.
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There's a functional difference. With a perfect vaccine you wouldn't worry about exposing yourself to an infectious case of measles. With the actual vaccine, you should avoid that contact and use precautions like mask if you can't because you don't have 100% certain immunity. The reason you won't get *fucking Measles* as you put it with the actual vaccine is a combination of two factors -- a *probability* you are immune and the *improbability* of being exposed to measles because of herd immunity.
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Your response suggests that you really aren't thinking this through. You seem to lack the most basic understanding of how vaccines work, and the benefit they provide.
They are what we call an "imperfect solution." They aren't a cure. They don't completely halt the spread of a disease in its tracks. But they do slow its spread, prevent a percentage of people from ever getting the disease, and reduce the symptoms for those who wind up getting the disease anyway. These benefits are more than worth the mild
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Why would Donald Trump do such a thing? https://trumpwhitehouse.archiv... [archives.gov]
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can't believe someone will take any vaccine after the covid fiasco
I can't believe that the CIA and NSA haven't rooted out and jailed or killed you FSB agents sent to the U.S. to cause chaos.
Re:The motivation is profit (Score:5, Interesting)
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How dare companies try to find a way so people don't get sick or die. The outrage! We should let nature take its course and have tens of millions die [wikipedia.org] from a simple cold. Right now only about 50,000 people die each year, let's crank those numbers up and really drive the economy into a tailspin.
Umm, I think you have it backwards. Companies are in the game to make money. The pharma industry literally makes money from you being sick Seriously, take the rose tinted glasses off and have another look around.
Re:The motivation is profit (Score:5, Funny)
The pharma industry literally makes money from you being sick
And farmers earn money from you being hungry. IT'S A CONSPIRACY!!!! Farmers are making people hungry!
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Re:The motivation is profit (Score:5, Informative)
Dr. Malone's statements have been thoroughly debunked [factcheck.org] by the ultimate authority of all scientific discussions: evidence.
That's the kicker. He offered his statements without any evidence at all, and couldn't supply any later when asked for some. And, as it turns out, evidence was available, and it flatly refuted his claims.
Your statement is a good example of fallacious reasoning. You believed his claims were true because of who he was. His degrees and other accomplishments. But such facts about the speaker do not make the claims true. One needs evidence of the claims themselves. This is precisely what separates science from religion.
You subscribe to the anti-vax religion. Rather than looking at evidence and drawing your conclusions from that, you search for people who say what you have already concluded to be true. Then you drop their names and act like you have proven your point. In fact, this proves only that you aren't being objective, and aren't basing your conclusions on evidence.
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No, I have data and evidence, which I linked. Malone has no data or evidence at all, and neither do you.
Clearly, you also don't have the ability to understand why this is critical, and makes a difference.
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Why does th
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But flu shots *are* vaccines. It's never been the case that most vaccines give lifetime immunity; the ones that do are actually a rarity. We're just more familiar with the lifetime vaccines (MMR, DTaP, etc.) because everyone gets them as a kid.
This isn't rocket science. The difference between a lifetime immunity vaccine and one that you need to get regularly is the viruses. Viruses that have capsids (protein coats) that are genetically stable over decades can have one-and-done immunizations. Viruses where
Re:Betting pool on (Score:5, Interesting)
#1 is the fault of a conservative media that revels in giving life to things like 5G conspriracies, they own that one.
How fast the democrats will push to make it a mandatory condition of stepping outside your door.
Yeah ok, conservatives from small folks to right to the largest media figures told us for what, a year or two, that Federal mandates would be a thing and how any day now, how it didn't work and how there would an upcoming wave of side effects all the way to mass death.
None of this happened and they get to just brush past it and pretend they never said all those things with conviction, so are they just dangerously misinformed or were they lying? I think there should be some admission of "we got all that wrong and we are very sorry" before we go ahead abd believe anythign they have to say again.
Re: Betting pool on (Score:5, Interesting)
But they did get to limit what drugs women can put in their body. So partial win??
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Nah, the victim card doesn't work anymore, conservatives have milked that long enough.
The largest alterantive media influencers, channels, podcasts with viewbases in the millions and millions and their continued dominance of local news and talk radio means I don't have to listen to what MSNBC is saying, you can throw a rock and hit a piece of conservative media.
No more hiding behind the "mainstream media" charade like they are some oppressed counterculture, conservatives speak for themselves, loud and clear
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Before I explain, I have to ask, as a libertarian, who are you voting for?
As we famously know there are many types, it's kinda their whole deal.
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Lol, welp, I don't have to change my opinions on libertarians then (as a former literal card carrying LP member)
Pretty sad to see where it's at
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Any Libertarian who isn't gritting their teeth and voting for Harris because we have the most anti-constitutionlist candidate in our lifetimes as the other side doesn't deserve debate is really my point.
