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Medicine Science

Warning of Serious Brain Disorders in People With Mild Coronavirus Symptoms (theguardian.com) 235

Doctors may be missing signs of serious and potentially fatal brain disorders triggered by coronavirus, as they emerge in mildly affected or recovering patients, scientists have warned. From a report: Neurologists are on Wednesday publishing details of more than 40 UK Covid-19 patients whose complications ranged from brain inflammation and delirium to nerve damage and stroke. In some cases, the neurological problem was the patient's first and main symptom. The cases, published in the journal Brain, revealed a rise in a life-threatening condition called acute disseminated encephalomyelitis (Adem), as the first wave of infections swept through Britain. At UCL's Institute of Neurology, Adem cases rose from one a month before the pandemic to two or three per week in April and May. One woman, who was 59, died of the complication. A dozen patients had inflammation of the central nervous system, 10 had brain disease with delirium or psychosis, eight had strokes and a further eight had peripheral nerve problems, mostly diagnosed as Guillain-Barre syndrome, an immune reaction that attacks the nerves and causes paralysis. It is fatal in 5% of cases.
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Warning of Serious Brain Disorders in People With Mild Coronavirus Symptoms

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  • by 140Mandak262Jamuna ( 970587 ) on Wednesday July 08, 2020 @02:38PM (#60276368) Journal
    All the Red state Governors assured their residents, they are safe and they would not be affected.

    This only affects people with brains, and so they are laughing at the blue states, "ROTFLAMAO Einstein! brain is over rated, do you agree it at least now?"

    • by geekmux ( 1040042 ) on Wednesday July 08, 2020 @03:01PM (#60276496)

      All the Red state Governors assured their residents, they are safe and they would not be affected.

      This only affects people with brains, and so they are laughing at the blue states, "ROTFLAMAO Einstein! brain is over rated, do you agree it at least now?"

      Coming from an intelligent American who's a fan of comedy and reasonable thought, these kinds of jabs aren't even worth a punch line anymore.

      The political civil war being waged right now, is costing innocent lives. Our leaders don't care, and our citizens are too stupid to blame them. Instead, it's just endless shit-slinging between the two parties. Red and Blue don't represent politics anymore. They're fucking gang colors now. One would expect those claiming to be armed with brains, are smart enough to realize that.

      Obviously not, and so the Devolution of America by both sides, continues...

      • by PopeRatzo ( 965947 ) on Wednesday July 08, 2020 @07:20PM (#60277390) Journal

        The political civil war being waged right now, is costing innocent lives. Our leaders don't care, and our citizens are too stupid to blame them. Instead, it's just endless shit-slinging between the two parties. Red and Blue don't represent politics anymore. They're fucking gang colors now. One would expect those claiming to be armed with brains, are smart enough to realize that.

        Obviously not, and so the Devolution of America by both sides, continues...

        The assertion that "both sides are equally to blame" is morally lazy, logically flawed, and factually inaccurate. If there was ever a time that required discernment, it's now. Your "both sides"-ism lets the culpable off the hook and tarnishes those who are trying to help. Moral equivalence is worse than unhelpful. Try to be better.

        • by 140Mandak262Jamuna ( 970587 ) on Wednesday July 08, 2020 @07:28PM (#60277414) Journal
          In divider's logic, "We are responsible for 90% of the damage caused, but we get only 50% of the blame! We win".

          That is the effect of this both-siderism. Both sides are not equal. One side is much much less responsible for the division. You can guess which side *I* think is responsible for the damage. But I try to be neutral, and let you decide which side is more responsible.

        • I've heard enough D's calling for censorship in the last year to say that both sides are harmful.

          By now anyone who relies on rhetoric instead of evidence is part of the problem, not the solution. Or they are a comedian.
      • Red and Blue don't represent politics anymore. They're fucking gang colors now.

        I've already felt this way for a long time, but hearing it the way you've quoted it still blows my mind.

  • by dmay34 ( 6770232 ) on Wednesday July 08, 2020 @02:40PM (#60276380)
    It causes brain damage! Covid is a GOP conspriacy to turn Americans into Trump voters!
  • by Anonymous Coward on Wednesday July 08, 2020 @02:46PM (#60276424)

    I was wondering why Trump was acting so hard to promote Covid-19 spread with his administration.

    What I still don't understand is why people of his party choose to go along with it. Weird self-selection mechanism that party has.

