Scientists Creating Life From Scratch 355
Rubberbando writes "MSNBC is running a story about bioengineering organisms to do specific tasks such as produce hydrogen or ethenol. It also goes into the risks and ethical issues of playing with this sort of science. Some of the scientists involved are saying it's more of an art instead of a science due to its 'biohacking' style of experimentation."
Becoming a god (Score:3, Insightful)
the intelligent design (ID) is just another horse crap
made up by humans. The base of ID's claim lies on the belief
that the design of some rudimentary living organisms are
just too complex to be built by accident. Hence
some higher intelligence -- beyond human intelligence --
must be involved in creating such organisms. But now, we
are stepping closer to make one on our own. What does that
say about humans? Are we becoming a god?
No. It's all about perception. From our point of view, some
things may look too complex to be formed accidentally. But
as science advances, our perception does evolve (or should).
If our society continues to exist (not sure if that happens
in Kansas or in Bill Frist's home, but let's not go there),
then what it seems an impossible task may not be so impossible
any more.
Well, that's my opinion and I'm sticking to it.
Re:Becoming a god (Score:5, Funny)
Good for you! That's following the scientific method! Keep that mind closed up tight! ;)
Re:Becoming a god (Score:3, Insightful)
I'm not saying anything for or against ID, but if they claim it couldn't happen by accident, then humans doing it on purpose doesn't really disclaim that.
-1 Faulty logic.
Re:Becoming a god (Score:4, Insightful)
The fallacy in your statement is in the fact that these organisms weren't merely created by accident - they were intelligently created by scientists in a lab. So the fact that this occurred only reinforces the supposition that it could not, in fact, happen on accident. As far as the supernatural beings requirement, manufacturing simple organisms is one thing, but we are still infinitely far off from being able to manufacture another human (at least without a few beers and some luther vandross). Put simply: they just proved intelligent design could occur.
Re:Becoming a god (Score:5, Insightful)
If anything, this solidifies intelligent design's viability as an alternate theory. After all, this new life was INTELLIGENTLY DESIGNED!
Re:Becoming a god (Score:2)
Also, these organisms were created over the last 30 years of human knowledge. The rest of the world had billions of years to arrive where we are now.
I won't hazard a discussion about where all life came from but the two competing theories in my mind don't compete. In reality evolution doesn't explain where it all began, only how we arrived where we are today. Picture it like traveling
Re:Becoming a god (Score:2)
That's a little like drawing a circle around a can of beer and then claiming that all circles that occur in nature were drawn around beer cans.
Re:Becoming a god (Score:5, Insightful)
The true test of creating new life "from scratch" is still not even close to coming to frutition.
But don't let that stand in the way of a good rant. We all love a good rant.
Re:Becoming a god (Score:4, Insightful)
See, by your logic, this proves that intelligence can brew life from no life...thereby supporting ID.
Tangent: Personally, I've never understood why science and religion must be at odds. Why can't one's deity be the one who caused these scientific laws and phenomena, and either nudged evolution a little bit here and there or maybe just planned it all in the beginning (like writing a program, or planning a chess game ahead) and set it loose?
Re:Becoming a god (Score:3, Funny)
Re:Becoming a god (Score:2)
Re:Becoming a god (Score:2)
But the thought behind WHAT to splice, mutate, and ligate is very different. They use engineering and mathematics to _predict_ what will work _before_ they build it.
So it's not the trial and error prone protocol of traditional molecular biology. It's more like real engineering.
(Or, what, did you think they create a million different skyscrapers and the one which stays up is copied?)
Re:Becoming a god (Score:2)
I appreciate that they are putting thought into this, but the article didn't actually go into any of the METHODS used for actually splicing the DNA sequence. All the ones that I know about are basically A)splice it into a retrovirus, infect the host with a vi
Re:Becoming a god (Score:3, Interesting)
Science helps us understand how God did it. I believe God will never break a law of the Universe. Why should He?
Re:Becoming a god (Score:2)
I don't think Intelligent Design necessarily states it has to be an intelligence beyond humans. It states that natural processes is insufficient to explain the development of organisms, therefore some sort of intelligent manipulation was involved. I don't see how intelligent manipulation
Re:Becoming a god (Score:2)
>It's all about perception. From our point of view, some things may look too complex to be formed accidentally.
And having an intelligent being (a human scientist) create life is evidence in favor of evolution over intelligent design how? If anything it will encourage the creationist (excuse me, intelligent design) camp more.
Not that I believe their nonsense. That life can be created from scratch by intelligece doesn't mean that our life was created that way. B
Re:Becoming a god (Score:3, Insightful)
Man invented God, not the other way round. That's intelligent design.
