The Cure Culture: Our Obsession With Cures That Are 'Just Around the Corner' 204
citadrianne writes: Cures for major disease always seem just a few short years away. We constantly read about promising new treatments for cancer, diabetes, HIV, ALS, and more. While the prognosis for these diseases has improved over the years — sometimes greatly — we still focus doggedly on the cure. "The idea of a cure is simpler, it's more appealing as a fantasy." This article takes a look at so-called "Cure Culture" — the focus on reaching for a cure when our scientific efforts may be better expended attacking a disease in other ways. It asks, "Why are we telling our children, our friends, and our family members that we are going to cure them? ... What does it mean to be cured of a disease that is encoded within your DNA from the moment you become a zygote until the moment you are dead? ... And why are we eschewing or overlooking treatments—real, honest-to-god treatments—that can let patients lead longer, more normal lives?
Customers vs Patients (Score:5, Insightful)
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If Company A develops a treatment and Company B develops a cure, which company would get your money in case you happen to get the disease in question?
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If Company A develops a treatment and Company B develops a cure, which company would get your money in case you happen to get the disease in question?
Note that this is exactly what has happened with the new generation of anti Hepatitis-C medications, with complete and permanent cures of a chronic viral infection at rates of 95+%. In about 12 weeks.
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Company A has cash flow. A should purchase B in order to shelve the cure. That's just smart business.
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Re: Customers vs Patients (Score:2)
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If Company B cures the disease, then Company B gets paid until nobody has the disease then Company B has to invent a new cure or go out of business.
At that point company B has made more money than all of the treatment manufacturers were making combined. It set a high price for its cure, everyone bought the cure. If the disease was Diabetes, they grossed 2 trillion dollars, easy. At that point B could just buy Google or a medium size country if they still felt like they needed something to do.
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Isn't the problem the exact opposite? That we struggle to find cures when treatments are so much more profitable? That medicine is viewed as a profit generator rather than an utterly essential aspect of a modern society? This article reads like it was written by a spokesperson, and turns a blind eye to every disease that once had no cure - but now does.
I'm cynical about the health care industry too but you're missing the key variable here.
We can essentially cure two classes of illness, infection and physical defects.
With infection we can kill the parasite and you're cured, and with physical defects we can do surgery and you're cured, but otherwise we're kinda helpless.
Cystic fibrosis is a problem in the patient's genome, we can't cure them unless we fix the genome. Type 1 diabetes is the body either not producing insulin, we can't cure that without gettin
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That's *a* problem certainly, but it's not *the* (not that there's any singular problem in the first place), and it's a problem that's tied to Big Pharma. But the article isn't about Big Pharma. It's about Big Charity, which has a separate set of problems.
Isn't the article actually about... (Score:2)
That's *a* problem certainly, but it's not *the* (not that there's any singular problem in the first place), and it's a problem that's tied to Big Pharma. But the article isn't about Big Pharma. It's about Big Charity, which has a separate set of problems.
Isn't the article actually about... "You big charities concentrating on finding a cure when there are treatments for CF are really annoying the piss out of those of us who are currently making an ass-ton of money off of selling treatments".
So the *actual* problem they are addressing is the problem that big charity isn't funding their treatment research, and they are instead having to fund treatment research themselves, and that cuts into their profits. In other words, it's not enough that all of the public
Re:Customers vs Patients (Score:4, Insightful)
This comes up all of the time. Here is a thought - you have a number of countries - like the entire rest of the world - where 'profit' isn't the driving force for medical care. There are dozens of governments who would love to have inexpensive cures. And these countries have lots of smart people, have lots of high end research facilities, have had lots of time. If there was some sort of simple 'cure' for any one of a number of chronic, expensive diseases it would have been studied six ways from Sunday.
It's not some evil collusion of rich, nasty old men. It's just that biology is fucking hard.
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Drug A, a cure. Drug B, treatment Time til profit: Since it offers benefits far above a treatment, the cure gets gets a breakthrough therapy designation and accelerated approval from the FDA review panel, leading it to be approved months or years earlier than the treatment. Once in the market, the
"cure for cancer" (Score:5, Informative)
Cancer is so diverse, saying we have cure for cancer is like saying we have cure for viral infections.
I'm pretty sure lots of cancer types are now curable, and the number is growing.
