Advances in Bio-weaponry 279
kjh1 writes "Technology Review is running an eye-opening article on how biotechnology has advanced to the point where producing bio-weapons that were once only possible with the backing of governments with enormous resources is now possible with equipment purchased off eBay. You can now purchase a mini-lab of equipment for less than $10,000. The writer also interviewed a former Soviet bioweaponeer, Serguei Popov, who worked at the Biopreparat, the Soviet agency that secretly developed biological weapons. Popov has since moved to the US and provided a great deal of information on the types of weapons the Soviets were developing."
at last (Score:5, Funny)
Re:at last (Score:3, Funny)
Re:at last (Score:2)
But given your particular hero... dude, you're boned. Go get a job flipping burgers at Sonic.
Re:at last (Score:2, Informative)
Re:at last (Score:2, Insightful)
Oh goody (Score:3, Insightful)
Re:Oh goody (Score:2, Insightful)
First, it was the Germans. After the U.S. kicked around Germany, they poached German scientists so that the U.S. could have access to all the interesting things the Germans had been working on. Rinse and repeat after WWII.
Then Soviet Russia collapsed and the U.S. took in mobs of poor, unpaid Russia scientists + the research that they've been working o
Re:Oh goody (Score:5, Insightful)
Everyone and his dog has access to bioweapon design and production capabilities. Once you have got your hands on a sample of virulent bacteria like Antrax producing them is a piece of cake. Viruses are considerably more tricky but it is still feasible to produce the less fussy ones with student lab level equipment. Actually with viruses your biggest problem would be isolation, not production.
So far so good, here everyone would ask why all the dictator wannabies and terrorists are not slugging each other with biowarfare?
Well the answer is simple, while producing bioweapons can be done in a garage, producing a viable delivery system is something much more difficult. Testing it is even more difficult. This is clearly beyond the capabilities of most terrorists and dictatorships out there. And thanks $DEITY, otherwise we all would have been walking around wearing filter masks and wearing biowarfare suits on public transport.
Re:Oh goody (Score:3, Informative)
Actually, IIRC this is not the case. While it's easy to cultivate Anthrax, it is very hard to "weaponize" it: mill it so fine that it will spread on air currents as an aerosol.
Which I take to be you point. But you make it sound like the hard part is putting it in some kind of warhead. That's relatively easy. It's not really any more complex than the IEDs they are using in Iraq.
"Getting it right"
Ten grand? (Score:5, Funny)
Re:Ten grand? (Score:5, Funny)
Re:Ten grand? (Score:2)
Why was I expecting a goatse link?
Re:Ten grand? (Score:2)
Re:Ten grand? (Score:5, Insightful)
Some way to aerosolize the resulting cocktail of anthrax and botulotoxin:
Re:Ten grand? (Score:2)
Re:Ten grand? (Score:2)
Re:Ten grand? (Score:2)
That's right! Had. Not Have.
Welcome to the real world baby!
Re:Ten grand? (Score:3, Funny)
This vision of subtle bioweapons that modified behavior by targeting the nervous system -- inducing effects like temporary schizophrenia, memory loss, heightened aggression, immobilizing depression, or fear -- was irresistibly attractive to Biopreparat's senior military scientists.
So how's that different from rush hour traffic in or around the Washington DC I-495 beltway loop? Seems our boys at NSA haven't got containment down just right yet.
worried? (Score:5, Insightful)
Aum Shinrikyo, a Japanese cult that had some three hundred scientists in its employ and an estimated budget of $1 billion, reportedly tried at least nine times over five years to set off biological weapons by spraying pathogens from trucks and wafting them from rooftops, hoping fancifully to ignite an apocalyptic war. These efforts failed to create a single fatality--in fact, nobody even noticed that the attacks had taken place.
Re:worried? (Score:3, Insightful)
By the end of that day, 15 subway stations in the world's busiest subway system had been affected. Of these, stations along the Hbiya line were the most heavily affected, some with as many as 300 to 400 persons involved. The number injured in the attacks was just under 3,800. Of those, nearly 1,000 actually required hospitalization--some for no more than a few hours, some f
Re:worried? (Score:4, Informative)
That was the first and only... (Score:5, Informative)
From wikipedia:
Sucessful dispersal of chemical and biological agents is tough. Government funded programs have not been very effective, what makes anyone think that terrorists could come up with an effective delivery system.
