Endocannabinoids Contribute To Runner's High 112
MTorrice writes: After a nice long bout of aerobic exercise, some people experience what's known as a "runner's high" — a feeling of euphoria coupled with reduced anxiety and a lessened ability to feel pain. For decades, scientists have associated this phenomenon with an increased level in the blood of beta-endorphins, which are opioid peptides thought to elevate mood. Now, German researchers have shown the brain's endocannabinoid system—the same one affected by marijuana's 9-tetrahydrocannabinol (THC)—may also play a role in producing runner's high, at least in mice.
So that's why! (Score:1)
I always have the munchies after a long run!
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Yeah accept these rats never would have even came into being without science. All lab rats are specially bred. They need control groups or just rats with certain genes or traits.
DEA declares running illegal (Score:5, Funny)
In a bid to short cut the supply lines of those "runners" getting high, the DEA has announced a maximum speed limit for unpowered human locomotion: 2mph. Those caught in pedestrian speed traps going over the 2mph speed limit will be jailed a minimum of 7 months.
Kingpins of cartels like the Running Room and gyms will face stiffer penalties due to their "intent to traffic" and could face up to 8 or more years in federal prison.
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Or a White House press release.
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In a bid to short cut the supply lines of those "runners" getting high, the DEA has announced a maximum speed limit for unpowered human locomotion: 2mph. Those caught in pedestrian speed traps going over the 2mph speed limit will be jailed a minimum of 7 months.
Kingpins of cartels like the Running Room and gyms will face stiffer penalties due to their "intent to traffic" and could face up to 8 or more years in federal prison.
If Hillary gets in, I wouldn't be shocked to see this headline in a real newspaper.
I've heard that she's really hitting the addiction theme hard on the campaign trail, but I just can't be arsed to go and look up her detailed platform points on these things. What's her position on actual drug laws, enforcement, decrim/legalization, etc?
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In a bid to short cut the supply lines of those "runners" getting high, the DEA has announced a maximum speed limit for unpowered human locomotion: 2mph. Those caught in pedestrian speed traps going over the 2mph speed limit will be jailed a minimum of 7 months.
Kingpins of cartels like the Running Room and gyms will face stiffer penalties due to their "intent to traffic" and could face up to 8 or more years in federal prison.
This should have been rated Insightful due to the fact it makes just as much sense as outlawing a fucking harmless plant.
Ironically, treadmills kill more people every year than cannabis ever has.
Re: DEA declares running illegal (Score:4, Insightful)
Cannabis don't have to be smoked, it can be eaten. Peoples with psychiatric problem are more prone to substance abuse. The 1950 have called and they want their debunked argument back.
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Cannabis don't have to be smoked, it can be eaten. Peoples with psychiatric problem are more prone to substance abuse. The 1950 have called and they want their debunked argument back.
As much as I would like it to be different, the GP's claim is not unreasonable.
From the npr.org [npr.org]:
'There have been nine studies following hundreds to thousands of people for decades looking for a connection between marijuana use and psychosis. All but one of these studies suggest that marijuana use is associated with schizophrenia. Sir Robin Murray, a psychiatrist at King's College in London, says that evidence changed his mind about weed. "Even I, 20 years ago, used to tell patients that cannabis is safe
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(admittedly, a bit further in the article, it is mentioned that the relation is not neccesarily causal -my bad)
Even if it is causal, IIRC it's currently understood to have the potential to trigger (or be one in a combination of triggers) for a psychotic break in people already susceptible to schizophrenia.
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(admittedly, a bit further in the article, it is mentioned that the relation is not neccesarily causal -my bad)
Even if it is causal, IIRC it's currently understood to have the potential to trigger (or be one in a combination of triggers) for a psychotic break in people already susceptible to schizophrenia.
You can argue the same for psychedelics like LSD, which are generally safe but can also cause disastrous psychotic breakdowns for some people.
The problem is that we don't know which people are susceptible to schizophrenia in advance.
So it's a bit like playing Russian Roulette, albeit there are a hundred empty chambers (or whatever) and one bullet.
