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Medicine Science Technology

An Artificial Womb Successfully Grew Baby Sheep -- and Humans Could Be Next (theverge.com) 188

An anonymous reader quotes a report from The Verge: Inside what look like oversized ziplock bags strewn with tubes of blood and fluid, eight fetal lambs continued to develop -- much like they would have inside their mothers. Over four weeks, their lungs and brains grew, they sprouted wool, opened their eyes, wriggled around, and learned to swallow, according to a new study that takes the first step toward an artificial womb. One day, this device could help to bring premature human babies to term outside the uterus -- but right now, it has only been tested on sheep. The Biobag may not look much like a womb, but it contains the same key parts: a clear plastic bag that encloses the fetal lamb and protects it from the outside world, like the uterus would; an electrolyte solution that bathes the lamb similarly to the amniotic fluid in the uterus; and a way for the fetus to circulate its blood and exchange carbon dioxide for oxygen. Flake and his colleagues published their results today in the journal Nature Communications.
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An Artificial Womb Successfully Grew Baby Sheep -- and Humans Could Be Next

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  • Bene Tleilax, here we come!
    • Re: Axolotl Tanks! (Score:2, Informative)

      by Anonymous Coward

      Those tanks were the exact opposite of those artifical wombs though.

    • by zlives ( 2009072 )

      yes once the demand is so great that when the butlerian jihad happens the demand must result in the creation of Axolotl tanks... a bit of a stretch but i like where this is going.

  • Brave New World (Score:5, Insightful)

    by chromaexcursion ( 2047080 ) on Tuesday April 25, 2017 @10:43PM (#54302867)
    Read the book.
    too many implications.
    • by Hartree ( 191324 )

      Quiet, or I'll put alcohol in your blood surrogate.

    • You think that babies being born out of the womb was the problem with the society in "Brave New World?"

      Might I suggest you read the cliffs notes for "Brave New World" instead?
      • by HiThere ( 15173 )

        Babies being born artificially wasn't the only problem, but it was the enabler for the other problems.

  • by markdavis ( 642305 ) on Tuesday April 25, 2017 @10:45PM (#54302879)

    Since many women feel free to just go to a sperm bank and have a child without a "father" [through artificial insemination], men will eventually be able to go to an egg bank and have a child without a "mother" [by renting an artificial womb].

    Of course that is not the primary drive behind the development, but there are so many possibilities. Women with hysterectomies banking eggs to have children later without the risk and complexity of a surrogate. Husbands having children from eggs extracted from their dead or dying wife. Gay couples having children without involving any women. Old couples changing their mind about having children (as long as they planned ahead). "Professional" women who don't want to ruin their jobs or be inconvenienced. Attractive women who don't want to ruin their figures. Governments producing children using extracted DNA.

    • by TWX ( 665546 )

      Just be pragmatic, there are lots of medical conditions that can cause women to be unable to conceive or unable to carry a child to term. Infertility is already treated for to attempt to counteract these conditions but there are still conditions that are not effective.

      This kind of procedure can be used to allow women that suffer from these kinds of conditions to have children. It can allow women that work in risky occupations to have healthy children. It could even allow women that have health issues unr

      • by rtb61 ( 674572 )

        I still try to understand for what reason should genetic faults be artificially reproduced on purpose, for no other reason than to feed the ego of the holder of those defective genes. If you are genetically incapable of producing children why should you genes be pushed onto the next generation, who in turn will be genetically incapable of producing children but then ego must be served in a society based around narcissism from the top.

        • by TWX ( 665546 )

          It's very simple. Not all reproductive faults are genetic in origin. Some are due to injury, some are due to medications that the person's own mother took prior-to or during pregnancy. Some are due to environmental factors.

