Slashdot is powered by your submissions, so send in your scoop

 



Forgot your password?
typodupeerror
×
Medicine Science

Autopsies Reveal the Terrible Damage COVID-19 Can Inflict On the Human Brain (sciencealert.com) 162

"As COVID-19 relentlessly infects more and more of us, scientists are getting a close look at the strange and frightening damage it can inflict on our bodies," writes Science Alert (in an article shared by long-time Slashdot reader AmiMoJo): We've known since early in the pandemic this disease wreaks havoc on more than just the respiratory system, also causing gastrointestinal conditions, heart damage and blood clotting disorders. Now, a year into the pandemic, in-depth autopsies of COVID-19 patients have revealed greater details of widespread inflammation and damage in brain tissues. This may help explain the deluge of neurological symptoms that have manifested in some patients, from headaches, memory loss, dizziness, weakness and hallucinations to more severe seizures and strokes.

Some estimate that up to 50 percent of those hospitalised with COVID-19 could have neurological symptoms that can leave people struggling to do even common daily tasks like preparing a meal. "We were completely surprised. Originally, we expected to see damage that is caused by a lack of oxygen," said physician and clinical director at National Institute of Health (NIH), Avindra Nath. "Instead, we saw multifocal areas of damage that is usually associated with strokes and neuroinflammatory diseases...."

Their report was published in the New England Journal of Medicine.

The article also remembers a September remark by a University of Liverpool neurologist to Nature magazine back in September who had also suggested possible neurological symptoms from COVID-19. "We've seen this group of younger people without conventional risk factors who are having strokes, and patients having acute changes in mental status that are not otherwise explained."
This discussion has been archived. No new comments can be posted.

Autopsies Reveal the Terrible Damage COVID-19 Can Inflict On the Human Brain

Comments Filter:
  • by spun ( 1352 ) <loverevolutionary&yahoo,com> on Saturday January 09, 2021 @02:39PM (#60916680) Journal

    This is completely expected, the virus attacks and degrades blood vessels. This has been known for almost a year.

    The danger here is that it is disproportionally stupid people who choose to expose themselves and their families to the virus. So they'll get even dumber. Red states are choosing to become literal Idiocracies.

    • This is completely expected, the virus attacks and degrades blood vessels. This has been known for almost a year.

      The danger here is that it is disproportionally stupid people who choose to expose themselves and their families to the virus. So they'll get even dumber. Red states are choosing to become literal Idiocracies.

      Indeed. It came up as 8 months ago a result of the New York Times together with other Integrity Initiative outfits peddling the conspiracy theory that the Russians are concealing their death toll - articles in NYT and Novaya (April), Guardian (early May), etc.

      They did not (at least in the cities where NYT claimed them to do so) They went and did autopsies some of the "surplus" cases as well as statistical analysis and published the results - a huge spike in cardiovascular deaths including 2-4 times incre

    • by shanen ( 462549 )

      This is completely expected, the virus attacks and degrades blood vessels. This has been known for almost a year.

      The danger here is that it is disproportionally stupid people who choose to expose themselves and their families to the virus. So they'll get even dumber. Red states are choosing to become literal Idiocracies.

      Sad that this needs to be quoted against trollish censor moderation. (But it's actually a kind of vanilla FP.)

    • https://www.health.harvard.edu... [harvard.edu]

      When To Call a Professional
      Adults and children should seek immediate medical attention for any fever of 104 degrees Fahrenheit (40C) or higher or for any fever accompanied by one or more of the following:

      Convulsion
      Loss of consciousness
      Confusion
      Stiff neck
      Difficulty breathing
      Severe pain anywhere in the body (especially the head, chest or abdomen)
      Swelling or inflammation of any part of the body
      Vaginal discharge that is discolored or foul-smelling
      Urinary tract symptoms (pain on urination, foul-smelling urine)

      Call a doctor immediately if an infant younger than 3 months develops any fever.
      For a lower fever of unexplained origin, call your doctor if it does not improve after two to three days. Call sooner if you develop additional symptoms.

      Prognosis
      For most fevers caused by common infections, the person either recovers on their own or the doctor is able to identify and treat the cause.

      Sustained body temperatures of 106 degrees Fahrenheit (41.1C) or above can cause brain damage.

      And that's just the FEVER ALONE. The symptom, not the actual health problem.
      Or other health issues, like secondary bacterial infections of heart and lungs due to the disruption of bodily homeostasis.
      Which, again, high fever will cause all on its own.

    • by xwin ( 848234 )
      How is this only Red states problem? CA has by far largest number of cases and is 3rd by number of deaths behind NY (blue state) and Texas (red state). https://www.worldometers.info/... [worldometers.info] Soon CA will surpass Texas by the number of deaths. Why does this have to be political? To paraphrase what someone said in another thread - "the silver lining to this pandemic is that liberals are dying in the greater numbers". This is why US in in the first place by number of infections and deaths - instead of joining forc
      • by spun ( 1352 )

        California, and especially southern California, is home to a huge number of white supremacist racist goons. Orange county, for example, has been extremely badly hit by covid, thanks to the fact that the mouth breathers there won't wear masks.

