Glowing Fish are First Genetically Engineered Pets 361
securitas writes "It was bound to happen. Texas-based biotechnology company Yorktown Technologies will start selling a 'genetically engineered aquarium fish that glows in the dark.' The trademarked GloFish -- 'a tropical zebra fish infused with the gene of a sea anemone that makes it glow fluorescent red' -- is first genetically engineered pet. The possible consequences of introducing a new trangenic species into the environment has touched off a debate that has critics such as the National Academies of Science and the Center for Food Safety calling for a ban on the sale of the fish unless the FDA regulates and approves it. The fish go on sale in January 2004. You can see photos of the GloFish here. Cool, but it's no Blinky." M : I think these guys are marketing the fish for a Taiwanese company.
Bummer (Score:5, Funny)
What if a fluorescent zebra fish is eaten? Eating a fluorescent zebra fish is the same as eating any other zebra fish. Their fluorescence is derived from a naturally occurring gene and is completely safe for the environment. Just as eating a blue fish would not turn a predator blue, eating a fluorescent fish would not make a predator fluoresce.
Bummer, I was hoping to see fluorescent cats!
Re:Bummer (Score:2, Interesting)
You have seen the Fluorescent bunny [ekac.org] haven't you? Its fluorescence doesn't come from eating a fluorescent fish, though. It was genetically modified to expressed GFP.
Re:Bummer (Score:2)
Re:Bummer (Score:5, Funny)
Re:Bummer (Score:2)
Will shit glow in the dark (Score:4, Funny)
Re:Will shit glow in the dark (Score:4, Funny)
What if it's a glowing see through fish as well...
I guess what I want to know is what are the chances of getting see through glowing shit?
A Real Challenge (Score:5, Funny)
I've had about 5 fish, only one of them lived longer than a week.
Re:A Real Challenge (Score:5, Funny)
Re:A Real Challenge (Score:2)
First I though they *jumped* out...
...but it seems I have a (bad) cat!
Re:A Real Challenge (Score:3, Informative)
I have 3 zebra danios, and considering how little I actually clean my aquarium, they are extremely resilient little fish. I'm talking on-par with goldfish as far as hardiness. There is also a long-fin variety of danios that are quite pretty, I'd like to see some glow in the dark long finned ones.
Anyway, my point is, any idiot that can keep half-way decent water in a tank, should be able to kee
Re:A Real Challenge (Score:2)
Ultimate Case Mod (Score:5, Funny)
Who needs cold cathodes?
Novelty Item (Score:5, Insightful)
Re:Novelty Item (Score:5, Funny)
Re:Novelty Item (Score:2)
For example they would make a way cool lighting system if you had transparent walls or tanks inserted into walls for bars or very expensive houses.
Re:Novelty Item (Score:2)
Re:Novelty Item (Score:5, Insightful)
This is just a side effect of a useful experiment, why not make some money from it and raise awareness for genetic engineering?
Re:Novelty Item (Score:5, Informative)
Genetic engineering is hard work. Just as mechanical engineers build prototypes to test their ideas before going into full-scale production, so do genetic engineers (and, actually, every other type of engineer I can think of.) As I mentioned in another post, we breed glowing mice at my work; it took about five years of basic research and another three years of trial and error to get a strain of true-breeding* GFP** mice.
Are these mice useful for anything in themselves? Well, actually, they are; it turns out the GFP gene is a useful marker for other genes that don't express quite so dramatically. But that really wasn't the point. The point was to learn how to implant certain genes -- say, genes that are a risk factor for certain kinds of cancer, or genes for resistance to AIDS, or genes to produce useful drugs -- in a true-breeding strain of mice. Now that technology is understood, and it can usefully be applied to all the examples I gave and many more.
No one gets upset when Ford builds a concept car, for God's sake.
---
* True-breeding means that the children of parents with these characteristics will reliably have the characteristics themselves.
** Green Fluorescent Protein. IIRC, originally found in jellyfish.
Re:Novelty Item (Score:3, Informative)
Here in SW Florida, we have a big problem with Australian Paper trees. They look like a Birch sorta with this peeling thin paper like bark. While they are a hayfever hazard, the worse is what they do the environment. They suck all the water out of the water tables.
