Extremely Accurate Nanotech Cancer Test Developed 128
Sylvestre writes "Medical News Today reports that Harvard researchers have developed an accurate test for cancer using nanotechnology. From the article: 'Harvard University researchers have found that molecular markers indicating the presence of cancer in the body are readily detected in blood scanned by special arrays of silicon nanowires -- even when these cancer markers constitute only one hundred-billionth of the protein present in a drop of blood. In addition to this exceptional accuracy and sensitivity, the minuscule devices also promise to pinpoint the exact type of cancer present with a speed not currently available to clinicians.'"
Re: (Score:3, Informative)
Re:Is this technology carcinogenic? (Score:2)
Re: (Score:2)
Re:Is this technology carcinogenic? (Score:2)
Re: (Score:2)
Re:Is this technology carcinogenic? (Score:4, Insightful)
Indeed, and yet one can't help but wonder if this wouldn't be integrable to nanochips implanted in one's body to check one's body's evolution in real time.
Some cancers are hard to detect and evolve extremely fast, once the first symptoms show themselves is already too late for the man to have any chance of survival. Having the ability to track cancer's birth and evolution in real time would prove extremely valuable to both patients and medical organisms...
Re:Is this technology carcinogenic? (Score:1)
Re:Is this technology carcinogenic? (Score:2)
intresting but... (Score:1)
RTFA (Score:5, Informative)
"A nanowire array can test a mere pinprick of blood in just minutes, providing a nearly instantaneous scan for many different cancer markers."
Re:GAFC (Score:1)
Re:GAFC (Score:1)
BTW, in English, sentences usually begin with a capital letter.
Over the counter? (Score:5, Interesting)
We're already a society of hypochondriacs. Imagine if you could test yourself at home for every devestating disease there is.
Of course, I'm getting a ahead of myself. Early detection is the best defense. If this is as good as they say it is, it could save a LOT of lives.
Re:Over the counter? (Score:4, Funny)
Re:Over the counter? (Score:2, Informative)
"Well, maybe I administered the test wrong...I'll just go back to the store and get a few more so I can try again...then I'll call my doctor..."
Re:Over the counter? (Score:1)
That is how my gf and I felt when she took some pregnancy tests after missing her period. After two of the three in the box said NO, we wondered, "Hmm. Maybe this was a bad batch and we should go back and buy another brand?".
No, we didn't do it, but it was difficult not to and to just trust that the test was accurate.
Re:Over the counter? (Score:1)
Re:Over the counter? (Score:1)
Re:Over the counter? (Score:2)
Of course, it's not likely to be over the counter for a long time, given that they're going to be disposable 'chips' that are plugged into a multi-thousand dollar machine to interprit the results. Each chip will be cheap*, so it'll be part of your annual physical, and allow faster cancer diagnosis, as well as for other diseases.
*In medical terms
Re:Over the counter? (Score:5, Insightful)
Re:Over the counter? (Score:2, Insightful)
Re:Over the counter? (Score:2, Informative)
"Assuming individuals test themselves regularly (every 6 months perhaps)."
This is exactly the issue, if people test themselves. I was diagnosed with Accute Lymphoblastic Lukaemia (ALL) in Jan 2003, I hold the record for the highest circulating Lukaemic count in an adult in Queensland(Australia) - I could have been diagnosed sooner had I been tested, the issue is that I didn't think I needed to see a doctor for testing. While tests like this are excelent in providing difinitive results for early detection i
Re:Over the counter? (Score:5, Interesting)
That said, if these tests were really that accurate and could be done at home, that might help. People who are hypochondriacs could test their blood and find out they DON'T have cancer. After using such a definitive test a couple of times they might very well "get the picture" that their next headache is a headache and not a brain tumor.
On the other hand, if these things are sold to the public and have much of a false positive rate, that would be a BIG problem.
Re:Over the counter? (Score:2)
Re:Over the counter? (Score:3, Insightful)
Well, apendicitis and cancer are hardly "insanely rare disorders". Uncommon compared to cramps or flu maybe, but common enough for most people to have family members or friends suffer from them.