          Additionally not all genetic faults are passed-on either. There are already ways to test in-utero for faults. Among them is a test called Progenity that allows one to screen for Trisomy and a whole slew of other conditions, where the only sampling needed is a blood-draw from the moth

    • Re: (Score:2, Troll)

      by lucasnate1 ( 4682951 )

      Feminists will resist this, because it will reduce their bargaining power.

      • As they want to ban prostitution, for the same reasons also
    • Imagine future generations of womankind growing up in a world where women are no longer needed for making children except for their eggs. This is a first step toward that. And that's not the end of the world for women. It's more like the end of the beginning.

      Look at how dishwashers and vacuum cleaners worked out - did women think that was the end of the world because so-called "women's work" was in part automated? Noep, noep, and absolutely noep, it freed women to do other things. Patriarchal boneheads at t

      • by flink ( 18449 )

        The artificial womb will free women from the expectation of motherhood in order to perpetuate the species. markdavis's remark about women being able to build up their professional life without worrying about missing out on motherhood will be just the first symptom of this liberating technology.

        That is only the case if your definition of motherhood begins at conception and ends at delivery. Your life as a parent is just starting at that moment. If you asked my wife, she will definitely say she is more comfortable now, but in terms of time, energy, and resources, our kids definitely consume more of all three outside the womb than in it.

        You could envision some far future society where sperm and egg are decanted from banks, brought to term in artificial wombs, and raised in creches to adulthood by

      • by HiThere ( 15173 )

        FWIW there's already work in progress towards taking a skin cell (a *live* skin cell, not one from the surface) and converting it into a root stem cell. And lots of work on taking that stem cell and causing it to develop into any particular kind of cell desired. In this case that would be an oocyte. Then there will need to be work done on maturing and supporting that oocyte, but that's probably not major considering what's already been done. And sperm is even easier.

        So there won't be a need for either m

    • Not yet. There's still a significant window where babies can't be supported out of the womb. This would be useful for early premature born babies, born months early, not from conception on. Doctors have been pushing back how early a baby can be born and still survive for a while now.

      Scientists have recently also had breakthroughs on the other side of things, keeping embryos alive from IVF longer without implanting them [sciencemag.org], but that was pushing it forward a matter of days, not say into the second trimester.
  • by Gravis Zero ( 934156 ) on Tuesday April 25, 2017 @11:03PM (#54302981)

    Veal is about to get a whole lot fresher! ;)

  • by hyades1 ( 1149581 ) <hyades1@hotmail.com> on Tuesday April 25, 2017 @11:13PM (#54303025)

    I have no doubt that in countries where abortion is legal, right-to-lifers will be lining up to crowd-fund this research, and to pay for women who would otherwise have an abortion to pop their fetuses into these artificial wombs and brought to term.

    And then, of course, they will act boldly to ensure that the fetuses are adopted into loving families...perhaps even their own!

    Yeah, right.

    • by xvan ( 2935999 ) on Tuesday April 25, 2017 @11:30PM (#54303081)
      There is actually more demand than supply for healthy babies (under 3yo). The issues are laws and state regulations.
      • Isn't it astonishing that the RTL'ers haven't been lobbying to streamline those regulations!

        • by mentil ( 1748130 )

          If it doesn't take a year of red tape, and $25k, then the *shock* plebeians could adopt! Won't someone please think of the children?!
          Seriously though, eliminating the requirement that a couple must be married in order to adopt is a regulation the family-values GOP will never strike down.

          • by mentil ( 1748130 )

            Just noticed you said RTL and not GOP. Oh well, there's enough overlap that it's close enough.

          • by DarkOx ( 621550 )

            What state are you in? I live in Virginia and I know a couple single people that have been allowed to adopt. I know more that have been foster parents.

          • And unofficially, amongst conservatives, the marriage in question had better include two (and only two) people, and there had better be one from each of the traditional two sexes, or the application is going to encounter a lot of unfortunate "accidental" difficulties.

        • No one cares about Right To Life. What people are is "pro birth". If they cared about RTL then there wouldn't be complaints about life saving abortions.

