Cardiac Patch for a Broken Heart 147
Roland Piquepaille writes "People who suffered from heart attacks or other heart failures often need transplants because their hearts are essentially non-functioning. But imagine what would happen if it was possible to engineer living heart tissues to fix these broken hearts? This is what bioengineers at Columbia University Medical Center in New York City are starting to make. According to HealthDay News, their patches for broken hearts are made of heart tissue grown in the lab. Right now, animal trials are just starting and it will take at least a decade before human trials begin. But when these living bandages are ready for cardiac care, they'll have the potential to save millions of lives in the world every year."
My patch (Score:4, Funny)
Re:My patch (Score:1, Funny)
Re:My patch (Score:2)
You saw this coming Re:My patch (Score:3, Funny)
Patching is for paranoids, I'd rather check out the bleeding edge release.
Re:My patch (Score:1)
That's a really surreal image there. Salvador Dali eat your...
No, wait...
But will this work... (Score:5, Funny)
No? Then forget it. Back to alcohol and chocolate for me.
Re:But will this work... (Score:2)
If it's anything like a MS Windows patch... (Score:5, Funny)
Re:If it's anything like a MS Windows patch... (Score:1)
Har harr harr heee heee heee giggle giggle *slapping knee* giggle snort.
Ooo! Tell us the one about the MS car that always crashes!
Re:If it's anything like a MS Windows patch... (Score:2)
Re:If it's anything like a MS Windows patch... (Score:1)
Not at all. I laughed at that joke the first time I heard it back in 1999.
Will they schedule them for tuesdays? (Score:1, Funny)
Stem cell source (Score:1, Informative)
Whether everyone else agrees or not, Catholics have strong objections to abortions and, thus, to any product derived from the tissues of aborted children. Thus there is a demand, froma Catholic perspective, and a refusal, from an anticatholic perspective, to differentiate cells derived from aborted babies.
on vaccines from aborted babies:
http://www.geocit [geocities.com]
Re:Stem cell source (Score:2)
Quit bringing that stemcell debate crap into every medical advance that's out there please.
Re:Stem cell source (Score:2)
It could only be with people believing in eternal damnation that a virus that was isolated and attenuated decades ago with the help of celllines from aborted fetuses that the vi
Re:Stem cell source (Score:2)
You are actually getting it. What's happening is that only religious societies tend to be male dominated enough to reproduce for the expansion of its population. Liberal areligious European society is dying out, as is liberal America. Evolution wins. Irony of Irony, Darwin loves God best.
Re:Stem cell source (Score:2)
Would a Catholic go for a cadever bone transplant or something else?
While I appreciate the expressions of the Pope regarding this issue, is it really morally any different than a White Supremacist who refuses a blood transfusion from a nigger or kike, with the same level and depth of moral convictions and feelings? After all, if we're to take the Catholic Church with respect, should we not also grant the
It's old, but I like it (Score:1)
He heard that boy's pants were half off.
Re:It's old, but I like it (Score:2)
Unluckily (Score:5, Funny)
Re:Unluckily (Score:1)
Not even an achy breaky one?
Very interesting, but why just for cardiac tissue? (Score:5, Interesting)
I'm also wondering if it was possible to use cancer research to produce an anti-cancer... No I do not mean a cancer cure, but an infection of healthy living tissue. Is it possible to introduce healthy tissue into a body or system and have it spread in a cancer like fashion repairing everything in its path? That would be way too cool!
--Matt Wong
http://www.themindofmatthew.com [themindofmatthew.com]
Re:Very interesting, but why just for cardiac tiss (Score:1)
Re:Very interesting, but why just for cardiac tiss (Score:2)
Problem is, that's kind of what tumors already are -- normal tissues without the normal restriction on growth. (Yes, I realize that's a huge oversimplification. You don't need to explain why.) Almost by definition you can't beat cancer by adding new tissue to outcompete it.
Re:Very interesting, but why just for cardiac tiss (Score:3, Interesting)
As others pointed out, planting "healthy" tissue that outgrows cancer is just giving someone a worse cancer.
Re:Very interesting, but why just for cardiac tiss (Score:2)
My personal suspicion is that the people they try this on will generally shortly die of strokes, or it will work. When an unusual heart treatment doesn't work it usually causes strokes.
