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Medicine

Three Die After Untreatable 'Superbug' Fungus Infections in Two Different Cities (go.com) 95

"U.S. health officials said Thursday they now have evidence of an untreatable fungus spreading in two hospitals and a nursing home," reports the Associated Press: The "superbug" outbreaks were reported in a Washington, D.C, nursing home and at two Dallas-area hospitals, the Centers for Disease Control and Prevention reported. A handful of the patients had invasive fungal infections that were impervious to all three major classes of medications. "This is really the first time we've started seeing clustering of resistance" in which patients seemed to be getting the infections from each other, said the CDC's Dr. Meghan Lyman...

Health officials have sounded alarms for years about the superbug after seeing infections in which commonly used drugs had little effect. In 2019, doctors diagnosed three cases in New York that were also resistant to a class of drugs, called echinocandins, that were considered a last line of defense. In those cases, there was no evidence the infections had spread from patient to patient — scientists concluded the resistance to the drugs formed during treatment. The new cases did spread, the CDC concluded....

Those cases were seen from January to April. Of the five people who were fully resistant to treatment, three died — both Texas patients and one in Washington.

Lyman said both are ongoing outbreaks and that additional infections have been identified since April. But those added numbers were not reported.

The fungus, Candida auris, "is a harmful form of yeast that is considered dangerous to hospital and nursing home patients with serious medical problems," they add — and it's spread through contaminated surfaces or contact with patients.

Newsweek points out that while it's only recently appeared in America, "infections have occurred in over 30 countries worldwide."
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Three Die After Untreatable 'Superbug' Fungus Infections in Two Different Cities

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  • For the west, Nosocomial disease, which is the spread of a disease in hospitals, typically occurs because hospitals are not clean and their workers do not care enough to clean between rooms. The problem is, that this tends to create superbugs, i.e. drug resistant bugs, as we make heavy use of antibiotics in hospitals and compromised patients are WONDERFUL bioreactors.
    Before going in for a surgery, look at the hospital and see what the nosocomial rates are. Otherwise, the price you pay may be high. An ex-s
    • by Anonymous Coward
      Did you even read the headline? This is a fungus, so using all the antiseptic and antibiotics in the world will not do anything to it.
      • by Geoffrey.landis ( 926948 ) on Saturday July 24, 2021 @05:35PM (#61616889) Homepage

        Did you even read the headline? This is a fungus, so using all the antiseptic and antibiotics in the world will not do anything to it.

        Antibiotics, definitely useless.

        Antiseptics... depends on which one. Antiseptics are basically cleaning agents that kill cells. Whether they work against fungus will depend on which ones. Iodine, for example, is the classic old-fashioned antiseptic; it's effective against fungus.

          https://www.reviewofophthalmol... [reviewofop...mology.com]

        • by Anonymous Coward

          What about bleach, or ultraviolet light? Or at least sunlight, which everyone will tell you is the best disinfectant? Maybe the doctors can figure out some way to apply those to treating an infection. Inject them at the site of the fungus, or whatever. This could be a bigly cure!

        • by HiThere ( 15173 )

          It's not at all clear that iodine is effective against *this* fungus. When they start using "last resort medicines" you can probably be fairly sure they've already tried the more common ones. So I would guess that it wasn't effective. And there is a fungus, probably this one, where hospitals have needed to tear down the paneling of the rooms in which the patients with the fungus have been kept in order to disinfect them. I'd guess that if iodine, bleach, etc. would do the job, that they wouldn't have go

          • It's not at all clear that iodine is effective against *this* fungus. When they start using "last resort medicines" you can probably be fairly sure they've already tried the more common ones.

            Since the article says "The fungus, Candida auris, is a harmful form of yeast that is considered dangerous to hospital and nursing home patients with serious medical problems. It is most deadly when it enters the bloodstream, heart or brain", by the time the patients are in the need of "last resort medicines", it's far too late to get any benefit from topical antiseptics.

            I wasn't suggesting that antiseptics could have saved the patients who died. I was merely correcting the statement that antiseptics "don't

          • Depends. You can't use iodine internally, and a fungal infection can be internal.
        • Where are you guys getting this nonsense about antibiotics being useless against fungus? Many antibiotics are indeed used against certain fungal infections

          https://www.ncbi.nlm.nih.gov/b... [nih.gov]

      • Hydrogen Peroxide normally kills fungi.

      • You have misconception, some antibiotics do indeed work against certain fungal infections.

        https://www.ncbi.nlm.nih.gov/b... [nih.gov]

    • by 93 Escort Wagon ( 326346 ) on Saturday July 24, 2021 @05:14PM (#61616841)

      On a side note, the majority of today's superbugs, are coming from china, where they are created on the animal farms because they make heavy use of antibiotics at will on their food animals.

      This is standard practice "in the west" too.

      It's stupid, but we do it - in the name of short-term profitability.

      • by hey! ( 33014 ) on Saturday July 24, 2021 @07:08PM (#61617125) Homepage Journal

        It's not so much short-term vs. long-term as it is what economists call externalization. It creates a benefit enjoyed by the feed lot operator at the expense of a cost that is borne *by society at large*.

        • by HiThere ( 15173 )

          That's certainly a component, but I think it's probably also largely short term vs long term. People are know to sharply discount future rewards and penalties.