Re:"cure for cancer" (Score:5, Funny)
Obligatory SMBC: http://www.smbc-comics.com/?id... [smbc-comics.com]
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even ones that do vary a lot from one cancer to another
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I think you're conflating "tailoring treatments based on known DNA markers,antigens, and drugs" with "identifying new markers from tumor cell biopsies and creating new treatments based on those markers." We can do both, but tailoring is the faster of the two. Your statement is a gross oversimplification and overstatement of what current technology can do for cancer treatment (to say nothing of what's available to the general public vs what we can do in a lab or a test tube).
You make it sound as if a new
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Uhhhhhh. Carl June has been working on treatments for all types of cancer in which he genetically modifies T-Cells by reading a genetic marker out of a biopted cancer cell, installing a new antigen into a T-cell's DNA code, and releasing it back into the patient.
Essentially, the cancer cells produce certain proteins differently: the protein on your cell surface for transporting a certain ion or signalling certain RNA messages may be structured in thousands of different variations and still carry out its
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Very true. We have cures for many types of cancers if found early enough. For other types of cancers (eg pancreatic) the issue is being able to find it before it causes symptoms, which usually means it's too late.
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For other types of cancers (eg pancreatic) the issue is being able to find it before it causes symptoms, which usually means it's too late.
Well, we could likely detect most of these cancers, if we just do an high res full body MRI scan of everyone every 6 month. But that would not only be very expensive but would likely generate a lot of completely unnecessary surgeries as many things that get detected there would either be completely harmless or get killed by the immune system before they could cause any problems. We do not only need something that can detect cancer, we also need something that will not generate a lot of false positives and i
Actually, islet cell adenocarcinoma is detectable. (Score:2)
Actually, islet cell adenocarcinoma is detectable. You can do it with a rather simple/cheap blood test.
However, nearly no insurance carrier will pay for this blood test (I just had a friend who died from islet cell adenocarcinoma (pancreatic cancer), which was in fact treatable, but Kaiser Permanente did not cover the testing at the point she had her first symptoms.
NB: The following is NOT medical advice; consult an oncologist, if you have any of the following situations...
It was a type that would have bee
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Naked mole rats seem to have the right idea when it comes to cancer (or the various diverse forms of cancers if you prefer). They have an extra genetic component against cells reproducing when they're too tightly packed, as would happen in cancer.
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I know the point you are trying to make, and yes indeed cancer is a huge family of diseases, but all cancers do share a number of things in common: uncontrolled cell growth, lack of programmed cell death, etc., and advancements in fighting these common attributes have led to many of the "cures" you refer to. It's also why some cancer drugs work for many, many types of cancers, becaus
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I'm not obsessed! (Score:5, Funny)
I haven't been obsessed with The Cure since the 90's when grunge took over.
You sure you're not just... (Score:2)
...in the closet about all that?
Do you often find yourself playing with finger puppets which resemble people around you?
Optimism, and profits ... (Score:5, Insightful)
Part of this is the need for people to believe there is hope, and therefore want to believe desperately that some magic bullet will come along.
But, I fear the biggest problem is the corporatization of the surrounding charities.
Things like the Pink Ribbon stuff is increasingly about for-profit marketing [bcaction.org], and less about actually generating money for research.
So, people put lots of hype into marketing the future cure because it can be fairly lucrative. Cancer "charities" can be a big business these days, because they capitalize on fear and hope.
And much of what happens is more about PR and profits than any actual medicine.
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And you can only sell a cure once. Treatments are repeat business.
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Re:Optimism, and profits ... (Score:4, Insightful)
Worse than that (which is already pretty bad) is by the time they take out management expenses (remember, some of this is essentially for profit) a very small amount of donated money even goes to that.
Many of these campaigns seem to be more about getting goodwill with being seen to care about cancer, but not actually focused on doing anything. And then all that happens in the for-profit or for PR places are competing for donations which could actually be doing something.
I've seen a lot of stories where huge sums of money go to various breast cancer campaigns, but that it's mostly about selling shirts and connecting your brand with caring, even if you do nothing concrete.
It just seems like the whole "awareness" campaign has become a cynical industry which does nothing at all for the people it purports to be helping.
Obsession ... or Optimism? (Score:2)
Early Detection Trumps Everything. (Score:4, Insightful)
Earliest detection can lead to stopping a problem or getting rid of it with minor treatment or life style changes, so health systems are promoting "wellness" programs involving early detection/monitoring.
If we manage early detection on a large % of the population, we won't need as much "treatment" and "cures."