Re:Over the counter? (Score:2)
Re:Over the counter? (Score:2)
Right, but you do get people like me going into the ER at 23 years old thinking they have had a heart attack, when come to find out it's just heartburn due to pizza consumption.
I was laying on the couch, when my chest started hurting; so I go upstairs to check the interwebs to see if I did have the symptoms of a heart attack. Lo and behold, I had chest pains, tingling in my arm, and lightheadedness!
Turns out it was just due to the aforementioned pizza, the fact that I was laying on my arm, and the fact tha
Hypochondria, Internet, and the British Library (Score:3, Funny)
"It is a most extraordinary thing, but I never read a patent medicine advertis
Re:Hypochondria, Internet, and the British Library (Score:2)
Re:Over the counter? (Score:2)
Or if our little hypochondriac friend is financially well off enough we might find him or her taking one or more test per day so they'll always be sure
Comment removed (Score:4, Interesting)
Re:Over the counter? (Score:2)
Re:Over the counter? (Score:1)
A nanotech cure can't be far behind (Score:4, Insightful)
Re:A nanotech cure can't be far behind (Score:1)
How could you control their reproduction so that they don't clog your veins or saturate your organs?
Re:A nanotech cure can't be far behind (Score:2)
My advice would be to put the sci-fi book down and realize that nanotech does not equal grey goo of death. Nanotech could be as simple as slapping some RNA together into a form that pentrates only cancer cells and turns off their reproduction. It could be functionalizaing a carbon nanotube to pentrate only cancern cells and then heating them up a little and causing the cell to explode. Nanotechnology is
Re:A nanotech cure can't be far behind (Score:3, Funny)
Re:A nanotech cure can't be far behind (Score:1)
Thank you. (Score:3, Funny)
Re:A nanotech cure can't be far behind (Score:2)
for (i_be_nanite){
nanites++;
}
if (nanites 6){
die();
}
Re:A nanotech cure can't be far behind (Score:2)
Re:A nanotech cure can't be far behind (Score:2)
Other useful HTML entities here [cookwood.com]
Re:A nanotech cure can't be far behind (Score:2)
Designing a device that can detect chemical traces, seek out the source of those traces and destroy it - rather a bit difficult.
This is not, in my opinion a prequel to some sort of hunter/killer medical nanotech. It is, however, a HUGE step towards "curing" cancer: The survival rate for most cancers is much greater with early detection - this would allow MUCH earlier detection than we currently have - it could be part of a routine check-up
Re:A nanotech cure can't be far behind (Score:1)
Other uses? (Score:5, Interesting)
Re:Other uses? (Score:1, Troll)
Re:Other uses? (Score:2)
I know -- I already avoid beef.
However, I cannot donate blood in the US because, 14 years ago, I spent 4 months in England. If this test can be used to eliminate any question that I have these prions, there would be no need to "indefinitely" defer me.
Re:Other uses? (Score:1)
Re:Other uses? (Score:4, Funny)
Wonder if they can adapt this to be an accurate test for prion related disease like BSE (mad cow disiease). If it could be used for both humans AND other animals, the food supply could become safer.
Personally, I have no plans to eat humans, whether they have BSE or not ;)
Re:Other uses? (Score:2)
Re:Other uses? (Score:3, Insightful)
This is because the most "effective" infection vector (or whatever the term is) is for an infected (dead) cow to be fed to a healthy cow.
(And yes, this is common feeding practive.)
Eliminate animal cannibalism and much of the danger of BSE is eliminated; this should of course be accompanied by specific testing, but it's important to prevent outbreaks from becoming ep
Re:Other uses? (Score:3)
Source?
I don't know of any countries that still permit this.
-a
Re:Other uses? (Score:2)
On the other hand, it may help prevent people from consuming BSE-positive beef. I doubt that any ethical issues involved in testing will apply to livestock.
Comment removed (Score:3, Funny)
This is COOL technology (Score:5, Insightful)
Of course it is funded by DARPA, the army would love to have medical advancements like that on the battlefield. When a necklace every soldier wears instantly tells the med-tech that the wound the wearer is suffering has punctured a lung or spleen or something like that.