Just say you dislike liberals more than you actually care about "constitutionality"
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nah, libertarians had their best shot in 2016 and blew it, then they had trump at their fucking convention. the greens are still worse, but not by much anymore. see you for the next 4 year drive by without getting anything done.
if youre sitting here in 2024 and still thinking both parties the same like it's 2004 and edgy again you either don't actually give a shit and aren't paying attention or you are just a conservative too embrassaed to say it. whats the funny part is this outlook is almost carbon boped
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Think what you want but my point is you can say all you want about what you believe but you are very quick to sell it out to own them libs right?
You and the other both-sidesing fence sitters out there just have lost the plot. Once again, do you really think "both parties are the same" in 2024, after 4 years of Trump as president, his attempt to overthrow the election (which don't even say Jan 6, it was much longer and a more involved plot than that as we just saw in the indictment a couple days ago) and co
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Libertarians are just republicans that don't want to pay taxes.
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We do not need to, we get a very good dose of both extremists sides here on slashdot.
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Try to learn one day the difference between "what conservative media are saying" and "what MSNBC says conservative media are saying". The world will suddenly make a lot more sense, I promise.
Trump verbatim from the debate. https://abcnews.go.com/Politic... [go.com]
In Springfield, they're eating the dogs. The people that came in. They're eating the cats. They're eating -- they're eating the pets of the people that live there. And this is what's happening in our country.
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Russell's teapot [wikipedia.org]
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I asked first.
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I didn't say "you" said those things, I said conservatives and more specifically their media said those things.
This was mainstream stuff, I was alive 2020-2022, RFK, one of the most notable antivax people is a top advisor to the Republican candidate. This is not extreme anymore.
The mass death death thing like all the conservative conspiracy stuff (your qanons for example) just gets mindwaved away into the now more reasonable position and we all forget about that other stuff that never happened.
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Yes, conservatives are the current enemy of America. I responded to a guy with the words right wing in his handle, you're hear defeing conservatives and de facto trump even if you don't say it.
I'm saying what needs to be said and their pearl clutching doesn't mean anything anymore.
A literal anti-american party draped in performative patriotism.
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Sure I am, we should be fighting them all the time as true patriots. They're all over this thread, you included.
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nah we're taking the word liberal back baby, because thats what it is. some of us believe in the concept of liberalism, some people don't anymore. i think that's bad, it's been pretty good.
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Specifics are for when we have 2 parties that actually believe in the concept of liberalism but right now we have a party of illiberalism which is too dangerous to split hairs over specifics. You don't thik or care about that so why should owe you specifics.
Liberalism is a political and moral philosophy based on the rights of the individual, liberty, consent of the governed, political equality, right to private property and equality before the law. Liberals espouse various and often mutually warring views
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Also here you, I forgot that in pursuit of this fruitless question of category which I can't really answer because it's a bit of all of them like all people, but here's my domestic policy in a nutshell:
Second Bill of Rights [wikipedia.org]
Re:Betting pool on (Score:5, Funny)
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4. How fast the GOP will organise "flu parties."
Not 'troll'.
If the Marburg virus or Ebola virus started having human cases of them in the U.S., they'd have 'parties' to infect each other with those, too; call it 'evolution in action ' -- which is ironic as fuck, since most of them are 'creationists'.
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Oh that's right you're probably not even an U.S. citizen, just some asshole Russki getting a paid in Rubles.
Or if not then you're just a Useful Idiot for criminal rapist-traitors like Trump and the Fascist Pig Party (formerly known as 'Republicans').
Get medicated, your head is sick.
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& yeah, I'll take the advice of virologists, epidemiologists, & other relevant experts in their fields over some attention-seeking politician or random dude who's "got a theory" on Youtube, any day.
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Re:Betting pool on (Score:5, Informative)
2. How fast the democrats will push to make it a mandatory condition of stepping outside your door.
Do you have children in public schools? You must provide proof of vaccination before children can be enrolled. Nearly every employer in the medical field has vaccine requirements for employees. When you let religious nutjobs skip vaccines you get outbreaks, like this for example. https://www.nyc.gov/assets/doh... [nyc.gov]
Hell in 2000 the CDC declared measles eliminated, thanks to vaccines of course. https://www.cdc.gov/measles/ab... [cdc.gov]
Re: Betting pool on (Score:2)
I do. And get ready to have your mind blown: they get their shots on time and on schedule. The exception to that is, like something like 3/4 of parents even in the blue districts, I didn't bother getting them covid shots given they all got covid (ranging from no symptoms to standard kid cold) before kiddie shots (with their mind-blowing 20-30% claimed efficacy) became available.
If I were to have another newborn now, maybe a covid shot would be in the cards. But not because some didshit at the CDC who flunke
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You're comparing two very different kinds of viruses. Traditional flu shots are only 40-60% effective on a given year because they rapidly mutate like coronaviruses do. They are still highly recommended. Even if you don't prevent illness, you reduce transmission. And even when there is transmission, you reduce severity.
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You think it's related to the type of vaccine but it's really about the virus. Don't forget that there were non-mRNA vaccines also.
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Yeah, there's no basis to think that and I've already explained why it's not a good conclusion. So you can just think things on a whim if you want but you can't act like it's supported by anything.