That would decrease the cost & need for healthcare overall and lead to a healthier population. A lot of companies are working on aspects of this.
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Early detection of tumors can increase mortality (because not all tumors are malignant, but all cancer treatments to date are nasty nasty nasty).
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Note: screening is not especially harmful, what is harmful is panicking and receiving nasty nasty treatment that was entirely unnecessary. Also be warned that many doctors are innumerate (and other doctors are afraid you'll sue them). If you screen for cancer more often or outside the recommended age ranges, be damn sure you calculate the odds it's a false positive and that you understand both the risks of receiving unnecessary treatment and the risks of postponing treatment. If you can't do this, you shoul
Are you on the wrong planet? (Score:4, Insightful)
Treating symptoms should only ever be a short term comfort solution while Medical Science looks for a cure. It should ALWAYS be all about the cure. Article is exactly wrong.
We don't know everything yet. Deal with it. (Score:5, Insightful)
Medicine is all about treating the symptoms, hiding the symptoms, masking the symptoms, naming the disease after the symptoms.
Hogwash. That is only true when we do not understand the underlying condition. There are plenty of conditions we understand quite well and can treat the underlying cause. For those that we don't yet understand we comfort the patient as best we can until we can figure out what causes the disease. Finding out may take longer than the life of the patient sometimes.
The doctors don't know what is wrong with you.
Sometimes they do and sometimes they do not. We know a lot about a lot of diseases but we do not know everything about every disease. If you think doctors never know what is wrong with you then you don't really understand what you are talking about.
They tell you you have "Red spots on arms and upset stomach" disease, but that is not a disease, those are just symptoms, and they won't cure you of the disease because they don't know what is wrong with you. Instead, they will put you on medicine, that will hide those symptoms...until you stop taking your medicine, and then the symptoms are right back again.
That only happens when the underlying cause is unknown. Sometimes treating the symptoms is the best we can do. Frequently we can do much better. My wife happens to be a pathologist specializing in skin. She sees "red spots on arms" all the time. Sometimes the cause is known with 100% certainty. Sometimes the best she can do is to give a differential diagnosis.
My grandmother was having seizures, so they put her on anti-seizure medication. Do they know what was causing the seizures? No.
Ahh, so because doctors don't know about the root cause of that specific condition for that specific patient, you generalize that to say that they know nothing in general? That simply isn't true or fair.
Do they care? No.
If you think the doctors don't care then you don't actually know any. They care very much. It's why most of them went into the profession. They don't know how to cure everything but that doesn't mean they don't care.
Treating symptoms should only ever be a short term comfort solution while Medical Science looks for a cure.
Which is the point you seem to be missing. Sometimes finding a cure takes a long time. The human body is absurdly complicated and disease pathology even more so and there is a lot we still don't know. A cure may take several lifetimes to find. That doesn't mean we understand nothing and it doesn't mean nobody cares.
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I don't know what fucking shitty doctor you go to, but mine actually tries to do their damned job. Maybe you should get a new doctor.
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It's Sturgeons Law. 90% of anything is crap.
The first doctor I saw for my current condition didn't even realize I was at death's door despite the fact that an MD that is a family friend saw it right away. He was content to be my suburban drug pusher and didn't do any sort of competent physical exam of me.
If I hadn't gone there specifically to get my blood checked, I would now be DEAD. That's how bad my condition was.
The blood test made it obvious even to Ferret Face.
Then I went to the family friend...
You need to see a different doctor (Score:2)
Did you know doctors don't do diagnosis any more?
That will come as a shock to my wife who actually is a doctor and provides diagnosis all day long.
Seriously my friend, you have NO idea what you are talking about if you truly believe that.
Remember the TV shows about doctors when they would try to figure out what kind of disease you had, possibly opening up one of those medical books on the shelf behind their desk? Yeah, they don't do that any more.
Once again you are completely, 100% wrong about this. I will be happy to introduce you to as many physicians as you can stand to meet (I know a LOT of them) who will be happy to show you what they actually do when they are stumped. They absolutely do crack open the text books on a routine basis. Furthermore, real doctor
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Yes, you are going to die. However, if you send me enough money, I'll send you a magic rock that will keep you from dying of hypochondria.
Don't use steroids for fungal infections (Score:2)
Sometimes the cause is known 100%. For the rest of the time, there's prednisone.