Dick Cheney (Score:5, Funny)
Re:Dick Cheney (Score:3, Funny)
Re:Dick Cheney (Score:1, Funny)
Re:Dick Cheney (Score:1)
no you don't. you posted as AC, pantie waist.
Re:Dick Cheney (Score:2)
It's a joke about Cheney not having a heart in the figurative sense. Look up the word heartless [reference.com].
Re:Dick Cheney (Score:1)
I'm afraid you're gonna have to ask the Wonderful Wizard of Oz for that...
Besides, if he can't do it, no one can
Re:Dick Cheney (Score:1)
"I need a new heart." Says Cheney. Poof, the wizard grants him a heart as healthy as a 20 year old.
"I think I need a new bike..." Bush says, as the others elbow him in the ribs. "I mean brain." Poof. The Wizard gives him the brain of a genius.
Clinton then approaches the Wizard, looks around and says. "So, uhm, where's Dorothy?"
Re:Dick Cheney (Score:1)
Ouch. Be careful with GWB jokes, they can really backfire!
I could have sworn... (Score:4, Funny)
Tissue Engineering isn't just for hearts either. (Score:5, Interesting)
I'm excited about this growth area in medicine - not as a doctor or as a medical professional (sorry I am squeamish at blood) - but as a parent of a child who stands to benefit enormously from this kind of research. I hope and pray that this kind of stuff - patching hearts, augmenting bladders, mending broken organs in general - all develops and gets to the point of viability in time.
Mark.
Re:Tissue Engineering isn't just for hearts either (Score:2)
Re:Tissue Engineering isn't just for hearts either (Score:2)
Re:Tissue Engineering isn't just for hearts either (Score:2)
Why not stop the root causes? (Score:1, Interesting)
Start a fat and salt tax. If you serve more than 100 customers a day and your food is unhealthy charge the expected cost in healthcare that triple cheeseburger is going to cost in 30 years when that customer is ju
Re: (Score:1)
Re:Why not stop the root causes? (Score:1)
I hear that loud and clear. Too bad it's going to run out in about 40 or some years from now regardless. (Or so they say) So I say that if you've got a qualifying disability, then you may just as well get your money back while you can. Don't wait for it to not get fixed. ;)
Re:Why not stop the root causes? (Score:1)
If you don't think the tobbaco companies are proactive in creating new customers (kids and teenagers) you are delusional. Especially chec
Re:Why not stop the root causes? (Score:1)
Re: (Score:1, Offtopic)
Re:Why not stop the root causes? (Score:1)
And I never said that they shouldn't be allowed to be among other people. A restaurant is private property. A sidewalk in the city generally isn't. A government building isn't. If the person or business that owns property wants to allow smoking in it, they should be able to.
Re:Why not stop the root causes? (Score:1)
No, it's not easy. I can vouch for that. It took me about four or five times to quit myself. A lot of it's I think 'in your head' and how you cope with things, stress, and so forth. I know it's damn near impossible to quit if you're not too happy with your life as it is. But, it does get a bit easier to quit when you take yourself out of bad situations and get yourself a better outlook. Then, all you really have to deal
Re: (Score:2)
Re:Why not stop the root causes? (Score:1)
I believe you about the routines, as that was part of my problem, too. For me, it was either after dinner, after just stepping outside, after getting nagged at by the ol' ball and chain, being in the bar amongst other smokers, and other situations like that. A lot of things would trigger me to light up,
Views of a communist (Score:1)
Firstly with such a law passed, this decreases "freedom". With smoking out of the picture in public places eventually more things will become illegal and with time this world will turn into a dystopia, where
Re:Why not stop the root causes? (Score:1)
As for small town living, ymmv but for me it's alright.
Re:Why not stop the root causes? (Score:2)
Hey, city slicker, stop passing laws (and the taxes to pay for them!) in the legislature to make the rest of us rural folk pay for your increased infrastructure requirements, crime problems, etc.
Hey, LA, got an earthquake problem? Well, silly you for living in an earthquake zone.
In the end,
Re:Why not stop the root causes? (Score:1)
Try it in your own country... (Score:1, Offtopic)
Because
1) it just won't be there for them anyway, and
2) people then expect to be taken care of.
That in no way encourages responsibility.
