Kidney Transplant Patients Will Test a COVID-19 Booster Shot in New Trial (theverge.com) 34
The National Institutes of Health is giving a booster dose to 200 kidney transplant patients who did not have an immune response to the COVID-19 vaccine in a new trial that launched yesterday. From a report: Many transplant patients, who have to take immunosuppressant drugs to keep their bodies from rejecting a new organ, don't produce enough antibodies -- or don't produce antibodies at all -- after getting the COVID-19 vaccine. The study will check to see if a third shot of an mRNA vaccine, given on top of the normal two-shot regimen, will generate antibodies closer to the levels seen in healthy people.
There are some indications that a third dose might help some people. In France, health officials started recommending in April that immunosuppressed patients get a third shot of the COVID-19 vaccine. Half of the patients who did not respond to two shots produced antibodies after the third, according to an analysis of 159 kidney transplant patients. The other half, though, still had no response. In Germany, one study of 48 transplant patients found that 40 percent who didn't respond to two doses had a response after the third. Two other trials looking at kidney transplant patients are also kicking off in Israel and Switzerland.
There are some indications that a third dose might help some people. In France, health officials started recommending in April that immunosuppressed patients get a third shot of the COVID-19 vaccine. Half of the patients who did not respond to two shots produced antibodies after the third, according to an analysis of 159 kidney transplant patients. The other half, though, still had no response. In Germany, one study of 48 transplant patients found that 40 percent who didn't respond to two doses had a response after the third. Two other trials looking at kidney transplant patients are also kicking off in Israel and Switzerland.
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I get my flu shot every year. Because even getting a mild flu really sucks.
Covid is worse than the flu. With more longer term effects, and a higher chance of death. However even if I end up with the symptoms similar to a mild flu, getting a shot and its effect on me is much better than getting the mild flu like symptoms.
Sure I am tough enough to deal with a Flu symptoms if I have too. But there is no need to force myself to get sick, and then be weakend for weeks after that, just because I wanted to avo
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Seriously, this. Not to mention that one of the primary jobs of a pathogen is to not have you develop a lasting immunity to it (if any at all). With COVID, the level of immunity after infection varies greatly, from "great" to "really poor". Also, antibodies tend to target only a single epitope (E484) [sciencemag.org] - meaning that mutations in just this one epitope can evade most "natural" immunity. Vaccination by contrast involves constant doses to try to yield consistent immune responses, and does not try to hide epitop
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We need to be all vaxxed to death or else we could catch a mild flu.
You heard it here first folks, nyet to vaxxx!
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Protip: The crazier these guys are, the more x's they put in "vax."
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No, I heard it last week on the local news, some rual cluckstucker was saying that people of his "family makeup" (that's the actual term he chose to mean "Republicans") didn't think they needed to get the vaccine because it was just a "mild flu." He was speaking from the waiting area at the ICU, where his wife was fighting for her life. And then he said, "But now that's only true for people with the vaccine!" and "We didn't know!"
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Covid isn't a flu nor is it as mild as the deadliest flu we've had in last 70 years. We've already passed up the body count for that late 1960s one. Virus has different structure anyway, different phylum. Flu isn't a coronavirus.
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Can confirm... got my booster today. They didn't even ask for my name - just told me to write it on the card later.
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Are there any pros or cons for a regular person to get a third shot?
It would be as easy as just walking into a CVS. In fact, I got my first shot from my regional health department - a three hour round trip - and my second shot at CVS because it's nearby and they had it in stock by then. One result being I am now counted as TWO people who are not fully vaccinated. So take that 40% with a grain of salt. It might not be accurate.
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- You are now safer than ever before
- You can virtue signal harder on social media
- You can stick it real good to those evil deplorable Republicans
Cons:
- Does it matter? Look at all the pros.
Go for it, CubicleZombie. You are a perfect candidate for boosters.
Serious Pro/Con (Score:2)
Are there any pros or cons for a regular person to get a third shot?
Seriously, let's look at those.
First:
If you had a full vaccination scheme, you're already reducing you're risk of having/carrying (assymptomatically) the virus, of passing it on, of developing a symptomatic COVID-19 disease, of those symptoms worsening to the point of necessitating a hospitalisation, of the situation worsening to the point of needing transfer to ICU, and finally of death.
Pro:
- If you take a booster shot, it will increase somewhat your antibodies, helping to counteract the slightly diminishe
Re: Already got mine (Score:2)
Are there any pros or cons for a regular person to get a third shot?
Isn't it a microaggression to suggest that transplant recipients aren't regular people?
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The mistake was around improper reporting, which was bad, because it gave Nursing homes a false sense of safety. Because the deaths from Covid happened after they were admitted to the Hospital, so they were mostly counted as hospital deaths.
But these GOP Governors are just Evil, outlawing attempts for businesses and local governments to take measures to keep their staff and customers safe. So other than just not putting in a Masking Mandate, the told Private Companies and other places of work, that they ca
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I understand that's an easy position to take and I usually refrain from being pigeonholed into such a group of people. Cuomo needed to go, so does Matt Gaetz.
Only polarized idiots pull such, my guy good, your guy bad, crap.
These are willing participants who have something to gain, and not much to lose. I am hopeful as I have two relatives who fall under this category of immunosuppresion. I would love for their lives to be just a bit more at ease right now.
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You guys must be pretty scared of the upcoming elections to lie like that. I'm not sure why you bother to do it here anyway. You are just posting to an echo chamber.
They genuinely believe what they say. It's a mental illness. Well, cognitive dissonance is a normal thing. But libs take it to the mental illness level.
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DeSantis has gone full cartoon villain at this point. Withholding funds from public schools and even threatening to withhold people’s paychecks for defying him. He says stop making things political. Why is he legislating medical requirements? I don’t call up DeSantis to ask questions about my blood pressure. My body my choice, unless I want to ingest recreational drugs or have an abortion. Then suddenly it’s not my body or my choice.
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0/10 lame troll attempt. So giving people a choice by punishing school children via reduced funding? Makes perfect sense.
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Says right here he is threatening funding. https://www.npr.org/sections/c... [npr.org]
Again, why is he against CDC guidelines?
no immune response (Score:2)
Uh, no to no immune response. There are many immune responses. It's a complicated system. What is they mean is: no immune response of the kind they normally go looking for, ordinarily in normal people.
Perhaps being on immunosuppressants means that looking in all the normal places is the wrong way to skin the cat.