You don't want to use prednisone (or any other steroid) if you have a fungal infection. It can actually suppress the immune system and make the fungal infection worse while having no beneficial effect on the problem.
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Medicine is all about treating the symptoms...
At the onset of serious illness often the answer to that is "yes". And that's a good thing. Because the "symptoms" can kill you. A common fever from an infection can kill you, even in cases where the actual infection can be cleared by the body itself is short order. The same with anaphylaxis. The allergic reaction as such won't kill you, it's the lack of breath from your throat swelling shut, or precipitous drop in blood pressure, (with heart failure) that kills you. Treating those symptoms is 99% of "curin
No one wants treatment (Score:5, Informative)
I am on treatment. Have been for years. Treatment fucking SUCKS. It takes over your life. Treatment controls what you eat, drink, what medication you take.Treatment keeps you alive and stable, but it is not the same as a cure. It's what we beg for until we get a cure.
Treatment means I get twice as tired as a normal person my age.
Treatment means I can't stay up late, get drunk, or smoke marijuana.
Treatment means keeping your blood pressure low that you need Viagrea to get an erection when you are 30.
I thank god for treatment - it keeps me alive. But it is not enough.
GIVE ME THE CURE. Some people will literally kill for a cure. If you tell someone they can cure the lung cancer their 8 year old child has just by killing a criminal in China and stealing their organs, some people will do it.
Treatment is nice - but it isn't close to a cure.
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I sympathize, but there is no cure for damaged kidneys. The damage can't be repaired and must be replaced. Until we can find a way to regenerate organs or create better artificial ones, your best shot is a kidney donor -- and I urge you to find a way to ask for a donor. A friend of mine donated his kidney to a young guy he didn't even know well -- a friend's daughter's husband, I think. He figured he was in his late 40s and could do fine with just one kidney while it would make a world of difference
Not just cures, but inventions too. (Score:5, Interesting)
Story: New energy source based on [insert some form of unicorn fart here] may one day solve energy crisis!
Story: New memory storage based on [insert excited hand waving] may one day replace current RAM!
Story: New computing method based on [something, something, carbon, something] may one day re-instate Moore's law!
Story: New AI algorithm based on [GAs, deep multi-layer neural nets, connecting organic brains together, a little man in a box that answers the questions and pretends to be a machine] may one day give us true artificial intelligence (whatever the fuck that means).
At 57, I've been hearing this crap since I was 6. There's no magic energy source. Moore's law has been stopped by physics. HAL has yet to enter the building. There's no cure for cancer or alzheimers, and so on.
Editors and writers with liberal arts or journalism degrees who can't evaluate the research anyway *love* this kind of filler shit because it attracts the eyeballs of the sort that read popular science magazine and take it seriously. It's the science literature equivalent of Reece's Pieces (meaning no disrespect for that fine candy).
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At 57, I've been hearing this crap since I was 6.
hey you forgot to mention we will be on Mars 20 years from now and we will have fusion power plants in 10 years (been said for past 50 years). And we're 15% into the 21st century, where's the flying cars? oh wait we have a few of those roadable airplanes.
But SCIENCE am I rite? (Score:3, Interesting)
Begging the question? (Score:3)
Does anyone else get the feeling that the author has decided we're all obsessed with cures just so they could write their article bemoaning the fact?
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I found the first statement in the summary disturbing:
While the prognosis for these diseases has improved over the years — sometimes greatly — we still focus doggedly on the cure.
Homosexuals are intentionally contracting HIV so they can stop worrying about HIV. This was a big thing in the 90s, right down to people getting on TV to tell folks that HIV wasn't really a problem now because it's "a Managed Condition instead of a Disease". Do you know how horrifying that is? Contemplate that. Anyone you know may, in fact, think that the fucking plague is a managed condition. They might think, hey, so I got this skin condition t
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What, like this movie?
The Returned: http://www.imdb.com/title/tt20... [imdb.com]
Zombies that are completely normal people unless they don't take their retroviral injections!!!
Zombie babysitters are just fine until they forget their meds and eat the baby! ;)
A Good Point (Score:2)
I think the writer makes a good point. How do you "cure" something that is part of your DNA? To put it in perspective, how do you "cure" yourself from having brown eyes? I think the best you can hope for is to "treat" your brown eyes with differently colored contacts.
