Gene Doping: Genetically Engineered Athletes 393
securitas writes "With the Athens 2004 Summer Olympics about to begin, games officials are on the lookout for the use of performance-enhancing drugs by athletes who want to gain an edge over their competitors. Scientific American's H. Lee Sweeney reports on sports officials who are looking to the near future with fear, anticipating a new, undetectable kind of doping that threatens to transform the fundamental nature of sports: gene doping (single-page view). The technology uses new 'therapies that give patients a synthetic gene, which can last for years, producing high amounts of naturally occurring muscle-building chemicals. The chemicals are indistinguishable from their natural counterparts and are only generated locally in the muscle tissue .... so officials will have nothing to detect in a blood or urine test.'
The article from the July 2004 issue includes diagrams by Jen Christiansen on the importance of skeletal muscles that provide athletes' power and how gene doping works.
Is the future of competitive sports an elite cadre of genetically engineered athletes?"
Cybernectics and sports (Score:5, Interesting)
Re: (Score:2)
Re:Cybernectics and sports (Score:2)
"Goo gun". Better assonance, and more flowing. (Kinda like goo itself.)
Re:Cybernectics and sports (Score:3, Funny)
Re:Cybernectics and sports (Score:3, Funny)
Re:Cybernectics and sports (Score:2)
No, the outcry won't begin until an American football team does that.
Re:Cybernectics and sports (Score:2)
Re:Cybernectics and sports (Score:2)
Re:Cybernectics and sports (Score:5, Insightful)
But what about cross-breeding athletes ?
Natural "genetic engineering" won't be outlawed and if artificial genetic engineering becomes an acceptable way of curing/preventing some diseases, it'll be hard to deny athletes access to such medicine...
Oh, and what about athletes using contact lenses? Or shoes? I suspect the organisation wouldn't let an all-natural athlete enter the competition because of nudity
Re:Cybernectics and sports (Score:2)
Re:Cybernectics and sports (Score:2)
Me? I'll probably just ignore the games like I always do. What's the problem?
Re:Cybernectics and sports (Score:2)
I'm the kind of nerd that goes to the jon at work and hopes that someone leaves any part of the newspaper other than the sports section. Today I was of course disapointed yet again.
Seriously though I could care less if someone dopes or not. It's between the athlete and the governing body. I don't see how it effects my life in any way. Which is why I lost alot of repect for W when he mentioned doping at during one the State of the Union address. all the problems in thsi world and we bot
Re:Cybernectics and sports (Score:3, Interesting)
Re:Cybernectics and sports (Score:3, Funny)
Yeah, because his administration has been otherwise impeccable...
Seriously, the only dope problem this country has is the one in the White House.
Re:Cybernectics and sports (Score:2)
Even the best athletes of all times had something going on for them naturally. In other words, they were 'lucky' enough to be a part of natural mutation in their favor (as against gene-doping which is artificial). And of course, after being naturally gifted, they had to work their ass off to get to where they reached.
Lance Armstrong for example has a heart size almost three tim
Re:Cybernectics and sports (Score:3, Interesting)
There's no significant difference between gene tampering, doping, and selective breeding.
It's not like keeping it natural is going to make it so that almost anyone could get there if they only tried hard enough.
To make the games interesting the contestants should be chosen at random from the general population.
Rather than determining if our best is better than their best we could try to determine if our average Joe is better than theirs...
Re:Cybernectics and sports (Score:4, Insightful)
I suspect in that future time sports fans will look back on our current unenhanced sports period the same way we look back on 19th Century sports: with some nostalgia, but shaking our heads at the quaint rules and customs.
Re:Cybernectics and sports (Score:3, Insightful)
Re:Cybernectics and sports (Score:3, Insightful)
Should we forbid eyeglasses? Contact lenses? Laser eye surgery? What about laser eye surgery to take someone from 20/20 vision to 20/10?
We have been using vision correction for hundreds of years, so somehow, we generally view that as "fair". But is it?
I don't have the answers. Argueably, no two athletic competetors are on equal ground except for identical twins/triplets/clones.