Re:That was the first and only... (Score:5, Insightful)
Re:That was the first and only... (Score:2)
Re:That was the first and only... (Score:4, Insightful)
I want to add an addendum that I personally don't lose sleep over the threat of a terrorist attack. More people die every day in car wrecks or from heart attacks than in any terrorist attack. While I eat a pretty healthy diet, I drive rush hour traffic every day and don't drive slow. My risk from that is about a thousand times worse than any sort of terrorist attack, especially if I were to figure in that I don't exactly live in a top 10 list of potential targets (or top 1000 for that matter). I just wish more people would think about the simple statistics instead of the "fear factor" and terrorists would be out of the proverbial job.
Nukes are a different thing entirely (Score:5, Insightful)
Making HEU is a very difficult task; Zippe-type centrifuges can't be put together in your back shed. More plausibly, they could steal it or buy it on the black market, but even that's going to be very difficult.
WMD's are a bogus category, in my opinion, draw a bogus analogy between nukes, which genuinely can kill tens of thousands of people at a shot without any great operational genius, and chemical and biological weapons, which seem to be very hard to make that lethal, even though theoretically they can be.
Re:Nukes are a different thing entirely (Score:2)
> a library card, and an electrician to make a nuclear weapon.
Or if you're MacGyver, the library card, a putty knife, and the game ball from the 1987 Superbowl.
Re:Nukes are a different thing entirely (Score:2)
Even so, the real threat is from national governments. It must be very tempting to the Chinese, for example, to deploy an IL-4 enhanced virus that only kills caucasians. Or vice-versa the USUK.
Re:Nukes are a different thing entirely (Score:2)
But not something a terrorist would do. Not showy enough probably.
Re:Nukes are a different thing entirely (Score:3, Insightful)
But you
Re:That was the first and only... (Score:3, Insightful)
I lose sleep over the political/societal reaction to the terrorist attack. You think that civil rights in this country were damaged by 9/11? Imagine what the response would be like to, say, Chicago getting hit by a tactical nuke. Sealed borders? Concentration camps? Apocalyptic cults? Economic crash? Fundamentalist/reactionary politics? I think the secondary damage would almost certainly outweigh the primary damage by an order of ma
Re:That was the first and only... (Score:2)
Re:That was the first and only... (Score:2)
Based on recent experience, our reaction would be to flatten some other nation, preferably one that's hostile to the actual sponsor, in the nearby region.
Re:That was the first and only... (Score:3, Insightful)
No. If you do that, there's going to be an endless line of recruits ready to give their lives in order to kill you in revenge.
If you want to stop terrorism, make sure that the potential terrorists have lots to live for - wife, kids, dogs, full stomachs, a comfortable and secure life. Misery feeds fanaticism, especially since you aren't giving up all that much by blowing yours
Re:That was the first and only... (Score:2)
Re:That was the first and only... (Score:2)
It's not a question of what I (or anyone) would want. It's merely a question of what the nation would do, and what the effects/costs would be.
Re:That was the first and only... (Score:3, Insightful)
This is so true. Look at Osama bin Laden. After 911, the USA took EXACTLY the actions which were his stated aims. I'm still flabberghasted that this worked, and that the population hasn't raised a single question about that. Then again, you would be surprised to find out that transcripts of the OBL tapes are not that easy to find.
Some info not in the wikipedia blurb (Score:5, Informative)
* The major failure with the attack was the lack of time to develop a good dispersal mechanism, as the attack plan was moved ahead of schedule because of the cult's impression that the authorities were going to act on them imminently. They had this impression on the basis of penetration of Japanese military and police sources. They eventually settled on liquid in bags getting poked with umbrella tips.
* The "specific targets" at Matsumoto were judicial magistrates whom the cult thought had a hand in the investigation against them. Seven died in that attack, incidentally.
* Aum was fricking scary with the amount of resources they had at their disposal. I remember a $300 million chemical weapons factory (operating completely above-board in Japan in broad daylight, just another chemical factory, had all its permits), and them staging a parachute raid on a JSDF facility using turncoat JSDF forces. Sounds like a bad anime, I know.