Re:Try it in your own country... (Score:2, Interesting)
Re:Try it in your own country... (Score:2)
I'm sick of people telling me i shouldn't smoke and then getting offended when i say and you shouldn't be eating that pie fattie.
I don't normally eat pie... I am not a fan of desert in general, most of the time... But when I eat desert I try to keep the food to myself. I try to keep my food out of other people's mouths and off of their clothing. If you decide not to have any cake at a birthday party do you and your clothes end up smelling like chocolate cake when you get home?
Personally, I don't c
Re:Why not stop the root causes? (Score:1)
I think that the other shoe is finally dropping here. Minimalls seem like a great idea, but they aren't exactly nice to look at and contribute a lot to people getting in their car to drive two minutes instead of either walking the whole way or driving to one or two key locations and walking from there. And I think city planners are
Re:Why not stop the root causes? (Score:2, Insightful)
If people would walk, bike, run, or skate to their destinations more often we would have less of an obesity problem also. Moderation in everything, including moderation.
Cities DO have areas which are not polluted by car exhaust and other harmful things. Have you ever been to Manhattan? There's a sm
Public Health costs (Score:4, Interesting)
I know there are a lot of people who live a good life & then suffer heart failure, but there is also a lot of people simply who simply live badly, they drink and smoke too much, eat too much & they don't exercise.
If there was a quick fix to heart problems, how many people would change their lives? Would they improve their quality of living or would they simply just resume their old ways & end up having to have the procedure again at the expense of the public health system.
Im all for ways of improving our chance of living through medicine, but there are a lot of people who bring upon these conditions because of their own lazyness & over-indulgence. Fixing their hearts won't nessesarily make them want to improve other area's of their life which created the heart problem in the beginning.
With medicine getting better & much more serious conditions being able to be fixed a lot easier, what are the social implications of this, humans are lazy, would it help create a society of people less concerned about their health? And what would that cost?
Re:Public Health costs (Score:3, Insightful)
Re:Public Health costs (Score:2)
You know, you can say that about a lot of diseases. You get lung cancer from smoking. You get liver problems from drinking. People primarily [1] get HIV through doing stupid things that are universally known to be stupid. But yet, we do what we can to
Re:Public Health costs (Score:2)
Well, when society can't bear the cost any longer, the problem will take care of itself... And if this never happens, then there isn't a problem.
Re:Public Health costs (Score:2)
I suggest you read this mostly true story about a drug rep in comic form. [ministry-of-fun.com]
I bet if they stop covering Viagra and buying $20 gallons of orange juice, insurance companies can recover the costs of the occasional extra open heart surgery.
Re:Public Health costs (Score:2)
Damn, what I meant to say is:
I'd bet if insurance companies stopped covering Viagra and pharmacutical companies stopped buying $20 gallons of orange juice, we could recover the costs of a few extra open heart surgeries.
Re:Public Health costs (Score:2)
What happens when the Baby Boomers hit 90 and we get genetic medicine right at the same time, extending their lives to 120.
How's Social Security going to hold up?
Re: (Score:2, Funny)
Because of the AMA, don't hold your breath... (Score:2, Informative)
My daughter was born eleven years ago needing a heart transplant. The four pediatric cardiologists in this state all argued over which of several procedures would be best, but in the end none of them would do a damn thing to help her because the AMA recommended against all of the procedures except a transplant. Legally the doctors could help her, but they were too afraid of the AMA. In the end, we had to do a transplant. That cost $225,000 for just the
Re:Because of the AMA, don't hold your breath... (Score:1)
For female patients (Score:2, Funny)
The male patch will consist of pornography and alcohol.
True Story (Score:5, Interesting)
However, the pump mashes up the blood cells and was giving him anemia.
Soooo... They pulled it out and stuck in a new one. This artificial heart has a turbine in it to push the blood along. He no longer has a pulse, just a blood pressure.
Re:True Story (Score:2)
So he's a Time Lord, then?
(Sounds a bit like my grandmother, who after three hip replacements has difficulty walking, but waltzes divinely)
Re:True Story (Score:1)
wow... (Score:3, Funny)
Re:wow... (Score:2, Funny)
No, the cat does not "got my tongue." (Score:1, Troll)
> take at least a decade before human trials begin. But
> when these living bandages are ready for cardiac care,
> they'll have the potential to save millions of lives
> in the world every year.
