Brain Surgery Patient Trapped in a Mental Time Warp 338
diverge_s writes "BrainConnection has an interesting article about a man who lives life straight out of the movie Memento. FTA: "When twenty-seven year old Henry M. entered the hospital in 1953 for radical brain surgery that was supposed to cure his epilepsy, he was hopeful that the procedure would change his life for the better. Instead, it trapped him in a mental time warp where TV is always a new invention and Truman is forever president. The removal of large sections of his temporal lobes left Henry unable to form any new personal memories, but his tragic loss revolutionized the field of psychology and made "H.M." the most-studied individual in the history of brain research.""
On the bright side... (Score:5, Funny)
Re:On the bright side... (Score:5, Funny)
I'm now wondering if he's been employed as a slashdot editor, and every dupe is a fresh exciting new story.
Re:On the bright side... (Score:5, Interesting)
Big bang special effects... (Score:2)
Back then people seemed to be much more sensitive to these things than we are now...
Re:On the bright side... (Score:2)
Re:On the bright side... (Score:2)
Re:On the bright side... (Score:2)
Re:On the bright side... (Score:2)
-
Re:On the bright side... (Score:2)
I lived through that horror. Where do I sign up?
On the bright side... (Score:2)
But, OTOH, did the surgery ended the Freaking seizures?
Re:On the bright side... (Score:5, Informative)
If you want to really dig into his case I'd suggest the following review paper that summarizes alot of the interesting things we've learned because of him much better than TFA does IMO:
http://homepage.mac.com/sanagnos/corkin2002.pdf/ [mac.com]
Re:On the bright side... (Score:2)
In other news (Score:5, Funny)
Re:In other news (Score:4, Funny)
Clive Wearing... (Score:5, Informative)
Re:Clive Wearing... (Score:2)
Re:Clive Wearing... (Score:2, Funny)
A bit more about him (Score:5, Interesting)
Re:A bit more about him (Score:5, Interesting)
She even learned how to sneak out and buy beer, and did so repeatedly. We were all impressed by that one. Of course, she pled innocent, and as far as she knows she was.
Re:A bit more about him (Score:2)
I think that this says something about human nature, but I'm not quite sure what ;).
Re:A bit more about him (Score:2)
What smoking and having those "bad" habits only do is make the last few years of your life miserable, not simply end it.
What doesn't kill you, at that point, just makes life harder to live. But it all comes down to the 'tude. My cousin's grand-father lost eyesight in the middle of both eyes. He can still sorta read, drive and all that stuff. But anything in the middle of his vision is simply blank. I needed to tell him who I was for him to recognize me, jus
Re:A bit more about him (Score:3, Funny)
I wouldn't deny her it.
Re:A bit more about him (Score:4, Interesting)
I'm really sorry to break this to you, but the last few years of your life are likely to be miserable and painful anyway.
I know it is very comforting to believe that you can avoid this by living healthily, but you are still going to degenerate and die. And that process is not necessarily going to be more comfortable just because you ate tofu all the time and never passed up an opportunity to whine about someone smoking a cigarette 50 feet away from you.
If there is a God, I strongly suspect that He has a very dark sense of humour. Leading an excessively healthy life probably counts as provocation.
Re:A bit more about him (Score:5, Informative)
so that means (Score:2)
"you cannot teach him facts about a bicycle that he doesn't know, but he could learn to ride a bycicle, if he doesn't know how"
So you could teach him to ride a bike but he'd be unable to to remember that he can ride a bike? Now that would be a weird experience.
Re:A bit more about him (Score:3, Interesting)
One would wonder then, if someone who was deaf had the same thing happen, how their memory would be affected? Because teaching them facts would involve using ASL, which you think would be equated with the motor memory.
Re:A bit more about him (Score:5, Informative)
A bit about my boyfriend (Score:5, Interesting)
In the weeks afterward, Andy had some fairly classic stroke symptoms, including paralysis on his right side. He couldn't talk, even to say his own name. But he could sing songs with people, because that skill is located on the right side of the brain, rather than on the left side with our language centers. And when his nasogastric feeding tube was pulled out, he spat out a very intelligible "fuck". Evidently swearing becomes a reflex.