(For the record, I am very nearsighted -- anything beyond about 8 inche
Ironic when you consider the ethos of the original (Score:5, Interesting)
Re:Ironic when you consider the ethos of the origi (Score:2)
At least with the Communist (German and Chinese) swimmers that were doping in the 80s and 90s everyone knew they were cheating and it was just accepted that eventually they would be caught.
Sadly, at times, the athletes themselves didn't know they were being fed something other than vitamins. Let's just hope that the athletes that are doing gene doping know that they should be ashamed of their a
Re:Ironic when you consider the ethos of the origi (Score:2)
Communist countries didn't have "true" amateurs. In fact, we were far more pure in that sense than most of the other major powers in the Olympics. The current "Dismal Team" is just that. They are performing terribly against other countries because they have forgotten the essentials we were stre
Re:Ironic when you consider the ethos of the origi (Score:3, Interesting)
Cite your sources (Score:5, Insightful)
Strength (Score:5, Interesting)
Re:Strength (Score:2)
nitpicking... (Score:2)
if you're reporting something, at least get the time right...
Re:nitpicking... (Score:2)
Re:nitpicking... (Score:2)
Re:nitpicking... (Score:3, Funny)
Re:nitpicking... (Score:2)
Besides, 'editor' is a really strong word for the guys at
Re:nitpicking... (Score:2)
Use in MD? (Score:5, Interesting)
Re:Use in MD? (Score:2)
Re:Use in MD? (Score:3, Informative)
Re:Use in MD? (Score:2)
this is definately gonna be something people will be talking about before the next olympics.
Re:Use in MD? (Score:2, Interesting)
The MDA (Muscular Dystrophy Association) has been doing a lot of research on using gene therapy for MD. (I only know this because one of my best friends was told when he was 12 that he'll prolly not live past 16 years of age. He made it to 18 before his body gave out.)
It's been a number of years since I've read anything about it, but last I remember there were two issues with using gene therapy to treat MD.
Gene therapy via viruses can cause cancer & TS (Score:2)
The method of using viruses to introduce genetic changes has been troublesome up to this point. Viruses don't always take over the cell properly and if they don't then the splicing of genetic material causes errors which can lead to all manner of illnesses including toxic shock and cancer [usatoday.com]. Viruses look like a great way to introduce genetic changes until you realize the fight with the body makes it unpredictable and dangerous.
Proposal: Two sets of Athletic competitions (Score:5, Interesting)
I think it would be a great benefit for society, because then the legalized genetic enhancements would become a highly lucrative legimate business that does controlled experiments only on willing participants. What better way of advancing biotech, growth hormone therepies, genetic engineering techniques than funding it with huge sports franchises and only using them on people who want to be using them.
Re:Proposal: Two sets of Athletic competitions (Score:2)
It's a huge and complicated ethical issue.
On the one hand, each person's body is his own and what he does with it is his own business. If he wants e.g. to be a superman at 25 and have major health problems by 35, that's his choice to make.
On the other hand, consider some likely consequences of such an approach.
Conceptually breaking down the notion of "fair". (Score:4, Insightful)
Ideally, olympics should be about who has the most perseverance, dedication, and talent. But this exposes the olympics as essentially rewarding people for having the right genes. Why don't we just examine the genes aka Gattaca and declare the winner beforehand? I realize that reaching a competitive level takes quite a bit of effort, but if genes turn out to be the determining factor, we may as well be just testing DNA.
Re:Conceptually breaking down the notion of "fair" (Score:2)
How many kids on the playground today have the potential genes to become another Michael Jordan, but lack the desire and drive to get there.
Re:Conceptually breaking down the notion of "fair" (Score:2)
breaking down the notion of fair, not really (Score:2, Insightful)
Re:breaking down the notion of fair, not really (Score:3, Insightful)
Never mind fair - its a question of ethics (Score:2, Insightful)
And don't imagine its just an issue of personal choice. That it is not is perfectly clear in team sports where players are asked to "take one for the team" but even in individual sports the pressures to perform make it very hard for individuals to make informed choices.
