Retina Blood Vessels Predict Common Fatal Diseases 128
An anonymous reader writes "LiveScience is reporting that Tien Wong, of the Center for Eye Research Australia at the University of Melbourne, is claiming that abnormalities in the blood vessels of the retina can be used to predict diabetes, hypertension, stroke, and heart disease. These results were the culmination of several large studies. This could go a long way towards advancing medicine in the developed world as these disorders are some of the most common causes of death, hospitalization, and disability."
A diagnostic boon . . . (Score:3, Insightful)
Re:A diagnostic boon . . . (Score:1)
Re:A diagnostic boon . . . (Score:4, Insightful)
The obviously better solution is a public health care system.
Re:A diagnostic boon . . . (Score:3, Insightful)
Many insurance companies actually don't make all that much money (compared to other businesses). Warren Buffett has a large amount of insurance companies under Berkshire Hathaway and their purpose isn't generally profit (though a few percent is nice) but for him it's basically an interest free loan called float. M
Re:A diagnostic boon . . . (Score:1)
Well, they seem to be doing alright in Canada [www.cbc.ca].
They respond to criticism of their earnings by stating that some insurance products are more profitable than others; overall though, profits look good [www.cbc.ca].
The best thing a consumer can do is, as you said, shop around.
Understand the 'benefits' you're paying for; if your auto policy covers you for 80% of your net lost income, can you survive on that? Does your life insurance/travel/medical cover
Re:A diagnostic boon . . . (Score:2)
Re:A diagnostic boon . . . (Score:4, Interesting)
Re:A diagnostic boon . . . (Score:3, Interesting)
Re:A diagnostic boon . . . (Score:3, Insightful)
So if the average "losing" bet against yourself with insurance would cost you an extra 10% over your lifetime, once you factor in the 40% negotiated discount, insurance SAVES you money.
Ins
Re:A diagnostic boon . . . (Score:2)
Why shouldn't insurance companies take the same risks they have always taken? This new technology does nothing to increase the incidence of any disease, which would cost the insurance companies money. Predictive tools give people the chance to do preventative things, which actually lowers the insurance companies' risk without leaving anybody out in the cold. Everybody gains from it.
Using this information to blacklist people lowers the
Re:A diagnostic boon . . . (Score:1, Troll)
Only in the few remaining rather backwards countries that don't actually have proper socialised healthcare.
Re:A diagnostic boon . . . (Score:1)
Re:A diagnostic boon . . . (Score:3, Insightful)
Nothing is wrong here, they're just preparing to patent this technique.
Re:A diagnostic boon . . . (Score:2, Funny)
Haven't any of you seen Gattaca ?
Re:A diagnostic boon . . . (Score:1)
Re:makes sense (Score:2, Funny)
The eye is the one place where you can see nerves. (Score:4, Interesting)
All this is from a $80 ophthalmoscope that you can fit into your pocket. As other posters have pointed out, this is pretty much old news.
Re:The eye is the one place where you can see nerv (Score:2)
As a dog breeder, I'm rather more accustomed to looking at retinas than the average non-medico, thanks to peering over the ACVO's shoulder during routine eye exams on my breeding stock (since there is hereditary blindness in dogs). An oddity I and my vet ophthalmologist have both noticed: in the Labrador Retrievers of 25 years ago, the typical tapetum in black or yellow specimens was a rich royal b
No, really... I'm not in poor health... (Score:5, Funny)
Re:No, really... I'm not in poor health... (Score:3, Funny)
This is not funny. (Score:2)
alot of tweakers tend to either drop dead or go pschyo after being up for 7 days.
Re:This is not funny. (Score:1)
Now, now... The original post was a joke, and so was the followup. Let's not get into a drug-based dick-sizing competition.
Re:No, really... I'm not in poor health... (Score:1, Funny)
Opthamologists knew this already... (Score:5, Informative)
Nevertheless this is a good nonintrusive way to diagnose someone.
Re:Opthamologists knew this already... (Score:4, Insightful)
I've been seeing the same eye doctor for about as along as I can remember (since I was young) and they've had me marked down as a high-risk patient for a long time.
I know my eye doctor is one of the top opthamologists in the state and it is a huge relief to know you're getting top notch medical care.
P.S. For anyone trying to find a new eye doctor, take into consideration the # of old people the doctor sees. The more old people, the more eye & health problems the doctor sees and deals with. Just a suggestion.
Re:Opthamologists knew this already... (Score:2)
But having it tested by a serious study is still better than relying on anecdotal evidence. So, thumbs up to the guys (and gals?) who organized that research
Iridology (Score:1, Interesting)
It would be interesting to look back in 20 years and see if they got anything right, or if they were a bunch of loons afterall.
