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Science News

Rivers Becoming 'Reservoirs of Disease' (bbc.com) 54

Scientists say "a reservoir of disease" is being created after discovering bacteria that naturally occur in rivers are becoming resistant to antibiotics due to the impact of sewage. From a report: Researchers at the University of Suffolk said bacterial strains found on the non-tidal section of the River Deben in Suffolk had acquired resistance by exchanging DNA with antibiotic resistant E. coli. Some bacteria have become resistant to the antibiotic carbapenem, which is used as the last line of defence in fighting infections already resistant to traditional antibiotics. Dr Nick Tucker, a microbiologist leading the research, described the discovery as "particularly worrying."

"Organisms that are currently low risk are being mixed with pathogenic organisms from sewage," he said. "We're needlessly adding pathogenic and virulence genes to bacteria found in the environment, and that could be creating a reservoir of disease." The team has been working closely with citizen scientists from the Deben Climate Centre, who have been taking water samples for two years. They have also been working with scientists at the government's CEFAS laboratories, who have helped identify the new strains that are being screened for their resistance to six of the most commonly-used antibiotics. The River Deben rises in Debenham, Suffolk, before flowing through Woodbridge and down to the North Sea.

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Rivers Becoming 'Reservoirs of Disease'

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  • by account_deleted ( 4530225 ) on Friday July 12, 2024 @02:27PM (#64621883)
    Comment removed based on user account deletion
    • by Archtech ( 159117 ) on Friday July 12, 2024 @02:46PM (#64621919)

      A fairly broad clue should have been offered by the fact that almost all antibiotics were originally copied from organisms which evolved the ability to make them in self-defence.

      If bacteria and fungi have been waging biological warfare on the largest scale for hundreds of millions of years - as they have - it should have been utterly predictable that they would mostly also have evolved defences against antibiotics. Otherwise they would have been wiped out millions of years ago.

      Humans have clumsily blundered into the ongoing biological war, and unsurprisingly have turned out to be completely outgunned. However our greatest liability has been our inability to organise and to act in our own self-interest as a species. Corporations and even individuals have for decades been spewing vast tonnages of antibiotics into the environment - a formula for creating resistance that could not have been bettered if it had been deliberate, which governments appear quite helpless to stop or even to reduce.

      • https://en.wikipedia.org/wiki/... [wikipedia.org]
        "Phage therapy, viral phage therapy, or phagotherapy is the therapeutic use of bacteriophages for the treatment of pathogenic bacterial infections. This therapeutic approach emerged at the beginning of the 20th century but was progressively replaced by the use of antibiotics in most parts of the world after the Second World War. Bacteriophages, known as phages, are a form of virus that attach to bacterial cells and inject their genome into the cell. The bacteria's production

    • life finds a way. these microorganisims are life, they are finding a way to survive. that is what life does. When i was a young sprog in my first biology class they taught us that E. Coli was no threat because it couldn't survive in the open, the uv light from the sun would kill it.

      E. Coli, heard that and said, "Oh, Yeah? Hold my beer..." and now we have E. Coli happily living in waterways that people bath in and drink from.

      When I was a teen, mountain climbing in Colorado, unless there were sheep in th

      • by Sique ( 173459 )
        It does not need to be E.coli in the open. E.coli in the sewer, far away from any UV, horizontally exchanges genes with another strain of bacteria, which can survive in the open at least for a considerable amount of time, and this one then does another horizontal gene transfer with bacteria living downstream in rivers close to the sea.
        • yep, that was just an example, here in teh good ol' USA we have E. Coli in some rivers, lakes and ponds, but as I said, that was just an example.
          • by Vlad_the_Inhaler ( 32958 ) on Friday July 12, 2024 @03:45PM (#64622035)

            Well that example - the River Deben - is from England and the UK has its own major problems with sewage.
            Up until around 1970, local authorities were responsible for organising the supply and subsequent recycling of drinking water. Unsurprisingly, some areas did a better job of it than others. Then Ted Heath's government (I think) created regional "water boards" to handle the problem at a higher level, I'm not sure how well that worked - they may well have been starved of investment - because Margaret Thatcher's government privatised the water boards. These private companies have been very good at paying dividends to their owners while amassing debts but have done a very poor job of disposing of sewage.
            As with everything else, these companies have targets they have to meet. It turns out that one effective way of meeting those targets is to dispose a significant proportion of the untreated sewage into the rivers. This is being practised on a massive scale and was one of the reasons the previous government performed so catastrophically in the election last week - they were the party responsible for the current failing system.
            One major sporting occasion every year is the University Boat Race between Oxford and Cambridge. Normally the winning team jumps into the river to celebrate, this year they were warned not to do that - the E Coli values made that just too hazardous.