  • Numbers matter (Score:5, Insightful)

    by joe_frisch ( 1366229 ) on Wednesday July 08, 2020 @02:49PM (#60276434)

    At what rate relative to the death rate?
    If the number of people suffering from long term health effects is small compared to the death rate, it doesn't significantly change how we should react to the virus. OTOH if the long term disability cases are much larger than the number of deaths, that might suggest different policies.

    As it is we just know that "some" people have long term disabilities as a result of the virus. One in a million? One in ten? Anyone have actual statistics?

    • Re:Numbers matter (Score:5, Insightful)

      by CrimsonAvenger ( 580665 ) on Wednesday July 08, 2020 @03:10PM (#60276550)

      At what rate relative to the death rate?

      Only clue is that they've seen this in "more than 40 patients"....

      Which implies "fewer than 50 patients". Out of more than 300K patients who have had covid-19 in UK...

      • Comment removed based on user account deletion
      • "more than 40 patients"....

        Which implies "fewer than 50 patients".

        A billboard for a local hospital chimes in: "We're one of the top 22 hospitals in the state!"

        Really? I do SO wonder exactly where you placed! Maybe # 2.2?

      • by HiThere ( 15173 )

        A valid criticism, as long as you don't think they've seen all the cases. What you need to know is "40 out of how many you've looked for the symptoms in?"

        Another question would be "Would a general practitioner have noticed the problems you're noticing?" Not quite as relevant, but necessary to place things in context. You need to know not only how much you found, but also how much you looked at, and what someone else would have seen.

        That said, I think that these things being detected is currently quite ra

    • These are good questions... But I think the bigger issue here is that there are a lot of unexpected effects that are only now slowly being acknowledged/observed. We're not taking into account all of those effects in our covid responses yet, so it's important to discuss them as we become aware so we can respond most effectively.

      In particular, this type of news lends support to the utility of requiring masks in public, since we know there are potential unknowns, but we don't yet know the extent.

    • Also, how often do those issues occur without Covid-19. Or how often does it happen with other things like the flu? It was my understanding that a common cold or flu has a slight chance of kicking off all kinds of awful immune disorders. Even the bacteria in your mouth can cause your immune system to go after your heart.

    • At what rate relative to the death rate?
      If the number of people suffering from long term health effects is small compared to the death rate, it doesn't significantly change how we should react to the virus. OTOH if the long term disability cases are much larger than the number of deaths, that might suggest different policies.

      As it is we just know that "some" people have long term disabilities as a result of the virus. One in a million? One in ten? Anyone have actual statistics?

      I'm guessing that will be the subject of future studies. This paper seems to be more of a confirmation that this is a real problem that needs additional study.

    • by hey! ( 33014 )

      That's not necessarily the case. The *proportion* of cases with "neurological sequelae" doesn't have to be very large to be a serious concern, especially if the *total number* of cases is very large. Brain damage is life changing and can burden society and family members with enormous long term costs.

      Recent estimates of stroke prevalence among confirmed COVID-19 cases are actually running about 1.5%, which happens to be lower than the reported case fatality rate, but is nothing to take likely when you hav

    • to the effected people. Hell, depending on the severity of the brain damage it may never matter to them again.
      • That may be so, but numbers are important for society to decide how to respond to issues.

        Can't just make sweeping changes across society because a couple people were negatively affected by everyone. (At the same time, it doesn't mean we should ignore warning signs from small groups of people.)

    • by HiThere ( 15173 )

      And that's a really tricky question. Some of the damage, like minor kidney damage, is quite difficult to detect...and reports are that there is essentially no recovery. You just start off with a bit over twice the kidney capability you need, and as long as too much isn't damaged, you never know you're approaching the need for occasional dialysis. Similarly for small strokes. They're quite difficult to detect...unless they happen somewhere crucial. But you don't recover. What you do is switch some exce

  • What about brain disorders in people who don't have it yet but are stupid enough to engage in risky behavior? Shouldn't we put those them in an asylum?

  • by Joe2020 ( 6760092 ) on Wednesday July 08, 2020 @03:07PM (#60276530)

    The term "disorder" is usually used with mental illnesses where the term is meant to describe thought processes as no longer having an orderly behaviour, hence disorder. When people have a split personality, lack attention or have mood swings then this is described as a disorder. The stress, which people experience and the changes we go through due to the outbreak can also trigger mental disorders without someone actually being infected.

    So to describe the consequences of COVID19 on the brain as a disorder is somewhat misleading. Nerve and brain damage should be described as actual injuries and a better title would have been to call it "serious brain injuries".

If all the world's economists were laid end to end, we wouldn't reach a conclusion. -- William Baumol

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