Researchers Are Creepily Close To Predicting When You're Going To Die (arstechnica.com) 77
An anonymous reader quotes a report from Ars Technica: If death is in the cards, it may also be in your blood. Measurements of 14 metabolic substances in blood were pretty good at predicting whether people were likely to die in the next five to 10 years. The data was published this week in Nature Communications. A team of researchers led by data scientists in the Netherlands came up with the fateful 14 based on data from 44,168 people, aged 18 to 109. The data included death records and measurements of 226 different substances in blood. Of the 44,168 people, 5,512 died during follow-up periods of nearly 17 years.
The researchers then put their death panel to the test. They used the 14 blood measurements to try to predict deaths in a cohort of 7,603 Finnish people who were surveyed in 1997. Of those Finns, 1,213 died during follow-up. Together, the 14 blood measurements were about 83% accurate at predicting the deaths that occurred within both five years and 10 years. The accuracy dropped to about 72% when predicting deaths for people over 60 years old, though.
The researchers then put their death panel to the test. They used the 14 blood measurements to try to predict deaths in a cohort of 7,603 Finnish people who were surveyed in 1997. Of those Finns, 1,213 died during follow-up. Together, the 14 blood measurements were about 83% accurate at predicting the deaths that occurred within both five years and 10 years. The accuracy dropped to about 72% when predicting deaths for people over 60 years old, though.
There is a lot I can do with this information (Score:4, Insightful)
With this I can purchase just enough whiskey to last me the rest of my life.
Re: Sounds like a plot from a famous science ficti (Score:4, Insightful)
What are their plans for people who reveal such abnormal results?
5 and 10 years are standard terms for term life insurance and blood tests are already standard for larger policies. An 80% prediction rate would be an absolute gold mine for life insurance companies.
It would likely be valuable to medical companies as well especially if they could correlate the markers with specific diseases. Even more so if they could prescribe medicine or life changes that improved those markers. It wouldnâ(TM)t even necessarily have to improve your life expectancy, many times in medicine, improvement on the markers/symptoms is all it takes to sell people.
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Bad trolls are just gonna be bad trolls I guess. This guy should just commit seppuku, he's never gonna make it as a real troll.
And why is Biden so far ahead? I really think a Buttigieg/Harris ticket would be kickass. I also like Beto. As an old white guy, I say enough of the old white guys.
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Buttigieg is to young. Harris just wants to pass out free money to buy votes. Warren or Biden will have the best chance and really it's likely going to be Warren because Biden's really getting old.
Of course, if the Democrats don't get off their ass and vote in the swing states, Trump could very well win again. Sure, he doesn't have nearly 50% support, but if he can energize his base and really get them to vote in the swing states, we could see that happen again.
Luckily, we are more then a year away so we ha
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and without Russian Medaling this time.
The US still beats Russia in Golds!
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Actuaries (Score:5, Insightful)
I dunno ... I'm not impressed. I get the impression, but can't point to any specific data right now, that actuaries are pretty good at predicting mortality rates.
They are good at predicting mortality rates for populations. Not so much for specific individuals. The can get better results for smaller populations with specific data that is not generally available but even that has limits. For example smoking demonstrably shortens life expectancy but there are still people on the extremes of the probability curve. That said, if you have detailed medical data about someone you certainly can match them more accurately to an actuarial table and make more confident predictions about outcomes.
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Well, yes, but this method also has it's outliers, even when focused on individuals by medical history.
It's all known diseases (Score:5, Interesting)
It would likely be valuable to medical companies as well especially if they could correlate the markers with specific diseases.
After skimming the article:
a huge chunk of the markers are either lipids disease- or diabetes- markers.
You can file the report in the "No shit, Sherlock !" drawer.
(Joking. Of course, it's always useful when a well done large scale study can conclusively confirm what was previously very strongly presumed. I'm not saying that the confirmation is useless, just saying it didn't come as a surprise).
But to come back to your comment: yes, the corresponding disease are known (e.g.: hypercholesterolemia, Type 2 diabetes, etc.)
They are part of the diseases that can be monitored and treated, and means that indeed something can be done to try to help these people (even more so if the researchers do a follow-up study which confirms the causes of dead in those cases, and find out some of these could be avoidable).
This being done in one of our European Countries, which have a decent health policy (translation to you USians: it's one of those Evil Euro Communist countries), it means that such results are also a good argument to introduce some national policies to finance monitoring and treatment for those diseases (e.g.: offers this test for free every 5 year, make sure the corresponding drugs - e.g.: some statins - are fully reimbursed, etc.)
Regarding insurance companies: read again, this is a study done in a European country, one of thoses with proper health care sysyem, provacy policies, etc.
Not a 3rd-world country with corrupt for-profit health inssurance companies that will try to milk as much money as possible from "guaranteed to be perpetually in good health" clients and reject anybody who has the slightest chance of having a cold in the next 25 years.