Re: (Score:3, Funny)
Re:Becoming a god (Score:2, Interesting)
Well, because we have hands and whatnot, as opposed to imaginary magical, worshipper-fueled, fantasy Santa-Clause-like mythological constructions that are easier to dream up than complex biology is for a lot of people to understand. Pretty much that's why. I think it's a lot like wondering why the breakfast you're eating, as just made by your mom, isn't an indication (or proof, even) that the Easter Bunny could also have made breakfast.
Re:Becoming a god (Score:3, Insightful)
The suggestion that some theoretical higher being could create life was never in dispute. What is in dispute is whether the higher being exists.
Showing that humans can create life demonstrates that, while God may have created life, (s)he is not necessary for its creation.
Don't they listen?? (Score:5, Funny)
Their "science" and "bacteria" are going to cause random plot-convenient sex changes and bloody dismemberment of lawyers!!!
...well okay actually maybe this isn't going to be so bad
Re:Don't they listen?? (Score:4, Funny)
You say that as if it's a bad thing.
Misleading Title (Score:5, Informative)
Re:Misleading Title (Score:2, Informative)
Re:Misleading Title (Score:2)
More correctly, it's "synthesizing new organisms". "From Scratch" implies, well, that you started from scratch. i.e. Nothing.
Besides, if you remove DNA/RNA from a cell, is it still a cell and is it still alive?
Irrelevent. We have the technology to reanimate bacteria. However, we don't have the technology to construct a living bateria.
This story is a bit like all those cutsey headlines, "Faster Than Light Achieved! Einstein Wrong!" Then you go read the articl
Re:Misleading Title (Score:4, Funny)
- Carl Sagan
Re:Misleading Title (Score:3, Informative)
Another way of saying the same thing would be that everything is wrong with the summary. After all, this is text we're talking about; isn't meaning the whole point?
Re:Misleading Title (Score:2)
No, not really. If I told you I built a car from scratch, would you think I pimped my ride, or built a completely new vehicle from spare parts? Saying someone created life from scratch suggests abiogenesis, which would be a truly phenomenonal acheivement, whereas gengineering some bacteria is common place.
Re:Misleading Title (Score:3, Insightful)
It would be interesting to try to argue your way around the GPL using that reasoning ('yes your honour I wrote it from scratch using two existing GPL programs that I put together, so the GPL doesn't apply').
The case might last, um... 15 seconds..?
Re:Misleading Title (Score:2, Insightful)
Life truely from scratch is the, ummmm, "Holy Grail" of the life sciences. The true uncharted territory.
This is just another story about genetic engineering.
KFG
Re:Misleading Title (Score:2)
Re:Misleading Title (Score:2)
(I actually do research on the math part of this. And some on the building.)
-Howard
Not only that (Score:2)
"Creating life" is taking Carbon, Hydrogen, Oxygen, Sodium, Chlorine, Phosphorus, etc. and turning that into cells which reproduce.
so they're the tuner generation of biologist (Score:2)
start with a regular old cell then tweak and tune the hell out of it. Then keep dyno'ng the creation until they get what they want.
Re:Misleading Title (Score:5, Funny)
"OK, look God," he said, "We've mastered space exploration, we can cure any disease, we can talk instantaneously with people around the world, we can clone human beings; basically, we don't need you any more."
God listened patiently. Finally He spoke.
"Tell you what," He said. "We'll settle this with a man-making contest. Each of us will make a man, and the first one to finish wins."
"Sure," said the man, who headed off to consult with his colleagues.
"Wait a minute," called God.
The man turned.
"We're going to do this the real way; the way I did it in the beginning."
"No problem," responds the man, bending down to grab a handful of clay.
"No, no, no," says God. "You get your own dirt."
Biohacking (Score:5, Funny)
Scientist #2: LOL j00 r bi -- ur teh ghey!!!
Scientist #1: STFU, n00b!111!
Re:Biohacking (Score:2)
so yeah. you're wrong.
I am going to sue (Score:5, Funny)
God
Re:I am going to sue (Score:5, Funny)
God
Yea right, like you have any lawyers up there!
Re:I am going to sue (Score:2, Offtopic)
But He IS the judge.
Re:I am going to sue (Score:2)
Re:I am going to sue (Score:2)
Hmm (Score:2, Insightful)
Title misleading? (Score:5, Insightful)
Combining the genetic material of different species, I think we can all agree, is hardly creating life from scratch.
Re:Title misleading? (Score:2, Interesting)
Re:Title misleading? (Score:2)
Recipe for pepperoni pizza "from scratch":
Get pizza.
Make pepperoni.
Add second to first.
It's not to say that the scientists aren't working hard, aren't smart, or haven't made a significant advance. They are making new genes and using them in living organisms. This is completely
Hillbilly Engineering (Score:3, Funny)
Hillbillies have been doing this for years.
Re:Title misleading? (Score:2)
Its also illegal in some states, morally wrong in some religions, and offensive to some people. I just think its gross and they should keep that stuff in their bedroom.