As a person with a chronic, degenerative, genetic disease (type 1 diabetes), I have become less interested in talk about cures, and more interested in improved treatment. Specifically, an inexpensive, non-invasive method of detecting glucos
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Gene therapy for psoriasis? Really. While I can sympathize as someone that might get a nasty case of skin GVHD, it's just not in the same ballpark as other conditions where bleeding edge medical experimentation is actually considered acceptable.
You're just going to have to accept the fact that children with cancer are way ahead of you on that train and that's just in it's early stages yet.
It's the circle of life..... (Score:2)
Why would you run a story that says "Treatment of cancer type "A" has been marginally improved and an additional
Why did I call this the circle of life? Because the media jumped on the initial sickness for great sensational headlines. Then they
nature has a cure (Score:4, Interesting)
This is a hard reality for humans to accept, but there is a permanent cure for many terrible diseases.
We call it DEATH.
Am I joking? No.
We have all seen those dramatic nature shows where the lion catches the gazelle and rips it apart. The narrator of the show explains that by catching and eliminating the slower gazelle, the lion benefits the gazelle species by removing defective elements that otherwise would reproduce.
Human evolution has taken a turn for the worse. Rather than eliminating the weak elements and promoting the strong, we have reversed the evolutionary direction. We expend great resources to help the weak survive. OTOH, If a certain deadly disease was allowed to run its course, and all victims died before they could reproduce, the disease would kill itself. It would be removed from the gene pool.
If we live long enough as a species, and don't blow up the planet, we may well solve these problems without too much death and discomfort. Nature's way is not pretty to watch.
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Natue hasn't a clue. (Score:2)
Human evolution has taken a turn for the worse. Rather than eliminating the weak elements and promoting the strong, we have reversed the evolutionary direction.
In your world Stephen Hawking dies in 1964 before completing his graduate thesis.
How does eugenics define "strength and weakness" in a modern society which is fundamentally defined by intelligent --- cooperative --- behavior? Brains, not brawn
We spent a weekend in November hunting deer for sport with superbly engineered guns and bows and haul the carcasses out with our FWD and ATVs.
When we want meat on the table, we raise chickens and cattle on an industrial scale.
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Interesting... More variation -> more possible answers to some future species crisis down the road.
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If you don't feel at least a little guilty about meds over a million dollars and a blood debt of 20 or 30 pints then you're a bit of a sociopath.
Comment removed (Score:5, Insightful)
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The war on drugs never worked. What makes you think government can stop people from getting their hands on even more addictive things like fat and sugar?!?!?
Sure, ban the sale of the Big Mac and 44oz soda... People will just buy two 22oz sodas and two cheeseburgers instead. Portion control doesn't work when one can just double a regular order.
If you ban sodas and burgers entirely, well... I'll be outside grilling burgers from fresh ground beef and making my own sodas from seltzer water, sugar, and flavo
Science journalism (Score:5, Insightful)
In my mind, the "cure" mentality is linked up with a general problem with science journalism. I think there may be scientists who contribute to the problem in some way or another, and once silly ideas or bad information is out there, everyday people will spread it around, but it's primarily about journalism.
And the problem with journalism, as far as I understand, breaks down into two general causes. One cause of the problem is oversimplification-- either the journalist doesn't understand the science, or they don't expect that their audience will understand, so their explanation of the science cuts out a lot of the complications and gives a simplified explanation. That is not a problem in itself, but when you simplify, you run the risk of oversimplifying and ending up with an explanation that's actually misleading.
The other big cause of problems seems to be sensationalism. Journalists want people to read their stories and get excited about their stories. More people will be excited about a story about a "cure for cancer" than "a treatment for cancer that will meaningfully extend life in select cases." More people will be excited about a story about how "drinking coffee will kill you," than one about how "a single study indicates some adverse effects of coffee consumption, but more study is needed." More people want to read about "A new breakthrough that will make time travel possible" than how "A single scientist who's a little on the fringes is trying to develop a new variant of string theory, which if it turns out to be true, might possibly mean that time travel is theoretically possible but practically impossible and/or well beyond any technology we have. Or it might still mean that time travel is impossible. We don't know yet because the theory isn't complete."
