Vaccines Can Help Fight the Rise of Drug-Resistant Microbes (harvard.edu) 103
An anonymous reader quotes the Harvard School of Public Health:
Drug-resistant strains of gonorrhea, salmonella, Escherichia coli (E. coli) and many other disease-causing agents are flourishing around the world, and the consequences are disastrous -- at least 700,000 people die globally as a result of antimicrobial resistance (AMR) annually, according to a 2016 review on antimicrobial resistance commissioned by former UK Prime Minister David Cameron. It's a perilous situation, but several new studies from researchers at Harvard T.H. Chan School of Public Health indicate that an important tool in the fight against AMR already exists: vaccines.
The Proceedings of the National Academy of Sciences recently devoted a special feature section to examine the role vaccines can play in stemming the tide of antimicrobial resistance. In general terms, vaccinations can help lessen the burden in two ways: First, they can protect against the direct transmission of drug-resistant infections. Second, they can lessen the chances of someone getting sick, which in turn reduces the likelihood that he or she will be prescribed antibiotics or other medications. The fewer medications someone takes, the less likely it is that microbes will evolve resistance to the drugs.
The Proceedings of the National Academy of Sciences recently devoted a special feature section to examine the role vaccines can play in stemming the tide of antimicrobial resistance. In general terms, vaccinations can help lessen the burden in two ways: First, they can protect against the direct transmission of drug-resistant infections. Second, they can lessen the chances of someone getting sick, which in turn reduces the likelihood that he or she will be prescribed antibiotics or other medications. The fewer medications someone takes, the less likely it is that microbes will evolve resistance to the drugs.
Re: not shilling for big pharma (Score:1)
No one has ever said vaccines are perfectly safe. However the risk vs reward is near 100%. I would rather risk (although it is proven bullshit) my kid have a 1 in 50000 chance of autism than a 50/50 shot at a real disease like measles that kills and is now re-entering our population through 2 routes: the open southern border and anti-vax morons who do not give their kids shots.
Someone I know from work was an anti-vax idiot. He talked about it all the time. Then he married his pregnant illegal alien Mexi
Re: not shilling for big pharma (Score:2)
People say vaccines are perfectly safe all the time and call anyone who questions that batshit stupid. I had at least one someone reply to me saying exactly that last week here in Slashdot.
Even if you know someone injured by a vaccine and/or someone who received a payout from the secret vaccine court you're still batshit.
Anytime a narrative over powers reality the narrative needs questioning, and this narrative is super powerful.
My suggestion to restoring trust:. Do away with the secret court and government
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Is this the secret court you are talking about? The one advertised the HRSA web site? https://www.hrsa.gov/vaccine-c... [hrsa.gov]
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It's called a secret court because what happens in the court itself are secret, not the existence of the court itself.
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Don't believe the conspiracy theories. Vaccines aren't perfectly safe: any treatment has the potential for adverse reactions. Vaccine side effects are VERY well monitored. Reporting is legally required, and the data is public.
https://www.cdc.gov/vaccinesaf... [cdc.gov]
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I happen to be very close to more than one person who works in the pharmaceutical industry, or has at one point in time or another.
When a vaccine industry gets reported it's like pulling teeth to get a report filed. When a person lower on the pole tries to make it happen, they're more often than not blocked by someone higher up. Reporting vaccine injuries is considered "bad behavior" by at least one very large and very recognizable chain.
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Perhaps your "friend" in the pharma industry is fibbing. Adverse reaction reporting is done by treating physicians, and is taken very seriously. The US has a problem with pharma, money and physicians, but there's a lot less payola in vaccines.
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Pharmacies give vaccines now. In fact if there's a pharmacy near you getting close to flu season the icon on Waze says "Flu Shot". A pharmacist is not a physician, and there's more than just flu shots done at pharmacies, they practically beg the elderly to get shingles shots at the checkout counter.
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'Measles was a minor annoyance illness for thousands of years before anyone invented a vaccine. It's just not that bad.'
You're an idiot or you're Jenny McCarthy.