The difference with a legal drug like alcohol is that while it undoubtedly causes long term health problems in many people, it rarely produces immediate psy
Re: DEA declares running illegal (Score:4, Informative)
Harmless? Marijuana is linked to higher chances of developing mental disorders and other psychiatric problems. Not to mention the smoke is harmful for our lungs.
I'll give you that alcohol and tobacco are far worse, but to call it harmless is just as wrong as to call it as dangerous as heroin.
CBD is a fantastic anti-psychotic and is going under further research. and anything can unlock a genetic predisposition ... alcohol, light... anything can trigger it.. not just cannabis
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I don't believe the only links to mental illness is that it can, in some cases, cause earlier onset of symptoms in those already predisposed to have schizophrenia.
And interestingly enough, so can a vegan diet.
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Re: DEA declares running illegal (Score:4, Informative)
http://blogs.psychcentral.com/... [psychcentral.com]
But where I first heard of th econnection was in a fascinating book written by Mark Vonnegut (son of Kurt) called "The Eden Express". In th elate 60's early 70's, he was living the good hippie life in Western Canada, and went schizophrenic, twice. He was eventually cured - dunno if that was the right word - but he's now a pretty well known pediatrician. But his issues largly stemmed from diet along with a predisposition to the issue. He noted that the cruel aspect of it was that it started by trying to be "good", and not cruel, so eating meat was a bad thing. So he got into a positive feedback loop
Here's an old article from People magazine 1975 : http://www.people.com/people/a... [people.com]
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I suspect a much more causative relationship.
I don't think it makes you go psychotic, but I think if you are predisposed, it can trigger a break.
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And a $10 million reward for bringing in Usain Bolt.
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And both feet must simultaneously be in contact with the ground during each stride when switching from one foot to the other. Otherwise, you also go directly to jail.
Re:Arrested for running (Score:4, Insightful)
All of them naturally, as they're already doing :).
Why would you run if you don't have anything to hide?
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Only if they happen to look Latino. Others will only be briefly detained.
Hmmm ... (Score:3, Interesting)
So if our brains are hardwired with receptors for this stuff, maybe it's time to actually look at it and evaluate it for what is is instead of this bullshit moralistic prohibition which is there to keep a bunch of religious assholes happy?
Maybe start by stopping treating marijuana as a narcotic, when in fact it's nothing of the sort?
The scientific facts have never matched the bullshit claims by the "just say no" crowd, so let's start making some actual evidence-based policy.
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So if our brains are hardwired with receptors for this stuff, maybe it's time to actually look at it and evaluate it for what is is instead of this bullshit moralistic prohibition which is there to keep a bunch of religious assholes happy?
Um, Puritanism is the State Religion in the USA. They offer platitudes about separation of Church and State, but all the evidence points in the other direction.
Puritanism is also considered Satanic by some serious theologists (assuming the premise).
Put that in your pipe a
Re:Hmmm ... (Score:5, Insightful)
Um, Puritanism is the State Religion in the USA. They offer platitudes about separation of Church and State, but all the evidence points in the other direction.
If drugs were illegal in the U.S. merely for puritanical reasons, why would they also be illegal in places like China, North Korea or Vietnam? The religion they all have in common is statism.
The reason for outlawing them is simple: You belong to the state, and if you're taking illegal drugs, you're not being a productive member of society. If you're selling illegal drugs, you're not contributing to the welfare of the state in the form of taxes. It all goes back to statism. Of course, most statists don't like to admit this.
Saying this as a pro-legalization Christian who also doesn't like puritanism/legalism/statism...
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Um, Puritanism is the State Religion in the USA. They offer platitudes about separation of Church and State, but all the evidence points in the other direction.
If drugs were illegal in the U.S. merely for puritanical reasons, why would they also be illegal in places like China, North Korea or Vietnam? The religion they all have in common is statism.
The reason for outlawing them is simple: You belong to the state, and if you're taking illegal drugs, you're not being a productive member of society. If you're selling illegal drugs, you're not contributing to the welfare of the state in the form of taxes. It all goes back to statism. Of course, most statists don't like to admit this.