            • Just to correct you slightly, in most cases the discharges to rivers are from storm overflows that operate when the (ancient) sewerage infrastructure is overwhelmed. Rather than flood properties, the sewers discharge the (diluted) sewage into a watercourse. All of these overflow points are permitted by the regulator and to upgrade the system would cost billions to billpayers.... the reason it wasn't done before? Massive under-investment as usual and people acting surprised when things don't last forever!
      • More than that, just from a layman's knowledge of evolution theory we should have known this was coming.

        The bacterium that survives the antibiotic is the one that gets to continue reproducing, passing on the genetic trait that allowed it to survive. Enough cycles of that, and all you have left is bacteria DNA that resists the antibiotic. We came up with different antibiotics, and the bacteria is evolving to resist those too.

        I guess apparently we were awesome enough to both define and ignore a theory of ev

        • We came up with different antibiotics, and the bacteria is evolving to resist those too.

          True, but bacteria have a very small genome and given time, they won't be able to add resistance to something new without it replacing resisting something that's old enough that it's not in the environment any more, or at least not enough for it to pay the bacteria to hang onto that resistance any longer. When that starts happening, we can start using some of the older drugs again because bacteria have "forgotten" ho
        • Well, yeah, it seems we are really good at ignoring stuff we don't want to see.

          I still envy you your machine shed, Fred.

    • by hey! ( 33014 )

      In this case you're missing an important part of the story: it's happening in UK rivers that have been polluted by dumping waste.

      Evolution doesn't target us; it doesn't notice we're not getting sick and then go out and engineer a new bug. Evolution adapts the descendants of an organism to the environment in which they find themselves. It's the actions of humans, dumping waste containing both human pathogens and drugs into waterways that converts those waterways into evolutionary bioreactors.

    • Yes, I know - evolution hates to be anthropomorphized

      Nah, it's all good, a friend of mine went to school with her and she's fine with it. But you're right, she can be a pushy bitch at times.

  • Good (Score:1, Troll)

    by zenlessyank ( 748553 )

    A society dumb enough to dump sewage into a river deserves everything they get. Or building a factory next to a river then wondering why the water is poison.

    I have lost all hope for mankind. Hopefully Jesus got wise and decided to never come back. Fuck humans.

    • 100%. This. And politicians in thrall to their corporate masters want to repeal any legal protections us little people have from this type of behavior. Yay, destroy the EPA! Rather than, hey, hold the damn EPA (the individuals in the EPA that made the decision to not do their job, really) accountable when they don't enforce the regulations as an example.
      • Well the EPA is still around, I'm sure you've heard. Let me know when I can stop holding my breath for them to be held accountable. The idea that the government can create regulatory bodies and that they totally won't get captured or controlled by the interests they regulate has been thoroghly disproven, just going off the results they've failed to generate. Regulations and regulators might look viable on paper, but it's got a pretty poor track record and now you got a bunch of expensive bribed freeloaders
    • Re:Good (Score:4, Informative)

      by SirSpanksALot ( 7630868 ) on Friday July 12, 2024 @02:50PM (#64621929)

      A society dumb enough to dump sewage into a river deserves everything they get.

      Erm.. That's where all sewage ends up from every society ever. It's generally "treated" in first world countries first though...

      • A society dumb enough to dump sewage into a river deserves everything they get.

        Erm.. That's where all sewage ends up from every society ever. It's generally "treated" in first world countries first though...

        Also, What do you think fish, marine life, amphibians, aquatic mammals etc. do?

        • by hey! ( 33014 )

          Also, What do you think fish, marine life, amphibians, aquatic mammals etc. do?

          The same thing land animals do. If you were a paleolithic hunter gatherer you wouldn't mind living in the woods the animals shit in. That doesn't mean you wouldn't mind living in a barn that nobody every mucks out. That is the original version of "too much of a good thing".

          The old saying in environmental engineering is "dilution is the solution to pollution". This is very true for animal waste products; if it's diluted across the animal's habitat it will recycled by bacteria into beneficial nutrients.

      • I think some countries dump them in the sea (not at the shore, they got a pipe going deeper into the sea) after treatment.

        At least I think Singapore does that. I assume at the least other small countries with sea access and with the capability are also doing that. Bigger countries / land locked countries may not be able to do that.

    • That is why Mrs Thatcher explained patiently that "there is no such thing as society". It's a useful abstraction for the ways in which we ought to behave if we were intelligent enough to act in our own interests.

      It's not "a society" that dumps sewage into a river; according to the article, it's 'multiple sources, including "domestic cesspits, farms and some industrial waste"'. In other words, a mixture of individuals and corporations unrestrained either by government or by morality. Of course, the sources o

    • A society dumb enough to dump sewage into a river deserves everything they get.

