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Medicine Science

A $5 Million Prize Spurs Competition for New Covid-19 Rapid Test 53

As countries race to develop a Covid-19 vaccine, just determining who's infected remains a major challenge. From a report: Large-scale testing is a crucial element in containing the virus, experts say, because many who contract it exhibit little to no symptoms. Without widespread testing, it's a daunting task to identify contagious individuals and isolate them. To help meet that challenge, the XPRIZE Foundation, which aims to spur technological and industry advancements, is offering a $5 million prize to develop a new Covid-19 rapid test. Competitors can enter until midnight Tuesday. Since July, 659 teams from 68 countries have registered. Currently, test results for the novel coronavirus can take up to two weeks, creating headaches for medical professionals, public-health experts and elected officials. Without the ability to test people often and with speedy results, many cases may go undetected, which can lead to new clusters of infections.

"We have, like everyone else around the globe, seen the impact this has had on mental health, physical health, bringing the wheels off of the economy," said Anousheh Ansari, chief executive officer of the XPRIZE Foundation. "We always look at innovation to solve grand challenges." Ansari and her family poured millions into funding the first XPRIZE in 2004 that launched the commercial space race. That $10 million prize brought in about $100 million of investment to the teams that competed, helping fuel what is now a more than $100 billion industry. Ansari's hope is that the Covid prize will seed a similar investment boom to fight a virus that has infected more than 27.3 million people and killed more than 892,000 worldwide.
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A $5 Million Prize Spurs Competition for New Covid-19 Rapid Test

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  • Until then... (Score:2, Insightful)

    by OMBad ( 6965950 )
    ...wash your hands, wear a mask, SOCIAL DISTANCE (most important part, even with a mask on). Do not leave your house unless you have to. In about six months the vaccines will start arriving. Until then, stay inside.
    • Testing (Score:1, Interesting)

      by Anonymous Coward

      Large-scale testing is a crucial element in containing the virus, experts say, because many who contract it exhibit little to no symptoms.

      Such a deadly disease that you have to be tested for it to even know you have it.

      • "Such a deadly disease that you have to be tested for it to even know you have it."

        You mean like Cholera, Ebola, Marburg etc where you can transmit it to hundreds of people before showing symptoms?

        Yes, indeed, all Coronavirus-infections go in this same group, not only this one.

    • Do not leave your house unless you have to. In about six months the vaccines will start arriving. Until then, stay inside.

      Go ahead. The rest of us have work to do.

    • It is an interesting time, things are really bad, so that the news agencies want to give us some good news. However this good news is often causing the normal folks to do harmful things.

      The damage is long term. Don't expect things to get back to normal regardless who gets elected. We need a Vaccine that is proven safe and effective. Even if the formula is out now, it isn't proven safe and effective yet, so it will not be sent to the general public for a long time. Then when it is sent to the general pu

    • Wash your hands: agree or at least use sanitiser if traveling. Wear a mask: yep where local regs require me to. Sociwl distance , yep distepsnce an group size set by local/national regs. Hope mu formating works as preview is not available on mobile
    • Do leave your house to go for a walk or exercise in public areas where there aren't other people around (in suburbs or rural areas). Otherwise I agree.

  • by Anonymous Coward

    Which country has failed the hardest to respond to Covid-19?

    America.

    Which national leader has killed the most people through incompetence and malevolence?

    Trump - 150,000 of 180,000 deaths are squarely on his hands.

    Which country's nationals are still banned from international travel in fucking September due to widespread Covid-19 spread?

    America.

    Seriously what the fuck?!

    • CDC has quietly revised those numbers from 150,000 to a little under 10,000 covid only deaths in the background. You are being lied to and are eating it up. Don't believe me or the news, look it up on the cdc website.

      On a side note, a vaccine isn't going to fix anything even if it does work.

      The people on the right are not going to take as they don't want to be guinea pigs on version 0.1 of the vaccine. The government has to earn their trust on issues. (Seriously there are large law firms that just wo
      • by q_e_t ( 5104099 )

        CDC has quietly revised those numbers from 150,000 to a little under 10,000 covid only deaths in the background. You are being lied to and are eating it up. Don't believe me or the news, look it up on the cdc website.

        I did. https://www.cdc.gov/nchs/nvss/... [cdc.gov]. There is no 'COVID-only' category, even. All deaths involving COVID-19: 174,626

  • As a layman I am surprised that rapid, readily-available tests have not already been created and distributed widely. Even if they are not 100% accurate. My ignorance is at play here. In my fantasy world I envision a simple cough test onto a strip of coated paper that turns some color if the virus is present.
    • by Zak3056 ( 69287 )

      I'm also surprised by this, and am assuming there must be more that the article isn't addressing. My company has been screening its employees with a 10 minute rapid test since early April. it costs us $35 a test, and that includes the test kit, the trained person to administer it, and that person's travel time to our designated test site.

    • Re: (Score:2, Insightful)

      As a layman I am surprised that rapid, readily-available tests have not already been created and distributed widely.

      Why should you be surprised when the con artist has said we should do LESS testing because all this testing makes us look bad [businessinsider.com].