In an individual spo
Ultra-Mega-Supermodels? (Score:2, Insightful)
Re:Ultra-Mega-Supermodels? (Score:2)
WOW! (Score:2, Funny)
Why not allow these drugs? (Score:2, Interesting)
So what are performance enhancing
Re:Why not allow these drugs? (Score:4, Insightful)
Obligatory All Drug Olympics [piass.org] reference!
The fact is most people don't want to watch sports that require destroying your body to win. They want to see a competition of discipline, determination, and - yes - good genes, not a freak show of folks willing to half their lifespan in order to win.
Re:Why not allow these drugs? (Score:2)
Tyranny. TYRANNY!
Facism doesn't mean what you think it means [wikipedia.org]
Seems very detectable to me (Score:5, Interesting)
Re:Seems very detectable to me (Score:2)
from the way it looks... (Score:5, Insightful)
In my opinion, he's clean, and is being unfairly accused. But in the future, in 20 years, will there be another Lance Armstrong who refuses to take performance enhancing drugs but yet surpasses all of his or her opponents? What will happen to him or her if s/he is accused of gene therapy? What will happen to the incredibly successful athletes who also happen to be honest?
Lance Armstrong, cancer, rehabilitation, speculati (Score:3, Interesting)
- his having had cancer
- his fighting cancer
- his rehabilituation after the cancer
I don't know the facts, so this is entirely speculation based on what other people have said - so don't take this as fact, accusation, or anything else, please - it'll lead up to a more generic question
What if hi
Re:Lance Armstrong, cancer, rehabilitation, specul (Score:3, Insightful)
The thing is, before Armstrong had cancer, his body type was radically different -- broader shoulders, heavier upper body. Chemo destroyed most of his muscle mass, and as a result, when he rebuilt himself, he was able to focus on the muscle groups necessary to win Tours de France. Look at him now and he's got a scrawny upper body compared to the past. That translates into a HUGE advantage in t
Re:Lance Armstrong, cancer, rehabilitation, specul (Score:5, Insightful)
To a large extent, that is what happened. He used to be a triathlete, and had a strong upper body that was good for swimming but mostly dead weight on the bike. When chemotherapy stripped him down to his bones, he built himself back up as a pure cyclist.
Also, while a lot of the European cycling fans and journalists grumble that Lance never shows visible pain during races and is therefore less likable -- if you've seen the clips of him riding just after getting out of chemo, bald, with a hole cut in his skull, you get the impression that he's simply redefined his whole scale of what real suffering is.
It will make the Industrial Revolution (Score:2, Insightful)
Forget the atomic bomb -- if a totalitarian country like North Korea starts fiddling with the genome, the rest of the world will have to follow suit or risk being turned into an irrelevancy. In one hundred years,
Modified class olympics (Score:2)
One problem I could see is that the women sports categories would populated with some very ugly hairy looking women.
Re:Modified class olympics (Score:2)
not if they use laser hair removal and plastic surgery...
As someone asked about Viagra... (Score:2)
Mickey Mouse Olympics (Score:4, Informative)
What about other attributes? (Score:2, Funny)
KHHHAAAAAANNNNNNN!
"Threatens to transform?" (Score:3, Interesting)
Wake up. As our technology advances, life is going to change, sometimes in increments that are uncomfortable to bear. Debates of morality and ethics will constantly shift and evolve. And guess what -- none of this is a "threat."
Ah, "Scientific" American (Score:2)
"Skeletal muscle accounts for more than a third of an average healthy 30-year-old's body mass, but its cells are unlike most human tissues."
Think about that. Thirty five percent of your body is unlike the other sixty five percent. I'd hazard a guess that that would be a true statement for almost any given
Good stuff (Score:2)
If it were safe and avalible, why not get it done? How much healthier would we all be if we were given extra lean muscle, improved joints, stronger bones? And I mean normal people, not just those with disease.
what is the differance?? (Score:2, Interesting)
Isn't the present and past of competitive sports an elite cadre of genetically engineered athletes???
