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Newfound Bacteria Expand Tree of Life 30

An anonymous reader writes: It used to be that to find new forms of life, all you had to do was take a walk in the woods. Now it's not so simple. The most conspicuous organisms have long since been cataloged and fixed on the tree of life, and the ones that remain undiscovered don't give themselves up easily. You could spend all day by the same watering hole with the best scientific instruments and come up with nothing. Maybe it's not surprising, then, that when discoveries do occur, they sometimes come in torrents. Find a different way of looking, and novel forms of life appear everywhere. A team of microbiologists based at the University of California, Berkeley, recently figured out one such new way of detecting life. At a stroke, their work expanded the number of known types — or phyla — of bacteria by nearly 50 percent, a dramatic change that indicates just how many forms of life on earth have escaped our notice so far.
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Newfound Bacteria Expand Tree of Life

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  • >> You could spend all day by the same watering hole with the best scientific instruments and come up with nothing

    According to TFA, they DID spend all day by the same watering hole and ended up using the best scientific instruments (really fine filters) to make their discoveries.

    >> It used to be that to find new forms of life, all you had to do was take a walk in the woods. Now it's not so simple.

    And...if I'm following the TFA, this would still probably yield even more discoveries if a researcher used the same technique.

  • "It used to be that to find new forms of life, all you had to do was take a walk in the woods."

    True if looking for leprechauns; but not mermaids.

    I still haven't found the leprechaun, let alone caught him. But I did find a box of lucky charms once.
  • Contentious (Score:4, Informative)

    by jandersen ( 462034 ) on Wednesday July 29, 2015 @09:11AM (#50204099)

    Having only just skimmed the article, I may have missed some imprtant points, but it seems they are basing this discovery on DNA analysis, which all well and good as far as it goes. What is no doubt valid is that this method yields a classification, but what is less certain - or perhaps highly uncertain - is whether this classification reflects the evolutionary phylogeny of the organisms in the study.

    The big problem here is that DNA similarities probably only really match descendancy (or evolutionary relationship) well, when we talk about eukaryotes; this is because eukaryotes have sex: they go through cycles of meiosis/mitosis and all that, in which they recombine their genes in very rigorous way which ensures that DNA is inherited from predecessors. Prokaryotes don't have sex - instead they have different forms of lateral gene transfer, in which genes are acquired from many, seemingly unrelated organisms. The result of this is that the gene pool WITHIN what we perceive as 'a single species' of bacteria, like Eschericia coli, can be wildly different. Presumably there are genes within a single strain, that are fairly constant, and might be used to trace progeny, but I don't think anybody knows which they are yet.

    • Re:Contentious (Score:5, Informative)

      by Anonymous Coward on Wednesday July 29, 2015 @09:37AM (#50204329)

      Molecular ecologist/Microbiologist here

      Actually, evolutionary relationships by DNA similarity as you said work extremely well within all 3 domains of life. Typically we use a highly conserved gene to establish phylogeny- the most common being the small subunit ribosomal RNA gene (16S for Bacteria/Archaea, and 18S for Eukaryotes). This gene is conserved across all domains of life, and essential for the functioning of the ribosome (The little machine that makes proteins). Without it, the ribosome wouldn't form, and you wouldn't be living. Now, to the point of lateral transfer of genes- much of the genetic lineage of a bacterium is from vertical inheritance after replication of a cell- the cell divides, and is most closely related to the parent cell from which it originated. You get genetic drift as errors crop up in the genomes of bacteria, and these errors are propagated from cell to dividing cell. Eventually these errors either become a new functional gene, a silent mutation, or are enough to kill the cell. Alternatively (As you stated) you get new function via horizontal gene transfer. But essential genes (such as the gene that codes for 16S rRNA) are not transferred horizontally, and can be used to establish a meaningful phylogeny of life.

      Now the definition of a species within microbial life is somewhat contentious, and is typically established at a cutoff of 97 percent sequence similarity of the 16S/18S rRNA gene that correlates with a number of chemotaxonomic (functional/structural) changes. Otherwise yes, what differentiates an E. coli from E. albertii can be somewhat arbitrary. But using 16S/18S we can make much more meaningful and broad statements about higher taxonomic levels (Genus, Order, etc.). Binning genomes as Dr. Banfield did, and finding conserved marker genes like 16S in these novel genomes to establish phylogeny also allows us to infer functional traits and give at least some insight into what these uncultured microbes are doing.

      • Good to hear from somebody in a position to know, which I am not, unfortunately. Still, I got my impression from a discussion in a book written by professor Nick Lane: "The Vital Question"; maybe I didn't understand his words. Have you read his book?

  • This sounds really big and interesting. I hope there is an Ask Slashdot with Dr. Banfield.

  • Yowie and Bigfoot, you're up next!

    And when they do find Bigfoot, I'm hoping the Bears draft him as a defensive tackle, because he'd make an awesome 3-technique. Assuming he can pass the drug test.

    • Correct, genetic testing has been used to discredit all alleged Bigfoot samples brave enough to be tested. They have all turned out to be other known mammals.
  • by peter303 ( 12292 ) on Wednesday July 29, 2015 @10:05AM (#50204581)
    He combined his love of sailing with ocean microbe sampling to investigate the diversity of life. https://en.wikipedia.org/wiki/... [wikipedia.org]
    Incidentally Craig perfected the shotgun decodign technique which accelerated decoding the first human genome in the late 1990s (his of course :-). Now gene sampling is fairly routine way of mapping biomes all over the ecosphere.
  • So I have to ask: Did they happen to find the specific bacteria responsible for the common cold yet? (It seems to me that finding it might very well lead directly to curing it, after all...)

    • >> bacteria responsible for the common cold

      Dear Dice employee: your attempt to monetize SlashDot has failed and the site is for sale. You no longer have to tryhard-interact with the geeks you are attempting to "monetize" on this site. Please return to "Yahoo Answers" or the like whenever you feel like writing comments like this here. Sincerely, [EveryoneWithAnIDUnder600K]

      • Dafuq?

        (And if you're referring to the common cold being caused by a virus, then you clearly missed the joke.)

    • There isn't one specific bacteria that causes the common cold. As Sique said, it's usually a whole bunch of different types of viruses that could be responsible, usually rhinoviruses or adenoviruses, but there are others. The "common cold" symptoms are pretty much just low-level inflammation in the respiratory tract and some general inflammation.
      • Two-for-two. Clearly, my form of humor is much too dry for Slashdot.

        • Ah, fair enough. It's hard to tell when people are going for dry humor via text, especially when you've never interacted with them before (and how little some people know about biology).
  • by mbone ( 558574 ) on Wednesday July 29, 2015 @01:19PM (#50207489)

    The most conspicuous organisms have long since been cataloged and fixed on the tree of life, and the ones that remain undiscovered don't give themselves up easily.

    Certainly not true if by "conspicuous" they mean "ones you can easily see with the naked eye." Most insect and beetle species are not cataloged yet, and for smaller critters the situation is even worse. Heck, you might even find a new frog species in Manhattan [discovery.com].

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