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But whiskey is the main metabolic substance that they're testing for.
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Just as long (Score:2)
as I die with my boots on!
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I'm sure the rumors about your feet stench were greatly exaggerated.
Good! (Score:2)
If you know you are going to die in 10 years, you don't want to waste the time you have working until the day you die. I would much rather enjoy my final years aging gracefully as I swear like a sailor at children on Fortnite. ;)
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Despite the many flaws in the US healthcare system, particularly for the poor and middle class, it does currently forbid disqualification for preexisting medical issues... and for the wealthy, it is a great place to need medical care.
Anyway, what's the problem here? If Thanosian theory is correct, fewer human life-years in arguably the nation with the highest per capita consumption rate should please our more civilized European brethren.
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I want to know where I will die (Score:4, Insightful)
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What if the answer is "in bed"?
Re:I want to know where I will die (Score:4, Funny)
Sleep on the floor.
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Then I will want to know who I'm with and whether the amazing experience was the cause of my demise.
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What if the answer is "in bed"?
That's where fortune cookies would predict you would die if fortune cookies predicted death.
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I want to know where I will die ...then I'll just avoid going there.
Oh, well that's super easy!
The answer is: where ever you happen to be on March 20th 2023 at 10:25 am UTC
PS, I had to borrow some blood for other purposes, sorry about that.
PPS, but we had some of it tested for you, cheers!
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"The Appointment in Samarra"
(as retold by W. Somerset Maugham [1933])
The speaker is Death
There was a merchant in Bagdad who sent his servant to market to buy provisions and in a little while the servant came back, white and trembling, and said, Master, just now when I was in the marketplace I was jostled by a woman in the crowd and when I turned I saw it was Death that jostled me. She looked at me and made a threatening gesture, now, lend me your horse, and I will ride away from this city and avoid my fat
Volcano, Asteroid, WWW3? (Score:1)
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Recently, giant volcano in news, big asteroid, political turmoil, so How Soon?
So when I look at most politicians these days . . . and I mean all, internationally . . . I can only answer not soon enough!
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Maybe if we fill the giant volcano with politicians it will cool down. Actually, this sounds like something that should be done proactively.
Rather than Predicting how about Preventing Death? (Score:3)
In TFA there is a single mention of using the data to "targeted prevention of mortality" but I would have thought that should be the focus on the next steps.
It sounds like there hasn't been a correlation to the markers to the causes of death (which I would think would be pretty easy) and for things like cardio-pulmonary, cancer, diabetes and other diseases causing death then there should be approaches taken to avoid the expected deaths, resulting in longer lives and less expensive (to health care systems) disease treatments.
The Dutch scientists have some useful data, let's see it being used to prevent early deaths.
Re:Rather than Predicting how about Preventing Dea (Score:4, Insightful)
And it's not creepy, it's normal.
Treatable diseases (Score:2)
The publication's discussion goes in detail about the markers and their meaning.
A bunch of those are associated with treatable diseases such as Hypercholesterolemia, Diabetes Type 2, etc.
(other are more generic, such as inflammation markers).
You can see in a couple of years this publication being used as an argument to justify introduction of new public health policies for the ongoing efforts to better detect and treat the diseases.
(at least here around in our Evil Eurocommunist countries. In the US, your f
Obligatory Woody Allen Quote: (Score:5, Funny)
"I'm not afraid of dying, I just don't want to be there when it happens."
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Woody Allen Quotes on Death (Score:3)
There are quite a few:
- My relationship with death remains the same, I'm strongly against it.
- It is impossible to experience one's death objectively and still carry a tune.
- There are worse things in life than death. Have you ever spent an evening with an insurance salesman?
- Eternal nothingness is fine if you happen to be dressed for it.
- I don't believe in after life, but I am bringing a change of underwear.
- I don't want to achieve immortality through my work. I want to achieve it through not dying.
- Li
bullshit - worse than majority classifier (Score:4, Insightful)
Out of 7603 people, 1213 died. So if I just predict "you won't die", I'll be 84 % accurate. And similarly, I'll be less accurate for people over 60.
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Out of 7603 people, 1213 died. So if I just predict "you won't die", I'll be 84 % accurate. And similarly, I'll be less accurate for people over 60.
If you predict you won't die, that would make you dead wrong, not merely "less accurate". We humans are still batting 1000 when it comes to death, so let's not factor out the obvious.
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Out of 7603 people, 1213 died. So if I just predict "you won't die", I'll be 84 % accurate. And similarly, I'll be less accurate for people over 60.
Well I've never died once, so based on research I've done on myself in over 40 years of study, I must be immortal.
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If you predict "you won't die" you will be 0% accurate
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This is the most interesting graph from the study that in a way addresses your concern:
https://www.nature.com/article... [nature.com]
If I understand it correctly, the graph is a function of where you put the threshold for predicting death or not (which actually makes both axes into dependent variables).