I wouldn't be sanguine about this. If you can get weapons grade sarin you can certainly develop a delivery system for it. Its not trivial but, hey, $300 million dollars has a certain way of making non-trivial problems seem a whole lot less daunting. We lucked out in a major way, in that with everything designed right for the attack (high-profile target with hundreds of thousands of people in an enclosed space) the cult made multiple errors (impure toxin, dispersal surface area the size of an umbrella puncture, etc) which minimized the casualties. There were other lucky incidents, too -- two Japanese station attendants soaked up the chemical in one car with newspapers, sealed it in plastic, and took it to the station room (I don't know if they had any idea that they were dealing with anything worse than a liquid mess, but both of them died for their troubles, which many people from exposure to that portion of the attack).
And, incidentally, remember the anthrax attack on the US and how the postal system and much of the East Coast essentially *shut down* with less casualties? Its difficult to overstate how much of the Japanese economy/government/everything is dependent on Tokyo and how dependent Tokyo is on their mass transit system. If you hit one car in Tokyo's inner loop with a lethal nerve agent tomorrow and then followed it up with a successful strike once a week for, oh, I don't know, two weeks? Three? That would be about as effective at causing economic damage in Japan as driving an airplane into a tall building of your choice in New York City.
Re:worried? (Score:2)
A couple of high schoolers [wikipedia.org] did better than that, try again.
Re:worried? (Score:2)
Re:worried? (Score:2)
Fine. You can stay unworried. Me, I'll worry. (Not to the point of staying up at night or damaging my health, TIA for your concern.)
Why will I worry? I won't go into details as to how I think it possible - though I do have good reason - but sooner or later someone will be able to replicate haemorhagic smallpox in their garage, and modify it so that current vaccines are useless.
So go ahead and be as unworried as you'd like. Your life, your decision.
Re:worried? (Score:2)
I fully support George W. Bush's plan to surreptitiously search all garages in order to find these evil people.
What? 9/11 changed everything, you know.
Re:worried? (Score:4, Insightful)
Re:worried? (Score:2)
Remeber the first bombing attack against the WTC? It was laughable how badly it was attempted. V 2.0 was 9/11.
This sort of thing is certainly something to keep an eye on - just because one group managed to fail repeatedly (except for the subway attack) doesn't mean every group will. This stuff is only going to get easier.
Re:worried? (Score:3, Insightful)
Well, yes and no. You are correct that the followers of Bhagwan Rajneesh hit upon a more effective delivery system when they simply sprayed salmonella salad bars. [att.net] But salmonella did not prove sufficiently lethal. Although they infected hundreds and hospitalized 45, nobody died. Antharx, OTOH could not have been deliveed by the same mechanism. There is a balance of deadliness, controlability and deliverability which is difficult to
Re:worried? (Score:2)
Of course, it's possible that that "help" was designed to retard their progress. At least, I'd like to hope we're that smart.
Weapons (Score:2)
The hard part is weaponizing them.
Re:Weapons (Score:2)
And that peroxide stuff whose name I can't recall?
Hydrogen Peroxide. Anything above 70% reacts with itself, and it catalyzes with any sort of organic substance (like oil and rubber). NASA likes it for rockets, and it's good for cleaning wounds at 0.5%. Dunno how to make it, but it can't be that hard - I found a recipe for Astrolite lying around, and that stuff is really interesting. If you really want to cause fatalities, you need look no further than swordfish - C4 + ball bearings hooked up to a proxim
Re:Weapons (Score:2)
Actually, this is the class of chemicals that I was thinking of. Nasty stuff, absolutely terrible.
Re:Weapons (Score:2)
Yecch. It looks like the a solid form of Acetylene, and I especially like the part where it sublimes into more and more unstable compounds.
Also check out Ken Alibek (Score:5, Informative)
Frankly, this is the stuff of horror stories.
Re:Also check out Ken Alibek (Score:3, Informative)
(The second link has an interview with Dr. Alibek)
National Raygun Association (Score:5, Funny)
...for Duck hunting!
Move Along (Score:4, Insightful)
Re:Move Along (Score:3, Interesting)
Keep in mind that this was a beginning bio class, at a junior college.