While I can see engineering taking awhile to develop something useful to humans, keep in mind that every year delayed "proving it" to arrogant government officials kills millions a year. Now explain to me why exactly they are a friend to humanity ag
Re:No, the cat does not "got my tongue." (Score:2)
You don't catch the non-nerd news much, do you? Even drugs that are tested a lot, but which have some mixed results, end up being not perfect for at least a few people, someone (who is already very sick in some other way) ends up dying while using the prod
Much More Complex Than Growing Meat (Score:3, Interesting)
Growing heart tissue would be much more demanding requring "exercising" the muscle, plus as the article pointed out there are problems of tissue acceptance, adhesion and syncing the pulse of the muscle patch to the existing heart tissue. Given these hurtles it looks like this technology has many hurtles to jump.
Pursuing an interest in Dictyostelium amoebae [dictybase.org] provides an starting point to studying chemotaxis and cellular communication.
For the Bee Gees (Score:2)
try.. (Score:2, Funny)
Hole in the heart (Score:1)
My brother like most people with down syndrome was born with a hole in his heart, the doctors used some wierd material to patch it, they seemed quite good at it scince the doctor had also done a girl born with down syndrome a few hours earlier.
Re:Hole in the heart (Score:2)
In heart attacks a portion of the muscle dies (ironically, because of impeded blood flow) and cannot be repaired using current techniques since it would involve wholesale replacement of the affected region to restore full function.
By way of analogy: a steel plate will fix a
Exciting! Holy cow, I want this! (Score:5, Interesting)
The real question is, could they grow a proper heart or replacement pieces from my genes at all? I had six major life-threatening heart defects that were mostly corrected, but there's always that lingering feeling that things could be better. If not for the surgery, I'm sure I'd be dead by now. Hell, I almost didn't make it past two months. Would something like this work for me? Would it be worth going back in there to complete the repairs?
Who knows. But I have to say this is definitely a thought-provoking piece of information. Unlike people who undergo heart-surgery in their later years, I never had a fully functional heart. Ah, the possibilities!
For those keeping score, this should sate your curiosity:
1. Faulty aortal valve: mostly corrected, slight murmur remains
2. Transposed position (It leans right instead of left): uncorrected
3. Half expected size: repairs later encouraged growth
4. Unknown muscle-tissue grown over heart: removed
5. Large hole between ventricles: covered with Dacron patch
6. Two small holes between atria: sewn shut
I'm holding out for... (Score:2)
Finally! (Score:2)
(Seriously... this is great news. I hope it works.)
Re:Finally! (Score:2)
Great news! Another double Quarter-Pounder, please (Score:2, Funny)
A few issues to address still (Score:2)
1. Proper muscle function. If the cardiac patch grows and replaces the dead tissue, it will not do much good if the muscle doesn't contract and pump blood like real tissue does.
2. Scarring. The heart would have a large amount of scarring from where the ischemic tissue was removed. Also, the graft would n
Re:A few issues to address still (Score:2)
Yeah, it could have gone badly, but it would have been far worse if I didn't get the surg
Every ten years is actually only seven and a half (Score:1)
Not as impressive as the doubling of chip speeds, but when you think about it, the average person born today is going to live about 20 years longer than the people that
Already growing new hearts, limbs, in mice (Score:1)
Re:Already growing new hearts, limbs, in mice (Score:1)
Better solution: (Score:1)
But what kind of patches are they? (Score:2)
Great idea, until.... (Score:2)
I have a friend who moved to Canada last year, and he has been telling me stories about the health system up there. Basically health coverage is provided by the government at no charge to the patient. I don't know all of the details, but he told me he was in an
What do YOU want to die of? (Score:2)
heart valve repair (Score:2)
Makes you want to live near a hospital. See? City living is healthier after all!
That's what we're doing (Score:3, Insightful)
Natural selection, we are enabling our species to maximize its population and survive regardless of obstacles. That way we can benefit from intellectual contributions of everyone (even those who may have a physical problem). Plus, we also want any good genes the person may have (for example, maybe the person has a bad heart, but maybe they also have an awesome improved kidney gene).
In a couple generations we may be able to do gene therapy and eliminate any detrimental genes.
So yes,
Re:Why fucking bother? (Score:1)
Re:Why fucking bother? (Score:1)
Re:Die Roland Piquepaille, Die (Score:1, Offtopic)