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Earth Science

An Amphibian Fungus Has Become 'The Most Deadly Pathogen Known To Science' 93

"On Thursday, 41 scientists published the first worldwide analysis of a fungal outbreak that's been wiping out frogs for decades," The New York Times reports. The outbreak has caused more than 500 species of amphibians to decline significantly (Warning: source may be paywalled; alternative source), making it "the most deadly pathogen known to science." From the report: Scientists first noticed in the 1970s that some frog populations were declining quickly; by the 1980s, some species appeared to be extinct. The losses were puzzling, because the frogs were living in pristine habitats, unharmed by pollution or deforestation. In the late 1990s, researchers discovered that frogs in both Australia and Panama were infected with a deadly fungus, which they named Batrachochytrium dendrobatidis -- Bd, for short. The fungus turned up in other countries, but studies of its DNA suggest that Bd originated on the Korean Peninsula. In Asia, amphibians seem impervious to Bd, but when it got to other parts of the world â" probably via the international trade in pet amphibians -- the pathogen reached hundreds of vulnerable species.

Amphibians are infected with Bd by contact with other animals or by spores floating in the water. The fungus invades skin cells and multiplies. An infected frog's skin will start to peel away as the animal grows sluggish. Before it dies, a frog may manage to hop its way to a new stream or pond, spreading the fungus further. The fungus thrives in cool, moist conditions. As a result, frogs that live in cloud forests on mountainsides have been hit particularly hard. Big frogs are at a greater risk, too, possibly because they don't multiply as quickly as small ones. [The lead author of the new study and his colleagues] identified 501 species in decline, far greater than the previous estimate of 200. Certain factors once thought to account for the decimation of frog populations -- like climate change and deforestation -- are not the greatest threats, the scientists found.
The study has been published in the journal Science.
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An Amphibian Fungus Has Become 'The Most Deadly Pathogen Known To Science'

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  • by MadTinfoilHatter ( 940931 ) on Friday March 29, 2019 @06:11AM (#58352528)
    Here is finally something you could introduce to get rid of those pesky cane toads! I foresee no problems whatsoever. :-)
  • by r2kordmaa ( 1163933 ) on Friday March 29, 2019 @06:32AM (#58352570)
    A pathogen that affects entire class of animals, wow, just wow. That's an equivalent of a disease that affected all mammals indiscriminately, I didn't think such a thing was possible.
    • Re:Wow (Score:5, Informative)

      by Gilgaron ( 575091 ) on Friday March 29, 2019 @07:28AM (#58352642)
      Fungi are bigger and more like us than viruses and bacteria are. So instead of being dependent on specific protein binding sites like a virus is, they can mechanically invade tissue like a parasitic worm could. They may have plant-like lifecycles but they have to find exogenous energy sources as animals do, so that's why so many consume detritus or are parasites.
      • Re:Wow (Score:5, Informative)

        by RockDoctor ( 15477 ) on Friday March 29, 2019 @10:28AM (#58353210) Journal
        Not sure if you're trying to play for laughs, but ... it's not just a question of individual protein binding sites for getting into a cell (as you say, is important for virii and some bacteria). In order to mechanically invade a tissue (e.g., skin - your biggest organ), an organism needs at some point to adhere one cell wall onto another from which it can get the anchorage to drive pseudopods or whole filaments into the structure.

        Different tissues have different adhesions proteins - that's how, for example, your eyelids can stick together but not stick to your eyeball - and the precise proteins vary from one species to another. But they do form families of related proteins, more closely related in more closely related species. (If I recall correctly, some of the first evidence that whales were more closely related to hippopotamuses than any other animals came from the proteins on the surfaces of their respective blood cells which would coagulate with each other. Yes, those troublesome blood groups are the result of adhesion proteins.)

        Oddly, it's a complicated subject. A few tens of thousands of species, each one with a few hundreds of relevant protein families, the mutual interactions of any with any being potentially significant.

    • This isn't killing all frogs, just ones that are susceptible. As the article stated:

      In Asia, amphibians seem impervious to Bd

    • Rabies [wikipedia.org] comes damned close!

