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Medicine The Internet

Dark Web Dealers Voluntarily Ban Deadly Fentanyl (theguardian.com) 158

Major dark web drug suppliers have started to voluntarily ban the synthetic opioid fentanyl because it is too dangerous. "They are 'delisting' the high-strength painkiller, effectively classifying it alongside mass-casualty firearms and explosives as commodities that are considered too high-risk to trade," reports The Guardian. From the report: Vince O'Brien, one of the NCA's leads on drugs, told the Observer that dark web marketplace operators appeared to have made a commercial decision, because selling a drug that could lead to fatalities was more likely to prompt attention from police. It is the first known instance of these types of operators moving to effectively ban a drug.

O'Brien said: "If they've got people selling very high-risk commodities then it's going to increase the risk to them. There are marketplaces that will not accept listings for weapons and explosives -- those are the ones that will not accept listings for fentanyl. Clearly, law enforcement would prioritize the supply of weapons, explosives and fentanyl over, for example, class C drugs -- and that might well be why they do this. "There are also drug users on the dark web who say on forums that they don't think it's right that people are selling fentanyl because it is dangerous and kills a lot of people."

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Dark Web Dealers Voluntarily Ban Deadly Fentanyl

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  • by Anonymous Coward
    For things too bad for the regular darkweb. I heard it's behind 7 proxies.
    • Time for an infra-black web, which you can only see by lowering your head and running hubwards into your monitor.
    • by Anonymous Coward

      To be fair, most of what the media calls "the dark web" is more accurately the "gray web" or maybe the "underground web." Most of it is pretty easy to find with a minimum of effort, and there are search engines which do index it. Contrast that to actual dark networks, which are not indexed and not easily accessible at all.

  • by An Ominous Cow Erred ( 28892 ) on Sunday December 02, 2018 @12:37PM (#57736840)

    Fentanyl actually has a fairly wide therapeutic index -- i.e. the dose that offers benefit vs. the dose that causes harm -- so it's fairly safe (at least as safe as a highly-addictive opioid can be) as far as prescription drugs go. IIRC acetaminophen (Tylenol) is actually easier to OD on. The problem is potency and the fact that pill pressers are buying pure fentanyl and trying to meter out the microscopic doses using crude tools.

    It's easy to measure grams of a substance, so if 1 gram gets you high but 10 gram kills you, it's not hard to press out 1 gram pills and tell people to never take more than 3 of them.

    Now imagine 1 microgram gets you high and 100 micrograms kills you. In terms of therapeutic index, it's actually 10 times safer. If you could reliably press out 1 microgram pills, nobody would ever accidentally OD on 100 pills. The problem is that joe schmoe pill pusher in his basement cannot accurately separate out 1 microgram of a pure substance, so he wants up cranking out pills that have anywhere from 3-50 micrograms of ingredients. You wind up with a bunch of pills where 2 of them might get you nicely really really high, but then another 2 will randomly kill you. Couple that with some people having high tolerance due to longtime use while other people are just starting out, one pill might be enough to kill a first time user if they're unlucky enough to get that one where joe pill pusher's hands slipped when he was pressing it.

    The solution would be for the labs producing the stuff to only sell it in dilutions of 0.1% or so, but the market doesn't want that because mr. fentanyl smuggler only has to get one shipment from China through customs to make a million pills if he brings in the pure stuff. This is actually fentanyl's awesome market-winning feature -- its potency minimizes the smuggling risk, and this is why it's taken over the market from heroin in the U.S. for low-budget opioid addicts.

    Of course the real truth of the matter is that opioid addiction is a fucking curse and the best thing to do is never ever start, but unfortunately big pharma likes it profits and creates tons of future fentanyl users every time it writes a new painkiller prescription. Next time your doctor considers writing you a scrip for some of the good stuff -- say sorry, I'll just take an aspirin and maybe smoke some weed.

    • by Anonymous Coward

      Excellent point on therapeutic index.

      As an addendum to your dilution point, if you can't measure accurately at small scale, dilute it or cut it with something else, then measure at a larger scale where mistakes aren't as punishing. If you don't want an ultimately cut product, dissolve it in a solvent, then evaporate off the solvent, preferably recovering it for recycling.

      • by An Ominous Cow Erred ( 28892 ) on Sunday December 02, 2018 @12:51PM (#57736912)

        You're expecting responsible behavior and the maintenance of large quantities of dilute with strict quality control from some guy with unknown education working in a basement somewhere with no oversight, and a customer base that literally cannot say no.