The result is a lot of misinformation, and a lot of focus on the wrong things. One example might be a focus on "cures" when "treatments" may be more realistic. Another problem is an expectation of impending wild technological advancement. We read about someone developing a new technology for manufacturing processors or displays that will be give us super-gadgets in the next 3 years, when even if those advances materialize, they're 20 years out. Another problem is fad diets, since every study relating to diets is suddenly reported as a miracle that will allow everyone to shed all of their unwanted weight and become super healthy. Another problem is scifi concepts being reported as "just around the corner". In the next couple of years, we'll all be immortal, living with AI, time traveling, traveling faster than light, with unlimited perpetual motion machines generating all of the energy we'd like. It's always just a couple of years out, but never materializing.
Arguable the most damaging problem is that all of the other problems makes science appear to be complete bullshit. With the kind of ideas being pushed as "scientific", I almost have a hard time blaming people who disbelieve that pollution is bad, people who believe that homeopathy works, or people who are afraid of vaccinations are harmful. We're flooded with constant promises that are unfulfilled, and conflicting reports about things being "scientifically proven". One year, eggs will kill you, and the next they're a miracle cure for everything. A few years ago, we were all being told to replace fatty foods with sugar-filled substitutes, and now we're being told the opposite. If you see enough of those stories, I can understand not knowing who to trust.
Why? (Score:2)
Because it's easier to sell advertising on the news that "something better is coming" rather than "the same old treatment still works."
prevention...cure...treatment...diagnosis (Score:2)
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So why aren't we seeing cures come out of Scandinavia?
The health insurance companies are the ones who profit most from finding cures. This is especially true now that everyone in the U.S. is required to purchase private health insurance.....they can keep charging the same amount while spending less on treating the disease they cured.
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Exactly. They come out of the US and then Germans brag that their national healthcare system "stiff" the companies that went to the bother of developing the wonder drug.
Where are the socialist countries in all of this? Why aren't the stepping up? Why aren't they providing the free miracle cures?
The fact that there are any drugs for what I have, never mind the fact that new ones are being developed, blew my mind a bit.
We are too stupid to take vaccines to prevent (Score:2)
diseases, but we expect someone to cure them once we contract them, except for people who only pray for divine intervention. People are weird.
Because cures bring instant fame (Score:2)
It's tempting to argue that pharma companies have secretly given up on major cures because they make nore long-term money from ongloing treatments, but the major diseases are a worldwide problem and medical research is being done in numerous places not under control of Big $DEMON. A Chinese researcher who finds the cure for a major cancer has just as certain a Nobel as an American researcher.
And even in the context of American medicine, the fame attached to being a discoverer of that magnitude eclipses pecu
The cure culture? (Score:2)
"Disintegration is the greatest album ever!!"
-- kyle.. or was it stan?
The cure for cancer. (Score:2)
DCA cures most cancer. Not sure why it hasn't received more attention.
Same issue with EVs, and many other 'science' item (Score:2)
You guys act as if this stuff were simple... (Score:2)
At least as simple as computers.
For folks who pride themselves on rationality, you idiots are vastly underestimating the complexity of biological systems. It's almost like you have a model that biological entities were simple clockwork mechanism designed by a higher power or something.
Give up the irrationality and paranoia - sometimes cures are just far away. You want cures? Commit to the hard work they take to find.
Re:Good questions (Score:4, Insightful)
It kind of reminds me of the mindset that says people shouldn't live in single family dwellings and should instead live in high density developments. Or, don't own your own car, take public transportation. Or stay home for vacation. Or etc. etc.
It's the mind set that says, "You want A, but you SHOULD be satisfied with B".
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Always told to us, of course, by people who themselves live in mansions, travel via private jet, and are driven around in armoured SUVs.
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Nope. I've said it and I have none of that. Nice try trying to poison the conversation with a stereotype.
Re:Good questions (Score:4, Insightful)
And guess what: they are not all living miserable live because of that. At least in Europe, their day to day lives are nicer then they are in the US. Not having to get in a car and get stuck in traffic is a GOOD THING. If you don't feel that way, I suggest that you move to LA and get a job that is a three hour commute one way. On a good day.
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No. Instead you have to endure the same length commute but in a miserable over-packed bus or train where you are likely to get groped if you're the wrong gender.
If you want to not be trapped in a concrete jungle, you will still have to commute yourself by car.
There are no shortage of cars in Europe in general really.
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I assume you have never been outside the US. We are the exception, not the rule. Generally everyone else in the entire world takes public transportation and lives in multi-unit dwellings.
Hi. My sister lives in Alaska. The population density is one person every 2 square kilometers (1.3 people per square mile).
Where exactly should she go to catch the public transportation from her cabin, and into Barrow?
Thanks for any info!