While he was still recovering the ability to stand and to walk, he had to be watched all the time, because he'd keep trying to get up out of his wheelchair... unsuccessfully. But the fact that he kept trying to use his right arm and leg - not remembering that they didn't work - probably helped their recovery.
Every time I talked to Andy, I'd tell him about my new apartment; he'd usually - but not always - react with surprise. During one phone conversation (which wasn't going very well because he was distracted by the TV in front of him), I asked if I could talk to his father (with whom he was staying). Andy put down the cordless phone, saw that Dad was busy, looked up at the TV... and forgot I was there. I had to yell from the sofa cushion to get his attention, so he'd pick up the phone again. Conversations were always difficult because "what did you do today?" would elicit either shrugs or he'd just make something up, his mind grasping at any random memory that might serve as an answer. I frequently fell back on retelling him the same stories about my life lately, just to fill time and stay connected to him, and hoping that maybe they'd sink in.
He did gradually form some new memories. His therapists accomplished some of this by chronic repetition. Living in an environment with lots of calendars and repeated quizzes about the month and year, he got fairly good at remembering that. By asking him over and over during our drive home from a restaurant what the name of it was (no, he didn't find it annoying; each time I asked he barely remembered that previous time), he was able to remember it an hour later. Once, in response to me commenting about my shitty finances, he commented about "the new apartment". After several months of telling him about the fact that I'd gone back to college for another degree, he seemed surprised when I mentioned it again, but on a hunch I asked him what the name of it was, and he remembered. But for the most part, he learned to compensate for short-term memory with habits and with a lot of clever guessing.
I wish I could tell you about Andy's condition in the long-term, but his family won't let me see or talk to him anymore. (They say he'd get overstimulated and unmanageable after I visited or called on the phone... and I never got along that well with them to begin with.) I fought this at first, but since they're better able to care for him (they have money and a support network; I'm just me and underemployed), and since he's painlessly unaware that I'm not in his life anymore (for all he knows, he might have just seen me yesterday), I finally had to let go. More of the personal sob-story details can be found here [toddverbeek.com].
That man today... (Score:5, Funny)
Ah, come in. Now what seems to be the matter? (Score:5, Funny)
Boniface: Good evening. Tonight on 'It's the Mind', we examine the phenomenon of déjà vu. That strange feeling we sometimes get that we've lived through something before, that what is happening now has already happened. Tonight on 'It's the Mind' we examine the phenomenon of déjà vu, that strange feeling we sometimes get that we've
(Cut to opening title sequence with montage of psychiatric photos and the two captions and music over. Cut back to Mr Boniface at desk, shaken. Caption on screen: 'IT'S THE MIND')
Boniface: Good evening. Tonight on 'It's the Mind' we examine the phenomenon of déjà vu, that strange feeling we someti... mes get
(Cut to opening titles again. Back then to Boniface, now very shaken. Caption on screen: 'IT'S THE MIND')
Not news... (Score:3, Insightful)
If the most recent development was in 1953, is it still news?
Re:Not news... (Score:5, Funny)
Re:Not news... (Score:2, Funny)
You have to ask this on Slashdot?
Mirror, mirror (Score:5, Interesting)
Re:Mirror, mirror (Score:2)
I salute you
Re:Mirror, mirror (Score:2, Interesting)
Re:Mirror, mirror (Score:2)
Crueler still... (Score:5, Funny)
Re:Mirror, mirror (Score:4, Informative)
Fortunately, the doctor realized his error quickly, took away the mirror, and said, 'It's complicated, but I can explain it to you. But first, come on over to the window'. After looking out the window for a bit, HM forgot why he was there, or even that he was upset.