I believe that the eye can show us much more than we currently think it can, it is just a matter of sorting through the
Re:Iridology (Score:2, Informative)
Re:Iridology (Score:1, Interesting)
Re:Iridology link (Score:2)
Retina based biometric security and privacy. (Score:5, Insightful)
Re:Retina based biometric security and privacy. (Score:2)
While this is a good thing for your ocular (and general) health, presumably such info *could* be acquired and misused by a malicious gov't, by someone bent on beating a biometric ID system, etc.
this has been done for years!!! (Score:5, Informative)
Microhaemorrhages (bleeds) and aneurysms (a bulging section of a vessel) may be present due to hypertension in the vessels because of diabetic changes to the retinal vessels, or systemic hypertension. Having more blood vessels than usual indicates that the existing ones are not supplying enough oxygen, as will be the case in advanced diabetes. Changes in the macular (the part of the eye that sees most detail) can be apparent if the diabetes is causing problems with vision.
Stroke, heart disease, hypertension and atheroscelerosis are all intimately linked anyway - people at risk of one are often at risk of others. And it's difficult to characterise the changes to a specific cause. But they're still an important thing to look at.
Another time a doctor will look at the retina, is in an emergency situation where the is a blow to the head, they'll look for papilloedema (a swelling behind the retina due to increased pressure inside the skull). This also happens with other causes of high intracranial pressure, such as tumours.
Re:this has been done for years!!! (Score:3, Funny)
P says "I've got the runs"
D says "Alright let me just have a look in your ears. Yup, you've got the runs."
Do they all just have ear fetishes or something?
Re:this has been done for years!!! (Score:3, Funny)
Re:this has been done for years!!! (Score:1)
Re:this has been done for years!!! (Score:1)
Why check ears? To see nasal infection/congestion (Score:4, Informative)
When I look in the ears, I can see whether there is fluid behind the eardrum, and tympanic bulging, which tells me that the eustachian tube (and therefore the nose) is plugged. If it is, then I can predict that the patient will probably have the sinus/eye/cough symptoms mentioned above. So the conversation would be more like:
P: I've got a cough and a headache.
D: Let me look in your ears. Yup, you've got a cough and headache.
By the way, about half my patients don't believe me when I tell them about their nasal congestion, because there's no mucus running out the nostrils, and their nose is unplugged enough so that they can breathe ok. Doesn't mean the eustachian tube's not blocked.
Re:this has been done for years!!! (Score:1)
IMO, that doesn't sound so bad...Certainly preferable to something like this:
P says "I've got the runs" /*puts on latex gloves*/....
D says "Alright, drop your pants and bend over
but... (Score:2)
Re:this has been done for years!!! (Score:2)
Well, that answers Col. O'Neill's question in "Window of Opportunity", "I ask you, what could possibly be in my eye that could explain all this?"
Hypertension (Score:1)
Re:Hypertension (Score:2)
One test for everything? (Score:1)
Is the complication that these markers don't exist in blood, or that we don't have the technology to pour some blood into a machine, thin it out onto a scanning su
Re:One test for everything? (Score:3, Insightful)
For one thing, the tests are difficult to do. Many of the most interesting factors are peptide hormones and proteins, for which it is difficult to design tests. Microarray scanners, which look at an array of fluorescent dots that each detect a different molecule, should begin to make a dent in the problem, but the going will be slow. One difficulty is th
Re:One test for everything? (Score:3, Informative)
First, you need to identify the disease you're looking for.
Next, you go to the lab and spend lots and lots of time looking to develop a test that is both sensitive and specific for that disease.
A couple of definitions:
Specific - Only picks up that disease (in reality, a test with a low false positive rate)
Sensitive - Able to detect that disease every time it's there (a low false negative rate)
Take prostate cancer for example.
In laymans terms many peop
Re:One test for everything? (Score:2)
Goes to show how a one-result-fits-many-possibilities test could go completely awry
Re:One test for everything? (Score:1)
Blood can tell you an awful lot about what's happening in the blood. Something like a leukemia will be obvious when there are way too many
Quit looking for a blood test that answers all! (Score:5, Insightful)
Good grief. Sorry, you've pushed a button in me; I get this request from my patients all the frick'n time, so maybe if I answer this one, it will save a lot of doctors (and patients) some trouble.
Why don't we just do a "blood test that checks for everything"? The short answer that "there is no such test", but then my patient asks for a CT scan or MRI scan, or wonders when we will be technologically advanced enough so that we can invent such a test. It will never happen. Here's why:
Each test result is imperfect and must be interpreted in light of the clinical context. In other words, you have to know what you are looking for, or else you won't be able to tell what's normal or not normal. I view each test as being a somewhat inaccurate answer to a Yes/No question, e.g. "Is it Horrible Disease X?", but there is no test that tells you, "What disease is it?"