"In 2011, the WHO estimated that there were about 158,000 deaths caused by measles. This is down from 630,000 deaths in 1990.[4] "
https://en.wikipedia.org/wiki/... [wikipedia.org]
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You are almost entirely incorrect.
I had chickenpox twice when I was a child. My first case was so mild that my immune system did not maintain antibodies for it. My second case was more severe and my immunity to chicken pox has persisted. Yes, antibodies developed by vaccines can wear off, but so can antibodies developed by normal infections. Also, shingles is just a reemergence of the same chickenpox virus that most adults contracted as children. The virus hides in the nervous system and reemerges as p
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"There is NO RISK WHATSOEVER. All the cases of autism and other iatrogenic diseases caused by vaccines are FAKE NEWS."
Shut up, Jenny McCarthy.
vax sounds like tech salvation (Score:3)
Better start rebuilding our soil...
Sort of skeptical of this (Score:5, Informative)
There has been what some might consider an exhaustive effort to develop numerous bacterial vaccines for cows to mitigate episodes of bovine mastitis and the only one that has been moderately successful is the J-5 E. coli vaccine. There are 4 to 5 other species of bacteria that can cause bovine mastitis and vaccines against those other species haven't been successful in the last 20 years.
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I wonder how much of that is just because antibiotics are more convenient. There wasn't much progress on an ebola vaccine either, until a whole bunch of people got it.
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Back when I was a kid, they taught us that vaccines against bacteria were impossible. It isn't a convenience thing; bacterial vaccines are a lot harder to develop. You can't just use a weakened or inactivated bacteria like you can for viruses, because the immune system won't ever react to it at all without the presence of some other threat.
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I'm perhaps a bit younger, since I received several actual anti-bacterial vaccines as a child. You can actually make vaccines using either attenuated live (e.g. tuberculosis, typhoid) or killed (older typhoid, pertussis) bacteria. As you mention, you can also make vaccines to the toxins, although that might be less acceptable for livestock due to the risk of the bacteria being transmitted to a person who isn't vaccinated.
It does seem to be more difficult to create fully effective vaccines for bacteria, part
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Oh, yeah. I guess that's true, I did get the DPT vaccination. I guess I'm remembering
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I expect that such a ban, perhaps also requiring a certified vet to prescribe antibiotics, would spur vaccine research. It might actually not be possible, but there's not much motivation when antibiotics for livestock costs pennies.
What the hell slashdot (Score:2, Insightful)
I had to wait 90 seconds for slashdot to load dozens of advertising trackers [imgur.com].
I guess this marks my departure from Slashdot. This is a sign of what will become the world wide web for the rest of our future. We had a chance to make a difference and the same dichotomies of change that prevented TV from being a learning medium will prevent the internet from reaching it's true intent. Or in less savage terms, the golden era of the internet has already passed and like traveling before 9/11, no one will remembe
vaccines are our best bet on all microbes (Score:5, Interesting)
This is why at some point, we really need to REQUIRE vaccines for all. At the least, require that unvaccinated be removed from ALL schools except for home schooling, and if they catch a disease, they have to pay for everything.
Not close enough it would seem (Score:1)
You have been attempting to impersonate me a fair bit recently. But the writing style is not at all similar to mine.
The only people you will convince are gullible fools. Since that seems to be the demographic you and WindBourne are targeting anyway, go right ahead. WindBourne has already been caught out using this exact same tactic before, so your credibility cant get any worse.
Just for the record, Where did I say WindBourne was a climate denier? I never did.
You will have to do your homework a bit bette
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You are a constant liar. Here is just a few examples. [slashdot.org] You claim all the time that I am a denier of America's pollution as well as Global. Yet, I have never ONCE done that. I DO say that America has been headed in the right direction for the last 10 years (save 2018), while CHina is the exact opposite. Even in 2018, we were headed in the right direction, EXCEPT for nat. gas for electricity. That has to stop and we need geo-thermal, al
Go fuck yourself WindBourne (Score:2)
WindBourne's Secret Admirer will definitely pop up again sooner rather than later. He/she/it actually thinks he's/she's/it's helping your cause by showing the kinds of kooks that you attract.