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Found the cause (Score:5, Funny)
Of those Finns, 1,213 died during follow-up.
I would really suggest not going to those follow-ups.
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To quote Ricky Gervais again (Score:3)
"Being dead is like being stupid. It's only painful for the people around you."
I have that sort of accuracy ... (Score:2)
... without a bloodtest, just by looking at and watching people.
20% accuracy in predicting a 5-10 year window of death? Seriously?
Watch an old lady go and get a new hip, see her a year later with grey hair, an onset dementia and a general vibe of out-of-this-world and you know she's up soon on the gaunt mans list.
I bet dollars to doughnuts that any caretaker of old people has a higher accuracy that this testing thing some desknerd came up with.
My 2 cents.
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... without a bloodtest, just by looking at and watching people.
20% accuracy in predicting a 5-10 year window of death? Seriously?
Watch an old lady go and get a new hip, see her a year later with grey hair, an onset dementia and a general vibe of out-of-this-world and you know she's up soon on the gaunt mans list.
I bet dollars to doughnuts that any caretaker of old people has a higher accuracy that this testing thing some desknerd came up with.
My 2 cents.
Nurses and Nurses aids, health care people in general have that sort of accuracy.
Sick and twisted insurance tool (Score:3)
This will be abused by insurance companies to deny coverage for certain claims. Why would they bother "wasting" their money covering a critical surgery when the new magical blood test gimmick shows that you'll likely be dead in five years? (The obvious answer is they won't.
And given the accuracy isn't exactly in that 99% range, this is stupid, mean and downright dangerous to tell people this information. Consider your prediction is part of that 16% who were wrong in their analysis. Can you imagine the mental and psychological havoc that can easily manifest into real physical problems once a person is told their fate is sealed within the next decade? How many people might be sent off the mental deep end after being told they don't have much to live for because death is knocking on their door? Seems there's a lot of shit those sitting inside labs all day staring at Petri dishes don't think about.
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I agree that over-screening, especially without any explanation or contextualisation by medical professionals, is rarely a net positive. However...
Consider your prediction is part of that 16% who were wrong in their analysis. Can you imagine the mental and psychological havoc that can easily manifest into real physical problems once a person is told their fate is sealed within the next decade?
I did scan the full study but it was not immediately clear to me the difference between the false positive and the false negative %ages. Of course it's possible they were both 17%, but I'd guess that to be fairly unlikely. I'd also guess that different people would have varying opinions as to which is the worse situation, not being flagged as 'at risk' when you a
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This will be abused by insurance companies to deny coverage for certain claims. Why would they bother "wasting" their money covering a critical surgery when the new magical blood test gimmick shows that you'll likely be dead in five years?
To be fair, people might potentially want to know that. If you were considering a year of painful operations to fix a knee that would not fully fix mobility issues you might want to know if you are going to live 5 years or 50.
Voluntarily asking for this information, isn't even in the same league as insurance companies demanding it, or else.
I have no issues with the former. At all. I see major issues with the latter.
Sounds like an idea for a startup (Score:1)
Joke (not mine) (Score:2)
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That's scientifically proven to be the world's funniest joke, to the general population.
https://www.laughteronlineuniv... [laughteron...ersity.com]
Overselling (Score:1)
5-10 years. (Score:1)
So.... they guess a date and they consider it correct if you die in some 20 year range (+10 years -10 years of date picked). I wonder who wasted money on this pointless research.
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no, there is no minus. they didn't include dead people. It was those that would die in next 5 to 10 years. that is very useful, not just for prediction but to tell people to change their lifestyle as they will be in mortal danger if they don't shape up and do the right things.
IT Crowd has prior art (Score:1)
https://www.youtube.com/watch?... [youtube.com]
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Also: https://www.youtube.com/watch?... [youtube.com]
: )
Are any of the researchers named Pinero? (Score:2)
See subject.
Accuracy (Score:1)
"The accuracy DROPPED to about 72%"
does not look bad to me at all when forecasting life expectancy
Guessing Death (Score:2)
What to do (Score:2)
The factors are fats, sugar, and amino acids. All are adjustable by diet, supplementation, and in the worst case moderately priced medication.
I think that if you're knowledgeable enough in statistics (I'm not), you can infer optimum levels of these markers and modify your behavior accordingly. I wish the authors had presented the data in a way that made recommended levels obvious.
Is there somebody here on slashdot that can figure out those levels?
Heinlein was there first (Score:2)
https://www.baen.com/Chapters/... [baen.com]
Watch out for those insurance company death squads!
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Didn't Asimov do a version of this story, too? And there were probably versions before either or them.
At a higher level, I see the topic in terms of dying boots-on or boots-off. These days boots-on deaths are increasingly rare.