It's easy, it doesn't take a whole ton of education.
How did she do that? (Score:2)
Okay, I'm interested in exactly HOW she managed that. Particularly in a "beginning bio class" at a "junior college".
"genetically altered" means that the DNA/RNA has been changed. Why would she be doing that with a virus in a "beginning bio class"? What would the purpose be?
Particularly in a "beginning bio class" at
Re:How did she do that? (Score:2)
Just go grab a used DNA synthersizer [google.com], some spectography equipment and you're just about set.
Go read the article, it explains exactly how easy it is.
I didn't say the equipment wasn't affordable. (Score:2)
Yeah. Right.
So class, take test tube #1, put it in this device, press this button and you get this spectrograph.
Take test tube #2, put it in this device, press this button, then put it in the other device, press this button and you'll see the altered spectrograph.
So, what is the purpose of walking a
Re:I didn't say the equipment wasn't affordable. (Score:2)
And here's my last post on this thread. (Score:2)
There is no reason that what you claim would have happened and lots of reasons why it would not.
Re:And here's my last post on this thread. (Score:2)
It happened, regardless of you believing me or not.
It is trivial to genetically alter a virus or DNA.
Re:And here's my last post on this thread. (Score:2)
The point wasn't that we understand everything we were doing. The point was to get us interesed in the science.
Re:I didn't say the equipment wasn't affordable. (Score:2)
Re:I didn't say the equipment wasn't affordable. (Score:2)
Re:Move Along (Score:2)
Well, part of the reason it works is that you don't "accidentally" create weapons grade uranium/plutonium, not even in a regular nuclear power plant. Whereas "bio-weapon" research, you'll find the natural kind in any medical education or research facility. In worst case, send some of your boys to med school with focus on lab/science parts and you're off to
Now think about "mutation". (Score:3, Informative)
So the pathogen would have to target a very specific ... DNA/RNA sequence?
What happens when the pathogen mutates? Lots of little virus babies mean lots of chances for mutation.
Yeah, whatever. (Score:4, Informative)
Seriously, I'd expect someone with your claimed credentials to understand the basics of this. This isn't cut-and-paste.
You have to identify the exact DNA/RNA sequence that identifies your target.
Then you have to engineer the virus to only kill the hosts with that sequence
while remaining dormant in the hosts without that sequence.
And you can't just cut-and-paste the sequence you want to attack into the virus. The changes to the virus would be a completely different research project. And why would that person choose bio-tech over the conventional shotgun? Because chemical agents work so much more effectively, are easier to manufacture, transport and disperse.
And even more effective than chemical agents are conventional weapons. Such as "hand guns" or "shotguns". Not to mention the ever popular "explosives strapped to your body".
The talented before the ignorant. (Score:2)
Yeah, let's stick with that analogy.
Those 10 year olds aren't doing anything that wasn't done 10 years ago. They aren't doing anything that wasn't done 15 years ago.
By the time the skill requirements drop down that far, all of the viruses you've described would have already been created by peop
Re:The talented before the ignorant. (Score:2)
kiddies are a real problem. You are right about one thing: there is
no rebooting out of a bio script kiddie's masterwork. And no, by the
time we understand how to design viruses we will not have created all
of them. Besides, creating a virus and knowing how to kill it are two
different problems entirely, so even if some yahoo re-creates a known
virus, all that matters is whether there is a defense.
Now let me respond to your bullets, assuming that a
Re:Now think about "mutation". (Score:2)
region or food as a promoter of viral activity. TFA actually mentions
this in a different context, where they were using drugs administered to treat
one disease as a promoter for another - the point is that this is
generic and can potentially be exploited with chemicals other than
drugs.
My girlfriend just peeked over my shoulder... (Score:5, Funny)
Me: Er, because they're in the past?
GF: Huh?
Me: Um, the Soviet Union collapsed more than a decade ago. Didn't you know that?
GF: Get out of here! I thought China was still around.
Me: Honey, the Soviet Union is modern day Russia. Not China.
GF: What? I thought Soviets were commies, and the Chinese are commies.
Me: Yes, but the Soviets were Russians.
GF: The Russians are Chinese?