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Tell me why mRNA is bad.
Re: Betting pool on (Score:2)
Cuz the gay frog chemtrailz. Duh.
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Tell me why mRNA is bad.
Trick question, because it's not.
Fucking hell, mRNA is making breakthroughs in CANCER RESEARCH.
But the fucktard Fascist Pig supporters don't care, do they, they think that Zombie Jesus will only give liberals cancer, and these fucktards will somehow be magically immune. How fucking stupid are they?
Re: Betting pool on (Score:2)
Go out and meet some people.
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mRNA technology has been around for around 50 years [jhu.edu], longer than you've been on this planet. It's been used in multiple applications [nih.gov] during that time.
Now go collect your vodka or however you're being paid seeing how Russian companies have to resort to bartering [newsweek.com] because they don't have the money.
Interesting (Score:2, Interesting)
1. You point to a dubious source that shoveled mountains of lies on the subject for YEARS (the NIH) to make a claim that mRNA tech has been around for 50 years... but THAT'S NOT WHAT THAT WEB SITE SAYS. Even the NIH admits that while the subject has been STUDIED for many years, "Phase 1 clinical trials to test the safety of mRNA vaccines for Nipah virus; the trials began in 2022" and the rest of that page goes on and on about the [failed] COVID-19 vaccine.
Why do I say "failed" COVID-19 vaccine?
Remember when
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Remember when ALL the health "experts" of our government and the politicians in BOTH parties were asserting that people who got vaccinated would not get COVID? Remember when these people further beclowned themselves claiming vaccinated people would not spread the illness? Remember when they claimed it was a pandemic of the unvaccinated? That the first booster would work? the second booster? At this point, we know that mRNA vaccines for COVID-19 do NOT prevent you from getting the illness, and do NOT prevent you from spreading it... so there's really no point to them. In addition, most people know somebody who was harmed by them - something NOT true of most other [traditional] actual vaccines. Actual traditional vaccines, like for polio, mumps, smallpox, tetnus, all really work - people vaccinated do not get and spread these illnesses [the core actual criteria for whether a vaccine is "good"].
Look mRNA vaccines were a great, geeky, idea for a new way to mass-produce a vaccine in a hurry for any new illness without having to use chicken eggs. This would be great for responsiveness to new illnesses, great for people with egg allergies, great for quality control, etc. Unfortunately, the tech appears to have been launched prematurely before it was fully-understood. The developers could not get a broad trial approved, but then came the scary pandemic from Wuhan and all the usual safety barriers were dropped - a new vaccine tech was deployed without ANY of the usual safety and efficacy testing. In effect, the manufacturers got to use the entire planet's population as a pool of test subjects.
2. What the hell does Russians bartering with people like the Chinese to avoid western sanctions have to do with mRNA vaccines?
If what you said is true, how do you account for this?
https://health.ucdavis.edu/new... [ucdavis.edu]
https://www.ncbi.nlm.nih.gov/p... [nih.gov]
https://www.heraldnet.com/news... [heraldnet.com]
https://triblive.com/local/wes... [triblive.com]
Relevant bit from the last one. For those who are hospitalized with covid, 93% were not vaccinated. And every single covid patient on a ventilator had not gotten the immunization, she said.
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Re: Just Say No to mRNA (Score:2)
Like the time you took wild guesses in slashdot comments? I guess rules for thee but not for me. You must have been the hit of parties during the plandemic
Re: Just Say No to mRNA (Score:2)
Related link: https://m.slashdot.org/thread/64835783
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Congress shall make no law respecting an establishment of religion, or prohibiting the free exercise thereof; or abridging the freedom of speech, or of the press; or the right of the people peaceably to assemble, and to petition the Government for a redress of grievances.
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Telling an idiot to stop talking is not abusing your freedom of speech.
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Stop posting and fix your brain, you're embarassing yourself.
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Lots of vaccines don't provide total lifetime protection. You should get a tetanus booster every 10-years, rabies vaccines last a couple years, flu shots, etc.
Ten seconds of consideration might lead to you realizing you can catch a cold a couple times a year, but chicken pox will only infect you once. Its almost like the immune system doesn't behave the same way with every infection....
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Settle down grandpa. It's time for Wheel of Fortune and a mug of sleepy time tea.
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Learn2biology, you dumb shit.
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If you're worried about SV-40 today, then you didn't read carefully enough. That was contaminated polio vaccines from at least 60 years ago and really nothing to do with the vaccines themselves. Pretty sure they're gone now.
Re: Hypochondriacs Anonymous! (Score:2)
Why do you NPCs keep saying this? The pandemic has been over for two and half years. The vast majority of humanity is not getting COVID boosters any more, the NWO didn't take over the world, billions didn't die from the vaccine, senior Democrats are not abusing children in the basement of a pizza restaurant without a basement and Donald Trump is not fighting the deep state from his golf course.
About the only thing you lot might have got right was that someone fucked up in a disease lab and a lot of arse c