    • A pathogen that affects entire class of animals, wow, just wow. That's an equivalent of a disease that affected all mammals indiscriminately, I didn't think such a thing was possible.

      Rabies...

      • Huh, never thought of rabies that way. But yes, you and kevmeister are right, rabies does affect pretty much all mammals. Thanks for pointing it out to me.
  • by DanDD ( 1857066 ) on Friday March 29, 2019 @07:04AM (#58352604)

    ... perhaps this pathogen can be engineered to infect only politicians.

    • The only problem with your plan is that political speciation is a Real Thing; you manage to erradicate all the politicians, more will spontaneously emerge from the rest of the population. It becomes a never-ending game of Whack-A-Mole -- at least until there are no more homo sapiens left.
  • https://www.youtube.com/watch?... [youtube.com] Megabrutal Fungus viral strategy. Maybe related ;-)
  • by Oswald McWeany ( 2428506 ) on Friday March 29, 2019 @07:44AM (#58352660)

    The spawning of this fungus has been toadaly out of control. We should always remember just how bad a pathogen can be to a species. Never froget about it.

  • by Anonymous Coward on Friday March 29, 2019 @09:16AM (#58352896)

    "probably via the international trade in pet amphibians"

    Who knows how many other diseases & invasive species gained access to whole (Western) World (& still do) because of international pet trade!!!
    & not to mention, how much of those pets get horrible treatment/suffering of all kinds!!!

    How about banning ALL INTERNATIONAL PET TRADE globally/completely/absolutely???

    • Yeah that'll work. Like banning all the international drug trade.
    • In most cases having an exotic pet is ok - but only if you're willing to keep it contained and destroy it when it's time.

      It's that last part that gets forgotten, however. They'd prefer to just "let 'em go", etc. They'll take their exotic turtle that's too big now and dump it in an irrigation ditch. No harm, no foul, right? That kind of stupidity usually works out (the animal doesn't survive out of its element), but not always. It played a role in burmese pythons getting into the Florida everglades. Two moro

  • by Anonymous Coward

    Isn't there some indication that the bees, bats, and frogs are all dying because of pesticides? The actual agent of destruction, in this case a fungus, taking advantage of a weakened immune system?

    • Even the summary says that its affecting frogs in pristine environment, with no pesticides and long before global warming was a real concern.

      • by Jzanu ( 668651 )
        Global warming has been a major concern since the 1800s and Svante Arrhenius [rsc.org] proved the heat trapping effect of carbon released by burning fossil fuel. Its accumulation as more fossil fuel is burned is well documented in later works [aip.org] by multiple other scientists.
  • the cure (Score:5, Insightful)

    by Anonymous Coward on Friday March 29, 2019 @10:33AM (#58353236)

    I thought they found a cure 4 years ago!

    https://phys.org/news/2015-11-chytrid-scientists-method-killer-fungus.html

  • I mean, other than the idiot teenagers and the anti-science supporters of the GOP, everyone knows that frogs and toads are the canary in the coal mine... and this means we are in seriously deep sh*t.

    Interesting question: any chance that this is someone's test gene editing gone horribly wrong?

    • by Alyks ( 798644 )

      I mean, other than the idiot teenagers and the anti-science supporters of the GOP, everyone knows that frogs and toads are the canary in the coal mine... and this means we are in seriously deep sh*t.

      I have no idea how true this is, but perhaps the climate and pollution, etc. not being as significant of factors as this disease means the idea that frogs are an indicator of environmental health isn't as true anymore?

  • At least not directly (we're probably transporting the fungus around the globe). That contradicts what I've heard said or implied in numerous documentaries and papers for decades - the top suspects were usually pesticides, or climate change, or habitat loss. It's interesting to go back to a 2008 slashdot article on the topic [slashdot.org] and see how many people jumped on the global warming and habitat loss bandwagon. The correct cause (the fungus) was even mentioned, but only modded up to a +4. Oh well, at least the

Somebody ought to cross ball point pens with coat hangers so that the pens will multiply instead of disappear.

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