Saying this as a pro-legalization Christian who also doesn't like puritanism/legalism/statism...
Marijuana is not illegal in North Korea. You can buy weed in the supermarket in most areas of North Korea. It is illegal in Pyongyang only, and the reason for that is primarily because it is seen as "a drug for the lower classes". They also don't want to become known as a marijuana haven. Given all their other reputation issues, they don't want the "Amsterdam" reputation also. Although the only thing they have to worry about is most likely that their weed is very weak.
Meth is also seen as an acceptabl
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Yup. Making LSD illegal sure penalized that black guy, Timothy Leary.
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The scientific fact is that most "recreational" drugs attach to certain receptors, which are meant for internal communication only. The euphoria you get from drugs is due to them being in far higher dosage than what the receptors normally expect.
This abuse leads to desensitisation, making it difficult for drug users to feel good naturally.
Besides, the argument that the brains are hardwired is kind of stupid. Your stomach is hardwired to be filled with hydrochloric acid, but that doesn't mean you should drin
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More like due to a possible psychosis. Nobody wants a hallucinogen crazed person starting a shooting spree because that person sees demons around.
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Even LSD was designed. Also, are you asserting the drug would not have otherwise been made? That's silly and illogical to conclude. I say this as a drug user.
Legalize, tax, spend the saved money on rehabilitation and education. If we couldn't already get drugs we'd not have a drug problem. Legalization isn't going to make people run out and try shooting up heroin. Those who want to already can and that's why we have a "drug problem."
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Not by any definition of 'designed' I'm aware of. Wikipedia says it best:
"LSD was first synthesized on November 16, 1938 by Swiss chemist Albert Hofmann at the Sandoz Laboratories in Basel, Switzerland as part of a large research program searching for medically useful ergot alkaloid derivatives. LSD's psychedelic properties were discovered 5 years later when Hofmann himself accidentally ingested an unknown quantity of the chemical."
In other words, it's most noted property was not
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They designed the drug to match an already existent behavior much like the designer drugs are created to match (or mimic) existing drugs. I'm not sure how you'd think that's not designed?
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Not by any definition of 'designed' I'm aware of. Wikipedia says it best:
"LSD was first synthesized on November 16, 1938 by Swiss chemist Albert Hofmann at the Sandoz Laboratories in Basel, Switzerland as part of a large research program searching for medically useful ergot alkaloid derivatives. LSD's psychedelic properties were discovered 5 years later when Hofmann himself accidentally ingested an unknown quantity of the chemical."
In other words, it's most noted property was not known at the time it was first synthesized. Not sure how that could be called 'designed'.
Ergot alkaloids were known to produce hallucinations (amongst other less pleasant effects) since the Middle Ages, at least.
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Source please. If they were looking specifically for psychedelics, why did take 5 years to figure out it had that property in spades and then only by accident?
Ergotamine had been known as a vasoconstrictor and was used to treat migraines. I've never read a single source about Hofmann's work that indicated he was looking for psychedelics specifically.
Wait...never mind, the answer is right on the Albert Hofmann Wikipedia page: [wikipedia.org] (Gotta love WP...)
"While researching lysergic acid derivatives, Hofmann fi
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I get what you mean now and it may be my mistake. Designed means, to me, designed for a purpose (albeit maybe several purposes might become evident) where as the rest would be those remaining in nature or extracted from nature such as those which use opium as their base. I imagine that it is I who has the definition wrong. If so then, my bad. I still don't know why you'd assume the drug wouldn't have been made, we're creative and curious creatures. It may well have still been created even if LSD were availa
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Nope, wasn't arguing that at all. My only point was that LSD was to my knowledge, and have now confirmed, a pretty serendipitous discovery.
But to rant on a bit...in my opinion, most drugs are not really 'designed', and I've always bristled at the term 'designer drugs'. Ask people to name as many 'designer drugs' as they can and I'll bet you 99.99% of the answers will be some form of MDMA (discovered 1912), ketamine (1962), or maybe GHB (1874). There are a handful of drugs out there on the fringe of the
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See, I'd call anything designed to do something as being a designer drug vs. something that was discovered. I'm not sure if that makes any sense or not. But, you know, designed - that's the way I always thought of it. I can't say that I've ever heard anyone actually define it.