Re:Title misleading? (Score:2)
Re:Title misleading? (Score:2)
Combining the genetic material of different species, I think we can all agree, is hardly creating life from scratch.
I guess we don't all agree, because I don't. What does "from scratch" mean? In cooking it means taking basic ingredients and turning that into a finished product. Isn't DNA the basic ingredient to life? In cooking you can still use machines to do some of the work like a mixer, oven, etc and still have your product created "from scratch". Why isn't the same true in biology when you're usin
Creating life? (Score:5, Funny)
Re:Creating life? (Score:2)
Re:Creating life? (Score:2)
I can't believe they would do this (Score:5, Funny)
http://www.venganza.org/ [venganza.org]
Re:Creating life? (Score:2)
We build organisms by mutations all the time (Score:5, Insightful)
and then we crank out thousands of colonies for each of these, or at least we hope we do.
So, from my viewpoint, the concept of manufacturing an organism to crank out oil needs to be thought thru quite a bit - what if it harvests not just the biowaste of corn husks but starts eating grasses and other plant life? what if it hybridizes or mutates (there is solar radiation and chemical interference and ingestion) and loses its species-specific behavior - as bioengineered rice did in China and India when it hybridized with nearby "wild" rice crops due to their farming practices and this thing called nature (wind, storms, excessive rainfall, seeds falling out during transport
Be careful what you wish for - sure you may be able to make a plant that creates oil, but it may end up turning your front yard from grass into sludge, or attack your food crops.
It's happened before, and that's one of the joys of biochemistry - biological processes change and adapt and mutate and it's always fascinating in this multiply interdependent bio system we live in.
Now, if you want to experiment on Mars or in space colonies inside large asteroids, be my guest. But we live here. Just because you can do something doesn't mean you need to do something right now...
Re:We build organisms by mutations all the time (Score:2)
Re:We build organisms by mutations all the time (Score:3, Insightful)
Oh? Did we give up and all die off already?
Re:We build organisms by mutations all the time (Score:2, Insightful)
For humanity and science to grow beyond our current technology, we need viable powersources. I regard fossile fuel like a "rocket booster", when it runs out, we need something to keep us "airborne", technologywise. Fusion technology looks exciting and is supposed to be selfsufficient before long, but if we fail, a backup plan might be useful.
And another thing, antibiotics are falling behind in
Re:We build organisms by mutations all the time (Score:3, Interesting)
We could easily migrate to expanding wind farms and solar farms and biofuel usage - storing stored energy via catalysis (H20 to H2 and O2) in fuel cells fo
Re:We build organisms by mutations all the time (Score:2)
This is extremely unlikely to happen. Different plant species have different proteins and biochemicals, and an organism tailored to deal with the product of one plant is not going to be effective at dealing with those of others. This is why parasitic organisms and infective bacteria, vi
Re:We build organisms by mutations all the time (Score:2, Informative)
No, that's not true. For example, we find Leishmania using canines (dogs) as a reservoir for infection, and then infecting humans.
Cross-species parasitic organisms are fa
Re:We build organisms by mutations all the time (Score:2)
This completely different from some hypothetical 'general' parasite which can happly munch through a large variety of plants. Having very specific org
Who do they think they are? (Score:3, Funny)
Hmm... (Score:2)
stuff (Score:4, Informative)
IDIOTS, when CANABIS is the answer!! and no patent (Score:3, Funny)
"oh lets invent something because the free nature stuff cannot be patented and sold for profits"
Any one can clone natures best, cloning plants is trivial.
So - http://www.hempcar.org/ [hempcar.org]
So if the damn politicans and christian nut cases would just die of cancers overnight, we could have some real prople with brains running the show to everyones benefit not just the corporate elites nutjobs.
IMHO (Score:3, Interesting)
Of course, some people believe that animals deserve the same treatment as humans, but that's another topic.
Re:IMHO (Score:2)
Given the difficulties of building entire intelligent brains from manufactured DNA I think intelligent software will be seen first.
Of course, many of us have created intelligent beings. I have to get back to mine now. He wants his breakfast.
Re:IMHO (Score:2)
Very good point, but you'll soon see 100s of posts by
And, no, I am not saying that one can't think/talk or reason about 'the mind'. It is just that one can only do it in the general context of philosophy where everything remains ambigous (because there are different premises you can choose from).
Re:IMHO (Score:3, Interesting)
And please don't say that we can't detect the mind, so we should treat everything as not having free will and therefore we can do as we please.
Re:IMHO (Score:2)
Mind can't be explained? (Score:2)
The mind (by definition) cannot be explained by science...
You claim the mind, by definition, can't be expolained by science. Mind is in quotations. What is this definition you're referring to? I"m not familiar with it.