Just casting a net far and wide, looking for "everything", will net you all sorts of useless false positives that will waste time, cause worry, and worst of all, result in further unnecessary testing that may be risky.
There are two main reasons for this: test accuracy, and test relevance. Let me illustrate:
Elderly men everywhere are demanding to have their Prostate Specific Antigen (PSA) blood levels checked, because it's not as embarrassing as having the doctor stick his finger up the bum to feel the prostate. Hey, you gotta check the PSA, because --what if you have cancer!!?? How can you be SURE that I don't have prostate cancer, doctor? (Answer: you probably do, and the prostate cancer will kill you in 135 years.) PSA testing is still controversial, and in fact the Canadian task force actually labeled PSA testing as harmful because then you need to surgically sample the prostate, leading to the risks associated with minor surgery.
How about that? A test that's actually harmful, hmm? You'd think you could just ignore the test result if that were the case, but nooo... now there's a medicolegal obligation to follow through with prostate biopsy.
On the other hand, if you carry a high risk for prostate cancer, then the PSA is a very useful test. If your father and his father and his father all had (clinically significant) prostate cancer, then I would definitely get you a PSA without you asking for it.
There's a mathematical basis behind this, so let me illustrate.
Suppose there's a Horrible Disease X that everyone is afraid of. Let's say it's HIV/AIDS, which some 1 million people have in the USA, but this applies to any other disease.
Suppose I have a test that is 99% sensitive; that is, if you really do have Disease X, then only 1% of the time will the test erroneously say that you are okay. The test is also 99% specific; that is, if you DON'T have X, then only 1% of the time will the test erroneously say that you do have it.
I need a volunteer from the USA population to try my Super Duper Get-Checked-In-Case-You-Have-X test. You there, with the Slashdot username "lifeisgreat", why don't we try it on you?
Horrors! The test is positive! Life is not great, after all! What's the chance that you have Disease X? What's the probability that my Super Duper test, with 99% accuracy, is wrong?
Think out your answer before reading on. You have just tested positive for one of those "every imaginable things" test that you were asking for. What will you do now? Call a doctor? Talk to family? Write a will? Will you ever live to have kids? Will you ever get frist psot on Slashdot again?
The answer: there is les
Re:Quit looking for a blood test that answers all! (Score:2)
Re:Quit looking for a blood test that answers all! (Score:1)
Asked another way, would it HELP or HURT you as a doctor if you could know the contents of a patient's blood down to molecular counts compared to population baselines.
Your rant makes it sounds like you would rather no improvements ever be made in blood testing technology. Why exactly I'm still not sure, but it sounds li
Re:Quit looking for a blood test that answers all! (Score:2)
Re:One test for everything? (Score:2)
How Do You Do It? (Score:1)
Re:How Do You Do It? (Score:1, Insightful)
Re:How Do You Do It? (Score:2)
Re:How Do You Do It? (Score:1)
How do you do it, and how do scanners do it? (Score:2)
Just a thought...
Re:How do you do it, and how do scanners do it? (Score:2)
Re:How do you do it, and how do scanners do it? (Score:2)
Re:How Do You Do It? (Score:1)
The quality's not good, but you can get interesting pics from a Digital Blue QX5 microscope held to your eye. With the 10x lens, and using the microsope hand held, you can see a fair bit of the inside of your eye.
Re:How Do You Do It? (Score:1)
beauty (Score:1)
Common Knowledge (Score:1)
Chinese Medicine (Score:4, Informative)
This is text book Chinese medicine. Looking for signs of these things in the face and eyes has a history of about 1500 to 2000 years. I guess it is good that Western medicine has finally come around, but this is far from amazing.
Re:Chinese Medicine (Score:4, Insightful)
I agree to a point - but Chinese medicine is overrated. Many more affluent Chinese turn to "Western-style" medicine these days when they have something serious.
For every 1 thing they had correct, there were at least 100 things that were useless or worse. That's the problem with something based in tradition without the scientific method to question it: "wisdom" get passed down through the generations, most of it never questioned.
As a western corollary: just think about the mountains of homebrew cures everybody suggests for a hangover and then go over how many actually work.
Re:Chinese Medicine (Score:1, Insightful)
No, I am not saying Chinese Medicine is the answer for everything but western medicine certainly does not hold the best key to fighting disease. If anything, it is western medicine that is overrated.
Re:Chinese Medicine (Score:2)
Link? References?
I'm skeptical, as that's a very big claim - "all" who took Chinese medicine. I doubt all the practictioners of Chinese Medicine would even take/prescribe the same herbs, much less that something like this won't make the news. Hell, China would be trumpeting it as propaganda (and rightly so).
Re:Chinese Medicine (Score:2)
I was talking about diagnosis and not cure. Western doctors generally cannot detect non-life-threatening problems with the body during an examination.