          • If they really cared about eliminating abortion, they'd be embracing contraception for everyone. Instead most of the organisations that oppose abortion also lobby against contraceptive education programs, against mandatory insurance coverage, and against government-provided or -subsidised contraception for the low income.

          • Once the fetus transition into actual infancy by emerging from the womb, they couldn't care less what happens to it.

    • I have no doubt that in countries where abortion is legal, right-to-lifers will be lining up to crowd-fund this research, and to pay for women who would otherwise have an abortion to pop their fetuses into these artificial wombs and brought to term.

      And then, of course, they will act boldly to ensure that the fetuses are adopted into loving families...perhaps even their own!

      Yeah, right.

      OTH, the same people will lose their shit when they realize gay and lesbian couples will be able to have their own babies in a buy-an-egg-or-sperm kind of a thing. This will fundamentally change the nature of reproduction (and thus marriage). And then the Anti-Christ will come or something. Oh, I can see the shows in the 700 Club.

  • by SuperKendall ( 25149 ) on Tuesday April 25, 2017 @11:26PM (#54303071)

    *Should* humans be used to bring sheep fetuses to term, or should they continue using the artificial wombs?

  • for the win. Too obscure?
  • "The ocean's dying. Plankton's dying. It's sheeple! Soylent Yean is made out of sheeple!!!"

  • Immunity (Score:4, Insightful)

    by sheramil ( 921315 ) on Tuesday April 25, 2017 @11:46PM (#54303151)
    It is my limited understanding that the offspring gets part of their basic immune system from the mother while in utero. I didn't see any mention of where these lambs got theirs, if they have any.

    If they're going to spend their brief lives in a steel box before being prepped for someone else's dinner, I guess an immune system doesn't matter that much.

    • by dbIII ( 701233 )

      It is my limited understanding that the offspring gets part of their basic immune system from the mother while in utero

      Since this is the final stage instead of the entire term it's possible that step has been passed. If not it's another of many problems to be solved.

      • by HiThere ( 15173 )

        It's my understanding that the immunity transfer mainly happens in the later stages, and much of it even post-natal (via suckling). So much of it is already being frequently bypassed with sub-optimal results. But kids usually survive.

        That said, this would appear to worsen the situation, so it does appear to be another problem to be solved.

        • by dbIII ( 701233 )
          Perhaps you should look at it as the updated version of a humidicrib that it is instead of what the headline is pretending it is.
          • by HiThere ( 15173 )

            But I'd prefer to look at it as the next step towards an artificial womb that can raise an oocyte to an infant. Your view is more accurate for the current version, but the developmental vector is towards the other view. If we're guessing future consequences, then the current version is less important than the fully developed version. Of course, if one is trying to guess the timeline, then a current accurate measurement is more important...but I suspect that even were I to read the original article they'd

  • That's like a scene from every alien horror flick...
  • by chuckugly ( 2030942 ) on Wednesday April 26, 2017 @12:03AM (#54303199)
    So if this is made to work for humans will it make abortion obsolete?
    • Yes, no, and maybe.

      If your support for abortion is purely about a woman's right to make decisions about her body, then yes.

      If your objection to abortion is based on the view that a fetus, at whatever arbitrary stage, is a human then I expect it wouldn't change anything for you.

      • If the arguments you list both for and against are taken to truly be as they seem at face value then the ability to extract the fetus from the woman's body (her body, her choice) and not kill it (it's a human and has a right to live) would seem to satisfy both sides. I strongly suspect that neither side is actually basing their positions on the stated argument, which is why I raised the question. Instead I suspect the pro-life side is against casual sex and the pro-choice side are more interested in a woman
  • by Traf-O-Data-Hater ( 858971 ) on Wednesday April 26, 2017 @12:09AM (#54303213)
    ...there is an observation port built into the device.