Re:Mirror, mirror (Score:2)
Re:Mirror, mirror (Score:5, Informative)
Errr, did you read the article? He doesn't appear too bothered by the mirror thing:
"Mainly, though, he leads a life of quiet confusion, never knowing exactly how old he is (he guesses maybe thirty and is always surprised by his reflection in the mirror) and reliving his grief over the death of his mother every time he hears about it."
Actually he seems quite upbeat about the whole thing, the highlight of the article for me (as it looks like you probably missed it) has to be the following:
When walking down the corridor at M.I.T. with Henry, Dr. Suzanne Corkin made the usual kind of small talk. "Do you know where you are, Henry?"
Henry grinned. "Why, of course. I'm at M.I.T.!"
Dr. Corkin was a bit surprised. "How do you know that?"
Henry laughed. He pointed to a student nearby with a large M.I.T. emblazoned on his sweatshirt. "Got ya that time!" Henry said.
Haydn.
Re:Mirror, mirror (Score:3, Funny)
Just how the hell did I become 35?
The real question is... (Score:2, Funny)
What would Adam Sandler do?
Re:The real question is... (Score:2, Funny)
Re:The real question is... (Score:2)
* scribble scribble scribble *
"He is the one. Don't believe his lies. Kill him."
Result!
I never considered surgery (Score:5, Interesting)
The brain has a fantastic ability to route around damage, but 53 years after this man's surgery, we still don't know enough about the way it works to reliably fix problems that the brain itself cannot handle.
(Then again, my seizure episodes aren't nearly as frequent as described in the article.)
Experimental brain surgery (Score:5, Interesting)
Apparently what happened in practice is that doctors would use coat hangers or any other bits of wire they could find, and slash at the brain until the symptoms stopped.
Arguably, though, severe brain damage (through cutting chunks out or prodding them wildly with steel rods) was probably a better fate than those in Victorian asylums, which combined all the home comforts of a Soviet-era Siberian prison camp with the theraputic properties of a medieval torture chamber. At least the victims of the medical experiments were often incapable of suffering much. (Some, just not as much.)
Modern therapies for brain disorders are often highly dangerous, extremely toxic to the rest of the body, notorious for side-effects, often addictive, and many are poorly studied with completely unknown long-term consequences. That is many thousands of times better again than those who underwent the surgery.
With the newer discoveries being produced through fMRI and other next-generation scanning equiptment, I fully expect the next thirty to fourty years to produce as many radical changes to neurological treatments as the past thirty to fourty have. It'll be interesting to see how things change.
Re:Experimental brain surgery (Score:4, Interesting)
Around that time, theory was a lot more advanced than practice.
Boy is that an understatement. There was also little in the area of medical ethics. A lot of those doctors should have gone to jail for what they did. This is the same era where insulin shock and electro-shock were standard practices for several mental illnesses. What a sick and sad time.
Re:Experimental brain surgery (Score:2, Informative)
Re:Shock Therapy (Score:5, Informative)
Your computer (like your body) may run fine for a while, it may even go to sleep and wake back up and go on running normally. Eventually you may come across some quirky behaviour (mental disorder) that you can't fix with patches (surgery?) or subsystem resets (drugs?). When all else fails, you reboot your computer (ECT) and everything goes back to normal.
ECT induces a seizure [wikipedia.org], and your brain sort of shuts down and resets itself. The mechanisms aren't entirely understood, but it works well to treat severe depression.
Electro-Shock Therapy has been portrayed as horrible torture (which it was used for) and has been tried for the treatment of many mental conditions (like schizophrenia and personality disorders) where it does little to no good. It definitely has a shady past, but the modern reality is much more benign and therapeutic.
Re:Experimental brain surgery (Score:3, Insightful)
--
Evan
Re:Experimental brain surgery (Score:3, Insightful)
Modern therapies for brain disorders are often highly dangerous, extremely toxic to the rest of the body, notorious for side-effects, often addictive, and many are poorly studied with completely unknown long-term consequences
And what do you base this comment on? Modern therapies are rarely dangerous (felbamate being the only modern therapy I would have said was dangerous and that is restricted), have few side effects especially compared to their action, aren't addictive, and are very intensively studied
Re:Experimental brain surgery (Score:2)
You must be new here.