Even worse, when you chop dow n the trees, they release thier seeds. So you need to poison the trees first, then wait a week to chop them down.
There is a big tree problem in SWF, and it is a slow expensiv
Re:Novelty Item (Score:2)
And though it initially invites backlash from stupid "eco" groups, if GM pets make it to ordinary items, it will on the long term LESSEN the unrational fears general public has towards genetical research, which would be good for useful research as well.
Re:okay (Score:2)
Re:Novelty Item (Score:2)
Re:Novelty Item (Score:2)
Re:Novelty Item (Score:2)
Re:Novelty Item (Score:5, Informative)
Where do fluorescent zebra fish come from?
Fluorescent zebra fish were specially bred to help detect environmental pollutants. By adding a natural fluorescence gene to the fish, scientists are able to quickly and easily determine when our waterways are contaminated. The first step in developing these pollution detecting fish was to create fish that would be fluorescent all the time. It was only recently that scientists realized the public's interest in sharing the benefits of this research. We call this the GloFish (TM) fluorescent fish.
Thinking about he food chain.... (Score:3, Funny)
I bet cats will indirectly become the second
Note the Seattle Times article (Score:2)
They've already done fluorescence with mice, I believe. And glow-in-the-dark cats would be useful, so cars can see them as they dart across the street.
Old news (Score:5, Informative)
Here [enn.com] or here [mongabay.com]
Re:Old news (Score:2)
Excellent news for cat haters (Score:2)
Honolulu technique (Score:5, Interesting)
http://starbulletin.com/2001/02/06/news/story11
red eh? (Score:3, Funny)
Why fish? (Score:2)
Re:Why fish? (Score:2)
Why pray tell would you want a powerful predator for a pet? Even at 1/8 size it will still be a vicious beastie with sharp pointy teeth and quite capable of inflicting serious damage on you.
Re:Why fish? (Score:2)
So is my cat.
Re:Why fish? (Score:2)
Re:Why fish? (Score:2)
I, for one, will welcome our new miniature sabre tooth domestic cat overlords... err, wouldn't want one biting my finger off, that is.
Re:Why fish? (Score:2)
And to actually answer your question, It'd be a cool, unique pet, and I already like cats a lot. Plus, why not? I suppose in a worst-case scenario, it being 1/8 normal size plus th
Re:Why fish? (Score:2)
My house cats are 'serious' predators and often take out rabbits and the occasional village of chipmunks (often leaving a nice head or fluffy tail as a present for me at the back door.)
Fact is MOST 'domesticated' (???) cats are still serious predators. So why NOT a Sabre Tooth?
Take your average house cat at 7-13 pounds. X8 it up, and you have a nice large man eating feline.
Re:Why fish? (Score:2)
Yeah, domesticated. They've been bred for centuries by humans to be companions. That makes your average household cat domesticated. The fact that your cat or my dog can't survive in the wild doesn't mean it's not domesticated.
GloFish not as cool as Dopefish (Score:2, Funny)
Illiad saw it coming! (Score:4, Interesting)
Uh no (Score:2)
Wrong. (Score:5, Insightful)
The methods used may be different but just about every breed of dog known to Man has been 'genetically engineered.' For example, I have a Boston Terrier. The Boston was created in 1857 as a dog fighter by breeding English Bulldogs and English Terriers. Therefore, the Boston was engineered. Take any dog and you'll find that someone wanted a dog that could do this or that or was such a size so they went about selecting different existing species and breeding them to create their perfect dog. So many people think that genetic engineering is done with test tubes but any time two species are brought together artificially you are engineering genetics. Mendel was a genetic engineer and he lived in the 1100s.
Re:Wrong. (Score:3, Informative)
Did you mean Gregor Mendel [accessexcellence.org] (1822-1884)?
Furthermore, Mendel worked primarily with traits of pea plants, which clearly could intermingle in nature. The same is true with dogs - I think if you look around you will find they are not terribly particular about who, when, or where they, ur, cross-breed with.
I think that the questions most people have about altering DNA stem (pun intended) from the fact that humans are creating results that could never occur in nature.
Re:Wrong. (Score:3, Insightful)
Really? That'd be a neat trick. If you are successful in breeding different species you get infertile offspring - that's what species are, different groups that don't crossbreed to produce fertile offspring. Like crossing a donkey and a horse to make a (normally infertile) mule.