    Then it would be a womb with a view.
  • by rickyslashdot ( 2870609 ) on Wednesday April 26, 2017 @12:37AM (#54303281)

    Jeez, get a grip - and READ THE ARTICLE.

    The apparatus did NOT 'grow' a sheep, it merely kept a premature sheep embryo alive long enough to separate it from the device, and then have it submitted to the knife of the 'scientists' so they could evaluate the effectiveness of the artificial womb.

    OK, I am NOT anti-science, and I really do appreciate the accomplishments of this endeavor - - - therefore there is NO reason to blow the accomplishments out of proportion.

    THIS 'device' is being put forward as a means to extend the viability of really early premature birth infants so they actually have a chance to survive - - - and NOT as an ARTIFICIAL WOMB with the ability to actually grow an infant from sperm-egg inception to birth.

    cheers . . .

    • Yup you beat me to it. This artificial womb will save millions of lives each year and prevent millions more from suffering disabilities caused by premature birth. Think of it as a replacement for the incubator rather than an artificial womb but with a much higher survival rate than the 30% we get with current incubators at 23-24 weeks.
      • This artificial womb will save millions of lives each year and prevent millions more from suffering disabilities caused by premature birth.

        Your numbers seemed high, so I looked it up [who.int].

        Preterm birth complications are the leading cause of death among children under 5 years of age, responsible for nearly 1 million deaths in 2015.

        Three-quarters of them could be saved with current, cost-effective interventions.

        So if current, cost-effective interventions were applied we'd have about a quarter-million lives lost that could potentially be helped by this new technology.

        Assuming it would be even more expensive than existing interventions, it would be available in an even smaller percentage of cases than those. But let's say it was equally available. That means ~62,500 lives saved.

        It's just a first step. It doesn't need to be a miracle to be worth doing.

    • This is a situation where slippery slope will NOT be a logical fallacy. As the technology progresses earlier and earlier premature babies that would otherwise die would be saved with this method. Eventually the lines between premies, fetus and embryo will become blurred.
    • THIS 'device' is being put forward as a means to extend the viability of really early premature birth infants so they actually have a chance to survive - - - and NOT as an ARTIFICIAL WOMB with the ability to actually grow an infant from sperm-egg inception to birth.

      True, but that doesn't mean it won't eventually become an artificial womb. If they're successful at using it to keep babies who are 15 weeks premature alive and healthy through their full development, then clearly the next step is to use it for babies who are 16 weeks premature, etc., etc. As they push back the age of viability new challenges will arise and be solved, and step by step it will get pushed back all the way to starting from an embryo. The development process will take years, maybe decades, but

    • wow! Thanks for all the kind remarks.

      Yes, I know this is /. and reading the article is not required to post in this arena.
      However, I still support my original point that this is NOT the headline-grabbing Artificial Womb.

      It IS a means of providing extended womb-like support for really early premature births, and should be lauded as a serious accomplishment in it's own merits, as it provides a MUCH better option than a premature birth installed in an oxygenated tank for 'hopeful' completion of the embryo's

  • Do sheep-people dream of electronic androids?

  • ... but I find this effing creepy.

  • PERFECT name for a nut job
  • With each global conflict splitting mankind along a more general difference, the gender is the ultimate discriminator to base a war on now that we will think we can do without the other gender...
  • I watched a friend struggle with a premature birth. The baby was born at 26 weeks, just barely past the point of viability. She's very lucky that her child is totally healthy, but it was a long struggle. This kind of technology could save a lot of suffering, and maybe even a lot of effort and expense. Her child needed constant monitoring and interventions to develop somewhat normally. It would have been terrific to be able to put him back into a plastic womb and finish developing that way.
  • Baby sheep born in artificial womb and humans might be next?

    Why would we use humans to give birth to baby sheep if we've already got an artificial womb to do that?

  • There are already too many people.

"All the people are so happy now, their heads are caving in. I'm glad they are a snowman with protective rubber skin" -- They Might Be Giants

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