(Validity of public transportation as an option is proportional to population density).
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1/4 acre lot, 2400st ft home, 6 minutes to work if i don't stop for breakfast tacos.
You do what you want, I'll do what I want.
So I suggest you STFU.
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Not really. If you just HAVE to live in the cool places, you'll need to be wealthy. Otherwise there are millions of nice places with good schools, jobs, opportunity, culture and you don't have to be making six figures to live there in your own home.
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Define rich. Our house cost about $200K when we bought it (FSM knows what it would sell for now) in 1999, and is nice and close to downtown.
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It may remind you of that, but it's not a very good comparison. You think that living in a city and taking public transportation is akin to suffering with a disease?
I'm someone who would argue, to some extent, that you shouldn't live in single family dwellings and you should take public transportation, but my argument is in no way, "You should be satisfied with those things." Or rather, I don't really care whether you're personally satisfied with those things as much as, I think we should allow people th
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Exactly. Why ruin a chance for profit. Diabetes is the drug company's wet dream. cannot be cured, requires constant medication but takes a while to finally kill you (enough time to really make some money).
people want cures, not treatment, because a cure means the problem is *gone*. Asides from not having to deal with the disease anymore, they don't have to worry about the side effects of the "treatment" (there are always side effects, and the treatments are never full solutions - both the side effects a
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"Diabetes is the drug company's wet dream"
But it's the health insurance company's worst nightmare.
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Exactly. Why ruin a chance for profit. Diabetes is the drug company's wet dream. cannot be cured, requires constant medication but takes a while to finally kill you (enough time to really make some money).
Well, any company that isn't making money from diabetes would still be interested in a cure. They don't care if some other company is making a profit.
As for "imprinted in the genes from birth to death" that is malarkey. Most of the genes in every person's makeup are never actually *expressed*,
The article is about cystic fibrosis. Cystic fibrosis is coded in the genes. End of story.
so the idea that because the potential for something is in one's genes means it cannot be suppressed is just silly.
Unfortunately, it's easy to say that just because it's in the genes doesn't mean it can't be "suppressed". But it turns out to be difficult to actually implement that.
This is a large part of what the actual article is written about: gene therapy sounds easy. But it isn
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Re: Good questions (Score:2)
Well.. the premise of the actual article is that a cure, if possible at all is a really long way out. The author gives some pretty good reasons as to why this is so. Meanwhile, people are suffering today. Better treatments are possible but all of the funding and hype on finding a cure is holding them back.
The article seems pretty anti-cure to me but near the end the author does call for a balance between cure and treatment research rather than completely giving up on the cure.
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With many diseases we are at the point where ANY progress is going to be non-trivial. Meanwhile, there are a number of recent wonder drugs that have been developed. They even get developed for obscure diseases you've never heard of.
I'm shocked that we have the drugs we do for all of the obscure shit you've never heard of. I'm amazed by it and how American capitalism already managed to find the incentives for them.
I think the whiners are ungrateful jackasses and a good example of why you should never give an
This is bullshit. (Score:2)
Better treatments are possible but all of the funding and hype on finding a cure is holding them back.
This is bullshit.
I think the major reason that the CFF is ignoring treatments is that any treatment which does not result in a cure is, by definition, an ongoing revenue stream for big pharma, and therefore big pharma has that angle covered: if they come up with a treatment that works, they have a customer for the rest of that customers life. And there is no incentive for big pharma to then work on a cure.
In fact, if you were to come up with a cure for something which represented a huge existing revenue str
Of course we should poke. (Score:2)
We just added two letters to the DNA sequence. Are you sure we should be poking about in there before we have a better understanding? This is not me being negative or dismissive. I truly do not know.
Of course we should poke.
The only way to learn is to poke.
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And why are we eschewing or overlooking treatments—real, honest-to-god treatments—that can let patients lead longer, more normal lives?
They take a pretty narrow view of "we". Once you get past the basic science phase of identifying the cause, the vast majority of funding and FTEs goes to researching treatments. Even though cures would be much more profitable for most diseases, it is very rare for cures to be attainable.
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Welcome to /. you must be new here...
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"People on raw vegan diets don't age."
Can you provide a reference for this?
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You're confusing anecdotes for science (assuming what they claim about their age and diet are true).
You can find lifelong tobacco smokers who are healthy into their 80s. That doesn't mean everyone who smokes is going to live healthy into their 80s.