      Even his failure of a son-in-law, Jared Kushner, sabotaged a nationwide testing program [vanityfair.com] because it would have helped blue states. This was after $52 million of taxpayer money was funneled to a United Arab Emirates company for the (possibly illegal) purchase o
    • https://news.osu.edu/ohio-stat... [osu.edu]

      A gadget like that which can be reprogrammed via a download to catch the next virus of the day. Want to get on the bus full of people, just prove you aren't sick first. It would make stopping a pandemic incredibly easier than what we are trying to do.

    • I'm also surprised and disappointed. There's plenty of blame to go around: massive $$$ focused on cool war machines, little to pandemic threats; govt agencies dedicated to this threat, but only have a binder of Powerpoint slides to show for it, warm up examples in H1N1/SARS, and the miserable response of the current administration including state leadership.

      We had the genome for this at the beginning of the year, and with broad, frequent, cheap testing, covid becomes manageable, at least to the point that

      • by q_e_t ( 5104099 )
        Large numbers of organisations are focused on this. It's just that difficult things are difficult to do.
    • by hey! ( 33014 )

      The actual physical quantity of virus in your fantasy scenario is tiny. It has to be amplified millions of times to be detected, through a process called polymerase chain reaction (PCR). This involves an annealing-like procedure in which you repeatedly heat and cool the sample in the presence of special enzymes.

      In contrast antibody tests measure your body's response to the virus, which is orders of magnitude larger and usually doesn't require any kind of amplification procedure. But antibody tests don't

      • While you've laid out the challenges well, in fairness to the OP, there are technology and sensors in other fields that can detect things of the same small magnitude. We're all just wondering given the enormous potential damage in health and economically to society, why stronger efforts weren't directed towards rapid (instant), cheap, testing earlier on. Testing gets you safely through the period leading up to and through dispensing a vaccine.

        I had a PCR test done back in June and got the results 8 days

        • by hey! ( 33014 )

          The difference in this scenario from other ones where you're detecting tiny concentrations of a substance is that a droplet of any bodily fluid is a witch's brew of organic molecules. A test needs to be both sensitive and discriminating, two goals that are hard to achieve together.

          A sensitive reagent that reacts with a target molecule will also tend to react, albeit less strongly, with non-target ones. That's why test results are often reported as "titers" -- the greatest level of dilution that will achiev

    • by dryeo ( 100693 )

      Imagine a test that is 98% accurate. 50 people gather after all testing negative and on average one of those people may be positive and infect the other 49 people

      • by q_e_t ( 5104099 )
        It needs to be sensitive and specific. I could create a test with zero false negatives by having one that always said you had COVID... Or one with no false positives just as easily. As noted above, you need the appropriate level of both and it is often a trade off. I say appropriate level as in some instances a moderately inaccurate test can be useful if you do follow up tests and the first triage test is cheap with next to no false negatives.
        • by dryeo ( 100693 )

          What worries me is too much dependence on an inaccurate test. As you say, testing is useful and a 98% test used multiple times on a person should be fairly accurate but to allow people to ignore all health protocols based on one quick test doesn't seem like a solution.

          • by q_e_t ( 5104099 )
            Even 90% can be useful. E.g. a cheap test which has zero false negatives, 10% false positives for disease A which is dangerous is fine if you apply it to people with purple spots (which people with disease A have, but also people with mild disease B) if, say, 50% of people actually have A and 50% have B. Out of 100 people you'd tend to get 10% of 50 people, i.e. 5 falsely identified as having virulent illness A, but then you'd do other tests and discover they weren't. But don't have to do the expensive test
  • by Wdi ( 142463 )

    Maybe a nice incentive for university groups to showcase their experimental technology - but 5 Millions is FAR less than what is required to develop a certified test. Big Pharma will simply ignore it since probably every serious developer in these circles is working with a 500 Mil budget already, and these are the only guys who can actually bring something to market fast because they have all the knowledge and infrastructure bundled on site.

    Don't forget: The XPrize lunar lander competition was scheduled to

  • In the continuing devolution of the XPRIZE brand, we now have a prize that far too late, is less than 1/100 of what the NIH and NSF government programs are, and is absurdly focused on not developing new technology. Really, $5M for a project like this is absurdly small, particularly when there is absolutely no need to convince investors of the value of a COVID test! The government programs have already gone through application, evaluation, launch, and first milestones. The commercial folks who started worki

  • It seems like the potential profits from such an invention would be enough encouragement to get people to work on this.

    Even if they were sold very cheaply, it seems like $5 million would be just a drop in the bucket.

  • by vinn01 ( 178295 ) on Tuesday September 08, 2020 @03:06PM (#60485580)

    Compare this $5 million prize to the cost of a major motion picture having a budget of $200 million (Tenet, released August 2020).

    The XPRIZE Foundation offer for a worldwide rapid Covid-19 test is about 2.5% of the cost of this major motion picture. The XPRIZE Foundation offer amounts to less than 4 minutes of the 150 minute film.

    Do we really want to fight a virus that has infected more than 27.3 million people and killed more than 892,000 worldwide, or do we want a couple hours of entertainment?

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