        Yes, I rejoice when traitors die. "The tree of liberty must, from time to time, be watered with the blood of tyrants." And yes, anyone who still supports Trump is a traitor.

    • We've seen what a mob of zombies can do in the cinemas and on 01/06.

    • by vbdasc ( 146051 )

      The virus itself does no such thing. The misguided immune response to it is the real culprit for the blood vessel and organ damage.

    • by AmiMoJo ( 196126 )

      To me the most important thing to take away here is that we won't get back to normal this year.

      At the rate we can vaccinate people and the effectiveness of the vaccine (70-90% depending which one you get) you aren't going to be safe from COVID this year. You still need to take care, stay away from the office and other crowded places.

      If you don't you risk brain damage.

    • by MrL0G1C ( 867445 )

      Summary is missing the meat of the issue, what happens and why it happens which is odd to say the least when the scientists have a good idea what is going on, an article about it was posted here previously.

      The mumps part of the MMR jab happens to give a lot of immunity to COVID19. https://mbio.asm.org/content/1... [asm.org] Strong inverse-correlation between the vaccine titers and COVID symptom severity. There has also been shown to be strong correlation between Vitamin-D deficiency and Zinc deficiency and COVID-19 s

  • by Firedog ( 230345 ) on Saturday January 09, 2021 @02:54PM (#60916790)

    If COVID can have these kinds of effects on the brains of younger people, imagine the damage it could do to the brain of an obese 74-year-old man (hypothetically speaking, of course).

  • 1) Huh, so they all had Covid!
    2) Thank Jeezuz I don't have a brian!
    3) Causes terrible damage on the human brain... like you know who.

    They just write themselves!

  • by TomGreenhaw ( 929233 ) on Saturday January 09, 2021 @03:42PM (#60917050)
    Everyone seems fixated on the death rate and the fact that younger people don't die.

    We are going to solve that this year, but will be dealing with many millions of people permanently injured for a generation.

    If we can drive the fact that one may not die but be permanently maimed into people's thick heads, maybe they would wear an effective mask properly at all times in public.

    This is your brain - this is your brain on Covid.
    • by DrMrLordX ( 559371 ) on Saturday January 09, 2021 @04:29PM (#60917316)

      Except that the cited study never actually concludes that the observed brain damage can be definitively linked to Covid-19. In fact, it says the opposite: they aren't really sure.

    • by hey! ( 33014 )

      Yeah, the public health concerns are somewhat like the viral encephalitises, for example Eastern Equine (EEE). A major EEE epidemic in a state might be twenty or thirty cases, half of which die, so if you go by death rate per 100,000 population it's insignificant. But the cost of dealing with the survivors is staggering. Sometimes you have young people who have to spend the rest of their life institutionalized.

      Here there's a broad spectrum of "sequelae", few cases as bad as EEE, but in vast numbers.

    • I bet people will argue covid isn't to blame unless it directly kills your lungs; refusing to blame other direct damage let alone indirect harm... because of politics...
      I know two people who "recovered" with issues:

      1 is old and acts like she had a stroke; nearly a vegetable right now but she "recovered" from 3 weeks hospitalized from covid. Less than 1 week after then a bad stroke and was on blood thinners already.

      1 without symptoms: died from a heart attack recently. "natural death" except it was just week

    • Everyone I know is very aware of possible permanent damage. That's what scares me - not dying.

    • A few critical pieces of information are missing. One is the percentage of cases (not hospitalizations) that result in long term damage. Is this a big number compared to deaths. The other is the ratio of infections to cases. Together these would let us know if X people are exposed to COVID, how many will die, how many will have permanent disabilities. I don't know those numbers to at least a factor of 5X uncertainty. (if they are available, somewhere, I'm very interested in knowing)
  • by ModelX ( 182441 ) on Saturday January 09, 2021 @04:38PM (#60917356)

    So how do we know these changes are from COVID and from COVID alone?

    Were they brain scanned just before getting COVID, too? Could any of the other conditions also have contributed to the changes?

    • by khchung ( 462899 )

      So how do we know these changes are from COVID and from COVID alone?

      Were they brain scanned just before getting COVID, too? Could any of the other conditions also have contributed to the changes?

      No worries, with the covid petri dish that is called America, we have now at least 20 million samples across the whole population that scientists can study in the coming decades to careful tease out exactly how bad covid-19 can damage human beings.

      The rest of the world should thank Americans for volunteering to participate in this huge experiment.

    • Were they brain scanned just before getting COVID, too?

      That's not necessary. Given a large enough pair of samples you can isolate just the COVID damage - either taking into account confounds or sufficient sample sizes so there's no need to.

  • by hdyoung ( 5182939 ) on Saturday January 09, 2021 @05:35PM (#60917594)
    To anyone with a tiny bit of relevant biological knowledge, it's no surprise that COVID can cause neurological problems. It's a specific variant coronavirus that we're not yet adapted to - meaning that it can probably invade a lot of different tissues in the human body. A person with bad COVID is probably going to have damage in lots of places.

Every nonzero finite dimensional inner product space has an orthonormal basis. It makes sense, when you don't think about it.

Working...