Me: No! NO! NOO!
GF: Jesus. You don't have to yell! I was just asking!
Me: Alright, alright, I'm sorry.
GF: So how do the Nazis fit into all this?
Me: NAZIS!? Are you pulling my leg?
GF: I'm not!
Me:
GF:
You can't make this shit up I tell you.
Re:My girlfriend just peeked over my shoulder... (Score:5, Funny)
Me thinks thou doth protest too much... (Score:5, Funny)
Your post caught my eye because it was really funny. Then I started to wonder what else you talk about in your posts.
Looking at your recent posting history I have found the following.
Negroponte says Linux too 'Fat' [slashdot.org]
Startup Webaroo to put the 'Web on a Hard Drive'? [slashdot.org]
Er, I'm asking this in order to, er, protect my girlfriend's sensibilities. Can't have her unwittingly downloading such naughty stuff you know. =)
Two Unofficial IE Patches Block Attacks [slashdot.org]
So many references to your "girlfriend" in so short a time aroused my suspicions so I decided to google for '"Dante Shamest" girlfriend' [google.com] and guess what I found.
THIS proof that you are a liar with no girlfriend. [cprogramming.com]
But...I don't.
You've been using the same bullshit ruse for over a year now. It's ok if you're celibate, but it's just plain pathetic to lie about having a girlfriend.
LK
Re:Me thinks thou doth protest too much... (Score:2, Funny)
Re:Me thinks thou doth protest too much... (Score:4, Funny)
Dante lying about having a girlfriend
You taking the time and bothering to unmask him
or me bothering to care about you nerds at all...
Re:Me thinks thou doth protest too much... (Score:2)
Re:Me thinks thou doth protest too much... (Score:2, Funny)
LK
Re:Me thinks thou doth protest too much... (Score:5, Funny)
Re:Me thinks thou doth protest too much... (Score:3, Interesting)
You made a good run of it, but the ruse is over.
LK
It's pretty easy now. (Score:2, Funny)
There are cheaper ways (Score:2, Funny)
Relevant Literature (Score:2, Informative)
spoiler alert (Score:2)
SPOILER alert
Yeah, I read that about a month ago. Not one of his best, but compelling. It has some thin psychological premises (pharmaceutical scientist driven mad with grief over the IRA bombing of his family becomes evil genius) and the science is pretty sketchy, even to a lay lumpen like me. Most of the book is taken up by Herbert's typical meditations on power and deception and violence as a way of life, but this time he goes on and on and
Invasion Target (Score:5, Funny)
How do you fit your tin foil hat... (Score:3, Funny)
benifit/cost (Score:5, Insightful)
So here is the rub. One not only has to have the equipment and expertise to create the biowepon. One also needs a way to infect people in lethal doses. And, to begin with, one needs to believe the bioagent will be more effecient than conventional weapons. Look at it this way. The allies probably did more damage in Dresden using conventional weapons that in Japan using nukes. However, the Japan attack was much more effecient, posed almost no risk to the Allies, had no real defense, and was not limited by the logistics of flying many planes. For a bioagent to be preferable, it must be like a nuke. If Bush is to believed the Iraqis have a bunch of biological agents, yet we see bombs are used more. Perhpas the Iragis to have WMDs, and bombs are just so much more effecient and dramatic. I mean proving to the US forces that defending against IEDs is hopeless to so mouch more dramatic than simply killing everyone in the green zone with lead poisoning, for instance.
This seems like another fear mongering article planted to create an impression that certain not-so-dangerous things are critical, so that the complex really dangerous things can be ignored. It just shows a true lack of imagination. I tink in most cases the villians just want the drama. That is why they blow up the building after it is evacated, instead of blowing up the location to which the people are evacuated to.
Re:benifit/cost (Score:2)
Indeed. Not to get all tin-foil-hat about it, but what was the deal there? Why was (what appeared to be) the US government's anthrax being mailed to people in the months after 9/11? And why did the government investigations of it turn up absolutely nothing? Seems awfully fishy to me.... like perhaps it was part of a "psy-ops" operation to scare the public into supporting a
The real threat is lower tech (Score:3, Interesting)
Affordable science tools is a GOOD thing! (Score:2, Insightful)
Cheap scientific tools means more tools in the hands of science tinkerers.