I've learned a bit about neural networks and have been impressed with what neural networks with very few neurons (i.e. tens) can do. The human brain has 10's of billions of neurons. That is a huge difference in magnitude! I am not so arogant as to suggest we can presently know what
science (Score:3, Interesting)
Deep theory of biology (Score:4, Interesting)
Some of the scientists involved are saying its more of an art instead of a science due to its 'biohacking' style of experimentation.
Much of biological science consists hacking, trial and error, dubious statistics, and manipulating life with cheap tricks and without deep understanding. I'm glad to hear scientists call as such. Given the daunting complexity of the subject matter, it is not surprising. But I wonder if there is there a deeper 'theory' of biology analogous to least action principles in physics, that could be illuminated by mathematics? Any biochemists or geneticists care to comment?
Re:Deep theory of biology (Score:2)
That ain't right. It's the procedure and methods which are trial-and-error, hacking and statistics. Not the understanding. Biologists and biochemists know what's going on in a cell. What they cannot do, is manipulate that stuff directly.
Cells are very very small things. DNA is very sensitive matter. There is simply no method to insert a given piece of DNA i
Re:Deep theory of biology (Score:2)
That may have been true 30 years ago, but it's not now. In fact, we can predict the dynamics of biological processes, such as gene expression, signal transduction, and metabolism. The hard part about predicting these systems is that _there are so many components_.
Today, mechanical engineers can completely predict how a car with thousands of individual components will behave. Chemical en
Re:Deep theory of biology (Score:3, Insightful)
That may have been true 30 years ago, but it's not now. In fact, we can predict the dynamics of biological processes, such as gene expression, signal transduction, and metabolism. The hard part about predicting these systems is that _there are so many components_.
No, it is still correct today. E.g. the Arrhenius equation describes the dynamics of most chemical reactions. That doesn't
Re:Deep theory of biology (Score:3, Informative)
Less even. Largest our group has done is about 120.
The current solution to that problem is to use a hybrid Quantum Mechanic / Molecular Mechanic (QM/MM) method that only uses ab initio calculations for the atoms located near the catalytic site and use regular molecular dynamic simulations for all other atoms.
Right. But MM is not ab-initio, and DFT QM isn't either if you're a purist. And you still need a reliable structure
So, you're right when you say "you
Obligatory. (Score:2)
Re:Obligatory. (Score:2)
Where Life Started... (Score:2)
Natural foes? (Score:2)
Oh you mean like the polio virus they assembled from parts?
what are the natural foes of a virus? Immune systems, maybe? What else?
Re:Natural foes? (Score:2)
Crocodiles? [slashdot.org]
Um, a little late, perhaps... (Score:2)
he intends to string together genes to create from scratch novel organisms that can produce alternative fuels such as hydrogen and ethanol. [emphasis mine]
Um, we already have a novel organism which can produce ethanol.
It's called yeast.
And it is well understood and has a low risk of becoming an ecological disaster.
Why would we invent a new organism?
Answer (Score:2)
Slavery (Score:3, Funny)
Isn't this a form of slavery?
Re:Slavery (Score:3, Insightful)
And you can't point out that those organisms exist in an environment where they reproduce in numbers that would never be possible in nature. According to them -- well, one person in particular -- "it doesn't matter how loosely we hold the whip; it's still a form of slavery." That's mo
Correction (Score:2)
Re:Correction (Score:2)
stamp out "vitalism" for sure (Score:2)
Vitalism has been used (and still is
Ethenol? (Score:3, Funny)
Also, the obligatory:
I'd like to see a Biowulf cluster of these.
All your biohacks are belong to us!
Re:Ethenol? (Score:2)
And I guess I'll need it when they do.
Re:Ethenol? (Score:2)
Ethenol (CH2-CH-OH) is vinyl alcohol.
So...
Not news (Score:2, Informative)
Something I find more note-worthy, as a biological chemist, is a new trend to expand the amino-acid table (past 20). Many of the codons (DNA or RNA triplets) are degenerate or they are stop codons. The idea is to add synthetic amino-acids to specific tRNAs. Chemically modified amino-acids are inc
nothing to see here (Score:2)
There is neat stuff happening in this area, but there was neat stuff happening before people gave it a new name.
Until what they create has a brain... (Score:3)
Re:Been done? (Score:4, Informative)
While necessary for life, molecules are not living organisms.
Oro's experiment created the base adenine, which is one of 4 nitrogen bases in DNA. Again, not life.
Re:Life in the Lab (Score:2)
Re:Scientists vs. artists (Score:2)
The thing is, the worst they can do is make someone look at goatse or Mr Hands -- they aren't going to turn you into grey goo.
At some point hacker/tinkerers will be doing this stuff, and then a bit later, "artists". There will likely be a lot of problems when this happens.
Now you can design PCBs, send off your files and get PCBs in your hand a few days later. I can imagine there will be sim