        • It's not so much short-term vs. long-term as it is what economists call externalization. It creates a benefit enjoyed by the feed lot operator at the expense of a cost that is borne *by society at large*.

          There seems to be a lot of people that missed that lecture in Econ 101. Those people are called "free-market capitalists".

      • by Entrope ( 68843 )

        It has been illegal to use "medically important" (that is, important to human health) antibiotics for production purposes, rather than for specific animal health purposes, in the US since 2017: https://www.cdc.gov/drugresist... [cdc.gov] (look for the bit about GFI #213).

      • nope.
        Long ago, the west quit using it in LARGE quantities, though we have NEVER used it to the degree that China does. Why? Because of this very issue. That does not say that antibiotics are not being used, but they are not for steroidal or preventive. However, if an animal in a stockyard pen is sick with something, then all of the animals in that pen will have the antibiotics in their food to stop the spread. Far better would have been to split the animal off and treat it, but...

        For the west, we now h
        • This! We don't need to dope our cows, we do that to the people directly. Go to the doctor and say you have a runny nose, you'll come home with antibiotics. Hell I'm surprised they haven't promoted it as a COVID cure yet.

      • by gweihir ( 88907 )

        On a side note, the majority of today's superbugs, are coming from china, where they are created on the animal farms because they make heavy use of antibiotics at will on their food animals.

        This is standard practice "in the west" too.

        It's stupid, but we do it - in the name of short-term profitability.

        Indeed. Even is such short-term "cost savings" universally turn out to be very expensive overall. The tragedy of the commons, perpetuated by abject stupidity and unfettered greed. Always the same crappy story with humans.

    • Before going in for a surgery, look at the hospital and see what the nosocomial rates are. Otherwise, the price you pay may be high.

      Truly words to the wise!

    • Before going in for a surgery, look at the hospital and see what the nosocomial rates are.

      Wait what, you guys chose your hospitals?

  • 1. Release a fungus from secret Chinese lab to old folks home.

    2. ??? 3. Profit.

  • Wonder what the next five plagues will be.
    • What do the horsemen have to say?

  • by hey! ( 33014 ) on Saturday July 24, 2021 @05:15PM (#61616843) Homepage Journal

    Most people think of fungi like mushroom as plants, but in fact fungi are more closely related to animals [tolweb.org] than they are to plants. And of course plants, animals and fungi are more closely related to each other than they are to bacteria [tolweb.org].

    The practical significance it's harder to find broad-spectrum antifungals that won't also harm us than it is to find broad spectrum antibiotics (i.e., anti-bacterial drugs). There's only three classes of systemic antifungal medications and there's dozen or more classes of antibiotics.

  • When antibiotics get overused and you wipe out the bacteria, something else will take their place...
    That's why their use should be prohibited, like they've been doing in Norway for a a while now.

    • When antibiotics get overused and you wipe out the bacteria, something else will take their place...
      That's why their use should be prohibited, like they've been doing in Norway for a a while now.

      Let's say "Limited", rather than "Prohibited".

      I personally would not like to live in a world where Antibiotics were actually Prohibited!

      • by suss ( 158993 )

        It's prohibited, unless there is no other alternative, that goes further than just "limited".

        Antibiotics are not going to help anyway, after overuse makes them ineffective.

        • In the Netherlands you can buy only aspirine without a doctor's prescription in any apothecary. And those are the 100 milligram pills. Heavier apirine needs to be prescribed by a doctor, before any apothecary is even allowed to sell it to you.

          And when you can walk into the doctor's waiting room on your own accord, it is highly likely that you get a prescription for heavier aspirine and nothing else. Usually you get a invitation to come back in 3 days or so to see if the complaint went away by itself.

          Doctor'

          • In the Netherlands you can buy only aspirine without a doctor's prescription in any apothecary That seems a bit overly regulated. What about paracetamol and ibuprofen? Where i live, you can now buy CBD oil over the counter. It's very expensive but there for people who need it.

          • by suss ( 158993 )

            Anyone can buy Aspirin 500mg at any pharmacy in the Netherlands. Brand name Bayer costs about 4.50 euro for 20 pills...

            • Anyone can buy Aspirin 500mg at any pharmacy in the Netherlands. Brand name Bayer costs about 4.50 euro for 20 pills...

              That sounds exorbitant; but more believable than "You can only buy 100mg Aspirine[sic]."

              After all, Aspirin has nothing to do with Antibiotics. Maybe Aspirine does, however!

    • Are you suggesting that lethal bacteria strains have been controlling yeast populations in hospitals?

    • Wiping out Politicians has the same effect. Others (usually worse) just rise up to take their place.

    • Antibiotics do not treat fungal infections, only bacterial infections.
  • ... A Fungus Among Us [youtube.com].

  • There are very few classes of antimycotics to treat any yeast or fungal infections. C. auris is resistant to most of them because of the overuse of azole antifungals agriculture. Similar threats exist to antibiotics because of their overuse in meat agriculture.

    C. auris is especially stubbornly-resistant to hospital industrial cleaners such that tiles have to be ripped-out and equipment thrown away as it's not autoclavable or cleanable.

    What's worse is for-profit hospitals may try to keep it quiet which of th

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