I can also envision this kind of technology being incorporated in care-giving robots for the elderly and infirm. If you have a 'tri-corder' like medical diagnosis kit that can fit on a robot, the robot then would know what to tell the 911 operator when it called, other than "help, they've fallen and can't get up" and that makes this type of nanotech VERY cool. Talk about search and rescue... a robot finds bodies in the rubble, slaps a triage-analysis bandage on their skin and can then tell rescue workers what kind of medical treatments are necessary.... Well, I hope that is what comes of this stuff. That magic little microphone looking thing that Dr McCoy always waved around was damned cool!!
I suppose one of the real drawbacks is that drug screenings for employment might be used to cancel insurance and work contracts etc. based on ineligiblity due to pre-existing conditions and bad things like that. (uhhhh thinking of bad scifi movies now)
Still, its cool.
Re:This is COOL technology (Score:3, Funny)
How much? (Score:3, Interesting)
Re:How much? (Score:2)
Re:How much? (Score:3, Insightful)
A few nanometers of silicon doesn't sound very expensive to me!
Kidding aside, let's not jump to assumptions. I'm sure with will be costly right at first, but what makes you think it's inherently expensive? You have to compare with the alternatives; it might well be cheaper than whatever they're doing now. And with the ability to diagnose cancer so much earlier and more accurately, the long-term treatment might well be much cheaper - oh,
Re:How much? (Score:2)
Re:How much? (Score:2)
Re:How much? (Score:1)
In fact, regardless of what it actually costs to produce I would imagine it will be "insanely expensive" until the patent expires.
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It's essential to consider the economic effects. (Score:2)
Re:How much? (Score:1)
Advances in technology are great, but only insofar as they are usable. How many people do you know of who get routine PET scans at a few grand per imaging session? What makes you think th
Re:How much? (Score:2)
The quicker you can catch it, the easier(and cheaper) it is to treat.
Early detection could substantially reduce the billions of dollars spent on cancer treatment each year. Not only does cancer screening save lives by detecting breast, cervical, and colorectal cancers early; it also is the first step in preventing many cases of colorectal and cervical cancers from ever developing:
Sensitivity & Specificity (Score:5, Insightful)
Re:Sensitivity & Specificity (Score:2)
While the microcancer issue is probably realistic, it would be spotted by the screening tests before the technology goes live.
As for the healthcare costs, cure and pain relieving of cancer cost a damn lot last time I checked, earlier simpler fully generic (read: mass-produced) diagnose tests and a fraction of the previous cures cost (since cancers would be barely born when spotted, years-long cures would more than likely become rarity more than common case) would probably drive the healthcare cost down, no
fear not. (Score:1)
Then you will know, what's to be afraid of? The incidence will be catalogued and fed back into treatment. So relax, the doctor does not know everything but he does the best with what he's got and has statistics to back it all up. Cancer treatment, where some forms have five year surviva
Re:Sensitivity & Specificity (Score:3, Informative)
Go look up 'lead time bias' and breast cancer treatments. The biggest shock is that we're now detecting far more breast cancers than ever before, yet the death rate (or 5-year survival) has barely changed.
This raises a couple of possibilities:
1 - We're just detecting cancers earlier, and our current treatments do nothing for those with the disease. I.e. people are living longer with the cancer not because the treatment is better but because they're diagnosed earlier.
2 - We're still failing
Re:Sensitivity & Specificity (Score:1)
"I fear this test will pick-up "cancers" of questionable significance."
My questions would be more about what types of cancer can be detected, I know there are dozens of forms of Lukaemia alone - not to mention "medical" cancers (Lukeamia being a haematological cancer). Is this kit capable of detecting liquid tumors aswell as solid tumors?
"What impact will such a test have on healthcare costs, if a battery of additional diagnostic tests are used to work-up a "positive" screening test?
Without the develop
Nano this, nano that (Score:3, Funny)
Screening semen samples for genetic abnormalities. (Score:1, Redundant)
Re:Screening semen samples for genetic abnormaliti (Score:3, Funny)
Welcome to Gattaca.