        He almost certainly doesn't *want* to kill his customers, but that doesn't mean he has the know-how and discipline to do a good job of it, and the shadowy nature of the job means you can't just go by yelp reviews.

        • by Anonymous Coward

          Actually, a documentary on the opioid crisis suggested that intentionally adding relatively cheap carfentanyl (rhino/elephant tranquilizer, more powerful that fentanyl) to heroin is explicitly done *for the purpose of killing customers* as a manner of advertising that a dealer's dope is not cut with less-expensive inactive ingredients. Perverse incentives are at play for both the supply and demand sides of this market.

          CAPTCHA: entice

        • Re: (Score:3, Interesting)

          by GameboyRMH ( 1153867 )

          Sometimes they do want to kill a customer, as an advertising tactic. They intentionally slip a fatal dose of fentanyl into some heroin for example, and sell it to a customer they can afford to lose. This death sends up a beacon, making other junkies think that this dealer has "the good stuff" on the assumption that it was purity/potency that caused the overdose and not intentional contamination.

      • by guruevi ( 827432 )

        Therapeutics like these can't be diluted and subsequently recovered 'easily'. Hence why so many backyard drug producers end up killing themselves or blowing themselves up.

        It's not 'hard' to buy the right stuff to measure correctly (you can buy them used for $1k, new for $10k), there is no controls or government watchdog to get the tools. Even the drugs themselves are relatively easy to obtain and 'lose' if you know the right connections and circumstances. But if you're smart enough to run an entire professi

      • by Hognoxious ( 631665 ) on Sunday December 02, 2018 @05:26PM (#57737876) Homepage Journal

        That relies on the active ingredient being evenly distributed in the inert carrier, i.e. perfect mixing.

        • Perfect solid mixing is practically impossible with non-professional equipment. It starts with requiring all grains to be far smaller than the lethal dose, and no accumulation in layers, nooks of the apparatus, etc. Liquid mixing is better, but also more complicated on second sight - i.e. you should use a clean room to exclude dust particles which could selectively adsorb the active substance in lethal concentration, and then end up in the pill. Not exactly the type of set-up you would expect in a backyard

    • by Actually, I do RTFA ( 1058596 ) on Sunday December 02, 2018 @12:59PM (#57736938)

      The problem with Fentanyl isn't Fentanyl pills... it's Fentanyl spiked heroin/whatever. Cause that lets them cut the underlying drug more. So, you have heroin of unknown quality and it's too strong.

      Part of it is the various tolerances, but a bigger problem is the difficultly measuring (as you point out) and evenly mixing the Fentanyl into the drug. Also, it's so damn potent that trying to clean up drugs left behind by addicts, even with gloves, can aerosolize enough to kill people. Like cops or bereaved parents.

      A big part of the solution is Fentanyl testing kits for illegal drugs, to prove they are pure.

      • Drug-detection kits should be sold in every drugstore, but that's not going to happen as it would be seen as somehow "enabling" drug use. The only detection kits the government will ever support over-the-counter are the kind that detect it only after a person has consumed them (i.e. too late to save the user, but good for persecution/prosecution of the user).

      • by Luckyo ( 1726890 )

        So enable every neighbourhood kid to be a Fentanyl pusher when his dad loses his job. That's going to help things.

        Have you ever read about Opium Wars and what opiates that are freely available do to a nation? There's a reason why China is the key supplier of this stuff. They know from first hand experience how large nations are undermined. And it's in their geopolitical interest to have Western majors to implode on themselves just like China imploded on itself due to opium in 1800s.

        • The Chinese are nuts if they think half the labs production isn't going out the side door for domestic use.

          • by Luckyo ( 1726890 )

            They know. That's why anyone who does this stuff and gets caught gets the noose. Chinese don't fuck around with drugs and drug pushers that don't toe the party line.

    • where the effect becomes stronger with dilution [wikipedia.org], so you can easily accidentally kill your patient when re-using any equipment that came into contact with some substance before.

      Ok, just joking here, Homeopathy is fraudulent quackery, and of course there is no such thing as increasing effect with increasing dilution.
    • The potency is definitely a large part of the commercial appeal of fentanyl analogs - similar to the way beer gave way to liquor during prohibition - but I'd argue that an even bigger driver is that it's fully synthetic. Heroin, oxycodone, hydrocodone, etc. all rely on access to large quantities of poppy straw. Combine that with the proliferation of grey market Chinese and Indian labs and you've literally got a recipe for disaster.

