New submitter Gunilla sends this news from an AP report: "It turns out this year's flu shot is doing a startlingly dismal job of protecting older people, the most vulnerable age group. The vaccine is proving only 9 percent effective in those 65 and older against the harsh strain of the flu that is predominant this season, the Centers for Disease Control and Prevention said Thursday. Health officials are baffled as to why this is so. But the findings help explain why so many older people have been hospitalized with the flu this year. Despite the findings, the CDC stood by its recommendation that everyone over 6 months get flu shots, the elderly included, because some protection is better than none, and because those who are vaccinated and still get sick may suffer less severe symptoms." An anonymous reader adds information about a new drug that treats influenza by hijacking its own infection mechanism. The compound "binds to an enzyme on the surface of the flu virus called neuraminidase. This enzyme is responsible for severing the connection between the flu virus and human cell so it can move on and infect other cells. The new class of drugs — DFSAs — permanently bind to the enzyme, blocking its action and stopping it from spreading further, the journal Science reported (abstract). Currently available antivirals also work by attaching to this enzyme. But DFSAs do so in such a way that the flu virus cannot evolve to be resistant to the drug without rendering itself useless."
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