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2012 wants its propaganda back, too.
Again from Wikipedia: [wikipedia.org]
"While police sources speculated that the use of a street drug like "bath salts" might have been a factor, experts have expressed doubt toward this speculation as toxicology reports were only able to identify marijuana in his system, leaving the ultimate cause of Eugene's behavior to remain unknown."
Hysterical anti-drug propaganda: scaring Americans stupid since 1914. [nytimes.com]
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Maybe you should stop smoking shitty weed or smoke weed before you elect to comment.
https://en.wikipedia.org/wiki/... [wikipedia.org]
I'll quote the important part:
"In large enough doses, THC can induce auditory and visual hallucinations."
Sit down and shut up while the adults talk. Just because you've never enjoyed anything other then brick weed doesn't mean you understand anything. Some of us have been smoking this stuff for longer than you've been alive.
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Your stomach is hardwired to be filled with hydrochloric acid, but that doesn't mean you should drink it.
Oh, bollocks...
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Mice (Score:5, Funny)
Mice get runner's high? No wonder they love those little wheels...
"What's the matter with your eyes, boy?" (Score:4, Funny)
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Sorry Sir, you should have a designated driver when you go to the Gym.
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Although your comment made me laugh, sometimes it's not that far from the truth. Trying to drive a car after an hour plus run can be a little dangerous sometimes. You can be all sorts of buzzy and distracted for well over an hour after it. From dehydration to exhaustion, there are all sorts of reasons driving can be a bad idea.
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One time after finishing a strenuous 16 mile hike in the mountains I got back to my car and was driving back on the highway. I was going under the speed limit but not below 45. I was just kind of in a daze and readjusting to city lights. A cop pulled me over thinking that I must be drunk or something because I wasn't driving the speed limit. I told him what was what. Realizing that I wasn't drunk, he let me go and told me to drive carefully.
Just because you weren't drunk doesn't mean you weren't driving dangerously.
The argument from environmentalism... (Score:4, Funny)
So, if you go for (say) an hour's hard run, you're burning many hundreds of extra calories. That translates into "burning" (converting to carbon dioxide and water) a hundred or more grams of carbohydrate and protein, and/or tens of grams of fats. Worse, you need to replenish that energy with food-grade material, which most often has been farmed, trucked, and packaged, all of which consumes more energy. That one-hour run ends up cranking out hundreds of grams of carbon dioxide.
If, on the other hand, you simply burn through one medium-sized joint, you're only combusting a few grams of plant material. I'll bet the total CO2 output is less than ten grams.
Admittedly, there are health benefits to running. But at what cost to the health of the planet?
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"one medium-sized joint, you're only combusting a few grams of plant material"
but about 30 minutes later you'll still eat food-grade material that most often has been farmed, trucked, and packaged ;-)
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I expected your comment to be modded funny. Smoke a joint to save the environment. I consider myself environmentally conscious, but (if you weren't actually trying to get a laugh) that argument is ridiculous. I'm sure nobody runs just for the high. They run for their health. Telling people they shouldn't run because it's bad for the environment is wack. Probably modded up by obese people because it justifies not exercising.
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There's a "semi-recognized" affliction where people are addicted to exercising - they are not so much doing to become/stay healthy, they are doing it become they are compelled to do so, even to a point of it having a negative impact on health, family/relations, work etc.
(I use "semi-recognized" since it seems to differ quite a bit from country to country)
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So, if you go for (say) an hour's hard run, you're burning many hundreds of extra calories.
Umm... only if your name is Barry Allen or Eobard Thawne..
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Technically, you're both morons. Trained individual typically burn 10-15 kCals/minute while running, so an hour of running for them is typically burning 600 - 900 kCals.
And yes, I have both the science and data to prove it.