Re:I never considered surgery (Score:2)
No neurosurgeon ever suggested surgery as a solution, but based on cases like this, I think I would have declined the offer had it been made. I can't imagine actually having part of my brain removed, and because everyone is different, results like this man's can never be 100% avoided.
The 1950s weren't exactly a proud time for neurology. The lobotomy only lost favor as a "treatment" in the 50s because of the advent of thorazine. The guy that invented the lobotomy actually won the nobel prize for medicine i
Re:I never considered surgery (Score:5, Insightful)
Complex partial seizures originating in the temporal lobe have one of the best success rates in epilepsy surgery, but surgery is only offered to patients whos epilepsy is medically refractive (cannot be controlled by drugs) and affects their life in such as way that they would strongly benefit from surgery. Temporal lobe epilepsy is most often caused by mesial temporal or hippocampal sclerosis, this means that that part of the brain has become scarred and shrunk and this damage is causing the seizures. So this part of the brain supports a minimal amount of function. As your seizures are probably well controlled by drugs, you would never have been offered a surgical option.
we still don't know enough about the way it works to reliably fix problems that the brain itself cannot handle.
That's correct to a certain extent, but we do know a lot more and one of them is how to avoid causing the sort of condition that HM suffers.
first dates (Score:4, Funny)
Re:first dates (Score:2)
I've read about this before (Score:5, Informative)
When my mother had a stroke... (Score:5, Interesting)
I rushed to the hospital, she seemed ok, but weak. We talked for hours, everything seemed fine. I still don't know what prompted me to ask the question as our converstation was pretty much normal. I asked her "Do you know you who I am?"
She said "No, should I?". Pretty much the worst moment of my life. As it turned out, she though it was 1968 and she was in there to give birth to what would be my brother Kevin.
Thankfully, over the next few weeks, most of it came back, but it all came back in chronological order.
She was back to the 1980's within a few hours, but the next 12 years came back much slower. She thought I was still with my first girlfriend circa 1990, that we had our old pets. The last few years were the only thing that remained somewhat little fuzzy.
I always thought that was very telling about the mind. Not sure exactly what it says, but it definitely says something. Maybe memory is stored tree-like. The other thing that was odd, was the closer to the present it got, the slower it came back.
Re:When my mother had a stroke... (Score:2)
While I'm not a cognitive scientist, I am thinking that could be because earlier memories have been remembered thousands of times, and reinforced all the more during each remembrance. Newer memories haven't had that reinforcement yet, and the neural connections will be weaker. Perhaps?
Re:When my mother had a stroke... (Score:3, Interesting)
Re:When my mother had a stroke... (Score:2)
--Ryvar
Re:When my mother had a stroke... (Score:5, Funny)
That's easily explained through general relitivity. As she travelled through time her "speed" in time increased, thus leading to a temporal dialation effect, slowing her down.
Re:When my mother had a stroke... (Score:3, Insightful)
Okay, the followup articles . . . (Score:2, Insightful)
This article [discoveryhealth.co.uk] talks about "In the 19th century a German anatomist Leopold Auerbach observed a complex network of nerve cells in the human digesti
Is there a name for what *I* have? (Score:5, Interesting)
I've have one that's very specific, but only been a minor nuisance. I blow people's names. Especially in a work environment, where I'm constantly meeting new people. A new person will have to remind me of their name anywhere from six to twelve times before it sinks in. Some people I know for awhile, then start calling them by the wrong name for a while. Then I stop that and get back to calling them by their right name again. Most people are understanding (I have to explain myself), but some get quite offended.
Mind you, it's the only memory defect I have. I can remember a face after meeting a person once and not seeing them for years. In conversation with a co-worker on a day-to-day basis, I can tell them what we talked about yesterday, what they were wearing last week, everything they've told me about themselves down to the most minute detail. Just not their name! But in most cases, I finally get them straight after a few months.