I mean why is genetic engineering though evolution better then consciouse design??
stendec@gmail.com
New rule. (Score:5, Insightful)
Caveat; If you die of 'natural' causes within 5 years after winning the games, ya gotta give the gold back. Fair? Fair!
Like lots of people on this board, I think the whole idea of 'natural' vs. 'unnatural' competition is a little odd. Why is someone who 'naturally' produces more testosterone more ethical than someone who injects it? Shoud certain hormones be restricted to a normal range? Or do we just say 'its gotta be organic.'
Probably at the heart of all this is the question "what's the Olympics about, exactly?"
Doing as well as you can? Testing the limits of human endurance? Then allow modifications.
Overcoming disability? Lets penalize those folks with fewer disabilites, then!
The problem with technology is that it blurs natural boundaries and makes us ask silly philosophical questions like "what does a person have to do to qualify as a human."
The original olympics wasn't about all of this silly ethical garbage. It was about muscular naked men manhandling one another in front of a large audience. I, for one, think we should honor this spirit and seek to preserve it.
Amen.
Lance Armstrong losing his 6th Tour de France... (Score:4, Funny)
...toothpaste, deoderant, and soap.
Re:Lance Armstrong losing his 6th Tour de France.. (Score:2)
"It was reported that Lance Armstrong is about to have his 6th Tour de France title taken away"
Care to cite some sources? Google came up blank.
Re:Lance Armstrong losing his 6th Tour de France.. (Score:2)
(I guess I should've added a comment about never encountering fellow cyclists who actually use deodorant on the morning group rides...)
unlimited category (Score:2)
Am I alone in not giving a damn (Score:3, Interesting)
Then you got tiny countries competing with giants, some of who can afford to spend huge sums of money on training and some who can't. Add events that some countries just can't train, bit hard to learn to sail in a landlocked desert, and what is the point.
Open up the drugs and lets see what we can do to the human body eh? Doctors have to be very carefull in human testing of new drugs but here you got a bunch of idiots^H^H^H^H^H^Hvolunteers who happily pump themselves full of the latest medicine. Most of these performance enhancing drugs can be used in real medicine.
Lets try muscle building medicine in those without social value ehm, in athletes and if it works we can use it in people struck with disease.
The games ain't fair anyway, if they are all pumped up at least that bit balances out.
Re:Am I alone in not giving a damn (Score:2)
From what I've seen, nowhere else comes close to doing this as much as the USA does. If an American doesn't stand a good chance of winning, chances are there'll be no coverage at all. That's an exaggeration, but honestly not much of one. Very sad.
the future of sports (Score:2)
According to "Infinity Welcomes Careful Drivers", yes but they will be banned because they make things boring. The point of no return comes when you get goalies who exactly fill the goal.
Re:the future of sports (Score:2)
Although IIRC then even that won't work for Scotland, who will still manage to lose 2-0.
Free for all (Score:2)
Oh. Great. (Score:3, Interesting)
I do hope people at the Olympic Commitee realize that their games are slowly shifting from sport to engineering?
The question is, once the Olympic Games, as well as a whole other lot of various sports - look at the Tour de France - become a dangerous arena where everything, legal or not, is done to upgrade the athletes to a victory which is the only, absolute goal since we've come to entertain a deeply sick fetishism for any kind of winner, no matter if it was in a fair competition and if he/she deserved it, once sports in general, and the Olympic Games in particular become the field of a elite crew of genetically engineered humans, what will then be the point for such games? Aren't sports from the Olympic perspective a way of celebrating and uniting humanity in competitions that are meant to be fair?
If the athletes become better than normal human beings, not because of training but because of biological engineering, will humanity still identify itself to its champions who would have unnaturally bulky muscles, a blood that could carry insane amounts of oxygen and tightly-controlled metabolisms?
How would these athletes be different from machines, engineered with a precise purpose - and discarded, left out to die afterwards (damn, look at what happened to Marco Pantani)...
Worshipping winners instead of reverring competition in itself is having us slide along a slippery and very dangerous slope, IMO.