Now taking two different breeds of dogs (which are both from the same species) and crossbreeding is a type of artificial selection,
No (Score:2)
Re:No (Score:2)
Re:Wrong. (Score:2)
It's still bit hokey, but much less so if you exclude those few screwed up examples.
Re:Wrong. (Score:5, Informative)
From m-w.com:
transgenic - Having chromosomes into which one or more heterologous genes have been incorporated either artificially or naturally
heterologous - derived from a different species
The article says: "a tropical zebra fish infused with the gene of a sea anemone that makes it glow fluorescent red." Im no fish expert but i dont think you can breed fish with sea anemones.
For your analogy to work, you would have to say something like english bulldogs received genes from a silk spider and now has silky smooth dog turds and can walk up walls.
Re:Wrong. (Score:2)
Re:Mod parent up (Score:3, Informative)
Not dogs: Zebra fish + sea anemone != offspring (Score:2)
A small nitpick regarding your terminology: two organisms that are able to breed to produce offspring are by definition the same species. While you could argue that the Boston Terri
Re:Not dogs: Zebra fish + sea anemone != offspring (Score:2)
That may be the geneticist's definition, but it isn't common usage. Most people consider lions and tigers to be different species.
Re:Not dogs: Zebra fish + sea anemone != offspring (Score:3, Interesting)
Biology (Score:3, Interesting)
Incorrect. There are breeds of dog that cannot safely interbreed, yet they are all considered the same species. On the other hand, cross-species breeding can happen -- horses and donkeys, lions and tigers, and several "jungle" cats with domestic cats can, even sometimes producing fertile offspring [bbc.co.uk].
(And that, of course, doesn't even consider the vast numbers of asexual
Re:Wrong. (Score:2)
The properties of final "product" may derive from genetics (or properties of very small particles in case of nanotech) but those haven't really been fine tuned. Engineering, sure, but not genetic engineering.
And different dog breeds are NOT different species. Different species can not, by definition, interbreed and produce fertile descendants (though there are rare exceptions). All dogs of all breeds fall i
Not wrong (Score:3, Insightful)
(Two people of a different race having children isn't genetic engineering.)
And genetic engineering which completely removes the neccessity for having two creatures have sex to mix the genes. The entire process is dependent on human intervention.
The former is natural selection. The latter is intelligent design.
This fish was given genes from a species it could never natur
Not "glow-in-the-dark" (Score:5, Funny)
Need fish with luciferase enzymes (Score:3, Interesting)
Soooo... (Score:2, Interesting)
They can't breed (Score:2)
Re:Soooo... (Score:2)
Anyways, while your comment is probably correct, it would still be quite fascinating to see these glowing fish replace their ordinary brothers in the wild, _if_ the glowing aspect gives them any higher probability to survive.
Re:Soooo... (Score:2)
Why we make glowing animals (Score:5, Informative)
Re:Why we make glowing animals (Score:2)
I would appreciate it if you did not call Mr. Swim Swim names. Pets have feelings too. : P
What I find most apalling... (Score:2, Insightful)
I realise that there will be things that are genetically altered for the worse. They will either be an experiment or from the mind of someone who intends to do wrong. this is where t
Evil Fish! (Score:3, Funny)
Anchovies (Score:2, Funny)
Pan ring (Score:2)
But wouldn't you need one ring on the pizza pan to keep the pizza from falling apart? You know, to bring the ingredients together and in the darkness bind them? (Or was that olive oil?)
Control (Score:2)
Simon
These DO NOT glow in the dark (Score:5, Informative)
These "GloFish" DO NOT glow in the dark. They fluoresce red under a black light (UV radiation, for those of us who care). But from everything I've read, they don't emit any light at all in the absence of external UV. None. So, that pretty much makes them "Glow-in-the-LIGHT fish."
Now, I'm not entirely suprised that the NYTimes doesn't understand that difference, but slashdotters should be able to.