      And yet there seems to be no shortage of Indians, who ritually bathe in one of the most polluted rivers in the world, pollution that includes copious amounts of raw sewage. Filth doesn't kill Third Worlders because they haven't tried to separate themselves from it the way the First World has. The cleaner we lived, though, the more we lost our defenses against the kind of stuff that occurs naturally.

      • Long ago a colleague returned to Kolkata for what was supposed to be a 3 week family visit. He returned 6 months later, gaunt and pale, apparently having lost acquired resistance to hepatitis.
      • Religion is only here to rape the willing. Jesus didn't build a church. Being a carpenter and a direct descendant of The Creator would make you think he would have built a couple.

        Shit rolls down hill where the river flows. You really can't fix stupid, just kill it or watch it suicide out.

    • The truth is a troll. You guys are so fucked in the head. Keep voting for cocksuckers that make you suffer. Stupid fucks.

  • The anti-vaxxer/anti-medicine/anti-science crowd will bear the largest brunt of these antibiotic-resistant pathogens we've created. Just like happened during covid [yale.edu].
    • Mike Dickson is that you? Oh, wait, I guess it cannot be him because he collapsed and died right after his idiotic criticism of Novak Djokovic for his vaccine skepticism. Remember skepticism? You know, the basis for science?
      • There's a difference between scepticism and denialism.

        • It's denialism to be skeptical of a drug that was rushed out, failed to prevent transmission, and had a risk for serious side effects like Myocarditis in young healthy people like Novak? Sounds more like the apologists were in denial about it's lack of effectiveness and it's risks, not the other way around.
          • by MrNaz ( 730548 )

            Given the unprecedented level of testing, the data collected, the exigent circumstances, and the available options, yes. It's denialism. Although I don't expect you'll have the mental capacity to grok why.

            • No, Dr. Mengele was wrong and so are you. Handwaving more furiously and doubling down on more denial won't change a thing. Remember, it's after we all saw what happened and how poorly the vaccines performed not to mention how desperate the government has been to cover up their failures. That's not how you act with successful medical treatments, that's how you act when you were full of shit in the first place and turned to authoritarianism when you failed to convince anyone.
    • Really... you're thinking that the people who said "I'll take my chances and trust my immune system instead of outsourcing it to big pharma" are going to be the first to suffer when big pharma's drugs stop working?

      Wisdom is chasing you, but you are faster!

       

  • Gross.
  • by Miles_O'Toole ( 5152533 ) on Friday July 12, 2024 @04:02PM (#64622053)

    Yet another triumph for privatizing public infrastructure, then allowing one's corporate buddies to profit off it and regulate themselves.

    • Re: (Score:1, Troll)

      Good thing we have Big Brother to protect us with the EPA. They totally took care of... wait ... nevermind.
      • The EPA is part of the United States government. Those of us fortunate enough to live in civilized countries don't deal with it.

        Just out of curiosity, when you refer to "Big Brother", are you talking about that convicted felon your Republican Party is attempting to put in charge of your country, even though he has never won a popular vote, and never will?

        • You mean like the Labor Party, which now rules your country and got 33.8% of the popular vote? That's not someone rigging voting machines or printing a zillion ballots to stuff in an unattended box, that's how your system "works".
  • muy profits \ dividends!
  • by CaptainOfSpray ( 1229754 ) on Friday July 12, 2024 @04:29PM (#64622105)
    ...and my MP was (until the election) Therese Coffey, Secretary of State for Environment, Food and Rural Affairs.. She is a Chemistry PhD (UCL). For God's sake, she should have known better than to allow this to occur.

    On the other hand, we have always known that she was a party hack. Round here, we call her The Chocolate Teapot - (she is as useful as a ...).

    I am not looking forward to telling the village that we are living next to a sewer full of drug-resistant bacteria.

    This was supposed to be the last undeveloped river in England.
    • by hey! ( 33014 )

      Those rural constituencies probably aren't going to be happy if Labour cracks down on agricultural runoff.

  • Most of the time, maintaining a biological function like antibiotic resistance has a metabolic cost, hence we can hope the resistance will vanish once the bacterial will be in an antibiotic-free environment. This is just hope.
  • Raw sewage in the river? Don't you worry about that! This guy [youtube.com] will get you sorted!
  • "I'd like to share a revelation that I've had during my time here. It came to me when I tried to classify your species and I realized that you're not actually mammals. Every mammal on this planet instinctively develops a natural equilibrium with the surrounding environment but you humans do not. You move to an area and you multiply and multiply until every natural resource is consumed and the only way you can survive is to spread to another area. There is another organism on this planet that follows the sam

  • ...the UK should stop pumping raw sewage into rivers and lakes over 1000 times per day, 400,000 times a year.

Every nonzero finite dimensional inner product space has an orthonormal basis. It makes sense, when you don't think about it.

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