The more science tinkerers, means more interest, innovation, and new businesses in science.
THIS IS A GOOD THING!
If science tinkerers with affordable tools can get an open-science movement going (like programers have done with open-source), then we have a very bright future ahead of us.
FUD, like the mentioned article, are simply words of someone
Popov? (Score:3, Funny)
Scientists and Public Responsibility (Score:3, Insightful)
In the classic days of Leonardo da Vinci, the Renaissance Man was the master of everything and was on top of many topics of interest. However, many modern achievements have been realized through specialists - science, engineering, agriculture, arts, etc... It would not be fair for a world-class scientist to be responsible for establishing the policy guidelines of a new technology. Their main concern is and should be to advance the frontiers of science - their opinions should carry weight regarding policy, but in general they are not adept with such responsibilities.
In the absence of an appropriate entity with this responsibility, the lack of oversight may lead to unwanted outcomes. Einstein's revelations made the atomic bomb feasible, yet afterwards Einstein was one of the biggest opponents of nuclear arms. As someone who is in biotechnology, I know that we may have social responsibility on the back of our minds, but in the forefront is finding that discovery before someone else in our field finds it first!
Bill Joy and others saw this years ago (Score:3, Insightful)
http://wired-vig.wired.com/wired/archive/8.04/joy
The big quesiton is: why aren't the intelligent, well-educated, technically minded of the world actually taking issues like this seriously, and doing something about it? Probably because thinking about this stuff means questioning one's own vocation and existence, and perhaps discovering that the blind pursuit of scientific knowledge or development of technology can have just as many unintended bad consequences as good ones. We can't stop these pursuits; nor should we. But all who are involved in these pursuits must also assume responsibility for analyzing the risks of their application.
Bill Joy called for a "Hippocratic Oath" of sorts for scientists and technologists to take responsibility for the ethical concerns as well as the scientific or technological or design concerns. We already know how to assess some forms of risk. These are just different kinds of risks to be assessed, and they are real.
If we are as good and as smart as we think we are, how can we not step up?
Re:Bill Joy and others saw this years ago (Score:5, Insightful)
This isn't like a video game where you need to go down the 'horrible biological weapons' research tree in order to get horrible biological weapons. The same technology that lets you engineer a crop that can end world hunger or create new organs from scratch is the same path that leads to horrible weapons. You can't simply pick the good over the bad. By advancing forward you WILL uncover the bad and make available the tools to do terrible things. The only option you have left is to either grind to a technological standstill or simply do your best to fend off dangers as they come.
The only way to stop technology is to put in place a world wide totalitarian government that ruthlessly enforces 'sustainable' living and the freeze of technology. By "sustainable", I don't mean the crunchy American tree hugger version that involves eating a lot of soy and riding a bike while still enjoying central heating and electricity. I mean brutal Maoist style raw utilitarianism that merrily sheds lives in favor of the higher goal of a "sustainable" society out our present technology level.
This of course is an utter impossibility. Our system is like a shark. It moves forward or we all die. No little tweaks on society is going to make it so that we can maintain this state of technology forever. We will run out of resources and technology will either have an answer waiting or everything collapses.
The only answer is to cross your fingers and hope to hell that a Kurzweil utopia is right around the corner. The best thing we can do now is try and build defense when it is possible and blindly sprint forward hoping to hell that somewhere along the way an answer jumps out before something terrible happens.
Re:Bill Joy and others saw this years ago (Score:3, Interesting)
I think of two reasons when asked this question:
1) I have to spend, minimum 8+ years doing focused study in one area of knowledge just to get to the fringes of the body of knowledge in which I will be developing technology in.
2) I have to take all of those 8 years of knowledge condense it into a catch phrase of 2-10 words which explains the problem to people not
Axiom for the times (Score:2)
Also attributed to Commedian Emo Phillips
Re:Popov? (Score:2)
Re:Popov? (Score:2)
Re:Popov? (Score:2)
Re:Obligatory (Score:2)
That IS one Hell of a biological weapon... (Instant, irreversible blindness)
From TFA... (Score:2)
This is just another cobblestone in the Road to War.