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You must be high dude. No environmentalist would make that argument. Its a fake argument.
the weed dealer drives around town burning gas to get the weed to you. the grower uses tonnes of electricity because he has to work indoors. the lighter has butane in it. the papers were harvested from virgin forests... and other stupid arguments. You cant extrapolate down so much, your just making fun of the environmental movement.
If you were a runner you would know that it makes you a better walker, you are then able
Re: The argument from environmentalism... (Score:1)
You are an idiot. It was a fucking joke.
Christ sakes you people have no sense of humor. Maybe you need pot.
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No, it was a running gag.
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No man, that's what The Big Bambu was for!
https://en.wikipedia.org/wiki/Big_Bambu
Only Cheech and Chong's medium sized joints are "a few grams....."
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"Insightful"? Okay, I'll admit I was kind of nervous that that might happen.
No, I haven't seen a joint in a long time, so I'm not sure what one actually weighs. I figured it would be more than a gram, counting paper (which is also plant material that gets burned).
Yes, I was referring to ignorant-American "Calories" (kcal), not one-water-gram-degree-C calories.
No, I wasn't serious.
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So, if you go for (say) an hour's hard run, you're burning many hundreds of extra calories. That translates into "burning" (converting to carbon dioxide and water) a hundred or more grams of carbohydrate and protein, and/or tens of grams of fats. Worse, you need to replenish that energy with food-grade material, which most often has been farmed, trucked, and packaged, all of which consumes more energy. That one-hour run ends up cranking out hundreds of grams of carbon dioxide.
If, on the other hand, you simply burn through one medium-sized joint, you're only combusting a few grams of plant material. I'll bet the total CO2 output is less than ten grams.
Admittedly, there are health benefits to running. But at what cost to the health of the planet?
This is the sort of argument which sounds totally logical when you're high.
Comment removed (Score:3, Insightful)
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Don't say that.
I finished the C25K and wanted to start B210K, but then I took an arrow in the knee.
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then I took an arrow in the knee.
Wow. I think there's some confusion here about the meaning of "high."
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Nah, I meant that I had to quit running after an unrelated injury. I miss running a lot, though.
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And I have the bumper sticker [etsystatic.com] to prove it.
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I ran track in high school and have done C25k a few times (week 7 is where I stop). Your point still stands, though. If I was going to get a runner's high, i'd have gotten one by now. As it is, my "high" is kinda like the Lament Configuration: I'm just so happy when I stop running because I've stopped running.
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13 marathons in 5 years, 2 of which were 50 milers, 3 sub 3:00 hours, 5 bostons, 7 bqs, so some running experience...
but thru it all, still a slashdot reader and a nerd....
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13 marathons in 5 years, 2 of which were 50 milers, 3 sub 3:00 hours, 5 bostons, 7 bqs, so some running experience...
but thru it all, still a slashdot reader and a nerd....
Here: 13 marathons in 14 years, most just under 4:00 hours.
anjrober, it seems our running cred and our Slashdot IDs are aligned.
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I used to jog a lot. I NEVER got a runners high. There was no second wind either. Every minute was difficult, and it got more difficult with every passing minute, and the only way to keep going was either to become numb (ie, like those who stumble over the finish line in a daze) or just keep repeating "one more step" over and over. The only high was when it was over you were elated that you could stop.
But I do think some people get this high. But being humans, they are prone to assuming that everyone
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I used to jog a lot. I NEVER got a runners high.
Once you get the hang of it "jogging" can take little more effort than walking, so you're not going to have the same reaction. I can slowly jog or walk for a couple of hours and just feel pleasantly tired afterwards. I'm not knocking it, it's still good for you, and possibly better in the long term as there's less stress on joints (pun intended).
No wonder they are lethargic (Score:2)
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Marijuana makes you feel as though you had just completed a marathon.
Marijuana causes you to hurt everywhere and be unable to walk?
It is a cellular peptide cake (Score:3)
With mint frosting.
Ban school sports! NOW! (Score:2)
We can't subject our kids to something that is akin to smoking pot! On school premises to boot!
And they want to make it mandatory! Obama wants to make our kids addicts!
Thinkofthechildren! Ban sports!
Get rich off of this (Score:1)