For instance, liver cancer is supposed to be extremely lethal according to Western doctors. I cannot remember exactly, but when my friend died of it, somebody told me that people diagnosed with liver cancer die something like 80%-90% of the time. The test results that showed my friend who died had liver cancer did not come back until after he had slipp
Go Vegan (Score:1)
Re:Go Vegan (Score:2)
Re:Go Vegan (Score:2)
Re:Go Vegan (Score:2)
Re:Go Vegan (Score:1)
Re:Go Vegan (Score:2)
oriental medicine (Score:1, Redundant)
This article seems to support the idea that there is scientific
So? (Score:1)
it's a quantitative technique (Score:1)
thats nice (Score:2)
By the time you exit the ID station, an annucniator can tell you your fate as accurately as a doctor or a fortuneteller:
Robotic Male Voice: "Good morning Abdulla Massoud You are on our no-fly list because we suspect you want to blow yourself up and take a few others with you." followed immediately by
It's already being done... (Score:3, Informative)
I AM a retina doctor ... (Score:4, Interesting)
Anyways, as many others have noted, this concept is really not new at all. The fact that examining the retina can clue us in to systemic disease has been around for over 100 years. The novelty here, I believe, is that the researchers have prospectively (I'm guessing from the context of the article) examined digital fundus photographs, and found that they can be used predictively in determining the risk of diabetes/hypertension etc... (essentially, diseases that preferentially affect the small vessels in the body). But even this doesn't seem that novel, I can personally recall reading an article about 5 years ago which specifically looked at examining digital photographs to screen for diabetic retinopathy.
The other interesting part of the article has to do with their work on setting up a web-based digital review center. While the idea sounds great, this type of telemedicine runs into a lot of logistical problems, a sample of which would include:
-Limited sensitivity - ocular manifestations of systemic disease are not always present, and certainly are often NOT present early in the disease course. If we give high-risk individuals a "false negative" reading, are we really enhancing their overall health?
-Medical liability - who would be reading these? A trained physician? Licensed where? I am trained in the US, and fully licensed to practice, yet I can't even cross a state border and perform an exam without breaking the law.
-How are the digital images supposed to be obtained? Digital funduscopic cameras are pretty expensive.
-Practicality -- let's see, I could either buy a digital imaging system, and submit a photo to a website for review, or I could just check this patient's blood pressure, in the office (or check a blood sugar, or cholesterol level, etc...). These tests are actually much more definitive (we check patient's blood pressures in the office, before a retinal exam!), than an eye exam.
Ideally, what would probably be more effective would be something like a software package that can automatically analyze these images (with the proper legal disclaimers, of course), bundled with a portable digital imaging system. These would be wonderful for something like large scale screenings of under-served, high-risk populations -- an indian reservation, for instance. Then, you could identify especially high risk individuals, and recommend follow-up with either an ophthalmologist or internist. Though, really, everyone should probably at least have an occasional screening physical by a real doctor (ok, ok, enough soap-boxing).
This reminds me of Elementary school... (Score:2)
Re:This reminds me of Elementary school... (Score:2)
When I was a kid (and sometimes to this day
Not news (Score:1)
The next movie... (Score:1)
Woman: "No, no, I won't hear it."
Man: "Look into my eyes. I'm dying."
Woman: "No! It's diabetes, I can see it!"
New lines! (Score:1)
"When I look into your eyes, I see Diabetes."
Great optometrist (Score:1)
There's nothing quite as surreal as looking into pictures of your own eye...
Is this really news? (Score:2)
Omega 3 (Score:2)
Here's your start up idea... (Score:1)
So much of medicine is plumbing and pipes. If pipes are clogged in one area of the body (the retinas), pipes are going to be clogged in another area (the heart, or the brain). This isn't a revolutionary concept.
What would be revolutionary is using image recognition algorithms to look for specific disease patterns in retinal vasculature. It is then a simple process of imaging the retinas and automate the image processing. That would give you a list of risk factors, and be able to direct additional scree
Old - new secret? (Score:1)
The eye has blood vessels in front of the retina that the brain has to interpolate out of the image - rather puts a wrench in the ID claim that the eye is an example of "intelligent" design - similar to having power supply wires in between the lens and sensor of a digital camera.
Good doctors also will take your blood pressure on both sides and use seve
A diagnostic boon (Score:1)
We are not exactly dealing with The New England Journal of Medicine here. The first thing you see on the site is an invitation to visit the Li
Covered By Insurance and Is In Use Across the USA (Score:1)
Retina vessels and disease (Score:1)
Iridology studies the iris not the retina (Score:2)
Re:Take your psuedoscience elsewhere please (Score:1)
Yes, that is, if one considers the iris and retina to be the same thing but this is hardly anything as occult as Chiromancy.
Re:a woman's eyes (Score:1)