      There could be a time in the near future where it will be possible to "hom
    • by demonlapin ( 527802 ) on Sunday December 02, 2018 @05:32PM (#57737904) Homepage Journal
      Fentanyl is a terrible substance. It has its uses, but they are very limited. It's an extremely short-acting drug, so it doesn't provide good long-term pain relief unless used in a patch, in which case why not use extended-release morphine? It's really good for the induction of anesthesia, because it blunts the painful process of being intubated but doesn't last so long that it keeps you from breathing at the end of the case. Other than that, I don't use it on my patients, and I'm an anesthesiologist.

      Dilution isn't a bad idea, and it's what we do - hospital fentanyl comes in 50 mcg/mL, so for one gram of solution you have 50 mcg of agent. 0.005%. Easy to fuck it up, or make it uneven. Even if you recrystallize it yourself to get clean product... it's risky as hell. I'd pump myself full of naloxone (opioid antagonist) before I'd even consider working with the powdered drug unless it was in a fully sealed drybox or similar.

      I knew one guy who used to shoot fentanyl - the hospital-grade, known-strength stuff. He'd start an IV on himself. He'd then squirt a vial of naloxone into a small bag of saline, and hook that up to the IV. Then he would pinch it off and shoot up. If he passed out, the naloxone would start flowing, and he'd come back to life... that's roughly the level of precaution required when you know exactly what you're getting.
    • by gweihir ( 88907 )

      There is also the problem of newbies that want to get rich quick and have no clue how things work. These may sell ODs simply because they are clueless.

    • by pjt33 ( 739471 )

      Most of your post was informative and interesting, so thank you for that. But I disagree with the conclusion in the last paragraph. I learnt the hard way about 15 years ago that if you refuse to take strong enough painkillers for chronic pain the result is nerve sensitisation which means that the pain can continue for months after the root cause has healed. I'm currently being treated for a different chronic pain, and because of my previous experience I didn't hesitate when my doctor prescribed tramadol. Ho

    • So you are saying someone else is reaping the harvest of big pharma. I'm sure big-pharma must be upset. They should find ways to write more n more stronger prescriptions and also ensure the law department does their job so the revenue stream keeps flowing-in and not to some poor smuggler.
    • Acetaminophen/Tylenol/Paracetamol is NOT easier to overdose on.

      Fentanyl [drugbank.ca] has an LD of 3.1 mg/kg in rats, and 0.03 mg/kg in monkeys.
      Tylenol [drugbank.ca] has an LD of 338 mg/kg in mice (oral); 1944 mg/kg in rats (oral).

      I.e. It is much easier to OD on fentanyl. BUT... and this is the part people don't IIRC...

      There ARE more OD's on tylenol than on fentanyl... primarily cause it is so common and cause a lot of those happen with small children, due to their weight ratios being more favorable for an overdose.
      BUT... and it's a b

  • by Anonymous Coward

    The dark web doesn't have such a large economy because there is so many "evildoers" in the world, they are so large because tyrannical governments do things like make a wonderfully fragrant flower that grows with very little effort in very little time under almost any conditions out to be some sort of demon weed that must be eradicated.

    Gangs only exist as a response to the fascist pig gang in blue.

    The pigs wanna play war, and so, by government force, they get one.

    captcha: antibody

  • We're not dealing in fentanyl any more, honest!
  • It makes sense... (Score:5, Interesting)

    by SvnLyrBrto ( 62138 ) on Sunday December 02, 2018 @01:13PM (#57736972)

    Drug dealers are not, by preference, killers. They're business owners. And they don't want corpses. They want repeat customers. And you can't go back for more if you're dead from an overdose.

  • So they're doing it, not because it harms people, but because it's too risky for them. Well aren't they special?
  • The dealers are only looking out for their business model, nothing more. They have come to realize that dead users doth not repeat customers make.

    This will sound cold but I have a hard time generating any sympathy for those who OD on opioids or any drug tbh.

    If you're dumb enough to trust a substance purchased in a back alley or street corner from your local model citizen drug dealer, well. . . . Darwin has a law you should familiarize yourself with.

    Even legitimate drugs have their risks and, if you bother

    • So, you don't understand probabilities. Because you listed a bunch of "potential side effects". But if those happen 1 in a billion times, and they solve a real problem (fix a condition that makes your life miserable, or just cuts your risk of heart attack in half) it's more than worth it. By focusing solely on possibilities, and not probabilities, you're making your life worse.

      You also have no idea how the drug crisis started. People didn't start with heroin. Most times, they got addicted to oxy or som

  • Their customer base is shrinking due to deaths. They don't have consciences, they have business reasons only.
  • That's really sweet of them.

"The whole problem with the world is that fools and fanatics are always so certain of themselves, but wiser people so full of doubts." -- Bertrand Russell

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