I was just wondering, with all the psych buffs in here...(PS it works this way online, too. I'm more likely to remember posters by their sig, or even just by their writing style, or on other forums by their icons...I'll even place people by their ID-number before their names!)
No it doesnt sound stupid (Score:2, Funny)
Re:Is there a name for what *I* have? (Score:3, Funny)
I can get away with calling everyone "mate".
Re:Is there a name for what *I* have? (Score:2)
Re:Is there a name for what *I* have? (Score:3, Insightful)
It takes a fairly major mind shift when you first mee
Re:Is there a name for what *I* have? (Score:2)
Re:Is there a name for what *I* have? (Score:5, Informative)
Curable/copable for most people using mnemonics. I can do a few people at a time now, by imagining them in a hug with someone else with the same name. I hold the pictures better than the words. Still can't cope in a new contract when I have ten people to remember: I won't be able to hold any of them.
Only works for first names, and only names I've come across before, so not a perfect solution!
Justin.
Re:Is there a name for what *I* have? (Score:2)
Re:Is there a name for what *I* have? (Score:3, Interesting)
Is "holding pictures" meant to be metaphorical in any way? Until recently I thought "I can see it in my mind" was just a flowery way of saying "I am familiar with it". I'm quite blind inside in most mundane states of consciousness - couldn't even visualize a circle, much less whatever happy places people purport to see in meditations. Yet I could probably describe or draw familiar faces or objects as well as or b
Re:Is there a name for what *I* have? (Score:3, Informative)
Shit, I just thought: how do you do, shall we say, relief?
Don't answer that, OK ;-)
Justin.
Re:Is there a name for what *I* have? (Score:3, Funny)
Re:Is there a name for what *I* have? (Score:2, Interesting)
No psych buff here but I remember reading that the association for names is stored in a different place, a more recent area that lives outside the hippocampus (primitive or early brain), probably because language skills came later on the evolution cycle. You can remember the aftershave/perfume they wear, mental image of their features and the way they walk, habits etc. because they are more closely linked to the hippocampus. Think early man and what he needed to know to survive, that's at the core and read
Re:Is there a name for what *I* have? (Score:2)
Interestingly enough my memory for just about everything else is very good.
I've mostly solved the problem by the simple expedient of calling everybody "You there"
Re:Is there a name for what *I* have? (Score:3, Insightful)
Re:Is there a name for what *I* have? (Score:3, Funny)
What do you call a three legged donkey ?
A wonky.
Nice: 43 Years Later Slashdot's Still got the edge (Score:3, Funny)
HJ
More importantly (Score:3, Interesting)
Re:More importantly (Score:3, Interesting)
Comment removed (Score:5, Interesting)
Re: (Score:3, Interesting)
Re: (Score:3, Interesting)
Re: (Score:3, Interesting)
Human Experiments (Score:2)
Hooray for progress!
Re:Human Experiments (Score:2)
Re:Human Experiments (Score:2)
Re:Human Experiments (Score:2)
The original operation involved cutting out large sections of this persions temporal lobes. I'm reasonably sure that this procedure would fall under the "experimental" heading as I doubt it would become an accepted practice once the results had been observed.
Re:Human Experiments (Score:2)
The original operation was a bilateral anterior temporal lobectomy. The patients subsequent anterograde amnesia was the result of both hippocampi being removed. Further tests, using anaesthetic not surgery, revealed that amnesia did not occur as long as one hippocampus could support memory function. Unilateral anterior temporal lobectomies were the result and are now the commonest surgical treatment for epilepsy and are very much accepted practice.
Textbook (Score:2)
This is fantastic (Score:5, Funny)
This is fantastic (Score:5, Funny)
Re:This is fantastic (Score:2)
Well of COURSE... (Score:2)
It seems obvious in hindsight that temporal lobes would be responsible for temporal mechanics.
Life imitates art.. (Score:2)
sort of common (Score:4, Informative)
I wonder (Score:3, Funny)