Concern: (Score:3, Insightful)
(Going on the theory that your body will always have a few cancerous cells - or at least some molecular mimicry of cancer markers - which the body's immune system can deal with so that tumors never develop.)
Re:Concern: (Score:2)
It's not like they're going to find a couple dozen lng cancer cells and rush you into chemotherapy or cut you open. This will give doctors more time to re-assess (and re-test) and track the cancer while working out possible treatments. I'd rather have a false positive than finding out I have cancer at the point when it's already a terminal situation.
Cool, but useful? Not so sure... (Score:5, Interesting)
However, using this as a method of detecting cancer might not be so useful. The presence of various markers in the blood is probably normal. What you want to know, is whether or not these markers are present on cells when they should be absent. They claim to be able to detect PICOgrams/mL of a specific protein in the blood. Unfortunately, all males have PSA in their blood and it's the amount that's important, not its presence. That's just for prostate cancer. Unfortunately, the sad reality is that we don't know enough about most cancers for us to know what to detect to be useful.
I can definitely see this as a useful tool for detecting hazardous chemicals and biologicals agents and scientists are always looking for more sensitive instruments. I think that's why the article appeared in Nature Biotechnology and not Nature. Still way impressive, though.
Re:Cool, but useful? Not so sure... (Score:2)
If we could detect those cells or other cells influenced by their passing we could find the cancer and irradicate it (Perhaps through microwaves?)
Re:Cool, but useful? Not so sure... (Score:1, Funny)
Thanks to this new test we will be able to detect *and* eradicate cancer without leaving the kitchen!
P.S. Is it ok to assume that "irradicate" means "eradicate by irradiation"?
Re:Cool, but useful? Not so sure... (Score:1)
Re:Cool, but useful? Not so sure... (Score:1)
Microfluidics, the type of technology involved here, doesn't just measure the types of things encountered in the blood stream, it can also mea
Well.. (Score:2, Insightful)
Re:Well.. (Score:2)
Re:Well.. (Score:2)
And as another poster pointed out the test should be cheaper. Most of us would have better preventative medicine if it wasn't for the cost factor. If getting this done is cheap enough it would be something that someone could do in their recommended check ups.
On a semi-related note, how long does it normally take from the onset of most cancers to the point where the patient would be aware of "something going wrong"?
Re:Well.. (Score:2)
almost all cancers that are detected via prevention techniques such as colonoscopies, mamograms, etc are caught with enough time to do something constructive, but by that time it is still farther along than one would like. if you can detect a cancer that has just formed, or is very very small and has not had time to infiltrate other tissues around it, it is very easy to remove and cure. This tech should allow t
But screening would help with that (Score:2)
Which is why for common forms like breast cancer, there is a screening programme for those most likely to be at risk. The killer about cancer -- quite literally -- is usually finding it too late. The survival rates with sufficiently early diagnosis are very good for most forms of cancer today, even those that sadly remain mostly lethal by the time they are detected using obvious physical symptoms.
A reliable and readily administered detection mechanism for even most forms of cancer would probably save many
sounds expensive (Score:1)
Nano Overload... (Score:4, Funny)
Battlestar Galactica (Score:1)
Sure, but at what cost? (Score:2, Funny)
Without this test, rich and poor will have a more equal chance of dieing of undiagnosed cancers. Therefore, they shouldn't have developed this test.
My leftist friends told me inequality is bad.
This isnt new at all... (Score:1)
Sounds like the main improvement is cost (Score:4, Insightful)
You are missing the point (Score:1)
Re:You are missing the point (Score:2)
Patented? (Score:2)
So that means not patented?????
Danger Will Robinson! (Score:1)
Of course, then this person really does get Cancer and sues the doctors for it.
Side effects: (Score:2)
So we all have cancer now? (Score:3, Interesting)
Will this extremely accurate test be able to tell between unchecked cancer cells and those few cells which the body would take care off naturally? Or are we all going to turn into cancer patients ?