- HadrivenAt least, if those victory-obsessed were tinkering with cybernetic bodies or something close - replaceable, tweakable at will... But no, they're playing with their own lives. All that for a victory which means nothing but insane amounts of money.
WILKOMMEN! (Score:2)
Trials in Humans Without MD (Score:5, Interesting)
I'll go out and say it: I'm overweight. And yes, it is my fault. I could get out and exercise a ton, I could eat less, etc, but I find the struggle unrewarding and difficult. In the month of July, I spent most of the month creating a 3D game with another guy my age. He had an average build. As an experiment on top of our research, we decided to try something. He didn't believe me that my being overweight was not a result of my eating more and exercising less than he did. So we equalized our days. We ate all meals together and ate items of equal nutritional value. We also followed identical exercise routines (I can run a few miles no problem, I just don't seem to lose weight unless I run them every day while starving myself). By the end of 3 and a half weeks, I had GAINED 10 pounds and he stayed the same. He was shocked. I was not amused. The routine we settled on was probably was less active than what I do normally to maintain.
I don't want to say I have a slow metabolism or any of those other shitty fat people excuses but I can't help but feel like I was dealt a poor hand by genetics. Muscle is expensive for the body to maintain. If I could have more muscle and have it break down less quickly, it could just help my body eat away at my apparently conserved energy being stored as fat. At the same time, it would make exercising easier by increasing my strength by a third or so. I know I'm interested.
Re:Trials in Humans Without MD (Score:3, Interesting)
Umm... how exactly a lot of muscle mass will help overweight people?
People, generally speaking, get overweight because of problems with their metabolism, problems with their hungry/satiated signals that the body sends to the brain, or psychological problems. None of these problems will be helped by growing more muscles.
I don't want to say I have a slow met
Re:Trials in Humans Without MD (Score:3, Interesting)
People, generally speaking, get overweight because of problems with their metabolism, [...]. None of these problems will be helped by growing more muscles.
Actually, if you do a little research about weight gain, muscle training, and fat burning, you'll learn that increased muscle mass actually results in an increased metabolism, which burns fat. Muscle is "metabolically active," which means it is burning calories even when you're not
Why bother? Human growth hormone (Score:3, Interesting)
Andre the Giant had it, people who suffer from it get those facial features, pronounced brow and nose, etc.
I watched some documentary about it, they showed lots of photos of russian athletes from the cold war era, most of whom shared striking facial similarities with Andre. Beating americans at all costs was the mantra of the Soviet athletic program.
In soviet russia, hormones produce you!
Who cares about the olympics anyways. The IOC is so frigging corrupt it's a joke. They openly accept bribes (hell, demand them!) when chosing cities to host the games.
Its all a corporate jack-fest, like so much these days. McDonalds, the official hamburger of the american olympic team. Come on, how many finely tuned athletes eat Big Macs on a regular basis?
Not in the future... NOW (Score:2)
That means if an athlete is willing to pay someone who can and will do it... then there could (in theory) be genetically enhanced athletes in this olypics.
Absolutely. (Score:2)
What a weird, fucked up world... (Score:4, Interesting)
In other words, it's okay for rich countries like the US to use technology to optimize the performance of their athletes, to the detriment of those in poorer countries who do not have such advantages.
And yet, it is considered sacriligious to "violate" the spirit of competition by taking a few performance-enhancing drugs here and there?
Re:What a weird, fucked up world... (Score:3, Interesting)
So, here's my proposal - allow any given athlete to receive a certain amount of funding, but put an upper limit on it. Let them get contributions to allow them to buy decent equipment, and to travel to competitions, etc, but not allow them multi-million-dollar research facilities, and so on.
Yeah, there's still potent
This just highlights the inherent meaninglessness (Score:3, Interesting)
So what's the problem? Some people are born with genes that enable them to be better athletes. Now some people want to emulate that. Sure, it seems like cheating to me, but if someone has super muscles naturally that seems unfair as well. What the are we trying to test in the olympics anyways? Skill? Will? Natural genetic perfection? A combination of all three?