Re:These DO NOT glow in the dark (Score:2, Funny)
The issue at hand (Score:2)
I can see the "SCO sues over GloFishes' IP" jokes already. But think about it: med labs will eventually come up with gene therapies for more common genetic illnesses (glaucoma, some forms of diabetes, etc...). That would mean patients treated with such therapies would hold some the labs' copyrighted DNA in their body, which would get replicated on ARN and transmitted, etc... Will
So long... (Score:2)
Cancer-fighting Fish! (Score:2, Interesting)
Perhaps not the first GE pets! (Score:2)
Re:Perhaps not the first GE pets! (Score:2)
http://www.transgenicpets.com/default.htm [transgenicpets.com]
Too bad, could someone please fund these guys?
Steve
Yay! Play God! (Score:2)
Glowy fish are good! I want some!
I can assure the world (Score:5, Funny)
I can assure the world that I am Mostly Harmless.
Cabbits (Score:3, Funny)
Eat at Mel's. (Score:2)
Even if a few sexually active specimen get into the wild, I doubt a fish that is unable to turn off its "come and eat me" sign is going to last long enough to find a mate that isn't already scared-off by the horny lightbulb trying to have sex with it.
= 9J =
Yep, as stated...Taiwan had these since July (Score:2)
Texas = slow
The mindless anti-GM zelots really piss me off (Score:3, Insightful)
I am not saying "all GM is good, let's go" - quite the contrary:
The mindless anti-GM zelots can prevent things that really help - I would love to see a GM crop that fixed nitrogen like a legume, yielded lots of bio-desiel and plastic precursors, and could be grown year after year in brackish soil, concentrating the salt in the stalks - imagine the boost to the environment and the boost to the third world farmer! But you can bet that, even if an RMS-inspired botanist created such a crop and released it free of charge (think George Washington Carver), the mindless anti-GMers would prevent it from seeing the light of day!
In short, BE worried about things, but have a clearly reasoned, well thought through idea of WHY you are worried - not just because the thing has "scary" words in it like "genetically modified", "nuclear", or "diesel"!
Re:The mindless anti-GM zelots really piss me off (Score:3, Insightful)
I think you attribute far too much power to the 'anti-GMers'. Here in the US the 'mindless anti-GMers' (all twelve of them) have essentially been powerless to do anything. At this point in time in the US corporate interests trump any others, and Monsanto has been given a free pass to do whatever
These fish are sterlized... (Score:2, Informative)
It sure beats the old method (Score:3, Informative)
Much better for the individual fish.
Nice, but... (Score:2)
best online comic strip, has advocated the
EvilPhish(TM)
a couple of weeks ago...
Happy fish have baby fish (Score:5, Interesting)
Since the fish is covered by patent, what happens to the next generations? Are aquarists going to fall into the same trap as farmers, where they can't replant patented products?
We need an open-source glowing fish!! (Score:2, Interesting)
Who wants to join my GNU/Fish project ?
Multi-coloured fish (Score:2)
They also plan to introduce multicolour fluorescent pet fish, including red, purple and blue.
It would be interesting to see where the gene is being added. If it were in the right place (skin development) then you could have stripy glow-in-the-dark fish.
Hold the presses! 5 month old news! (Score:3, Informative)
Offtopic?!?! (Score:2)
Last I checked 5 assed monkeys were a GM pet.
Re:Offtopic?!?! (Score:2)
Re:Attack of the mutant fish (Score:2)
Re:The first? (Score:2)
If you find it 'not acceptable' then please, don't buy one.
Re:The first? (Score:2)
I'm telling you to mind your own business. Is that more clear to you, or are you just thick?
Re:Yumm (Score:2)
What if a fluorescent zebra fish is eaten?
Eating a fluorescent zebra fish is the same as eating any other zebra fish. Their fluorescence is derived from a naturally occurring gene and is completely safe for the environment. Just as eating a blue fish would not turn a predator blue, eating a fluorescent fish would not make a predator fluoresce.
So i guess it depends on if regular zebra fish are poisonous to humans
Re:Voodoo Antiscience (Score:2, Informative)
The antis are worried about what might happen when these fish are released into the wild, as inevitably happens to a fair proportion of any pet species. You may not be going to eat the things, but predators are. And you might end up eating one of the predators. Hence the FDA connection.
It's paranoia, perhaps, but it's a question that's worth asking nonetheless. If the sellers can convince the authorities that t