You deny constantly that American people are worse than Chinese people when it comes to CO2.
You deny that historically America is the biggest source of CO2.
You constantly play down the reality that America per person is still over twice as bad as Chinese people. You try to convince everyone that because they got a li
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Or we could just stop putting antibiotics into everything everywhere creating the resistance.
microbes don't just adapt, they also fight each other for space and when you wipe out one colony type you also reduce the threat against those of a different type. the microbiome in the gut is a great example of things like this. Even the once thought to be vestigial appendix has a use discovered for it now as a safe-house for beneficial bacteria.
creating a vaccine for something serious like measles is great, crea
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That would be extremely rare though: https://microbialmenagerie.com... [microbialmenagerie.com]
And even if it would happen it would happen anyway as your body would create the very same antibodies once you get exposed to the decease as your be from being vaccinated for the same decease.
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With that said, bugs do not become resistant to vaccines. What happens is that some bugs, mostly virus, undergoes antigenic shift. Basically, the markers on the various bugs that antibodies react to, will change shape (or simply disappear). A great example of this
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Right after we re-criminalize sodomy ... careful about praying for tyranny.
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O requiring wearing seat belts and having air bags. Horrible.
OR, requiring that ppl who are put under quarantine because they have any number of highly infectious diseases to remain in their homes, again, is a horrible thing.
I am guessing that you are not old enough to have witnessed any of these diseases. The last case of small pox in America was before I was born in 59.
However, I have known ppl with Polio. Likewis
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By forcing sodomy underground you severely restrict the promiscuity of men who have sex with men. They are on average carriers of highly infectious diseases in combination with their lifestyle.
So as I said, be careful about praying for tyranny ... it won't always hit who you personally want.
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Nearly all microbes adapt to antibiotics. The reason is that after enough usage 1 of them will develop a resistance to the antibiotic. Then the resistance is normally passed around to others, typically via plasmid. So, just for fun, assume that it takes on average 1T instances of being exposed prior to resistance. If you have stimulated the body to fight the AMR, then we do not have to use antibiotic except for extreme cases.
Well, maybe. Or you may have stimulated the body so much that it doesn't respond to anything as aggressively as it should, and the person ends up not being able to fight off even the less extreme stuff, or worse, responds too often and starts attacking the person's own cells (autoimmune disorders). The more things you vaccinate against, the greater that risk.
I'm absolutely in favor of vaccinating for deadly viral diseases that are highly contagious, but the moment you start to demand mass immunization for
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Basically, what you are suggesting is that vaccinations cause autoimmune. Yet, logically, that makes little sense.
We already know that viruses and bacteria DO cause autoimmune. GBS is a great example of one.
The notion that vaccines don’t cause autoimmunity makes sense. Since vaccines don't drive the immune response nearly as vigorously as natural infections do, it is less likely that they would induce autoimmunity. However, scientists continue to study questions related to vaccines as a ca [chop.edu]
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No, that's not at all what I'm suggesting. Current vaccines do not (or at least are not known to) cause autoimmune disorders, although vaccinations can trigger preexisting autoimmune conditions.
As far as I'm aware, nobody knows exactly what actually causes autoimmune conditions to begin with, beyond that the immune system somehow gets confused about what it should attack. My best guess is that
Corporate farms (Score:1)
These kinds of problems (rampant disease in cattle) seem to affect mostly cows crammed into unclean and unsanitary conditions.
Maybe they don't need a vaccine at all, but better animal husbandry. But I guess common sense and decency will never win out against greed.
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In places like China, they avoid vaccinating many of their animals and then hope that they will not get sick, but if they do, they simply use the cheap stolon antibiotic. Of course, that is what gives us antibiotic resistant microbes.
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That's not entirely true. There are different kinds of vaccines. An organism could develop resistance to a vaccine consisting of viral or bacterial particles.
Health (Score:1)