Seems to me that the focus on superlatives (as opposed to just excellence), combined with globalization, has forced us into a corner. What is the point of superlatives, anyways? What do we really want to know?
Also, I don't know if I think genetic manipulation is any less ethical than brainwashing children to devote their life to perfection in a single pursuit before they've had a chance to experience anything else.
As far as I'm concerned, the whole Olympic thing is just a big commercial opportunity. I'm all for individuals being their best, and competing. But it's just so dirty now and it doesn't seem to serve any meaningful purpose.
Just my take.
Cheers.
PS -- Speaking of testing will: I once broke my arm in an arm wrestling match. Seriously. This means I had the will and strength to torque my own humerus (with the help of an equally strong friend) until it spiral fractured. I don't know what it proved, but I would say it's the superlative of something
It was just a matter of time (Score:3, Interesting)
Somewhere I read how one participant at a beauty contest admitted she'd fixed her looks and then other participants requested her disqualification.
She was the only "enhanced" beauty - she was the only honest one.
So what can we do? Can we draw a line?
A corrective surgery disqualifies you but another emergency surgery to fix broken nose from a traffic accident doesn't?
Or bar every one who's ever "went under the knife" from participation? Are braces illegal because they're used instead of corrective teeth surgery?
The same is with sports - why can one individual have a mutated gene and I can't? Since it's not "natural" (as in "common"), why only him/her?
One way to make it fair is to make everything allowed. Of course for many that will have bad consequences for their health, but so do current "enhancers" that cannot be detected. And ultimately it is up to the athlete to make a decision - as is now.
Can they disallow that? It's undetectable and "natural" - unless they expand testing to athletes' parents and families there's no way they can detect if a gene or whatever is natural or mutated.
Coaches should have criminal responsibility for providing athletes with dangerious/harmful substances to keep coaches in the check.
While it's not easy to say what is just "bad for you" and what is really dangerous, but at least reasonable due dilligence would suffice.
I do think the _current_ system is unfair - people with disabilities cannot compete at all, people with "normal" genes aren't (very) competitive. So the system is biased in favor of the few sprinkled with couple genetic anomalies (=improvements).
And finally - bring the whole genetic performance enhancing idea to education - woooo hoooo!
Since the society is powered by greed, most people will give their kids anything to make them better off...
This is only the beginning...
Re:Eureka! (Score:3, Funny)
If only there was a +1, Pity...
Re:Eureka! (Score:3, Insightful)
"This explains all of
Although given the comments in the "Total Cost of 0wnership" thread, that was apparently a package deal with the gullibility gene. ;-)
Seek Not The Score (Score:2)
"Strangely, the 2 replies that others have posted in regards to my attempt are outscoring me. This whole "no longer an AC" thing isn't all it was cracked up to be."
Ah grasshopper, the first step in gaining karma is to realize that there is no score . Post freely, and with forethought. What follows will follow.
To the mods (Score:2)
This post represents everything slashdot is about:
-Elitism
Fact is most of the posters seem to think themselves above normal people. This post pokes at that in an annoyingly obvious, but still valid way.
In addition it uses one of the many slashdottisms that slashdotters as a group use to differentiate themselves. Sure he didn't refer to a beowulf cluster of hot grits Natalie Portman overlords bio-engineering (in Japan) you (in Soviet Russia), but he did include one, and that's wo
Re:Nonsense (Score:2)
I think you mean Gattaca. I wonder how many people think that's just a weird title that has nothing to do with the story...?
Re:GATACCA (Score:2)
Re:First tell me this.. (Score:2)
Re:Athletes ? (Score:2)
Re:The problem is demand, not supply (Score:2)
I was, too, but I'm not bitter about it.
That you happen to dislike sports doesn't make them any less worthwhile than wasting time posting to slashdot about how idiotic you think they are.
Your argument is bogus, anyway. Evolution, if it happened, is blind in a manner of speaking, and didn't have a purpose in mind when it gave us large brains. It was certainly quite some time before we figured out how to avoid lifting heavy things and running from predato
Re:Sure... (Score:2)